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The map label for this gene is sms [H]

Identifier: 124024918

GI number: 124024918

Start: 190824

End: 192203

Strand: Reverse

Name: sms [H]

Synonym: NATL1_02051

Alternate gene names: 124024918

Gene position: 192203-190824 (Counterclockwise)

Preceding gene: 124024924

Following gene: 124024916

Centisome position: 10.31

GC content: 37.83

Gene sequence:

>1380_bases
GTGTCTCGTTCTGTCTCTATTTATGTCTGTCAAAGTTGCGGTGCTCAAACTAGGCAATTCTTTGGTCGCTGCAATAATTG
TGGAGAATGGAACTCAATAATAGAAGAAAAAATTAATCAAAAATCAGATAAATCTATTTACACAAAGATTAATTCTCCTA
AGGAAAAATCTCCCTATCGTTCAGAACTAATAAGCCAAACAAAAAACCAACTTATTGAACGCATTTCGAGTGGATATAAG
GAATTAGACAGGGTACTTGGAGGTGGCTTAGTGCCTGGATCACTTGTATTAATTGGGGGAGACCCAGGTATTGGGAAAAG
CACTCTTATTTTGCAAAGTGCGACTGAAATGGCTCATCACAGATCAGTCCTTTATGTGGCTGCTGAAGAATCTGCTCAAC
AAGTAAAACTTAGATGGAATCGAATTGAGGATGCTGAGTCCAATCTTCATTTACTCGCAGAAACAGATCTAGAGATGGTT
ATAAAAGAGCTTGATCATTTGAAACCTGAGGTTGCAGTGATTGATAGTATTCAAGCTTTACATGATCAAAATTTATCAAG
TTCACCCGGCTCAGTAGCTCAAGTTAGAGAATGTTCAGCAGCTTTACAGCAAATTGCTAAACGACAAAACATATCCCTTT
TGATCATCGGGCACGTTACAAAGGATGGAATGTTAGCCGGACCCAAAGTTCTTGAGCATCTTGTGGATGCAGTACTTACT
TTTGAGGGCGATCGATTCGCTTCTCACAGACTACTAAGAGGTGTGAAAAATCGCTTTGGTGCCACTTCTGAGCTTGGAGT
CTTTGAAATGCAGGCAGATGGATTATCGGAGGTTCCTAATCCAAGTGAATTATTTTTAAGCAAAACCTCTGCACCTGGGA
TTTCAACAATTGTTACTTGTGAGGGAACAAGACCATTAGCCATCGATATACAAGCACTTTTAAATCCCACGAGTTATGCA
AGTCCAAGAAGAACTACAACTGGCATTGAGATAAACAGGCTTCATCAAATCTTGGCAGTTCTAGAAAAGAATATGAATCT
TTCGCTCTCAAGATATGACTGTTATCTGGCTGTAGCTGGGGGATTAGAAGTAGAAGAACCTGGGGCTGATTTAGGAATAG
CTGCTGCAATAGTTTCGAGCTTTAAAGATATTGAGCTTGAAGAAGGTGTAGTTTTTATAGGAGAGATAGGTTTGGCTGGT
CAATTAAGATTAGTCAGACAAATGCAACAACGAATTAACGAAGTGATAAGACTTGGATATAAGACATTAATTATCCCAGA
TGGAATAGACACAAGTGAGTTTGAAACGAATCAAAAATTAAAAATATTAAAAGCTTCTAATATTAATCAAGCTTTAATAT
ATGCTTTAGATAATAATTAA

Upstream 100 bases:

>100_bases
TTAGCTTTGGCGGCTTCGACAAGATCTTAAGCGAAGGTTCACTAACATTTAAAGATCACTATCTTTATTCAACTACAGCC
AACTTCCTTTTTACAACTAA

Downstream 100 bases:

>100_bases
TCCGCGTTTTAGTTACTTATAAATAAACATCAACATTACCTCTGCCTGTAGTCTTCAGCCAATTTTCTATATCTAAATAT
CCTCCTGGGTATAAACGAAC

Product: DNA repair protein RadA

Products: NA

Alternate protein names: DNA repair protein sms homolog [H]

Number of amino acids: Translated: 459; Mature: 458

Protein sequence:

>459_residues
MSRSVSIYVCQSCGAQTRQFFGRCNNCGEWNSIIEEKINQKSDKSIYTKINSPKEKSPYRSELISQTKNQLIERISSGYK
ELDRVLGGGLVPGSLVLIGGDPGIGKSTLILQSATEMAHHRSVLYVAAEESAQQVKLRWNRIEDAESNLHLLAETDLEMV
IKELDHLKPEVAVIDSIQALHDQNLSSSPGSVAQVRECSAALQQIAKRQNISLLIIGHVTKDGMLAGPKVLEHLVDAVLT
FEGDRFASHRLLRGVKNRFGATSELGVFEMQADGLSEVPNPSELFLSKTSAPGISTIVTCEGTRPLAIDIQALLNPTSYA
SPRRTTTGIEINRLHQILAVLEKNMNLSLSRYDCYLAVAGGLEVEEPGADLGIAAAIVSSFKDIELEEGVVFIGEIGLAG
QLRLVRQMQQRINEVIRLGYKTLIIPDGIDTSEFETNQKLKILKASNINQALIYALDNN

Sequences:

>Translated_459_residues
MSRSVSIYVCQSCGAQTRQFFGRCNNCGEWNSIIEEKINQKSDKSIYTKINSPKEKSPYRSELISQTKNQLIERISSGYK
ELDRVLGGGLVPGSLVLIGGDPGIGKSTLILQSATEMAHHRSVLYVAAEESAQQVKLRWNRIEDAESNLHLLAETDLEMV
IKELDHLKPEVAVIDSIQALHDQNLSSSPGSVAQVRECSAALQQIAKRQNISLLIIGHVTKDGMLAGPKVLEHLVDAVLT
FEGDRFASHRLLRGVKNRFGATSELGVFEMQADGLSEVPNPSELFLSKTSAPGISTIVTCEGTRPLAIDIQALLNPTSYA
SPRRTTTGIEINRLHQILAVLEKNMNLSLSRYDCYLAVAGGLEVEEPGADLGIAAAIVSSFKDIELEEGVVFIGEIGLAG
QLRLVRQMQQRINEVIRLGYKTLIIPDGIDTSEFETNQKLKILKASNINQALIYALDNN
>Mature_458_residues
SRSVSIYVCQSCGAQTRQFFGRCNNCGEWNSIIEEKINQKSDKSIYTKINSPKEKSPYRSELISQTKNQLIERISSGYKE
LDRVLGGGLVPGSLVLIGGDPGIGKSTLILQSATEMAHHRSVLYVAAEESAQQVKLRWNRIEDAESNLHLLAETDLEMVI
KELDHLKPEVAVIDSIQALHDQNLSSSPGSVAQVRECSAALQQIAKRQNISLLIIGHVTKDGMLAGPKVLEHLVDAVLTF
EGDRFASHRLLRGVKNRFGATSELGVFEMQADGLSEVPNPSELFLSKTSAPGISTIVTCEGTRPLAIDIQALLNPTSYAS
PRRTTTGIEINRLHQILAVLEKNMNLSLSRYDCYLAVAGGLEVEEPGADLGIAAAIVSSFKDIELEEGVVFIGEIGLAGQ
LRLVRQMQQRINEVIRLGYKTLIIPDGIDTSEFETNQKLKILKASNINQALIYALDNN

Specific function: May play a role in the repair of endogenous alkylation damage [H]

COG id: COG1066

COG function: function code O; Predicted ATP-dependent serine protease

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recA family. RadA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790850, Length=422, Percent_Identity=43.8388625592417, Blast_Score=361, Evalue=1e-101,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR014774
- InterPro:   IPR004504
- InterPro:   IPR008269
- InterPro:   IPR020568 [H]

Pfam domain/function: PF06745 KaiC; PF05362 Lon_C [H]

EC number: NA

Molecular weight: Translated: 50290; Mature: 50159

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: PS50162 RECA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRSVSIYVCQSCGAQTRQFFGRCNNCGEWNSIIEEKINQKSDKSIYTKINSPKEKSPYR
CCCCEEEEEECCCCHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCCHH
SELISQTKNQLIERISSGYKELDRVLGGGLVPGSLVLIGGDPGIGKSTLILQSATEMAHH
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCEEEEHHHHHHHHC
RSVLYVAAEESAQQVKLRWNRIEDAESNLHLLAETDLEMVIKELDHLKPEVAVIDSIQAL
CEEEEEEECCCHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHH
HDQNLSSSPGSVAQVRECSAALQQIAKRQNISLLIIGHVTKDGMLAGPKVLEHLVDAVLT
HCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHH
FEGDRFASHRLLRGVKNRFGATSELGVFEMQADGLSEVPNPSELFLSKTSAPGISTIVTC
CCCCHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCHHHHEECCCCCCCEEEEEE
EGTRPLAIDIQALLNPTSYASPRRTTTGIEINRLHQILAVLEKNMNLSLSRYDCYLAVAG
CCCCCEEEEHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEEEEEEEC
GLEVEEPGADLGIAAAIVSSFKDIELEEGVVFIGEIGLAGQLRLVRQMQQRINEVIRLGY
CCEECCCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCC
KTLIIPDGIDTSEFETNQKLKILKASNINQALIYALDNN
EEEEEECCCCCCCCCCCCCEEEEEECCCCEEEEEEECCC
>Mature Secondary Structure 
SRSVSIYVCQSCGAQTRQFFGRCNNCGEWNSIIEEKINQKSDKSIYTKINSPKEKSPYR
CCCEEEEEECCCCHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCCHH
SELISQTKNQLIERISSGYKELDRVLGGGLVPGSLVLIGGDPGIGKSTLILQSATEMAHH
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCEEEEHHHHHHHHC
RSVLYVAAEESAQQVKLRWNRIEDAESNLHLLAETDLEMVIKELDHLKPEVAVIDSIQAL
CEEEEEEECCCHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHH
HDQNLSSSPGSVAQVRECSAALQQIAKRQNISLLIIGHVTKDGMLAGPKVLEHLVDAVLT
HCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHH
FEGDRFASHRLLRGVKNRFGATSELGVFEMQADGLSEVPNPSELFLSKTSAPGISTIVTC
CCCCHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCHHHHEECCCCCCCEEEEEE
EGTRPLAIDIQALLNPTSYASPRRTTTGIEINRLHQILAVLEKNMNLSLSRYDCYLAVAG
CCCCCEEEEHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEEEEEEEC
GLEVEEPGADLGIAAAIVSSFKDIELEEGVVFIGEIGLAGQLRLVRQMQQRINEVIRLGY
CCEECCCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCC
KTLIIPDGIDTSEFETNQKLKILKASNINQALIYALDNN
EEEEEECCCCCCCCCCCCCEEEEEECCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]