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The map label for this gene is ycgM [C]

Identifier: 124027117

GI number: 124027117

Start: 206005

End: 207021

Strand: Direct

Name: ycgM [C]

Synonym: Hbut_0220

Alternate gene names: 124027117

Gene position: 206005-207021 (Clockwise)

Preceding gene: 124027112

Following gene: 124027120

Centisome position: 12.36

GC content: 60.47

Gene sequence:

>1017_bases
TTGGTGTTACTTGCCAGGTTTAGGGCTAGCCATTGGCGGCGTAGGGCTAGGCTGAACATGGTATCATCGGCCTCCCTTAT
CTGGGTGCCCTGGCTCGTGGCTATCAGCGGGCCGGGCTTTACTGTTGAGGCTGTGCTGGGGCTTGGTAGGGCAGTTCTGC
CTGGCGGTGTGGCTGAGCCTGTGCTGGTTTATCGCGGGAGGGTATATGGGCTAGGCGAGTGGGGCTATAGTGACGTCAGG
GAGGTTATGCTTGAGGTTGGCCCTGAGGAGCTTGAGGGCCTCGCACGCGTGGTCTCCTCGAGCGATAGGGGCTTGCCGCT
GAGCGCTGTCCGGCTCCTGGCCCCAGTGGATAAGCCGGAGAAGATTATCTGTATCGGCGTAAACTACCGGGCTCATGCGA
GGGAGAGTGGTGTCGAGCTGCCGGGAACCCCTAACCTATTCGTCAAGACCGGCAACAGCATTGTGGGCCCCGGCGACCCC
GTGGTGGTGCACTCTGTTGGCTTGAAGCTTGACGGGGAGGTTGAGCTAGCAGCGGTTATAGGTATACCTGCCCGCAGTAT
ACCTCCAAGCGAGGCCCCTGACGTGGTATGGGGCTTCATGGTGCTTAACGATGTGACTTCCAGGCTTGAGCAGAGGGAGC
TGGGTATAAGCCAGTGGTGGAGGGCTAAGAGCCACGACACCTACGCCCCCACCGGCCCGATAATCGTGCCACGCCACATG
GTTAGCATCGGCGACACTGAGCTAGAGCTCGTGGTTGATGGTATCGTGGCGAGACGTGGCAACACGGGCGACATGGTTCA
TAGCGTCTGGGACATAGTTTCAGTAGCTAGCACGTCAGCCCTACTCGTGCCGGGCGACATAATCTGCACTGGAACGCCTG
CCGGAACGATGCCGGACGGAAAACCGGCGAAGACCCCGGAGCCGGGCTCCGTTATGAGGGCGTGCGCCCGGGGGATAGGC
TGTATCGAGAACAGAGTGGTTCTCGACGAGGAGCTATGCCCTCATGGCGGCCTCTAG

Upstream 100 bases:

>100_bases
ATGCGTCTTTTCGTCCCTGGTTTAGGCTTCATACGTGAGTGCACGGGATACGTTGGGGGGCTTGGGGCTCAGCTAGTTGT
TATGCCTCCAGTTTACAGTC

Downstream 100 bases:

>100_bases
CCGGGCCTTAATCTTCGGCATGAGTCTCCGTGTCTTCCACTTTATGTAGGCTATGACGGCTTTAAGCCCGAGTTTTAGCG
GTATGTACTCGACGCCCCGC

Product: fumarylacetoacetate (FAA) hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MVLLARFRASHWRRRARLNMVSSASLIWVPWLVAISGPGFTVEAVLGLGRAVLPGGVAEPVLVYRGRVYGLGEWGYSDVR
EVMLEVGPEELEGLARVVSSSDRGLPLSAVRLLAPVDKPEKIICIGVNYRAHARESGVELPGTPNLFVKTGNSIVGPGDP
VVVHSVGLKLDGEVELAAVIGIPARSIPPSEAPDVVWGFMVLNDVTSRLEQRELGISQWWRAKSHDTYAPTGPIIVPRHM
VSIGDTELELVVDGIVARRGNTGDMVHSVWDIVSVASTSALLVPGDIICTGTPAGTMPDGKPAKTPEPGSVMRACARGIG
CIENRVVLDEELCPHGGL

Sequences:

>Translated_338_residues
MVLLARFRASHWRRRARLNMVSSASLIWVPWLVAISGPGFTVEAVLGLGRAVLPGGVAEPVLVYRGRVYGLGEWGYSDVR
EVMLEVGPEELEGLARVVSSSDRGLPLSAVRLLAPVDKPEKIICIGVNYRAHARESGVELPGTPNLFVKTGNSIVGPGDP
VVVHSVGLKLDGEVELAAVIGIPARSIPPSEAPDVVWGFMVLNDVTSRLEQRELGISQWWRAKSHDTYAPTGPIIVPRHM
VSIGDTELELVVDGIVARRGNTGDMVHSVWDIVSVASTSALLVPGDIICTGTPAGTMPDGKPAKTPEPGSVMRACARGIG
CIENRVVLDEELCPHGGL
>Mature_338_residues
MVLLARFRASHWRRRARLNMVSSASLIWVPWLVAISGPGFTVEAVLGLGRAVLPGGVAEPVLVYRGRVYGLGEWGYSDVR
EVMLEVGPEELEGLARVVSSSDRGLPLSAVRLLAPVDKPEKIICIGVNYRAHARESGVELPGTPNLFVKTGNSIVGPGDP
VVVHSVGLKLDGEVELAAVIGIPARSIPPSEAPDVVWGFMVLNDVTSRLEQRELGISQWWRAKSHDTYAPTGPIIVPRHM
VSIGDTELELVVDGIVARRGNTGDMVHSVWDIVSVASTSALLVPGDIICTGTPAGTMPDGKPAKTPEPGSVMRACARGIG
CIENRVVLDEELCPHGGL

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI156231349, Length=246, Percent_Identity=36.5853658536585, Blast_Score=145, Evalue=7e-35,
Organism=Homo sapiens, GI40786394, Length=246, Percent_Identity=35.7723577235772, Blast_Score=138, Evalue=7e-33,
Organism=Homo sapiens, GI13654274, Length=181, Percent_Identity=32.0441988950276, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI215422413, Length=181, Percent_Identity=32.0441988950276, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI66348062, Length=181, Percent_Identity=32.0441988950276, Blast_Score=90, Evalue=3e-18,
Organism=Escherichia coli, GI1787428, Length=189, Percent_Identity=31.2169312169312, Blast_Score=87, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17557057, Length=177, Percent_Identity=36.1581920903955, Blast_Score=100, Evalue=8e-22,
Organism=Saccharomyces cerevisiae, GI6324161, Length=210, Percent_Identity=31.4285714285714, Blast_Score=81, Evalue=2e-16,
Organism=Drosophila melanogaster, GI28572127, Length=239, Percent_Identity=38.0753138075314, Blast_Score=166, Evalue=2e-41,
Organism=Drosophila melanogaster, GI24663695, Length=219, Percent_Identity=34.2465753424658, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI28571789, Length=181, Percent_Identity=31.4917127071823, Blast_Score=84, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 36039; Mature: 36039

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLLARFRASHWRRRARLNMVSSASLIWVPWLVAISGPGFTVEAVLGLGRAVLPGGVAEP
CEEEEHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCEEHHHHHHCCHHHCCCCCCCC
VLVYRGRVYGLGEWGYSDVREVMLEVGPEELEGLARVVSSSDRGLPLSAVRLLAPVDKPE
EEEECCCEEEECCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCC
KIICIGVNYRAHARESGVELPGTPNLFVKTGNSIVGPGDPVVVHSVGLKLDGEVELAAVI
EEEEEECCCCHHHHHCCCCCCCCCCEEEEECCEECCCCCCEEEEEECEEECCCEEEEEEE
GIPARSIPPSEAPDVVWGFMVLNDVTSRLEQRELGISQWWRAKSHDTYAPTGPIIVPRHM
ECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCEEECCCE
VSIGDTELELVVDGIVARRGNTGDMVHSVWDIVSVASTSALLVPGDIICTGTPAGTMPDG
EECCCCHHHHEEHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEECCCEEECCCCCCCCCCC
KPAKTPEPGSVMRACARGIGCIENRVVLDEELCPHGGL
CCCCCCCCHHHHHHHHHCCCHHCCCEEECHHCCCCCCC
>Mature Secondary Structure
MVLLARFRASHWRRRARLNMVSSASLIWVPWLVAISGPGFTVEAVLGLGRAVLPGGVAEP
CEEEEHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCEEHHHHHHCCHHHCCCCCCCC
VLVYRGRVYGLGEWGYSDVREVMLEVGPEELEGLARVVSSSDRGLPLSAVRLLAPVDKPE
EEEECCCEEEECCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCC
KIICIGVNYRAHARESGVELPGTPNLFVKTGNSIVGPGDPVVVHSVGLKLDGEVELAAVI
EEEEEECCCCHHHHHCCCCCCCCCCEEEEECCEECCCCCCEEEEEECEEECCCEEEEEEE
GIPARSIPPSEAPDVVWGFMVLNDVTSRLEQRELGISQWWRAKSHDTYAPTGPIIVPRHM
ECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCEEECCCE
VSIGDTELELVVDGIVARRGNTGDMVHSVWDIVSVASTSALLVPGDIICTGTPAGTMPDG
EECCCCHHHHEEHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEECCCEEECCCCCCCCCCC
KPAKTPEPGSVMRACARGIGCIENRVVLDEELCPHGGL
CCCCCCCCHHHHHHHHHCCCHHCCCEEECHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]