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The map label for this gene is rfbB [C]

Identifier: 124021826

GI number: 124021826

Start: 113251

End: 114258

Strand: Reverse

Name: rfbB [C]

Synonym: P9303_01131

Alternate gene names: 124021826

Gene position: 114258-113251 (Counterclockwise)

Preceding gene: 124021827

Following gene: 124021825

Centisome position: 4.26

GC content: 38.99

Gene sequence:

>1008_bases
ATGACTAAGCAATCGTTAGCCTTGGTCACCGGTGCTGATGGCTTTATTGGATCACATTTGGTTGAATATCTATTAAATAA
AGGTTGCAATGTAAGGGCTTTTTGCTTATACAACTCTAATGGAAGCTGGGGTTGGTTGGATAGAATTGATAAGGAGTATA
AAAAAAATATTGAGGTGGTATTGGGAGACATTAGAGATCCAATATGCGTAAAAAATGCGTTGAAAGGTTGCGACCATGTA
TATCATTTGGCGGCATTAATAGCAATTCCTTATAGCTACATGGCCCCAGCTAGTTATGTGGAAACGAATATAATGGGAAC
TCTAAATGTAATTCAGGCGGCAAGAGAGTTAGATGTAAGTAAAGTAGTTCATACTTCAACATCTGAGACATATGGAACAG
CACAATTTGTACCAATTACTGAGGATCATCCATTGGTGGCGCAGTCTCCCTATGCGGCGAGTAAAATCGGAGCTGATCAA
ATAGCCTTGAGCTATTGGAGAAGTTTTGAAACACCAGTATCAGTGATTAGACCGTTTAACACATATGGTCCAAGGCAAAG
TTGCCGTGCTGTAATACCAACAATTATTACACAAATCGCAGGTGGAGAAAAAAGAATCAAGCTAGGTTCGACTACTCCGA
CTAGAGATTTCAATTTCATATTAGATACTTGTTCTGCTTTTTATGAAGTTGGAAAATCAGAGGCCTGTGTAGGTCAAGTA
GTTAATGCAGCTAGTAATTACGAAATATCAATTGGAGAAACTGTGAGCCTGATTGCTGATGCTATGGGTGCAAGAGTTGA
GATATCTAGCGAAGCTGAAAGGGTTAGGCCTGAAAGATCTGAAGTGAATAGACTCTTTGGTGACAATAGTCGCATAAAGC
GTTTAACAGAATGGCGCCCAAAATATGACGGTAAGGATGGTTTTAAAAGAGGGATCGCTCGTACAGTTGAATGGTTTACA
AAGCCAAATAATCTTGCATTATATAAACTTGGTCAATATTCCATATGA

Upstream 100 bases:

>100_bases
AGAGTGAAGATGTAGCTCATACTATAATATTCTTATTATCCAGTGCAGCATTTGCAATCAATGGCCAGAATATTATTATT
GACGATGGATGGGTACTTTA

Downstream 100 bases:

>100_bases
AAAGTTTAGCCATTGAAATCGTAAATGCAATTGAGAAGGTTATTGGACCTGCTAGTAAAGATAATAAAATCTCGTTACAT
GAACCTGATTTTAACAAGAC

Product: nucleoside-diphosphate-sugar epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MTKQSLALVTGADGFIGSHLVEYLLNKGCNVRAFCLYNSNGSWGWLDRIDKEYKKNIEVVLGDIRDPICVKNALKGCDHV
YHLAALIAIPYSYMAPASYVETNIMGTLNVIQAARELDVSKVVHTSTSETYGTAQFVPITEDHPLVAQSPYAASKIGADQ
IALSYWRSFETPVSVIRPFNTYGPRQSCRAVIPTIITQIAGGEKRIKLGSTTPTRDFNFILDTCSAFYEVGKSEACVGQV
VNAASNYEISIGETVSLIADAMGARVEISSEAERVRPERSEVNRLFGDNSRIKRLTEWRPKYDGKDGFKRGIARTVEWFT
KPNNLALYKLGQYSI

Sequences:

>Translated_335_residues
MTKQSLALVTGADGFIGSHLVEYLLNKGCNVRAFCLYNSNGSWGWLDRIDKEYKKNIEVVLGDIRDPICVKNALKGCDHV
YHLAALIAIPYSYMAPASYVETNIMGTLNVIQAARELDVSKVVHTSTSETYGTAQFVPITEDHPLVAQSPYAASKIGADQ
IALSYWRSFETPVSVIRPFNTYGPRQSCRAVIPTIITQIAGGEKRIKLGSTTPTRDFNFILDTCSAFYEVGKSEACVGQV
VNAASNYEISIGETVSLIADAMGARVEISSEAERVRPERSEVNRLFGDNSRIKRLTEWRPKYDGKDGFKRGIARTVEWFT
KPNNLALYKLGQYSI
>Mature_334_residues
TKQSLALVTGADGFIGSHLVEYLLNKGCNVRAFCLYNSNGSWGWLDRIDKEYKKNIEVVLGDIRDPICVKNALKGCDHVY
HLAALIAIPYSYMAPASYVETNIMGTLNVIQAARELDVSKVVHTSTSETYGTAQFVPITEDHPLVAQSPYAASKIGADQI
ALSYWRSFETPVSVIRPFNTYGPRQSCRAVIPTIITQIAGGEKRIKLGSTTPTRDFNFILDTCSAFYEVGKSEACVGQVV
NAASNYEISIGETVSLIADAMGARVEISSEAERVRPERSEVNRLFGDNSRIKRLTEWRPKYDGKDGFKRGIARTVEWFTK
PNNLALYKLGQYSI

Specific function: DTDP-L-RHAMNOSE BIOSYNTHESIS WITHIN THE O ANTIGEN BIOSYNTHESIS PATHWAY OF LIPOPOLYSACCHARIDE BIOSYNTHESIS. [C]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI7657641, Length=320, Percent_Identity=30.9375, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI42516563, Length=317, Percent_Identity=27.7602523659306, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI4504031, Length=352, Percent_Identity=25, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI56237023, Length=295, Percent_Identity=24.7457627118644, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI56118217, Length=295, Percent_Identity=24.7457627118644, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI189083684, Length=295, Percent_Identity=24.7457627118644, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI193211614, Length=219, Percent_Identity=28.310502283105, Blast_Score=66, Evalue=6e-11,
Organism=Homo sapiens, GI8393516, Length=219, Percent_Identity=28.310502283105, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI1788353, Length=354, Percent_Identity=29.6610169491525, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI48994969, Length=338, Percent_Identity=27.5147928994083, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1788366, Length=354, Percent_Identity=25.4237288135593, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1786974, Length=319, Percent_Identity=26.6457680250784, Blast_Score=81, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17568069, Length=329, Percent_Identity=26.4437689969605, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17539532, Length=322, Percent_Identity=26.0869565217391, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17539422, Length=353, Percent_Identity=23.7960339943343, Blast_Score=88, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI133901786, Length=353, Percent_Identity=23.7960339943343, Blast_Score=88, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI133901788, Length=353, Percent_Identity=23.7960339943343, Blast_Score=88, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI133901790, Length=353, Percent_Identity=23.7960339943343, Blast_Score=88, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17539424, Length=353, Percent_Identity=23.7960339943343, Blast_Score=88, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17507723, Length=347, Percent_Identity=23.6311239193084, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71982038, Length=347, Percent_Identity=25.3602305475504, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71982035, Length=345, Percent_Identity=25.5072463768116, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI115532424, Length=327, Percent_Identity=24.7706422018349, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71987463, Length=193, Percent_Identity=32.6424870466321, Blast_Score=80, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6319493, Length=244, Percent_Identity=29.0983606557377, Blast_Score=76, Evalue=7e-15,
Organism=Drosophila melanogaster, GI21356223, Length=330, Percent_Identity=29.3939393939394, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI19923002, Length=239, Percent_Identity=31.7991631799163, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24158427, Length=337, Percent_Identity=25.2225519287834, Blast_Score=76, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 37130; Mature: 36998

Theoretical pI: Translated: 8.25; Mature: 8.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKQSLALVTGADGFIGSHLVEYLLNKGCNVRAFCLYNSNGSWGWLDRIDKEYKKNIEVV
CCCCCEEEEECCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHCCHHEE
LGDIRDPICVKNALKGCDHVYHLAALIAIPYSYMAPASYVETNIMGTLNVIQAARELDVS
EECCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCHHHHHHHHHHHHHHHHHHHHCCHH
KVVHTSTSETYGTAQFVPITEDHPLVAQSPYAASKIGADQIALSYWRSFETPVSVIRPFN
HHHHCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHCCHHHHHHHHHHCCCCCHHHHCCCC
TYGPRQSCRAVIPTIITQIAGGEKRIKLGSTTPTRDFNFILDTCSAFYEVGKSEACVGQV
CCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHH
VNAASNYEISIGETVSLIADAMGARVEISSEAERVRPERSEVNRLFGDNSRIKRLTEWRP
HHCCCCCEEECCHHHHHHHHHHCCEEEECCHHHHHCCCHHHHHHHHCCCHHHHHHHHCCC
KYDGKDGFKRGIARTVEWFTKPNNLALYKLGQYSI
CCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCC
>Mature Secondary Structure 
TKQSLALVTGADGFIGSHLVEYLLNKGCNVRAFCLYNSNGSWGWLDRIDKEYKKNIEVV
CCCCEEEEECCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHCCHHEE
LGDIRDPICVKNALKGCDHVYHLAALIAIPYSYMAPASYVETNIMGTLNVIQAARELDVS
EECCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCHHHHHHHHHHHHHHHHHHHHCCHH
KVVHTSTSETYGTAQFVPITEDHPLVAQSPYAASKIGADQIALSYWRSFETPVSVIRPFN
HHHHCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHCCHHHHHHHHHHCCCCCHHHHCCCC
TYGPRQSCRAVIPTIITQIAGGEKRIKLGSTTPTRDFNFILDTCSAFYEVGKSEACVGQV
CCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHH
VNAASNYEISIGETVSLIADAMGARVEISSEAERVRPERSEVNRLFGDNSRIKRLTEWRP
HHCCCCCEEECCHHHHHHHHHHCCEEEECCHHHHHCCCHHHHHHHHCCCHHHHHHHHCCC
KYDGKDGFKRGIARTVEWFTKPNNLALYKLGQYSI
CCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]