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The map label for this gene is menC [H]

Identifier: 124024963

GI number: 124024963

Start: 230829

End: 231800

Strand: Reverse

Name: menC [H]

Synonym: NATL1_02501

Alternate gene names: 124024963

Gene position: 231800-230829 (Counterclockwise)

Preceding gene: 124024964

Following gene: 124024962

Centisome position: 12.43

GC content: 35.6

Gene sequence:

>972_bases
ATGAAATTAATAATTAATATCAAGCCATTTTCATTTCAACTAACAAGAAAGTTAATAACCTCGCAAGGAATTATTCATAA
CAAGGTAGGTTTATTGTTGCAAATAAAAGACTCAAATGGAAATTACGGATGGGGGGAAGTTTCACCTATTGAGAAAAAGG
AATTAGAAAAAAGTATCGAAAGTCTTGATTTTATTGGGAAACAAACTACAAAAGATTCAATAGAAAATTATTTATTTGAA
TTGCCAGGCGCACTTGCTTTCGGATTAGGGTCCTGCTTAGCCGATTTAGAAAGTCTCACTCAAAGGAAGTTAAATCTTGA
AGGTTTTGACGTCGCAAAATCAGCTTATCTTTTACCTACAGATATTGATCCATTAGAGTCAATACGTAAATATGTAGATG
AATCAAATGAGAAGAAAAGTTCTTGTACAATAAAATGGAAAGTATCTCACCTAGAAAATAACTTTAAGGAAGAAAAAACA
TTACAAAAAATCTTAGACATTTTACCAAATAATTTTAAACTTAGAATTGATCCAAATGGAGGTTGGAGTCGCCAAAAAGC
ACAAGAATGGAGTAACGAACTCAAAAACGAACCTCGTTTGGAATGGATTGAACAGCCACTCCCATCAAAAGATATTGAAG
GTTTATTTTCATTGGCCACTCAAATTCCAATCGCACTAGATGAATCTTTGGTTGAATTTCCATATTTACGAAAAACATGG
AAAAGTTGGCAAATACGTCGCCCTGCATTAGATGGTGATCCGAGATTACTGTTAAAAGAAATAGAACAAGAAGATAGTCA
AACAGTCATAAGCACAGCTTTTGAAACTGGTATTGGGAGAAGGTGGGTTAATCACCTCGCTGCCAGACAAGTCAAAGGGG
GAAATCCTTGTTCACCTGGACTTGCACCTGGATGGTGCCCAAAAGGCCCACTCTTCAACAACAATCCGAAATTAGTCTGG
GAAGCCGTATGA

Upstream 100 bases:

>100_bases
TTTTTAGCTTTACGCTTTCAGACAATTAATGGTTTATGCTTGAGTATAGGTTTTGCTATATCCTCATTTTTTTATAATTA
ATTTTTGATTTTATTGAATC

Downstream 100 bases:

>100_bases
CCAAAATTGCAGTTGTAGAGTGTATTCCTGAAAAAAACCTGGACTGTTCAAAAGAAATTTTGAAGAATTTTGAAAAGCAT
AACTGGGTATATCTAGCGCC

Product: putative O-succinylbenzoate synthase

Products: NA

Alternate protein names: OSB synthase; OSBS; 4-(2'-carboxyphenyl)-4-oxybutyric acid synthase; o-succinylbenzoic acid synthase [H]

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MKLIINIKPFSFQLTRKLITSQGIIHNKVGLLLQIKDSNGNYGWGEVSPIEKKELEKSIESLDFIGKQTTKDSIENYLFE
LPGALAFGLGSCLADLESLTQRKLNLEGFDVAKSAYLLPTDIDPLESIRKYVDESNEKKSSCTIKWKVSHLENNFKEEKT
LQKILDILPNNFKLRIDPNGGWSRQKAQEWSNELKNEPRLEWIEQPLPSKDIEGLFSLATQIPIALDESLVEFPYLRKTW
KSWQIRRPALDGDPRLLLKEIEQEDSQTVISTAFETGIGRRWVNHLAARQVKGGNPCSPGLAPGWCPKGPLFNNNPKLVW
EAV

Sequences:

>Translated_323_residues
MKLIINIKPFSFQLTRKLITSQGIIHNKVGLLLQIKDSNGNYGWGEVSPIEKKELEKSIESLDFIGKQTTKDSIENYLFE
LPGALAFGLGSCLADLESLTQRKLNLEGFDVAKSAYLLPTDIDPLESIRKYVDESNEKKSSCTIKWKVSHLENNFKEEKT
LQKILDILPNNFKLRIDPNGGWSRQKAQEWSNELKNEPRLEWIEQPLPSKDIEGLFSLATQIPIALDESLVEFPYLRKTW
KSWQIRRPALDGDPRLLLKEIEQEDSQTVISTAFETGIGRRWVNHLAARQVKGGNPCSPGLAPGWCPKGPLFNNNPKLVW
EAV
>Mature_323_residues
MKLIINIKPFSFQLTRKLITSQGIIHNKVGLLLQIKDSNGNYGWGEVSPIEKKELEKSIESLDFIGKQTTKDSIENYLFE
LPGALAFGLGSCLADLESLTQRKLNLEGFDVAKSAYLLPTDIDPLESIRKYVDESNEKKSSCTIKWKVSHLENNFKEEKT
LQKILDILPNNFKLRIDPNGGWSRQKAQEWSNELKNEPRLEWIEQPLPSKDIEGLFSLATQIPIALDESLVEFPYLRKTW
KSWQIRRPALDGDPRLLLKEIEQEDSQTVISTAFETGIGRRWVNHLAARQVKGGNPCSPGLAPGWCPKGPLFNNNPKLVW
EAV

Specific function: Converts SHCHC to OSB [H]

COG id: COG4948

COG function: function code MR; L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013342
- InterPro:   IPR001354
- InterPro:   IPR010196 [H]

Pfam domain/function: PF01188 MR_MLE [H]

EC number: =4.2.1.113 [H]

Molecular weight: Translated: 36695; Mature: 36695

Theoretical pI: Translated: 7.38; Mature: 7.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLIINIKPFSFQLTRKLITSQGIIHNKVGLLLQIKDSNGNYGWGEVSPIEKKELEKSIE
CEEEEECCCCHHHHHHHHHHHCCCEECCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHH
SLDFIGKQTTKDSIENYLFELPGALAFGLGSCLADLESLTQRKLNLEGFDVAKSAYLLPT
HHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCC
DIDPLESIRKYVDESNEKKSSCTIKWKVSHLENNFKEEKTLQKILDILPNNFKLRIDPNG
CCCHHHHHHHHHCCCCCCCCCCEEEEEHHHHHCCHHHHHHHHHHHHHCCCCCEEEECCCC
GWSRQKAQEWSNELKNEPRLEWIEQPLPSKDIEGLFSLATQIPIALDESLVEFPYLRKTW
CCCHHHHHHHHHHHCCCCCHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
KSWQIRRPALDGDPRLLLKEIEQEDSQTVISTAFETGIGRRWVNHLAARQVKGGNPCSPG
HCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
LAPGWCPKGPLFNNNPKLVWEAV
CCCCCCCCCCCCCCCCCEEEEEC
>Mature Secondary Structure
MKLIINIKPFSFQLTRKLITSQGIIHNKVGLLLQIKDSNGNYGWGEVSPIEKKELEKSIE
CEEEEECCCCHHHHHHHHHHHCCCEECCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHH
SLDFIGKQTTKDSIENYLFELPGALAFGLGSCLADLESLTQRKLNLEGFDVAKSAYLLPT
HHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCC
DIDPLESIRKYVDESNEKKSSCTIKWKVSHLENNFKEEKTLQKILDILPNNFKLRIDPNG
CCCHHHHHHHHHCCCCCCCCCCEEEEEHHHHHCCHHHHHHHHHHHHHCCCCCEEEECCCC
GWSRQKAQEWSNELKNEPRLEWIEQPLPSKDIEGLFSLATQIPIALDESLVEFPYLRKTW
CCCHHHHHHHHHHHCCCCCHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
KSWQIRRPALDGDPRLLLKEIEQEDSQTVISTAFETGIGRRWVNHLAARQVKGGNPCSPG
HCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
LAPGWCPKGPLFNNNPKLVWEAV
CCCCCCCCCCCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]