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The map label for this gene is ubiA [H]

Identifier: 124022368

GI number: 124022368

Start: 619150

End: 620043

Strand: Reverse

Name: ubiA [H]

Synonym: P9303_06581

Alternate gene names: 124022368

Gene position: 620043-619150 (Counterclockwise)

Preceding gene: 124022370

Following gene: 124022367

Centisome position: 23.11

GC content: 58.05

Gene sequence:

>894_bases
GTGACCAGCAGATCCGTCTCTAATGGCTTAAGGCAATGGCTAGAGCTGCTGCGATGGCACAAACCCAGTGGTCGGCTCAT
CCTTCTCGTGCCAGCAGGTTGGAGTCTTTGGCTCACTCCTGACGCACCTCCTTTGGCAGGGCTTGTGAGTCTGATCGTTG
TTGGAGGTCTGATGGTGAGCGGCGCCGGTTGCATTGCCAATGATCTCTGGGATCGACGCATTGATCGCCAGGTGGAGCGC
ACGAGGGAACGGCCACTCGCGAAGGGCAGCATTCGCATTTCCACTGCTGTGGGCTTATTGATTGTGTTGTTGCTGCTCAG
CCTTTTGGTCGTGGTCTCCCTGCCAACGCCAAGCCGGGGCCTATGCCTTGCTCTAGCCATCCTAGCCTTGCCACCGATCC
TGCTCTATCCCTCCGCCAAGCGCTGGTTTGCCTATCCACAAGCGGTGCTTGCCCTCTGCTGGGGGTTTGCCGTACTGATC
CCCTGGGCGGCAAGCCAGGCCAATCTCAACGGAGGCTGGCCACTGCTGGGCTGCTGGTTGGCCACTCTGATGTGGACGTT
CGGCTTTGACACGGTTTACGCCATGGCGGATCGTCGTGACGACGCCAACCTGGCCTTAAAAAGCAGTGCTTTGAGCTTGG
GGAGCCATGCACTTAAAACTGTCGCGTTTAGTTATGCACTGGCCTGCACCTTTCTGGCTAGTGCAGCAATGAGCGCAGGA
GTGGGCTGGGCCTTTTGGCCCTTCTGGCTCATCGCCAGCATCGGCATGCAAAAAGAAACGTGGACCCTGCGAGGTTCCAA
TCAACCAATGACGACCTACGGGCAGCACTTTCAGCATCAAGTTCTGCTAGGCGCGATGTTGCTGCTCGGCTTGATCCTGG
GGCGCATCAGCTGA

Upstream 100 bases:

>100_bases
ACACCTGGCATGAAGTACAGGAGCCTGGAACGAGACCACTTTGCCATCAGCCAACGATGTCTGGAGGTCCCTCCCTAGGG
TTCTTCAAACCCAGAAACCC

Downstream 100 bases:

>100_bases
ATCATGGTGCAGCTCCGATCTGACCTGCTCACACCAGCGCTTCAACGTGGCGACGAGGTGATCACAGTGGCTGCGAGTTC
AGCGCTGGAGGATGAACAAT

Product: prenyltransferase

Products: NA

Alternate protein names: 4-HB polyprenyltransferase [H]

Number of amino acids: Translated: 297; Mature: 296

Protein sequence:

>297_residues
MTSRSVSNGLRQWLELLRWHKPSGRLILLVPAGWSLWLTPDAPPLAGLVSLIVVGGLMVSGAGCIANDLWDRRIDRQVER
TRERPLAKGSIRISTAVGLLIVLLLLSLLVVVSLPTPSRGLCLALAILALPPILLYPSAKRWFAYPQAVLALCWGFAVLI
PWAASQANLNGGWPLLGCWLATLMWTFGFDTVYAMADRRDDANLALKSSALSLGSHALKTVAFSYALACTFLASAAMSAG
VGWAFWPFWLIASIGMQKETWTLRGSNQPMTTYGQHFQHQVLLGAMLLLGLILGRIS

Sequences:

>Translated_297_residues
MTSRSVSNGLRQWLELLRWHKPSGRLILLVPAGWSLWLTPDAPPLAGLVSLIVVGGLMVSGAGCIANDLWDRRIDRQVER
TRERPLAKGSIRISTAVGLLIVLLLLSLLVVVSLPTPSRGLCLALAILALPPILLYPSAKRWFAYPQAVLALCWGFAVLI
PWAASQANLNGGWPLLGCWLATLMWTFGFDTVYAMADRRDDANLALKSSALSLGSHALKTVAFSYALACTFLASAAMSAG
VGWAFWPFWLIASIGMQKETWTLRGSNQPMTTYGQHFQHQVLLGAMLLLGLILGRIS
>Mature_296_residues
TSRSVSNGLRQWLELLRWHKPSGRLILLVPAGWSLWLTPDAPPLAGLVSLIVVGGLMVSGAGCIANDLWDRRIDRQVERT
RERPLAKGSIRISTAVGLLIVLLLLSLLVVVSLPTPSRGLCLALAILALPPILLYPSAKRWFAYPQAVLALCWGFAVLIP
WAASQANLNGGWPLLGCWLATLMWTFGFDTVYAMADRRDDANLALKSSALSLGSHALKTVAFSYALACTFLASAAMSAGV
GWAFWPFWLIASIGMQKETWTLRGSNQPMTTYGQHFQHQVLLGAMLLLGLILGRIS

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate [H]

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI260656052, Length=295, Percent_Identity=29.8305084745763, Blast_Score=113, Evalue=2e-25,
Organism=Escherichia coli, GI1790473, Length=288, Percent_Identity=31.25, Blast_Score=126, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17553718, Length=213, Percent_Identity=34.7417840375587, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI32565247, Length=213, Percent_Identity=34.2723004694836, Blast_Score=107, Evalue=9e-24,
Organism=Caenorhabditis elegans, GI17553720, Length=188, Percent_Identity=33.5106382978723, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI32565245, Length=144, Percent_Identity=37.5, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI32565243, Length=144, Percent_Identity=37.5, Blast_Score=71, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6324370, Length=248, Percent_Identity=31.0483870967742, Blast_Score=114, Evalue=2e-26,
Organism=Drosophila melanogaster, GI21355567, Length=291, Percent_Identity=32.3024054982818, Blast_Score=130, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006370
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.-

Molecular weight: Translated: 32331; Mature: 32200

Theoretical pI: Translated: 10.38; Mature: 10.38

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSRSVSNGLRQWLELLRWHKPSGRLILLVPAGWSLWLTPDAPPLAGLVSLIVVGGLMVS
CCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCEEEECCCCCHHHHHHHHHHHHHHHHC
GAGCIANDLWDRRIDRQVERTRERPLAKGSIRISTAVGLLIVLLLLSLLVVVSLPTPSRG
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCCH
LCLALAILALPPILLYPSAKRWFAYPQAVLALCWGFAVLIPWAASQANLNGGWPLLGCWL
HHHHHHHHHHCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
ATLMWTFGFDTVYAMADRRDDANLALKSSALSLGSHALKTVAFSYALACTFLASAAMSAG
HHHHHHHCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VGWAFWPFWLIASIGMQKETWTLRGSNQPMTTYGQHFQHQVLLGAMLLLGLILGRIS
CCHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TSRSVSNGLRQWLELLRWHKPSGRLILLVPAGWSLWLTPDAPPLAGLVSLIVVGGLMVS
CCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCEEEECCCCCHHHHHHHHHHHHHHHHC
GAGCIANDLWDRRIDRQVERTRERPLAKGSIRISTAVGLLIVLLLLSLLVVVSLPTPSRG
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCCH
LCLALAILALPPILLYPSAKRWFAYPQAVLALCWGFAVLIPWAASQANLNGGWPLLGCWL
HHHHHHHHHHCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
ATLMWTFGFDTVYAMADRRDDANLALKSSALSLGSHALKTVAFSYALACTFLASAAMSAG
HHHHHHHCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VGWAFWPFWLIASIGMQKETWTLRGSNQPMTTYGQHFQHQVLLGAMLLLGLILGRIS
CCHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA