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The map label for this gene is comM [H]

Identifier: 124265363

GI number: 124265363

Start: 182883

End: 184487

Strand: Reverse

Name: comM [H]

Synonym: Mpe_A0170

Alternate gene names: 124265363

Gene position: 184487-182883 (Counterclockwise)

Preceding gene: 124265368

Following gene: 124265360

Centisome position: 4.56

GC content: 71.28

Gene sequence:

>1605_bases
TTGGCACCCCTGCGGTGCCAAAGTGCGAGCCAACCACCCTTCGGTGGGCTCGTGGTGGCGGAGGCGCGATGCCATGATCG
ATCGGACATGTCGCTCGCCGTTGTCCACAGCCGTGCTCTCGATGGGCTCGATGCCCCCGAAGTCACCGTCGAGGTGCATC
TGGCGAACGGTCTGCCGAGTTTCACGCTCGTCGGTCTGGCCGACACCGAAGTCAAGGAGGCGCGTGAGCGAGTCCGTGCC
GCACTGCTGAACAGCGGCCTGGCGTTTCCCCACAACCAGCGCATCACGGTCAATCTGGCGCCAGCCGATCTGCCCAAGGA
GTCGGGCCGCTTCGACCTGCCGATCGCGCTGGGCATCCTGGCCGCCAGCGGCCAGATCGATGCGGGGCGACTGGCCGATC
TGGAGTTCGCCGGAGAGTTGTCGCTCGCCGGCGACCTGCGGCCGGTACGGGGTGCGCTGGCGATGGCGCTGGCCGCGCGA
CATGAGGGCCGGGAACGCCCGCTGGTGCTGCCGGACCCGAGTGCGCGCGAGGCCGCCTTGATCGAAGGACTGCAGGTGCG
CTCCGCCAAGCACTTGCTCGACGTGGTCAGTGCGCTGCTGCCCGGCGACGCAGCGCAGCCCCTGTCGGCGGCCACGCCCT
GGCCGCGTCCGCCGACGGCACCCCGGTGGGGCGAGTTGCGCGACGTGAAGGGGCAAGCCGCCGCCAAGCGCGCGCTCGAG
GTTGCCGCGGCGGGCCAGCACAGCGTGCTGCTGGTCGGTCCACCAGGGGCCGGCAAGTCGATGCTGGCGCAGCGCTTCGC
CGGCCTGCTGCCACCGCTGAGCGACGAACAGGCGCTGGAGTCCGCGGCCGTGCTGAGCCTGGTGGGACGCTTCGACGCCG
GTCGCTGGCGCGAGCGCGTGCTGCGTGCCCCGCACCACAGTGCTTCCGCGGTCGCGCTGGTCGGCGGCGGATCACCACCG
CGGCCGGGCGAGATTTCGCTGGCTCATCACGGCGTGCTGTTCCTCGACGAGTGGCCGGAGTTTCCTCGCGCCGCGCTGGA
GGCCCTGCGTGAGCCCTTGGAAACGGGTCGCATCACGATCTCGCGCGCGGCGCGCCAGGCCGAATTCCCCGCGCGCTTCC
AGTTGATCGCGGCGATGAACCCCTGCCCTTGCGGCCACGCCGGCTCCACATTGAGAACCTGCCGCTGCTCCAGCGACATG
GTGGCTCGTTACCAGGGCCGCATCAGCGGCCCGCTGCTCGACCGCATCGACCTGCAGGTGGAGGTGCCGGCGGTCGGCCC
CGAGGCGCTGTCGGCCCTTCCCGACGGAGACCCGAGCGAGGCCGTCGCCGAACGTGCCGCACGAGCGCGCGAACGGCAGC
ACCGGCGCCAGGGTTGCAGCAACGCATTCCTCGACAGCAACGGCATCGACACACACGTGGCGATCGAGCCCGGTGCGGCG
CAGTTCATGCAGGCCACGTCCTTGCGACTCGGTTGGTCGGCTCGCGGCCAGCACCGCCTGTTGCGGGTGGCGCGCACCAT
CGCCGACCTGGCCGGTGCCGAGCACATCGGTGTCGGCCACGTGGCCGAGGCGATCCAGTACCGCCGCGTGCTGGCGGCAG
GCTGA

Upstream 100 bases:

>100_bases
ACTCAGCAGGTTCTGTGCCACTGCGCCATAACAGGGAGTCGCGAGCCGAACCGGGGACGCTTGTATCGGTGGCGCCCCAA
AACAGGGATGTCTGCAACTT

Downstream 100 bases:

>100_bases
ACGAACGGGCCCTTTGACTCGACGCGCGCGCTCAGGCGGCGCGCAGCGTCGTTCCGTCGACCTTGACCCGCGCACCGACC
GCCGGCGCCTGCGACTGCTG

Product: putative Mg(2+) chelatase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 534; Mature: 533

Protein sequence:

>534_residues
MAPLRCQSASQPPFGGLVVAEARCHDRSDMSLAVVHSRALDGLDAPEVTVEVHLANGLPSFTLVGLADTEVKEARERVRA
ALLNSGLAFPHNQRITVNLAPADLPKESGRFDLPIALGILAASGQIDAGRLADLEFAGELSLAGDLRPVRGALAMALAAR
HEGRERPLVLPDPSAREAALIEGLQVRSAKHLLDVVSALLPGDAAQPLSAATPWPRPPTAPRWGELRDVKGQAAAKRALE
VAAAGQHSVLLVGPPGAGKSMLAQRFAGLLPPLSDEQALESAAVLSLVGRFDAGRWRERVLRAPHHSASAVALVGGGSPP
RPGEISLAHHGVLFLDEWPEFPRAALEALREPLETGRITISRAARQAEFPARFQLIAAMNPCPCGHAGSTLRTCRCSSDM
VARYQGRISGPLLDRIDLQVEVPAVGPEALSALPDGDPSEAVAERAARARERQHRRQGCSNAFLDSNGIDTHVAIEPGAA
QFMQATSLRLGWSARGQHRLLRVARTIADLAGAEHIGVGHVAEAIQYRRVLAAG

Sequences:

>Translated_534_residues
MAPLRCQSASQPPFGGLVVAEARCHDRSDMSLAVVHSRALDGLDAPEVTVEVHLANGLPSFTLVGLADTEVKEARERVRA
ALLNSGLAFPHNQRITVNLAPADLPKESGRFDLPIALGILAASGQIDAGRLADLEFAGELSLAGDLRPVRGALAMALAAR
HEGRERPLVLPDPSAREAALIEGLQVRSAKHLLDVVSALLPGDAAQPLSAATPWPRPPTAPRWGELRDVKGQAAAKRALE
VAAAGQHSVLLVGPPGAGKSMLAQRFAGLLPPLSDEQALESAAVLSLVGRFDAGRWRERVLRAPHHSASAVALVGGGSPP
RPGEISLAHHGVLFLDEWPEFPRAALEALREPLETGRITISRAARQAEFPARFQLIAAMNPCPCGHAGSTLRTCRCSSDM
VARYQGRISGPLLDRIDLQVEVPAVGPEALSALPDGDPSEAVAERAARARERQHRRQGCSNAFLDSNGIDTHVAIEPGAA
QFMQATSLRLGWSARGQHRLLRVARTIADLAGAEHIGVGHVAEAIQYRRVLAAG
>Mature_533_residues
APLRCQSASQPPFGGLVVAEARCHDRSDMSLAVVHSRALDGLDAPEVTVEVHLANGLPSFTLVGLADTEVKEARERVRAA
LLNSGLAFPHNQRITVNLAPADLPKESGRFDLPIALGILAASGQIDAGRLADLEFAGELSLAGDLRPVRGALAMALAARH
EGRERPLVLPDPSAREAALIEGLQVRSAKHLLDVVSALLPGDAAQPLSAATPWPRPPTAPRWGELRDVKGQAAAKRALEV
AAAGQHSVLLVGPPGAGKSMLAQRFAGLLPPLSDEQALESAAVLSLVGRFDAGRWRERVLRAPHHSASAVALVGGGSPPR
PGEISLAHHGVLFLDEWPEFPRAALEALREPLETGRITISRAARQAEFPARFQLIAAMNPCPCGHAGSTLRTCRCSSDMV
ARYQGRISGPLLDRIDLQVEVPAVGPEALSALPDGDPSEAVAERAARARERQHRRQGCSNAFLDSNGIDTHVAIEPGAAQ
FMQATSLRLGWSARGQHRLLRVARTIADLAGAEHIGVGHVAEAIQYRRVLAAG

Specific function: Induced during competence development. Not needed for DNA uptake. May be involved in a recombination step [H]

COG id: COG0606

COG function: function code O; Predicted ATPase with chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily [H]

Homologues:

Organism=Escherichia coli, GI145693202, Length=506, Percent_Identity=49.802371541502, Blast_Score=447, Evalue=1e-127,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR001208
- InterPro:   IPR004482
- InterPro:   IPR000523
- InterPro:   IPR020568 [H]

Pfam domain/function: PF01078 Mg_chelatase [H]

EC number: NA

Molecular weight: Translated: 56509; Mature: 56378

Theoretical pI: Translated: 7.69; Mature: 7.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPLRCQSASQPPFGGLVVAEARCHDRSDMSLAVVHSRALDGLDAPEVTVEVHLANGLPS
CCCCCCCCCCCCCCCCEEEEECCCCCCCCCEEEEEEHHHHCCCCCCCEEEEEEECCCCCC
FTLVGLADTEVKEARERVRAALLNSGLAFPHNQRITVNLAPADLPKESGRFDLPIALGIL
EEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCCCCCCHHEEEE
AASGQIDAGRLADLEFAGELSLAGDLRPVRGALAMALAARHEGRERPLVLPDPSAREAAL
EECCCCCCCCEECEEECCCEECCCCCHHHHHHHHHHHHHHHCCCCCCEECCCCCCHHHHH
IEGLQVRSAKHLLDVVSALLPGDAAQPLSAATPWPRPPTAPRWGELRDVKGQAAAKRALE
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCHHHHHHHHHH
VAAAGQHSVLLVGPPGAGKSMLAQRFAGLLPPLSDEQALESAAVLSLVGRFDAGRWRERV
HHCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHH
LRAPHHSASAVALVGGGSPPRPGEISLAHHGVLFLDEWPEFPRAALEALREPLETGRITI
HHCCCCCCCEEEEEECCCCCCCCEEEEEECCEEEECCCCCCHHHHHHHHHHHHHHCCEEE
SRAARQAEFPARFQLIAAMNPCPCGHAGSTLRTCRCSSDMVARYQGRISGPLLDRIDLQV
EHHHHHCCCCHHEEEEEECCCCCCCCCCCCHHEECCCHHHHHHHCCCCCCCCCEEEEEEE
EVPAVGPEALSALPDGDPSEAVAERAARARERQHRRQGCSNAFLDSNGIDTHVAIEPGAA
ECCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCHH
QFMQATSLRLGWSARGQHRLLRVARTIADLAGAEHIGVGHVAEAIQYRRVLAAG
HHHHHHHHEECCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
APLRCQSASQPPFGGLVVAEARCHDRSDMSLAVVHSRALDGLDAPEVTVEVHLANGLPS
CCCCCCCCCCCCCCCEEEEECCCCCCCCCEEEEEEHHHHCCCCCCCEEEEEEECCCCCC
FTLVGLADTEVKEARERVRAALLNSGLAFPHNQRITVNLAPADLPKESGRFDLPIALGIL
EEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCCCCCCHHEEEE
AASGQIDAGRLADLEFAGELSLAGDLRPVRGALAMALAARHEGRERPLVLPDPSAREAAL
EECCCCCCCCEECEEECCCEECCCCCHHHHHHHHHHHHHHHCCCCCCEECCCCCCHHHHH
IEGLQVRSAKHLLDVVSALLPGDAAQPLSAATPWPRPPTAPRWGELRDVKGQAAAKRALE
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCHHHHHHHHHH
VAAAGQHSVLLVGPPGAGKSMLAQRFAGLLPPLSDEQALESAAVLSLVGRFDAGRWRERV
HHCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHH
LRAPHHSASAVALVGGGSPPRPGEISLAHHGVLFLDEWPEFPRAALEALREPLETGRITI
HHCCCCCCCEEEEEECCCCCCCCEEEEEECCEEEECCCCCCHHHHHHHHHHHHHHCCEEE
SRAARQAEFPARFQLIAAMNPCPCGHAGSTLRTCRCSSDMVARYQGRISGPLLDRIDLQV
EHHHHHCCCCHHEEEEEECCCCCCCCCCCCHHEECCCHHHHHHHCCCCCCCCCEEEEEEE
EVPAVGPEALSALPDGDPSEAVAERAARARERQHRRQGCSNAFLDSNGIDTHVAIEPGAA
ECCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCHH
QFMQATSLRLGWSARGQHRLLRVARTIADLAGAEHIGVGHVAEAIQYRRVLAAG
HHHHHHHHEECCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800; 9457884 [H]