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The map label for this gene is zntA [H]

Identifier: 124024916

GI number: 124024916

Start: 187793

End: 190123

Strand: Reverse

Name: zntA [H]

Synonym: NATL1_02031

Alternate gene names: 124024916

Gene position: 190123-187793 (Counterclockwise)

Preceding gene: 124024918

Following gene: 124024915

Centisome position: 10.2

GC content: 38.01

Gene sequence:

>2331_bases
TTGAGCAACAAAAAGATTGCCCAAAGCAAAAAGTCAATTCTGCTTGATATAGATGGAATGAGGTGCGGAAGTTGTGTACA
GGCAGTTGAAAAAATACTTAAAAACCACCCAAACATAAATAATGCAAGCGTTAATTTAGTTACAAAAACGGCTTTAGTAG
AAATTAAAGAGCCTAATTACCCCTTTGCCGATGTGATACAAACTCTTACATCAAAGGGCTTTCCAACAAGGGAAAGACCT
GATCAAACAATAACAAAAAATACCGAGTTAGAGAGAAACGAAAACCAGAATTTATGGAATAAATGGCGACAACTAATAAT
CGCTACTTCATTATTAATCCTCTCAGGGTTGGGACATTTAATAGAGGGTCAACAAATATCTTTTCCACTTATTGGTTCAT
TACCTTTTCATGCTGCACTCGCAACATTTGCTTTACTTGGACCAGGTAAATCGATCCTAAACGCAGGTATAAAGTCGGCA
ATCATGCTTACACCGACTATGGATACCTTAGTCAGTCTTGGTGTAATGAGTGCTTACATAGCAAGCATAATTGCTTTAAT
TTGGCCGACAGTTGGCTGGCCATGTTTTTTCAATGAACCGGTCATGCTGCTTGGATTTGTTTTATTAGGACGTTTTTTAG
AGGAAAGAGCACGAATCAACACTGGCACAGCATTAAAAGAATTAGCAAAATTACAACCCGAAACAGCCAATCTAATTTTA
GACAATAACGAAATTCGTGAAATTAGAATAGGTGCTCTAAGACCAGGAGAAAAAATCCAATTATTAGCGGGGGATAGAAT
CCCAGTAGATGGCTTAGTTATAAAAGGAAATTCGGCAATAGATATCTCTAGTTTAACTGGCGAGTCTTTACCGCTAGAAG
CAAAACCTGGAGTCGAGCTACCCTCTGGCAGCCTAAATTTAGAGTCAACAATCACTTTAGAAGTTCAAAAAATTGGATCT
GAAACGGCAATAGCTAAAATAATAAGTTTAGTTGAAGAAGCTCAAGCCAGAAAAGCACCAATTCAGGGATTAGCAGACAA
GGTGGCAGGTATGTTCTGCTATGGGGTAACAACTCTTTCTTTAATAACTTTTCTTTTTTGGTGGAGAATAGGTACGAGGA
TATGGCCAGAAGTTTTAGAAGTATCTAATACAGGTTTCATGCATAGCCATAACTTGCATGATCATTTAATGAATACCCCT
CAAACACCTATTGGTCTCTCATTTCAATTATCAATAGCTGTTTTAGTTGTGGCCTGTCCATGTGCACTAGGACTTGCCAC
GCCAACGGTAATAACTGTTGCTTCTGGGGAAGCGGCTAAACGAGGATGGCTTTTCAAGGGTGGAGATGTCATAGAAATGG
CCTCAAAAATTAGTCAAATTATTTTTGATAAAACAGGTACACTCACGATTGGAAGGCCTTTAGTTGTTGGCTGCTGGAAA
AACAATGAGTCAGAAAGAAATTTCATGCTCAAATTGGCGGCAAGCATTGAACTAGAAAGTCGGCATCCGCTGGCCCAAGC
AATTATTCAAGAAGCACATAAAAAAGAAATCAAACTAGAAAAAGTGTCAAGCTCAACCACGTATCCAGGTAAAGGCTTAG
CCGGCAAAATTAATAACCTAGAAGGACTTATAAGAGTCGGAACTCCCGAATGGATCAAAAGTGAAGGAATTGAATGGAAT
GAAATGATTGAAAACAATTTCAAGCTTTCAAAAAGAAAAGCTCAATCAATAGTCGCAGTTGCTCTGGATAACAAATTATT
AGGTTTTTTCTTGATTGATGACCAAATAAGAAAAGATGCTTTCCTTTCAATTAATAAATTACGCTCAAGAGGTTTTTCAT
TAAGTTTATTTAGTGGCGATAGAGATTCAGCAGTTTTATCTATAGGGGAAAAATTGGGATTTAGTGCAAAACAAGTTACA
TGGCAAATGTTGCCCTCAGACAAGCTGAATAAATTGAACTTATTAAAAAATAATGGTTTAGTCGCGATGATAGGTGATGG
AATTAATGATGCCCCAGCTCTTGCCGCTGCAGACTTAGGAGTAGCGATAGGAACCGGAACTCAAATCGCGCAAGATTCTG
CTGATCTTGTTCTGCTTGGAGAAAATTTGGAAGCCCTTCCAAATGCTTTCAATCTATCAAAGCAAGCAATGCTCAAAATA
AAACAAAACCTTGCTTGGGCATTTGGATATAACTTAATTGCTTTACCAATCGCTGCAGGATTACTTTTACCATCTTCTGG
CTTATTACTATCTCCTCCCTTGGCGGCTTTACTTATGGCTTTGAGCTCTATAAGTGTTGTACTTAATGCCTTGTCTTTGA
AGTCAAAATGA

Upstream 100 bases:

>100_bases
AATAATGAAACTAATTTTTATGTATTAATAAATCATTAAATAAATGCAACATGCTTTTTATTTATTAAATTTAGAATAAG
TATCCAAAATTTATATTCCC

Downstream 100 bases:

>100_bases
AAGGAAAGTTTATTGTTTTTGAGGGTATTGATGGCTCGGGTAAAACCACTCAAATCAATCAATTATCCAAATGGCTTATT
AGTACCGACCTCATACCTGA

Product: putative P-type ATPase transporter for copper

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 776; Mature: 775

Protein sequence:

>776_residues
MSNKKIAQSKKSILLDIDGMRCGSCVQAVEKILKNHPNINNASVNLVTKTALVEIKEPNYPFADVIQTLTSKGFPTRERP
DQTITKNTELERNENQNLWNKWRQLIIATSLLILSGLGHLIEGQQISFPLIGSLPFHAALATFALLGPGKSILNAGIKSA
IMLTPTMDTLVSLGVMSAYIASIIALIWPTVGWPCFFNEPVMLLGFVLLGRFLEERARINTGTALKELAKLQPETANLIL
DNNEIREIRIGALRPGEKIQLLAGDRIPVDGLVIKGNSAIDISSLTGESLPLEAKPGVELPSGSLNLESTITLEVQKIGS
ETAIAKIISLVEEAQARKAPIQGLADKVAGMFCYGVTTLSLITFLFWWRIGTRIWPEVLEVSNTGFMHSHNLHDHLMNTP
QTPIGLSFQLSIAVLVVACPCALGLATPTVITVASGEAAKRGWLFKGGDVIEMASKISQIIFDKTGTLTIGRPLVVGCWK
NNESERNFMLKLAASIELESRHPLAQAIIQEAHKKEIKLEKVSSSTTYPGKGLAGKINNLEGLIRVGTPEWIKSEGIEWN
EMIENNFKLSKRKAQSIVAVALDNKLLGFFLIDDQIRKDAFLSINKLRSRGFSLSLFSGDRDSAVLSIGEKLGFSAKQVT
WQMLPSDKLNKLNLLKNNGLVAMIGDGINDAPALAAADLGVAIGTGTQIAQDSADLVLLGENLEALPNAFNLSKQAMLKI
KQNLAWAFGYNLIALPIAAGLLLPSSGLLLSPPLAALLMALSSISVVLNALSLKSK

Sequences:

>Translated_776_residues
MSNKKIAQSKKSILLDIDGMRCGSCVQAVEKILKNHPNINNASVNLVTKTALVEIKEPNYPFADVIQTLTSKGFPTRERP
DQTITKNTELERNENQNLWNKWRQLIIATSLLILSGLGHLIEGQQISFPLIGSLPFHAALATFALLGPGKSILNAGIKSA
IMLTPTMDTLVSLGVMSAYIASIIALIWPTVGWPCFFNEPVMLLGFVLLGRFLEERARINTGTALKELAKLQPETANLIL
DNNEIREIRIGALRPGEKIQLLAGDRIPVDGLVIKGNSAIDISSLTGESLPLEAKPGVELPSGSLNLESTITLEVQKIGS
ETAIAKIISLVEEAQARKAPIQGLADKVAGMFCYGVTTLSLITFLFWWRIGTRIWPEVLEVSNTGFMHSHNLHDHLMNTP
QTPIGLSFQLSIAVLVVACPCALGLATPTVITVASGEAAKRGWLFKGGDVIEMASKISQIIFDKTGTLTIGRPLVVGCWK
NNESERNFMLKLAASIELESRHPLAQAIIQEAHKKEIKLEKVSSSTTYPGKGLAGKINNLEGLIRVGTPEWIKSEGIEWN
EMIENNFKLSKRKAQSIVAVALDNKLLGFFLIDDQIRKDAFLSINKLRSRGFSLSLFSGDRDSAVLSIGEKLGFSAKQVT
WQMLPSDKLNKLNLLKNNGLVAMIGDGINDAPALAAADLGVAIGTGTQIAQDSADLVLLGENLEALPNAFNLSKQAMLKI
KQNLAWAFGYNLIALPIAAGLLLPSSGLLLSPPLAALLMALSSISVVLNALSLKSK
>Mature_775_residues
SNKKIAQSKKSILLDIDGMRCGSCVQAVEKILKNHPNINNASVNLVTKTALVEIKEPNYPFADVIQTLTSKGFPTRERPD
QTITKNTELERNENQNLWNKWRQLIIATSLLILSGLGHLIEGQQISFPLIGSLPFHAALATFALLGPGKSILNAGIKSAI
MLTPTMDTLVSLGVMSAYIASIIALIWPTVGWPCFFNEPVMLLGFVLLGRFLEERARINTGTALKELAKLQPETANLILD
NNEIREIRIGALRPGEKIQLLAGDRIPVDGLVIKGNSAIDISSLTGESLPLEAKPGVELPSGSLNLESTITLEVQKIGSE
TAIAKIISLVEEAQARKAPIQGLADKVAGMFCYGVTTLSLITFLFWWRIGTRIWPEVLEVSNTGFMHSHNLHDHLMNTPQ
TPIGLSFQLSIAVLVVACPCALGLATPTVITVASGEAAKRGWLFKGGDVIEMASKISQIIFDKTGTLTIGRPLVVGCWKN
NESERNFMLKLAASIELESRHPLAQAIIQEAHKKEIKLEKVSSSTTYPGKGLAGKINNLEGLIRVGTPEWIKSEGIEWNE
MIENNFKLSKRKAQSIVAVALDNKLLGFFLIDDQIRKDAFLSINKLRSRGFSLSLFSGDRDSAVLSIGEKLGFSAKQVTW
QMLPSDKLNKLNLLKNNGLVAMIGDGINDAPALAAADLGVAIGTGTQIAQDSADLVLLGENLEALPNAFNLSKQAMLKIK
QNLAWAFGYNLIALPIAAGLLLPSSGLLLSPPLAALLMALSSISVVLNALSLKSK

Specific function: Involved in copper transport [H]

COG id: COG2217

COG function: function code P; Cation transport ATPase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HMA domain [H]

Homologues:

Organism=Homo sapiens, GI115529486, Length=838, Percent_Identity=31.3842482100239, Blast_Score=386, Evalue=1e-107,
Organism=Homo sapiens, GI55743071, Length=823, Percent_Identity=31.9562575941677, Blast_Score=382, Evalue=1e-106,
Organism=Homo sapiens, GI55743073, Length=577, Percent_Identity=32.2357019064125, Blast_Score=286, Evalue=5e-77,
Organism=Homo sapiens, GI48762687, Length=605, Percent_Identity=21.9834710743802, Blast_Score=89, Evalue=2e-17,
Organism=Homo sapiens, GI48762691, Length=605, Percent_Identity=21.9834710743802, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI48762685, Length=605, Percent_Identity=21.9834710743802, Blast_Score=88, Evalue=3e-17,
Organism=Homo sapiens, GI48762689, Length=605, Percent_Identity=21.9834710743802, Blast_Score=88, Evalue=4e-17,
Organism=Homo sapiens, GI118498343, Length=179, Percent_Identity=27.3743016759777, Blast_Score=68, Evalue=4e-11,
Organism=Escherichia coli, GI1786691, Length=779, Percent_Identity=31.8356867779204, Blast_Score=347, Evalue=2e-96,
Organism=Escherichia coli, GI1789879, Length=759, Percent_Identity=28.7220026350461, Blast_Score=262, Evalue=5e-71,
Organism=Escherichia coli, GI1786914, Length=499, Percent_Identity=24.0480961923848, Blast_Score=111, Evalue=2e-25,
Organism=Escherichia coli, GI2367363, Length=188, Percent_Identity=26.5957446808511, Blast_Score=63, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17556548, Length=820, Percent_Identity=30.3658536585366, Blast_Score=298, Evalue=6e-81,
Organism=Saccharomyces cerevisiae, GI6320475, Length=651, Percent_Identity=34.1013824884793, Blast_Score=324, Evalue=4e-89,
Organism=Saccharomyces cerevisiae, GI6319772, Length=658, Percent_Identity=30.3951367781155, Blast_Score=290, Evalue=7e-79,
Organism=Saccharomyces cerevisiae, GI6325221, Length=580, Percent_Identity=23.7931034482759, Blast_Score=102, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6321430, Length=580, Percent_Identity=22.9310344827586, Blast_Score=95, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6321271, Length=204, Percent_Identity=25.9803921568627, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI221329854, Length=573, Percent_Identity=31.413612565445, Blast_Score=213, Evalue=4e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008250
- InterPro:   IPR006403
- InterPro:   IPR006416
- InterPro:   IPR001757
- InterPro:   IPR018303
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR017969
- InterPro:   IPR006121
- InterPro:   IPR000150 [H]

Pfam domain/function: PF00122 E1-E2_ATPase; PF00403 HMA; PF00702 Hydrolase [H]

EC number: =3.6.3.4 [H]

Molecular weight: Translated: 83918; Mature: 83787

Theoretical pI: Translated: 8.97; Mature: 8.97

Prosite motif: PS00154 ATPASE_E1_E2 ; PS01047 HMA_1 ; PS50846 HMA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNKKIAQSKKSILLDIDGMRCGSCVQAVEKILKNHPNINNASVNLVTKTALVEIKEPNY
CCCCHHHHCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEEEEECCCC
PFADVIQTLTSKGFPTRERPDQTITKNTELERNENQNLWNKWRQLIIATSLLILSGLGHL
CHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IEGQQISFPLIGSLPFHAALATFALLGPGKSILNAGIKSAIMLTPTMDTLVSLGVMSAYI
HCCCEECCCEECCCHHHHHHHHHHHHCCCHHHHHHCCCCEEEECCCHHHHHHHHHHHHHH
ASIIALIWPTVGWPCFFNEPVMLLGFVLLGRFLEERARINTGTALKELAKLQPETANLIL
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCEEEE
DNNEIREIRIGALRPGEKIQLLAGDRIPVDGLVIKGNSAIDISSLTGESLPLEAKPGVEL
CCCCEEEEEEECCCCCCEEEEEECCCCCCCCEEEECCCEEEEECCCCCCCCCCCCCCCCC
PSGSLNLESTITLEVQKIGSETAIAKIISLVEEAQARKAPIQGLADKVAGMFCYGVTTLS
CCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
LITFLFWWRIGTRIWPEVLEVSNTGFMHSHNLHDHLMNTPQTPIGLSFQLSIAVLVVACP
HHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCHHHHCCCCCCCCCEEHHHHHHHHHHHHH
CALGLATPTVITVASGEAAKRGWLFKGGDVIEMASKISQIIFDKTGTLTIGRPLVVGCWK
HHHCCCCCCEEEEECCCHHHCCCEECCCHHHHHHHHHHHHHHCCCCCEEECCCEEEEEEC
NNESERNFMLKLAASIELESRHPLAQAIIQEAHKKEIKLEKVSSSTTYPGKGLAGKINNL
CCCCCHHEEEEEEEEEEECCCCHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCCCCCC
EGLIRVGTPEWIKSEGIEWNEMIENNFKLSKRKAQSIVAVALDNKLLGFFLIDDQIRKDA
CCEEEECCCHHHHHCCCCHHHHHHCCCHHHHHHHHHEEEEEECCCEEEEEEECHHHHHHH
FLSINKLRSRGFSLSLFSGDRDSAVLSIGEKLGFSAKQVTWQMLPSDKLNKLNLLKNNGL
HHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHCCCHHHHEEEECCCCCCCCEEEEECCCE
VAMIGDGINDAPALAAADLGVAIGTGTQIAQDSADLVLLGENLEALPNAFNLSKQAMLKI
EEEECCCCCCCCHHHHHHCCEEECCCCCCCCCCCCEEEECCCHHHCCCHHCCCHHHHHHH
KQNLAWAFGYNLIALPIAAGLLLPSSGLLLSPPLAALLMALSSISVVLNALSLKSK
HHHHHHHHCCHHHHHHHHHHHHCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SNKKIAQSKKSILLDIDGMRCGSCVQAVEKILKNHPNINNASVNLVTKTALVEIKEPNY
CCCHHHHCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEEEEECCCC
PFADVIQTLTSKGFPTRERPDQTITKNTELERNENQNLWNKWRQLIIATSLLILSGLGHL
CHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IEGQQISFPLIGSLPFHAALATFALLGPGKSILNAGIKSAIMLTPTMDTLVSLGVMSAYI
HCCCEECCCEECCCHHHHHHHHHHHHCCCHHHHHHCCCCEEEECCCHHHHHHHHHHHHHH
ASIIALIWPTVGWPCFFNEPVMLLGFVLLGRFLEERARINTGTALKELAKLQPETANLIL
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCEEEE
DNNEIREIRIGALRPGEKIQLLAGDRIPVDGLVIKGNSAIDISSLTGESLPLEAKPGVEL
CCCCEEEEEEECCCCCCEEEEEECCCCCCCCEEEECCCEEEEECCCCCCCCCCCCCCCCC
PSGSLNLESTITLEVQKIGSETAIAKIISLVEEAQARKAPIQGLADKVAGMFCYGVTTLS
CCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
LITFLFWWRIGTRIWPEVLEVSNTGFMHSHNLHDHLMNTPQTPIGLSFQLSIAVLVVACP
HHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCHHHHCCCCCCCCCEEHHHHHHHHHHHHH
CALGLATPTVITVASGEAAKRGWLFKGGDVIEMASKISQIIFDKTGTLTIGRPLVVGCWK
HHHCCCCCCEEEEECCCHHHCCCEECCCHHHHHHHHHHHHHHCCCCCEEECCCEEEEEEC
NNESERNFMLKLAASIELESRHPLAQAIIQEAHKKEIKLEKVSSSTTYPGKGLAGKINNL
CCCCCHHEEEEEEEEEEECCCCHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCCCCCC
EGLIRVGTPEWIKSEGIEWNEMIENNFKLSKRKAQSIVAVALDNKLLGFFLIDDQIRKDA
CCEEEECCCHHHHHCCCCHHHHHHCCCHHHHHHHHHEEEEEECCCEEEEEEECHHHHHHH
FLSINKLRSRGFSLSLFSGDRDSAVLSIGEKLGFSAKQVTWQMLPSDKLNKLNLLKNNGL
HHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHCCCHHHHEEEECCCCCCCCEEEEECCCE
VAMIGDGINDAPALAAADLGVAIGTGTQIAQDSADLVLLGENLEALPNAFNLSKQAMLKI
EEEECCCCCCCCHHHHHHCCEEECCCCCCCCCCCCEEEECCCHHHCCCHHCCCHHHHHHH
KQNLAWAFGYNLIALPIAAGLLLPSSGLLLSPPLAALLMALSSISVVLNALSLKSK
HHHHHHHHCCHHHHHHHHHHHHCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7937823 [H]