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The map label for this gene is trpS [H]

Identifier: 124023565

GI number: 124023565

Start: 1626246

End: 1627259

Strand: Reverse

Name: trpS [H]

Synonym: P9303_18651

Alternate gene names: 124023565

Gene position: 1627259-1626246 (Counterclockwise)

Preceding gene: 124023566

Following gene: 124023564

Centisome position: 60.66

GC content: 54.64

Gene sequence:

>1014_bases
ATGCAGCGCCCGCGGGTCCTTTCCGGCGTCCAGCCGACAGGTGCCCTCCATCTGGGTAACTGGTTGGGGGCCATCCGCAA
CTGGGTAGATCTTCAGAGCAGCCATGACACCTATGTCTGTGTCGTGGATTTACACGCCATTACCGTTCCGCACGATCCAG
AACGTTTGGCCGAGGAGACCCTCTCCACAGCCGCTCTCTACCTGGCCTGTGGGATGGATCCAGATCTCTGCAGCATCTTT
GTGCAGAGCCAGGTTTCCGCCCACAGTGAGCTCTGTTGGTTGCTGAACTGTGTTACGCCTCTGAACTGGCTAGAGCGAAT
GATCCAGTTCAAAGAGAAGTCAGTCAAACAGGGGGACAACGTTTCTGTGGGACTGCTGGACTATCCGGTGTTAATGGCAG
CAGACATTCTTCTTTATGACGCTGATTTGGTGCCCGTGGGCGAAGACCAGAAACAACATTTAGAACTCGCCCGTGACATT
GCTCAGCAGCGCATCAATGCCCGCTTCGGTAGTGAAGAGAAACCTGTCCTTAAAGTCCCAGATCCCCTGATCATTAAAGA
GGGGGCAAGAGTGATGAGCCTTAGCGATGGCCGCAGCAAGATGAGTAAAAGTGACCCCAATGAAGGAAGTCGTATCACAC
TGCTTGATCCGCCTGAACTGATCACAAAAAAAATCAAGCGGGCCAAGACAGATCCCCAAATGGGCTTGCAATTTGGCAAC
CCAGACCGCCCGGAGGCCGACAATCTGCTTGGGATTTACGCCATCCTTAGTGGCCGGGGAAGAGACGCAGCTGCCCAAGA
ATGCGCAGAAATGGGATGGGGAACCTTCAAGCCTCTGCTGGCCGACGCCACGGTGTCAGCTCTTGAGCCGATACAGCATC
GCTATCAACAACTCATGGGCGACCGCATTGAACTCATCAGAGTTCTTGACCAAGGCAGGACCACAGCGCAAGAGACCGCC
CAAGCAACCCTTCAACGAGTTCACCAGGCCCTTGGCTTCCTGATAGCCAGCTAA

Upstream 100 bases:

>100_bases
ATTGCACTCAGCAGAGCAAGAGCAGGACCAGGCTGCTGAAACTGAACAAGTGCAGGCTATAGAGCATGAACCTGAGAATG
CACCTAGTGAGGGCTGATTA

Downstream 100 bases:

>100_bases
TTAATACAGGCTGAAAGAAAAGTTTTGCTAATCATTGGAGCCCAGTGATGACCGAGGCATCCTTGCGGCACTGAAGTCAG
CGAGTTCTAGTCATCAGCAA

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MQRPRVLSGVQPTGALHLGNWLGAIRNWVDLQSSHDTYVCVVDLHAITVPHDPERLAEETLSTAALYLACGMDPDLCSIF
VQSQVSAHSELCWLLNCVTPLNWLERMIQFKEKSVKQGDNVSVGLLDYPVLMAADILLYDADLVPVGEDQKQHLELARDI
AQQRINARFGSEEKPVLKVPDPLIIKEGARVMSLSDGRSKMSKSDPNEGSRITLLDPPELITKKIKRAKTDPQMGLQFGN
PDRPEADNLLGIYAILSGRGRDAAAQECAEMGWGTFKPLLADATVSALEPIQHRYQQLMGDRIELIRVLDQGRTTAQETA
QATLQRVHQALGFLIAS

Sequences:

>Translated_337_residues
MQRPRVLSGVQPTGALHLGNWLGAIRNWVDLQSSHDTYVCVVDLHAITVPHDPERLAEETLSTAALYLACGMDPDLCSIF
VQSQVSAHSELCWLLNCVTPLNWLERMIQFKEKSVKQGDNVSVGLLDYPVLMAADILLYDADLVPVGEDQKQHLELARDI
AQQRINARFGSEEKPVLKVPDPLIIKEGARVMSLSDGRSKMSKSDPNEGSRITLLDPPELITKKIKRAKTDPQMGLQFGN
PDRPEADNLLGIYAILSGRGRDAAAQECAEMGWGTFKPLLADATVSALEPIQHRYQQLMGDRIELIRVLDQGRTTAQETA
QATLQRVHQALGFLIAS
>Mature_337_residues
MQRPRVLSGVQPTGALHLGNWLGAIRNWVDLQSSHDTYVCVVDLHAITVPHDPERLAEETLSTAALYLACGMDPDLCSIF
VQSQVSAHSELCWLLNCVTPLNWLERMIQFKEKSVKQGDNVSVGLLDYPVLMAADILLYDADLVPVGEDQKQHLELARDI
AQQRINARFGSEEKPVLKVPDPLIIKEGARVMSLSDGRSKMSKSDPNEGSRITLLDPPELITKKIKRAKTDPQMGLQFGN
PDRPEADNLLGIYAILSGRGRDAAAQECAEMGWGTFKPLLADATVSALEPIQHRYQQLMGDRIELIRVLDQGRTTAQETA
QATLQRVHQALGFLIAS

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=333, Percent_Identity=41.1411411411411, Blast_Score=256, Evalue=2e-68,
Organism=Homo sapiens, GI41352700, Length=175, Percent_Identity=52.5714285714286, Blast_Score=181, Evalue=7e-46,
Organism=Escherichia coli, GI1789786, Length=336, Percent_Identity=46.7261904761905, Blast_Score=301, Evalue=3e-83,
Organism=Caenorhabditis elegans, GI71982800, Length=337, Percent_Identity=34.7181008902077, Blast_Score=182, Evalue=3e-46,
Organism=Caenorhabditis elegans, GI71982793, Length=337, Percent_Identity=34.7181008902077, Blast_Score=180, Evalue=8e-46,
Organism=Saccharomyces cerevisiae, GI6320474, Length=349, Percent_Identity=36.9627507163324, Blast_Score=205, Evalue=7e-54,
Organism=Drosophila melanogaster, GI24666151, Length=333, Percent_Identity=44.1441441441441, Blast_Score=258, Evalue=3e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 37262; Mature: 37262

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRPRVLSGVQPTGALHLGNWLGAIRNWVDLQSSHDTYVCVVDLHAITVPHDPERLAEET
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEECCCCHHHHHHHH
LSTAALYLACGMDPDLCSIFVQSQVSAHSELCWLLNCVTPLNWLERMIQFKEKSVKQGDN
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCC
VSVGLLDYPVLMAADILLYDADLVPVGEDQKQHLELARDIAQQRINARFGSEEKPVLKVP
CEEEHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEECC
DPLIIKEGARVMSLSDGRSKMSKSDPNEGSRITLLDPPELITKKIKRAKTDPQMGLQFGN
CCEEECCCCEEEEECCCHHHHCCCCCCCCCEEEEECCHHHHHHHHHHCCCCHHHCCCCCC
PDRPEADNLLGIYAILSGRGRDAAAQECAEMGWGTFKPLLADATVSALEPIQHRYQQLMG
CCCCCCHHHEEHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
DRIELIRVLDQGRTTAQETAQATLQRVHQALGFLIAS
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQRPRVLSGVQPTGALHLGNWLGAIRNWVDLQSSHDTYVCVVDLHAITVPHDPERLAEET
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEECCCCHHHHHHHH
LSTAALYLACGMDPDLCSIFVQSQVSAHSELCWLLNCVTPLNWLERMIQFKEKSVKQGDN
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCC
VSVGLLDYPVLMAADILLYDADLVPVGEDQKQHLELARDIAQQRINARFGSEEKPVLKVP
CEEEHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEECC
DPLIIKEGARVMSLSDGRSKMSKSDPNEGSRITLLDPPELITKKIKRAKTDPQMGLQFGN
CCEEECCCCEEEEECCCHHHHCCCCCCCCCEEEEECCHHHHHHHHHHCCCCHHHCCCCCC
PDRPEADNLLGIYAILSGRGRDAAAQECAEMGWGTFKPLLADATVSALEPIQHRYQQLMG
CCCCCCHHHEEHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
DRIELIRVLDQGRTTAQETAQATLQRVHQALGFLIAS
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12917642 [H]