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The map label for this gene is thrA [C]

Identifier: 124028393

GI number: 124028393

Start: 1558343

End: 1559635

Strand: Reverse

Name: thrA [C]

Synonym: Hbut_1547

Alternate gene names: 124028393

Gene position: 1559635-1558343 (Counterclockwise)

Preceding gene: 124028394

Following gene: 124028392

Centisome position: 93.55

GC content: 57.77

Gene sequence:

>1293_bases
TTGCATGGTGAGCCGTTGGTAGTTGTTGTGACGCCCTCGGTTCTCCGGGACTCTTCACGACTCATATCGCTAGTAAACAC
TGTTGAAGGTCTTATGGATAAGTATAGCCTGGTGCTGGTAGCCGGTCCGGCGTACAATGTTGAGGAGGAGTTGTGGAGGT
TTACTATTTCACCTCACCGTTACAGCTGGGAGCGCATAGTCAAAACAGTCATGTCGAGGTATGCCTCGATGGCTCGTGGC
GCTGTTACTAGTGAGAGGGAGCTAGAGATACTCCGCGGCGAGTACTCTCGTCTCTCCGACGACATGGCCCGTATCGCCTG
GACCATGGCTGTTGCCGGCGAGTCCTGGGAGCAAGCAGCAGCCCTACTCCTCTCCTACGGGTCAAAACTCTCAGCAGCCC
TTACAGCGGCAGCACTGCGAAGCAGGGGTATCGAGGCTGTATGGCTTAGCGGCAGGGAAGCCGGAATAATCGCTGTAGGT
AAGCCCCTCAACGCAGATCCGGACTACGCGGCTTCGAGTGCGTCCGTGAAGGCAAAGATAAGCATACTACTCGAGCATGG
TGTCGTGCCCGTCGTAGCTGGTGGCGTGGCTGGAAGCTCCACGGGCCGGATAATGATGCTTGGCTGGGCGGGAGAGGTGC
TCACCGGCCTAGTGCTCGGCAACTTGCTGGGAGCGAGAGAGGTTAGAGTGTTGAGAGAGCCACCCGGCATATACCCGGTT
GAGCCTCCCCAGCCTGGTGCCGAGCCTCTTAGAGCGATAGGTGTGGGCCAGGCAGTCCTCCTGGCTAGACTTGGCTTACT
AAGGCTCACGCCTAAGGCTGGCAGAAACATGGTTATGGAGGTTAAACTCGTATACATGGGCTTTACGGGTCAAGCTACGC
ATGTCACGCCTGTGGGTGGCGGGGGAGCAGTAGGCATAGTACCGGCTATTATTGGGCGGCCGGCGCCTAGCGGCGAAGAG
TACTGCGAGATAGCGAGGGTCGAGGTGCTAGGCGGGAAGACTGTTGTGGTACAGGAGCTAGGCTCGCGGCCGTTCTGCTC
CTCCAAAACCAGAGTGGTAGAGGCTGCCAGGGCGACCTTGCTCCTCCTAGCCGGTGTCAAAGCCAGCCCCGAGCAGCTCG
GGCTTAAGGCTACAGCAGCACTACCAGCAAGCGATGATTCATACTTGGTTGTTGTAGAAGAGCAAAATATTGAGGACATA
GCCTTGGGAATCCATGCTAGGCTCCGGGAGGGTAACACCCCGCTATACACGGAGCCGCAGCCCCAAGCCCCAGCAAGGGC
CTGGAATACCTAG

Upstream 100 bases:

>100_bases
TTTGCTACGCCACTCCAAGACGGGAGGGGTGGCGAGGGAGGAGGCACATAGCACCTCTTGACCCCCTCCCAGCCTTCTAC
CCTATCCGGGGCCGGCCTGG

Downstream 100 bases:

>100_bases
GATAGGGACGCTGCTTGACGAAATTCGACCTGCCACCGCCGCCGCCCGGAATAGAATCGAAGAGCAACGAGGAGATAGTT
GAGGCTTTCCTTGCAGCCCT

Product: hypothetical protein

Products: ADP; 4-phospho-L-aspartate

Alternate protein names: NA

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MHGEPLVVVVTPSVLRDSSRLISLVNTVEGLMDKYSLVLVAGPAYNVEEELWRFTISPHRYSWERIVKTVMSRYASMARG
AVTSERELEILRGEYSRLSDDMARIAWTMAVAGESWEQAAALLLSYGSKLSAALTAAALRSRGIEAVWLSGREAGIIAVG
KPLNADPDYAASSASVKAKISILLEHGVVPVVAGGVAGSSTGRIMMLGWAGEVLTGLVLGNLLGAREVRVLREPPGIYPV
EPPQPGAEPLRAIGVGQAVLLARLGLLRLTPKAGRNMVMEVKLVYMGFTGQATHVTPVGGGGAVGIVPAIIGRPAPSGEE
YCEIARVEVLGGKTVVVQELGSRPFCSSKTRVVEAARATLLLLAGVKASPEQLGLKATAALPASDDSYLVVVEEQNIEDI
ALGIHARLREGNTPLYTEPQPQAPARAWNT

Sequences:

>Translated_430_residues
MHGEPLVVVVTPSVLRDSSRLISLVNTVEGLMDKYSLVLVAGPAYNVEEELWRFTISPHRYSWERIVKTVMSRYASMARG
AVTSERELEILRGEYSRLSDDMARIAWTMAVAGESWEQAAALLLSYGSKLSAALTAAALRSRGIEAVWLSGREAGIIAVG
KPLNADPDYAASSASVKAKISILLEHGVVPVVAGGVAGSSTGRIMMLGWAGEVLTGLVLGNLLGAREVRVLREPPGIYPV
EPPQPGAEPLRAIGVGQAVLLARLGLLRLTPKAGRNMVMEVKLVYMGFTGQATHVTPVGGGGAVGIVPAIIGRPAPSGEE
YCEIARVEVLGGKTVVVQELGSRPFCSSKTRVVEAARATLLLLAGVKASPEQLGLKATAALPASDDSYLVVVEEQNIEDI
ALGIHARLREGNTPLYTEPQPQAPARAWNT
>Mature_430_residues
MHGEPLVVVVTPSVLRDSSRLISLVNTVEGLMDKYSLVLVAGPAYNVEEELWRFTISPHRYSWERIVKTVMSRYASMARG
AVTSERELEILRGEYSRLSDDMARIAWTMAVAGESWEQAAALLLSYGSKLSAALTAAALRSRGIEAVWLSGREAGIIAVG
KPLNADPDYAASSASVKAKISILLEHGVVPVVAGGVAGSSTGRIMMLGWAGEVLTGLVLGNLLGAREVRVLREPPGIYPV
EPPQPGAEPLRAIGVGQAVLLARLGLLRLTPKAGRNMVMEVKLVYMGFTGQATHVTPVGGGGAVGIVPAIIGRPAPSGEE
YCEIARVEVLGGKTVVVQELGSRPFCSSKTRVVEAARATLLLLAGVKASPEQLGLKATAALPASDDSYLVVVEEQNIEDI
ALGIHARLREGNTPLYTEPQPQAPARAWNT

Specific function: Catalyzes 2 nonconsecutive reactions in the common biosynthetic pathway leading from Asp to diaminopimelate and Lys, to Met, and to Thr and Ile. [C]

COG id: COG0527

COG function: function code E; Aspartokinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.7.2.4

Molecular weight: Translated: 45577; Mature: 45577

Theoretical pI: Translated: 7.61; Mature: 7.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHGEPLVVVVTPSVLRDSSRLISLVNTVEGLMDKYSLVLVAGPAYNVEEELWRFTISPHR
CCCCCEEEEECHHHHHCHHHHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHEEECCCCC
YSWERIVKTVMSRYASMARGAVTSERELEILRGEYSRLSDDMARIAWTMAVAGESWEQAA
CCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
ALLLSYGSKLSAALTAAALRSRGIEAVWLSGREAGIIAVGKPLNADPDYAASSASVKAKI
HHHHHHCCHHHHHHHHHHHHHCCCEEEEECCCCCCEEEECCCCCCCCCCCCCCCCEEEEE
SILLEHGVVPVVAGGVAGSSTGRIMMLGWAGEVLTGLVLGNLLGAREVRVLREPPGIYPV
EEEEECCCEEEEECCCCCCCCCEEEEEECCHHHHHHHHHHHHHCHHHHHEEECCCCCCCC
EPPQPGAEPLRAIGVGQAVLLARLGLLRLTPKAGRNMVMEVKLVYMGFTGQATHVTPVGG
CCCCCCHHHHHHHCCCHHHHHHHHHHHEECCCCCCCEEEEEEEEEEECCCCCCEEEECCC
GGAVGIVPAIIGRPAPSGEEYCEIARVEVLGGKTVVVQELGSRPFCSSKTRVVEAARATL
CCCHHHHHHHHCCCCCCCHHHHHEEEEEEECCCEEEEEHHCCCCCCCCCHHHHHHHHHHE
LLLAGVKASPEQLGLKATAALPASDDSYLVVVEEQNIEDIALGIHARLREGNTPLYTEPQ
EEEECCCCCHHHCCCEEEEECCCCCCCEEEEEECCCCCCHHHHHHHEEECCCCCCCCCCC
PQAPARAWNT
CCCCCCCCCC
>Mature Secondary Structure
MHGEPLVVVVTPSVLRDSSRLISLVNTVEGLMDKYSLVLVAGPAYNVEEELWRFTISPHR
CCCCCEEEEECHHHHHCHHHHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHEEECCCCC
YSWERIVKTVMSRYASMARGAVTSERELEILRGEYSRLSDDMARIAWTMAVAGESWEQAA
CCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
ALLLSYGSKLSAALTAAALRSRGIEAVWLSGREAGIIAVGKPLNADPDYAASSASVKAKI
HHHHHHCCHHHHHHHHHHHHHCCCEEEEECCCCCCEEEECCCCCCCCCCCCCCCCEEEEE
SILLEHGVVPVVAGGVAGSSTGRIMMLGWAGEVLTGLVLGNLLGAREVRVLREPPGIYPV
EEEEECCCEEEEECCCCCCCCCEEEEEECCHHHHHHHHHHHHHCHHHHHEEECCCCCCCC
EPPQPGAEPLRAIGVGQAVLLARLGLLRLTPKAGRNMVMEVKLVYMGFTGQATHVTPVGG
CCCCCCHHHHHHHCCCHHHHHHHHHHHEECCCCCCCEEEEEEEEEEECCCCCCEEEECCC
GGAVGIVPAIIGRPAPSGEEYCEIARVEVLGGKTVVVQELGSRPFCSSKTRVVEAARATL
CCCHHHHHHHHCCCCCCCHHHHHEEEEEEECCCEEEEEHHCCCCCCCCCHHHHHHHHHHE
LLLAGVKASPEQLGLKATAALPASDDSYLVVVEEQNIEDIALGIHARLREGNTPLYTEPQ
EEEECCCCCHHHCCCEEEEECCCCCCCEEEEEECCCCCCHHHHHHHEEECCCCCCCCCCC
PQAPARAWNT
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: K+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-aspartate

Specific reaction: ATP + L-aspartate = ADP + 4-phospho-L-aspartate

General reaction: Redox reaction [C]

Inhibitor: Tris [C]

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA