Click here to switch to the map view.

The map label for this gene is ilvH [H]

Identifier: 124026310

GI number: 124026310

Start: 1311896

End: 1312399

Strand: Direct

Name: ilvH [H]

Synonym: NATL1_16041

Alternate gene names: 124026310

Gene position: 1311896-1312399 (Clockwise)

Preceding gene: 124026309

Following gene: 124026313

Centisome position: 70.35

GC content: 38.1

Gene sequence:

>504_bases
ATGAAGCACACACTTTCAGTTTTAGTTGAAGATGAATCTGGAGCACTAAGCAGGATTGCAGGCCTTTTTGCAAGAAGAGG
ATTTAATATTGATAGCTTGGCTGTTGGTCCTGCAGAAGCAAAAGGGATATCTAGACTAACAATGGTCGTTCAAGGAGACG
AATCGACGCTTCAACAAATGACCAAACAACTAAACAAATTAATCAATGTTTTAGAAGTTCTCGATTTGACAACTTTACCA
GCTGTAGAGAGAGAGTTGATGCTCTTGAAAGTCTCTGCATCATCTGAAAACAGAGGTAAAATATTAGATCTTGTTCAAGT
TTTCAGAGCAAAAGTTGTAGATGTTTCGGATAGTGCTTTGACACTTGAAGTTGTTGGTGATCCAGGCAAACTTGTTGCTC
TGGAAAATTTATTGAAGCCTTATGGAATTTTAGAAATTGCTCGGACAGGGAAAGTTGCTCTTAAGAGGGCCTCAGGAGTA
AATACAGAAATGTTAAAAACCTAA

Upstream 100 bases:

>100_bases
TTAACGAAGCAGGTCATTGTCCCCACGATGAATTACCGAAAGATTTCAATCAAATTGTTATGAAATGGCTGAAGAACTTA
AAAACTTCTAAGTAAAAAAT

Downstream 100 bases:

>100_bases
AAAATAATATTTTTCTTCAAGAGTCAACTCTTTTAGCTTCAATTATAAAATCTTCTTCTTGAATTAAATCAACTATATTC
ATACCACTAATCACTTTTCC

Product: acetolactate synthase 3 regulatory subunit

Products: NA

Alternate protein names: Acetohydroxy-acid synthase small subunit; AHAS; ALS [H]

Number of amino acids: Translated: 167; Mature: 167

Protein sequence:

>167_residues
MKHTLSVLVEDESGALSRIAGLFARRGFNIDSLAVGPAEAKGISRLTMVVQGDESTLQQMTKQLNKLINVLEVLDLTTLP
AVERELMLLKVSASSENRGKILDLVQVFRAKVVDVSDSALTLEVVGDPGKLVALENLLKPYGILEIARTGKVALKRASGV
NTEMLKT

Sequences:

>Translated_167_residues
MKHTLSVLVEDESGALSRIAGLFARRGFNIDSLAVGPAEAKGISRLTMVVQGDESTLQQMTKQLNKLINVLEVLDLTTLP
AVERELMLLKVSASSENRGKILDLVQVFRAKVVDVSDSALTLEVVGDPGKLVALENLLKPYGILEIARTGKVALKRASGV
NTEMLKT
>Mature_167_residues
MKHTLSVLVEDESGALSRIAGLFARRGFNIDSLAVGPAEAKGISRLTMVVQGDESTLQQMTKQLNKLINVLEVLDLTTLP
AVERELMLLKVSASSENRGKILDLVQVFRAKVVDVSDSALTLEVVGDPGKLVALENLLKPYGILEIARTGKVALKRASGV
NTEMLKT

Specific function: Valine and isoleucine biosynthesis; first step. [C]

COG id: COG0440

COG function: function code E; Acetolactate synthase, small (regulatory) subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ACT domain [H]

Homologues:

Organism=Escherichia coli, GI1786266, Length=161, Percent_Identity=44.0993788819876, Blast_Score=134, Evalue=4e-33,
Organism=Saccharomyces cerevisiae, GI6319837, Length=204, Percent_Identity=31.3725490196078, Blast_Score=108, Evalue=4e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004789
- InterPro:   IPR019455
- InterPro:   IPR002912 [H]

Pfam domain/function: PF01842 ACT; PF10369 ALS_ss_C [H]

EC number: =2.2.1.6 [H]

Molecular weight: Translated: 18010; Mature: 18010

Theoretical pI: Translated: 9.02; Mature: 9.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHTLSVLVEDESGALSRIAGLFARRGFNIDSLAVGPAEAKGISRLTMVVQGDESTLQQM
CCCEEEEEEECCCCHHHHHHHHHHHCCCCCCCEEECCHHHCCCEEEEEEEECCHHHHHHH
TKQLNKLINVLEVLDLTTLPAVERELMLLKVSASSENRGKILDLVQVFRAKVVDVSDSAL
HHHHHHHHHHHHHHHHHCCCHHCCEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCEE
TLEVVGDPGKLVALENLLKPYGILEIARTGKVALKRASGVNTEMLKT
EEEEECCCCCEEHHHHHHCCCCHHHHHCCCHHHHHHCCCCCHHHHCC
>Mature Secondary Structure
MKHTLSVLVEDESGALSRIAGLFARRGFNIDSLAVGPAEAKGISRLTMVVQGDESTLQQM
CCCEEEEEEECCCCHHHHHHHHHHHCCCCCCCEEECCHHHCCCEEEEEEEECCHHHHHHH
TKQLNKLINVLEVLDLTTLPAVERELMLLKVSASSENRGKILDLVQVFRAKVVDVSDSAL
HHHHHHHHHHHHHHHHHCCCHHCCEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCEE
TLEVVGDPGKLVALENLLKPYGILEIARTGKVALKRASGVNTEMLKT
EEEEECCCCCEEHHHHHHCCCCHHHHHCCCHHHHHHCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]