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The map label for this gene is dinG [H]

Identifier: 124265242

GI number: 124265242

Start: 46842

End: 47468

Strand: Direct

Name: dinG [H]

Synonym: Mpe_A0049

Alternate gene names: 124265242

Gene position: 46842-47468 (Clockwise)

Preceding gene: 124265238

Following gene: 124265243

Centisome position: 1.16

GC content: 73.68

Gene sequence:

>627_bases
ATGGAAACCATCGCCGTCATCGACTTCGAAACCACCGGCATCTCGCCCGGCCAGGGCGCGCGCGCCACCGAGATCGCCGC
GGTGCTGGTGCGCGGCGGGCAGATCGTCGGCCGCTACCAGAGCCTGATGAACAGCGGCGCCTGGGTGCCGCCGTTCATCG
AGCAGCTCACCGGCATCAGCAACCGCATGCTGGAGCGCGCGCCGCCGGCCGAGCGGGTGATGCGCGAGGTGCTCGACTTC
ACCGCCGGCTGCCCGCTGGTGGCGCACAACGCGGCCTTCGACCGCGGTTTCTGGCAGGCCGAGCGCGCCCGCGCCGGCTG
TGACGAGGACGCCGCCCACGCGTTCGCCTGCACGCTGTTGCTGGCGCGCCGCCTCTACCCCGAAGCGCCGAACCACCGGC
TGGGCACGCTCGCGAAGCTGCATGCGCTCCCCGACGGCGGCCGCGCCCACCGCGCGCTGGCCGATGCCGAGACCGCCGCC
CACCTTTTGCTGCGCATGCAGGACGACCTGCGCGTCCGCTTTGCCGCCGAGCTAGCCGAGCGTGCGGTGAGTCATGCGCT
GCTGGCCCGCCTGCAGCGAGCGCAGCGCAGCGGCCTGCGGCGCTGCCTGGCCGAGGCCGGCCTGTGA

Upstream 100 bases:

>100_bases
CCGCGCGCCGGCGCTGTAGGAGGAAGGCGCGTGCCGCCGACGGACGGCGGCGCTGGCGCGGCCCCGGGCCGGTTCGGGCG
ACACTCGCGGCTGCTCCCGC

Downstream 100 bases:

>100_bases
GTCCCCGCAAGCCAGGGACTCAAGTTCCAGCGGCGGTGACCGACAACACGGCCATGGCTCCCTCCACCGCCGACACCGCG
GCCACCGTGCGCAACGAGCA

Product: DNA-directed DNA polymerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 208; Mature: 208

Protein sequence:

>208_residues
METIAVIDFETTGISPGQGARATEIAAVLVRGGQIVGRYQSLMNSGAWVPPFIEQLTGISNRMLERAPPAERVMREVLDF
TAGCPLVAHNAAFDRGFWQAERARAGCDEDAAHAFACTLLLARRLYPEAPNHRLGTLAKLHALPDGGRAHRALADAETAA
HLLLRMQDDLRVRFAAELAERAVSHALLARLQRAQRSGLRRCLAEAGL

Sequences:

>Translated_208_residues
METIAVIDFETTGISPGQGARATEIAAVLVRGGQIVGRYQSLMNSGAWVPPFIEQLTGISNRMLERAPPAERVMREVLDF
TAGCPLVAHNAAFDRGFWQAERARAGCDEDAAHAFACTLLLARRLYPEAPNHRLGTLAKLHALPDGGRAHRALADAETAA
HLLLRMQDDLRVRFAAELAERAVSHALLARLQRAQRSGLRRCLAEAGL
>Mature_208_residues
METIAVIDFETTGISPGQGARATEIAAVLVRGGQIVGRYQSLMNSGAWVPPFIEQLTGISNRMLERAPPAERVMREVLDF
TAGCPLVAHNAAFDRGFWQAERARAGCDEDAAHAFACTLLLARRLYPEAPNHRLGTLAKLHALPDGGRAHRALADAETAA
HLLLRMQDDLRVRFAAELAERAVSHALLARLQRAQRSGLRRCLAEAGL

Specific function: Probable helicase involved in DNA repair and perhaps also replication [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR006054
- InterPro:   IPR006310
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR014013
- InterPro:   IPR006555
- InterPro:   IPR001650
- InterPro:   IPR006935
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T; PF04851 ResIII [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 22623; Mature: 22623

Theoretical pI: Translated: 8.36; Mature: 8.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METIAVIDFETTGISPGQGARATEIAAVLVRGGQIVGRYQSLMNSGAWVPPFIEQLTGIS
CCEEEEEEEECCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHH
NRMLERAPPAERVMREVLDFTAGCPLVAHNAAFDRGFWQAERARAGCDEDAAHAFACTLL
HHHHHCCCCHHHHHHHHHHHHCCCCHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
LARRLYPEAPNHRLGTLAKLHALPDGGRAHRALADAETAAHLLLRMQDDLRVRFAAELAE
HHHHHCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAVSHALLARLQRAQRSGLRRCLAEAGL
HHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
METIAVIDFETTGISPGQGARATEIAAVLVRGGQIVGRYQSLMNSGAWVPPFIEQLTGIS
CCEEEEEEEECCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHH
NRMLERAPPAERVMREVLDFTAGCPLVAHNAAFDRGFWQAERARAGCDEDAAHAFACTLL
HHHHHCCCCHHHHHHHHHHHHCCCCHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
LARRLYPEAPNHRLGTLAKLHALPDGGRAHRALADAETAAHLLLRMQDDLRVRFAAELAE
HHHHHCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAVSHALLARLQRAQRSGLRRCLAEAGL
HHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]