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The map label for this gene is trxB [H]

Identifier: 124026304

GI number: 124026304

Start: 1307657

End: 1309033

Strand: Direct

Name: trxB [H]

Synonym: NATL1_15981

Alternate gene names: 124026304

Gene position: 1307657-1309033 (Clockwise)

Preceding gene: 124026303

Following gene: 124026309

Centisome position: 70.13

GC content: 38.42

Gene sequence:

>1377_bases
ATGCCAGCCGAAAACAAAGAATTAAAAACTGAAAATTTAGTAATTATAGGTTCAGGACCCGCTGGATATACCGCTGCTAT
CTATGCGGCAAGAGCGAATCTACAACCACTTATTATTACTGGGTTTGAAAAAGGTGGAATTCCAGGTGGTCAATTAATGA
CGACAACATTTGTAGAGAATTTCCCAGGTTTCCCAAATGGAGTTCAAGGTCCAGAATTGATGGATTTAATAAAAGCACAA
GCTGTGAGATGGGGGACAAATCTAATTGAAGAAGATGCCATATCAATTGATCTAAGCAAAAGACCCTTTTCTATTGTTAC
TACTACCAAAAAAATCAAAACAAACTCCTTAATTATTTCCACCGGAGCAAGCGCCAATCGTCTAGGCCTTAAAAATGAGA
AATTATTTTGGAGTAAGGGTATTAGTGCCTGTGCAATTTGCGATGGAGCAACACCTCAATTTAGAGATGAAGAACTTGCC
GTAATTGGAGGAGGGGACTCGGCTTGTGAAGAAGCCGAATATCTAACAAAATATGGTAGCCATGTACATTTGTTAGTCAG
ATCAAGGAAACTAAGGGCTTCAGCTGCAATGGCCGATCGAGTAGAAGCAAATCCCAATATTACGATTCATTGGGAGACAG
AGCTTTTAGATGTTTTGGGTAATGATTGGCTAGAGAAATTAAAAGTTAAAAGAAAAGACACTAACCAAGAATATGAAATT
TTAGCTAAGGGACTTTTTTATGCTATTGGACATACTCCCAACACGTCTTTATTTACCAATCAATTAAATAAAGACTCAAA
AGGTTACTTAATAACACAACCTGGAAGACCTGAAACTTCATTAGAAGGCGTTTATGCTGCAGGAGATGTTGCTGATTCGG
AATGGCGTCAAGGTGTTACTGCGGCAGGCAGCGGTTGCAAAGCAGCTTTAGCTGCTGAAAGATGGCTAACAAAAAACAAC
TTAGCAACACTTATAAAAAGGATTGAATTAGAGCCCTCAAAGGCTGAAAAAGCAAAAACTTTAGAAATTAGTAACGAGGC
AAATTTCGACCCCGACAAGACATGGCAAAAGGGAAGTTATGCACTAAGAAAGTTGTATCATGAGACAGAAAAACCTCTCT
TCGTAGTTTACACATCCAGTAGCTGCGGGCCTTGTCACATTCTCAAGCCCCAACTTCTCAGAGTTCTTAACGAGTCAAAA
GGGAAAGCTATAGGTGTTGAAATTGATATTGAAAACGACCAAGATATTGCCAAGCAAGCTGAAGTAAGCGGGACTCCAAC
AGTACATCTTTTTAAGAATAAGGAATTAAAAAAACAATGGAAAGGTGTTAAAACAAGAAGTGCATATAAAGCCGCATTAG
ATGAACTAATTAATTAA

Upstream 100 bases:

>100_bases
AATAAATTTGAGATTAAAAAATAATCCAAGTTATTAATGCTTTAAATACACTTTCACGATTTTTTCTTATATCGTATAAC
TCAGTTTGATTTGGTATTGC

Downstream 100 bases:

>100_bases
CGATATAAGGTCTATTTTTTCCTGGGCCCTCCTGGTCTATTGCCACCTTGCCTTCCTCCTCCAGGCCCTACGTTTCTTTC
TCTATATGTAATACGACCAC

Product: putative thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 458; Mature: 457

Protein sequence:

>458_residues
MPAENKELKTENLVIIGSGPAGYTAAIYAARANLQPLIITGFEKGGIPGGQLMTTTFVENFPGFPNGVQGPELMDLIKAQ
AVRWGTNLIEEDAISIDLSKRPFSIVTTTKKIKTNSLIISTGASANRLGLKNEKLFWSKGISACAICDGATPQFRDEELA
VIGGGDSACEEAEYLTKYGSHVHLLVRSRKLRASAAMADRVEANPNITIHWETELLDVLGNDWLEKLKVKRKDTNQEYEI
LAKGLFYAIGHTPNTSLFTNQLNKDSKGYLITQPGRPETSLEGVYAAGDVADSEWRQGVTAAGSGCKAALAAERWLTKNN
LATLIKRIELEPSKAEKAKTLEISNEANFDPDKTWQKGSYALRKLYHETEKPLFVVYTSSSCGPCHILKPQLLRVLNESK
GKAIGVEIDIENDQDIAKQAEVSGTPTVHLFKNKELKKQWKGVKTRSAYKAALDELIN

Sequences:

>Translated_458_residues
MPAENKELKTENLVIIGSGPAGYTAAIYAARANLQPLIITGFEKGGIPGGQLMTTTFVENFPGFPNGVQGPELMDLIKAQ
AVRWGTNLIEEDAISIDLSKRPFSIVTTTKKIKTNSLIISTGASANRLGLKNEKLFWSKGISACAICDGATPQFRDEELA
VIGGGDSACEEAEYLTKYGSHVHLLVRSRKLRASAAMADRVEANPNITIHWETELLDVLGNDWLEKLKVKRKDTNQEYEI
LAKGLFYAIGHTPNTSLFTNQLNKDSKGYLITQPGRPETSLEGVYAAGDVADSEWRQGVTAAGSGCKAALAAERWLTKNN
LATLIKRIELEPSKAEKAKTLEISNEANFDPDKTWQKGSYALRKLYHETEKPLFVVYTSSSCGPCHILKPQLLRVLNESK
GKAIGVEIDIENDQDIAKQAEVSGTPTVHLFKNKELKKQWKGVKTRSAYKAALDELIN
>Mature_457_residues
PAENKELKTENLVIIGSGPAGYTAAIYAARANLQPLIITGFEKGGIPGGQLMTTTFVENFPGFPNGVQGPELMDLIKAQA
VRWGTNLIEEDAISIDLSKRPFSIVTTTKKIKTNSLIISTGASANRLGLKNEKLFWSKGISACAICDGATPQFRDEELAV
IGGGDSACEEAEYLTKYGSHVHLLVRSRKLRASAAMADRVEANPNITIHWETELLDVLGNDWLEKLKVKRKDTNQEYEIL
AKGLFYAIGHTPNTSLFTNQLNKDSKGYLITQPGRPETSLEGVYAAGDVADSEWRQGVTAAGSGCKAALAAERWLTKNNL
ATLIKRIELEPSKAEKAKTLEISNEANFDPDKTWQKGSYALRKLYHETEKPLFVVYTSSSCGPCHILKPQLLRVLNESKG
KAIGVEIDIENDQDIAKQAEVSGTPTVHLFKNKELKKQWKGVKTRSAYKAALDELIN

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=319, Percent_Identity=47.0219435736677, Blast_Score=261, Evalue=4e-71,
Organism=Escherichia coli, GI87081763, Length=317, Percent_Identity=29.6529968454259, Blast_Score=115, Evalue=5e-27,
Organism=Saccharomyces cerevisiae, GI6320560, Length=311, Percent_Identity=51.4469453376206, Blast_Score=323, Evalue=3e-89,
Organism=Saccharomyces cerevisiae, GI6321898, Length=311, Percent_Identity=50.4823151125402, Blast_Score=320, Evalue=2e-88,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 50222; Mature: 50091

Theoretical pI: Translated: 8.11; Mature: 8.11

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAENKELKTENLVIIGSGPAGYTAAIYAARANLQPLIITGFEKGGIPGGQLMTTTFVEN
CCCCCCCCCCCCEEEEECCCCCCEEEEEEECCCCCEEEEECCCCCCCCCCCEEEHHHHHH
FPGFPNGVQGPELMDLIKAQAVRWGTNLIEEDAISIDLSKRPFSIVTTTKKIKTNSLIIS
CCCCCCCCCCHHHHHHHHHHHHHHCCHHHHCCCEEEEECCCCEEEEEECEEEEECEEEEE
TGASANRLGLKNEKLFWSKGISACAICDGATPQFRDEELAVIGGGDSACEEAEYLTKYGS
CCCCCCCCCCCCCCEEHHCCCCEEEEECCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCC
HVHLLVRSRKLRASAAMADRVEANPNITIHWETELLDVLGNDWLEKLKVKRKDTNQEYEI
EEEEEEECHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
LAKGLFYAIGHTPNTSLFTNQLNKDSKGYLITQPGRPETSLEGVYAAGDVADSEWRQGVT
HHHHHHEEECCCCCCCHHHHHCCCCCCCEEEECCCCCCCCCCCEEEECCCCCHHHHCCCC
AAGSGCKAALAAERWLTKNNLATLIKRIELEPSKAEKAKTLEISNEANFDPDKTWQKGSY
CCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCHHCCCEEEEECCCCCCCCCCCCCHHHH
ALRKLYHETEKPLFVVYTSSSCGPCHILKPQLLRVLNESKGKAIGVEIDIENDQDIAKQA
HHHHHHHHCCCCEEEEEECCCCCCEECCHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHH
EVSGTPTVHLFKNKELKKQWKGVKTRSAYKAALDELIN
HCCCCCEEEEECCCHHHHHHCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
PAENKELKTENLVIIGSGPAGYTAAIYAARANLQPLIITGFEKGGIPGGQLMTTTFVEN
CCCCCCCCCCCEEEEECCCCCCEEEEEEECCCCCEEEEECCCCCCCCCCCEEEHHHHHH
FPGFPNGVQGPELMDLIKAQAVRWGTNLIEEDAISIDLSKRPFSIVTTTKKIKTNSLIIS
CCCCCCCCCCHHHHHHHHHHHHHHCCHHHHCCCEEEEECCCCEEEEEECEEEEECEEEEE
TGASANRLGLKNEKLFWSKGISACAICDGATPQFRDEELAVIGGGDSACEEAEYLTKYGS
CCCCCCCCCCCCCCEEHHCCCCEEEEECCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCC
HVHLLVRSRKLRASAAMADRVEANPNITIHWETELLDVLGNDWLEKLKVKRKDTNQEYEI
EEEEEEECHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
LAKGLFYAIGHTPNTSLFTNQLNKDSKGYLITQPGRPETSLEGVYAAGDVADSEWRQGVT
HHHHHHEEECCCCCCCHHHHHCCCCCCCEEEECCCCCCCCCCCEEEECCCCCHHHHCCCC
AAGSGCKAALAAERWLTKNNLATLIKRIELEPSKAEKAKTLEISNEANFDPDKTWQKGSY
CCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCHHCCCEEEEECCCCCCCCCCCCCHHHH
ALRKLYHETEKPLFVVYTSSSCGPCHILKPQLLRVLNESKGKAIGVEIDIENDQDIAKQA
HHHHHHHHCCCCEEEEEECCCCCCEECCHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHH
EVSGTPTVHLFKNKELKKQWKGVKTRSAYKAALDELIN
HCCCCCEEEEECCCHHHHHHCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]