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The map label for this gene is fliA [H]

Identifier: 124265243

GI number: 124265243

Start: 47465

End: 48262

Strand: Direct

Name: fliA [H]

Synonym: Mpe_A0050

Alternate gene names: 124265243

Gene position: 47465-48262 (Clockwise)

Preceding gene: 124265242

Following gene: 124265244

Centisome position: 1.17

GC content: 72.81

Gene sequence:

>798_bases
GTGAGTCCCCGCAAGCCAGGGACTCAAGTTCCAGCGGCGGTGACCGACAACACGGCCATGGCTCCCTCCACCGCCGACAC
CGCGGCCACCGTGCGCAACGAGCAGTTGCACCAGCACGGCGCGCTGGTGCGCCGCATCGCCAAGCGCATGCGCGCGCGGC
TGCCGGCCAACGTGGAGATGGACGAGCTGTTGCAGGCCGGCCTGATCGGCCTGAACGAGGCGATCACCCGCTTCGAGGAA
AGCTTCGGCGCCAGCTTCGACACCTATGCCTCGCGCCGCATCGAAGGCGCCATGCTCGACAGCCTGCGCGCCGCCGACAC
CCTGTCGCGCGACGCCCGTGCCCACCAGCGCGCCATCCGCGCCGCGGTGCAGGCGCTCGAGCACCGCCTGCTGCGCCCGC
CGCGCGCGATGGAAGTGGCCAGCGAGCTCGGCTGGTCGCTGGCGCGCCTGCACCAGCGCCTGGTGGAGGCCGGCGCCGCC
GGCCAACGCGCCGGCGACGCGCCGCTCGACGGCCTGGCTGACGAGGCCTCGGCCCGCGGCGCCGAGGACGACCTGCACGC
CACCGCCGACGACCACGCCGACCCGCTGGCCGCCCTGCAGCGCCGCCAGCGCACGACAGCCCTCAACGCGGCGTTCGACA
CGCTCGAAGAGCGCGAGCAGCTGATGATGAAGATGATCTACGAGCGCGGCCTGGACCACCAGGACGCCGCCGAGTCGCTG
GGCGTCAGCCCCTCGCGCGTGTCGCAGATGCACGCGGTGGTGGTGCAGAAGCTCAAGCGGCGGTTGAAGGACTGGTAG

Upstream 100 bases:

>100_bases
CCGCCGAGCTAGCCGAGCGTGCGGTGAGTCATGCGCTGCTGGCCCGCCTGCAGCGAGCGCAGCGCAGCGGCCTGCGGCGC
TGCCTGGCCGAGGCCGGCCT

Downstream 100 bases:

>100_bases
AGCCCTGCCGCGCGACGCGCGCCGCGCCGCATCAGGCCTTGCGCAGCCTCCGCCCCACCCAGCGCGAGCGGCACAAGGCG
ACGAACTCCACCGCCCCCCA

Product: RNA polymerase sigma factor for flagellar operon

Products: NA

Alternate protein names: Sigma-28; Sigma-F factor [H]

Number of amino acids: Translated: 265; Mature: 264

Protein sequence:

>265_residues
MSPRKPGTQVPAAVTDNTAMAPSTADTAATVRNEQLHQHGALVRRIAKRMRARLPANVEMDELLQAGLIGLNEAITRFEE
SFGASFDTYASRRIEGAMLDSLRAADTLSRDARAHQRAIRAAVQALEHRLLRPPRAMEVASELGWSLARLHQRLVEAGAA
GQRAGDAPLDGLADEASARGAEDDLHATADDHADPLAALQRRQRTTALNAAFDTLEEREQLMMKMIYERGLDHQDAAESL
GVSPSRVSQMHAVVVQKLKRRLKDW

Sequences:

>Translated_265_residues
MSPRKPGTQVPAAVTDNTAMAPSTADTAATVRNEQLHQHGALVRRIAKRMRARLPANVEMDELLQAGLIGLNEAITRFEE
SFGASFDTYASRRIEGAMLDSLRAADTLSRDARAHQRAIRAAVQALEHRLLRPPRAMEVASELGWSLARLHQRLVEAGAA
GQRAGDAPLDGLADEASARGAEDDLHATADDHADPLAALQRRQRTTALNAAFDTLEEREQLMMKMIYERGLDHQDAAESL
GVSPSRVSQMHAVVVQKLKRRLKDW
>Mature_264_residues
SPRKPGTQVPAAVTDNTAMAPSTADTAATVRNEQLHQHGALVRRIAKRMRARLPANVEMDELLQAGLIGLNEAITRFEES
FGASFDTYASRRIEGAMLDSLRAADTLSRDARAHQRAIRAAVQALEHRLLRPPRAMEVASELGWSLARLHQRLVEAGAAG
QRAGDAPLDGLADEASARGAEDDLHATADDHADPLAALQRRQRTTALNAAFDTLEEREQLMMKMIYERGLDHQDAAESLG
VSPSRVSQMHAVVVQKLKRRLKDW

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This alternative sigma factor is specific for the flagellin gene (fliC) expression [H]

COG id: COG1191

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family [H]

Homologues:

Organism=Escherichia coli, GI1788231, Length=226, Percent_Identity=37.1681415929204, Blast_Score=121, Evalue=5e-29,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR000943
- InterPro:   IPR007627
- InterPro:   IPR007624
- InterPro:   IPR007630
- InterPro:   IPR012845
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF04539 Sigma70_r3; PF04545 Sigma70_r4 [H]

EC number: NA

Molecular weight: Translated: 29075; Mature: 28944

Theoretical pI: Translated: 7.38; Mature: 7.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPRKPGTQVPAAVTDNTAMAPSTADTAATVRNEQLHQHGALVRRIAKRMRARLPANVEM
CCCCCCCCCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
DELLQAGLIGLNEAITRFEESFGASFDTYASRRIEGAMLDSLRAADTLSRDARAHQRAIR
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAVQALEHRLLRPPRAMEVASELGWSLARLHQRLVEAGAAGQRAGDAPLDGLADEASARG
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCC
AEDDLHATADDHADPLAALQRRQRTTALNAAFDTLEEREQLMMKMIYERGLDHQDAAESL
CCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
GVSPSRVSQMHAVVVQKLKRRLKDW
CCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SPRKPGTQVPAAVTDNTAMAPSTADTAATVRNEQLHQHGALVRRIAKRMRARLPANVEM
CCCCCCCCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
DELLQAGLIGLNEAITRFEESFGASFDTYASRRIEGAMLDSLRAADTLSRDARAHQRAIR
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAVQALEHRLLRPPRAMEVASELGWSLARLHQRLVEAGAAGQRAGDAPLDGLADEASARG
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCC
AEDDLHATADDHADPLAALQRRQRTTALNAAFDTLEEREQLMMKMIYERGLDHQDAAESL
CCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
GVSPSRVSQMHAVVVQKLKRRLKDW
CCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1560774; 10984043 [H]