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The map label for this gene is mhpC [H]

Identifier: 124026309

GI number: 124026309

Start: 1310919

End: 1311890

Strand: Direct

Name: mhpC [H]

Synonym: NATL1_16031

Alternate gene names: 124026309

Gene position: 1310919-1311890 (Clockwise)

Preceding gene: 124026304

Following gene: 124026310

Centisome position: 70.3

GC content: 33.33

Gene sequence:

>972_bases
ATGCAGCAAAATATTCTTAATAAAGAACCTTTAATGGGATCTCCTCATTGGGGTGAGTCTAAGTATTGGAGCTACAAAGA
TCTTAGTGTTCACTTCAGAGTGACTGGAGAGGAATCTAATCCTCCCATTGTTCTAATTCATGGGTTTGGAGCTAGCAGCG
ATCACTGGAGAAATAATGCAGAAATATTTGCATCAGAAGGTTTTAGGGTCTTCGGAATAGATTTAATAGGTTTTGGAAAA
TCAGAGCAAAATCTTCAAAGTAAAATAAAGCATTTAGAGAATCAATTTTGGGCAAATCAATTAGCTTCATTTCTTGATGA
AATTGTTGACATTCAAAAGAACGGAAAAGTTATATTAATTGGAAATTCATTGGGAGCTTTAACAGCAATCACAACTCTCT
CTAATAGACCAGAGTTAATAAAAACAATAATTGCAGCACCACTACCAGAGCCAGTTTTTGTTAATCCAATTAAATTTTCT
TTTCCAAATTGGCTTTTAAAAGTTAAAAGTTTTCTGATAAAAATTGTTTTTCATTTATTTCCACTGAAGACATTAGTAAA
TTTGATATCAAGAACAAAATTAATTACTTTTGCTCTTCAAAGCGCCTATTTTCGCTCAATTTTAAATGATACTCCTCTAA
AAAGGATAGTTACAGTCCCAGCCAAGAGAGTGAATGCATCCAAAGCTCTAAGAGCTATGTGCATTGGAATGAGCAATAGA
CCAAATTCGGCAAAAGGTCCATCTATTATTGAGAAGATTCAAAACCTGTCAAATCGTCCCCCAATTTTATTAATTTGGGG
AAAACAGGATAAATTGATACCTATATTTTTAGCAAAAAAACTACTAAAGCTCCATCCTTGGCTTAAATTAACCGTAGTTA
ACGAAGCAGGTCATTGTCCCCACGATGAATTACCGAAAGATTTCAATCAAATTGTTATGAAATGGCTGAAGAACTTAAAA
ACTTCTAAGTAA

Upstream 100 bases:

>100_bases
CATTCAGTCCAGAATCCAAAGGCATGAGCAAATTTTTAAAATAAACTTAAAATGAAACTACAAATGATAAAAAACAAAGT
TAAATTGATTCTTGATCTAA

Downstream 100 bases:

>100_bases
AAAATATGAAGCACACACTTTCAGTTTTAGTTGAAGATGAATCTGGAGCACTAAGCAGGATTGCAGGCCTTTTTGCAAGA
AGAGGATTTAATATTGATAG

Product: putative alpha/beta hydrolase superfamily protein

Products: 2-oxopent-4-enoate; succinate [C]

Alternate protein names: 2-hydroxy-6-ketonona-2,4-diene-1,9-dioic acid 5,6-hydrolase; 2-hydroxy-6-oxonona-2,4,7-triene-1,9-dioic acid 5,6-hydrolase; 2-hydroxy-6-oxonona-2,4-diene-1,9-dioic acid 5,6-hydrolase [H]

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MQQNILNKEPLMGSPHWGESKYWSYKDLSVHFRVTGEESNPPIVLIHGFGASSDHWRNNAEIFASEGFRVFGIDLIGFGK
SEQNLQSKIKHLENQFWANQLASFLDEIVDIQKNGKVILIGNSLGALTAITTLSNRPELIKTIIAAPLPEPVFVNPIKFS
FPNWLLKVKSFLIKIVFHLFPLKTLVNLISRTKLITFALQSAYFRSILNDTPLKRIVTVPAKRVNASKALRAMCIGMSNR
PNSAKGPSIIEKIQNLSNRPPILLIWGKQDKLIPIFLAKKLLKLHPWLKLTVVNEAGHCPHDELPKDFNQIVMKWLKNLK
TSK

Sequences:

>Translated_323_residues
MQQNILNKEPLMGSPHWGESKYWSYKDLSVHFRVTGEESNPPIVLIHGFGASSDHWRNNAEIFASEGFRVFGIDLIGFGK
SEQNLQSKIKHLENQFWANQLASFLDEIVDIQKNGKVILIGNSLGALTAITTLSNRPELIKTIIAAPLPEPVFVNPIKFS
FPNWLLKVKSFLIKIVFHLFPLKTLVNLISRTKLITFALQSAYFRSILNDTPLKRIVTVPAKRVNASKALRAMCIGMSNR
PNSAKGPSIIEKIQNLSNRPPILLIWGKQDKLIPIFLAKKLLKLHPWLKLTVVNEAGHCPHDELPKDFNQIVMKWLKNLK
TSK
>Mature_323_residues
MQQNILNKEPLMGSPHWGESKYWSYKDLSVHFRVTGEESNPPIVLIHGFGASSDHWRNNAEIFASEGFRVFGIDLIGFGK
SEQNLQSKIKHLENQFWANQLASFLDEIVDIQKNGKVILIGNSLGALTAITTLSNRPELIKTIIAAPLPEPVFVNPIKFS
FPNWLLKVKSFLIKIVFHLFPLKTLVNLISRTKLITFALQSAYFRSILNDTPLKRIVTVPAKRVNASKALRAMCIGMSNR
PNSAKGPSIIEKIQNLSNRPPILLIWGKQDKLIPIFLAKKLLKLHPWLKLTVVNEAGHCPHDELPKDFNQIVMKWLKNLK
TSK

Specific function: Catalyzes the cleavage of the C5-C6 bond of 2-hydroxy-6- oxononadienedioate and 2-hydroxy-6-oxononatrienedioate, a dienol ring fission product of the bacterial meta-cleavage pathway for degradation of phenylpropionic acid [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mhpC alpha/beta hydrolase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: 3.7.1.- [C]

Molecular weight: Translated: 36566; Mature: 36566

Theoretical pI: Translated: 10.69; Mature: 10.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQNILNKEPLMGSPHWGESKYWSYKDLSVHFRVTGEESNPPIVLIHGFGASSDHWRNNA
CCCCCCCCCCCCCCCCCCCCCCEEEECEEEEEEEECCCCCCCEEEEECCCCCCCCCCCCC
EIFASEGFRVFGIDLIGFGKSEQNLQSKIKHLENQFWANQLASFLDEIVDIQKNGKVILI
EEEECCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
GNSLGALTAITTLSNRPELIKTIIAAPLPEPVFVNPIKFSFPNWLLKVKSFLIKIVFHLF
ECCCCHHHHHHHCCCCHHHHHHHHHCCCCCCCEECCEECCCHHHHHHHHHHHHHHHHHHH
PLKTLVNLISRTKLITFALQSAYFRSILNDTPLKRIVTVPAKRVNASKALRAMCIGMSNR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHCCHHHHHHHHHHCCCCC
PNSAKGPSIIEKIQNLSNRPPILLIWGKQDKLIPIFLAKKLLKLHPWLKLTVVNEAGHCP
CCCCCCCHHHHHHHHHCCCCCEEEEECCCCCEEHHHHHHHHHHHCCCEEEEEECCCCCCC
HDELPKDFNQIVMKWLKNLKTSK
CCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQQNILNKEPLMGSPHWGESKYWSYKDLSVHFRVTGEESNPPIVLIHGFGASSDHWRNNA
CCCCCCCCCCCCCCCCCCCCCCEEEECEEEEEEEECCCCCCCEEEEECCCCCCCCCCCCC
EIFASEGFRVFGIDLIGFGKSEQNLQSKIKHLENQFWANQLASFLDEIVDIQKNGKVILI
EEEECCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
GNSLGALTAITTLSNRPELIKTIIAAPLPEPVFVNPIKFSFPNWLLKVKSFLIKIVFHLF
ECCCCHHHHHHHCCCCHHHHHHHHHCCCCCCCEECCEECCCHHHHHHHHHHHHHHHHHHH
PLKTLVNLISRTKLITFALQSAYFRSILNDTPLKRIVTVPAKRVNASKALRAMCIGMSNR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHCCHHHHHHHHHHCCCCC
PNSAKGPSIIEKIQNLSNRPPILLIWGKQDKLIPIFLAKKLLKLHPWLKLTVVNEAGHCP
CCCCCCCHHHHHHHHHCCCCCEEEEECCCCCEEHHHHHHHHHHHCCCEEEEEECCCCCCC
HDELPKDFNQIVMKWLKNLKTSK
CCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-hydroxy-6-ketononadienedicarboxylate; H2O [C]

Specific reaction: 2-hydroxy-6-ketononadienedicarboxylate + H2O = 2-oxopent-4-enoate + succinate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA