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The map label for this gene is pheS [H]

Identifier: 123969001

GI number: 123969001

Start: 1253594

End: 1254625

Strand: Reverse

Name: pheS [H]

Synonym: A9601_14691

Alternate gene names: 123969001

Gene position: 1254625-1253594 (Counterclockwise)

Preceding gene: 123969003

Following gene: 123969000

Centisome position: 75.13

GC content: 32.95

Gene sequence:

>1032_bases
GTGATACTTATTTTTACTATATCAGTGAGTCAAATTGAATCATTAAGTCAAATTGAGGGAAAACTAAATAATCTTTCTCT
TGCAGCAAAAAAAAATATAGATAATCTTAATACCCATGAAGAGCTAGATCAATTAAAAGTTTCTTTGCTAGGAAAAAAAG
GTGATTTGTCAGTTATCTTGAAAACAATGGGGCAATTATCTGCTACTGATAGGCCAATTGTTGGCCAGAAGGCAAACTTA
ATAAAGATAAATTTGCAAGAATTAATAACTGAAAAGAAAAACCAACTAAATAGTGAAGCTTTAGATAAAAAGATTAAAAC
AGAAAAAATTGATGTAACTATTCCTGCAATTGGAACACCACCAGGAAAAAAACATCCTTTAATATCAACTCAAGATGAAA
TAATAGATATTTTTTGTGGTTTAGGATACTCAGTAGAAAGTGGTCCTGAAATAGAAACTGATTTTTATAATTTTGAGTCT
CTCAACATACCCAAGAATCACCCAGCAAGAGATATGCAGGATACTTTCTACTTAGATGAAAATCAACTTTTGAGGACCCA
TACTTCACCTGTTCAGATAAGGTACTTAGAGAATAATCCTCCTCCAGTAAGAATAATTGCTCCCGGGAGAGTATATAGGA
GAGATGCAGTAGATGCTACTCATTCCCCTGTATTTAATCAGGTTGAGGTTTTATGTATCGATCAAGACATTAATTTTAGT
CATTTAAGAGGAACAGTTCTTACATTTTTAAAAGCCTTTTTTGGAGATATTCCTGTAAGATTTAGAGCTAGTTATTTCCC
ATTTACTGAACCTTCAGCAGAAGTAGACGTCCAGTGGAAAGGTAAATGGTTAGAAGTAATGGGTTGCGGAATGGTTGATC
CAAAGGTCTTAGAAAAATTAGGAATTGATTCTGAGAAATGGACTGGTTTTGCAGCAGGATTAGGAGTTGAGAGATTTTGT
ATGGTTAGACATCAGATCGATGACATCCGAAAATTTTATACAAATGATATTAGATTCTTAGAACAGTTCTAA

Upstream 100 bases:

>100_bases
ATCCCTGCAGCAAAAACACCATCATCATTGCTAATTAATATATTTAACGGTTTCATTAATCAATGCATTTTATTTATGGA
CAATATTTAAGTAAGATAAA

Downstream 100 bases:

>100_bases
TAGTATTTAATTTTTAAATTAGGATTGTCCAACAAATTAGTTTAAGATAGTCCTAGTTTTAATTTTTTGATTGGTACGTA
AAGCAGGACTAATCGTTAAT

Product: phenylalanyl-tRNA synthetase subunit alpha

Products: NA

Alternate protein names: Phenylalanine--tRNA ligase alpha chain; PheRS [H]

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MILIFTISVSQIESLSQIEGKLNNLSLAAKKNIDNLNTHEELDQLKVSLLGKKGDLSVILKTMGQLSATDRPIVGQKANL
IKINLQELITEKKNQLNSEALDKKIKTEKIDVTIPAIGTPPGKKHPLISTQDEIIDIFCGLGYSVESGPEIETDFYNFES
LNIPKNHPARDMQDTFYLDENQLLRTHTSPVQIRYLENNPPPVRIIAPGRVYRRDAVDATHSPVFNQVEVLCIDQDINFS
HLRGTVLTFLKAFFGDIPVRFRASYFPFTEPSAEVDVQWKGKWLEVMGCGMVDPKVLEKLGIDSEKWTGFAAGLGVERFC
MVRHQIDDIRKFYTNDIRFLEQF

Sequences:

>Translated_343_residues
MILIFTISVSQIESLSQIEGKLNNLSLAAKKNIDNLNTHEELDQLKVSLLGKKGDLSVILKTMGQLSATDRPIVGQKANL
IKINLQELITEKKNQLNSEALDKKIKTEKIDVTIPAIGTPPGKKHPLISTQDEIIDIFCGLGYSVESGPEIETDFYNFES
LNIPKNHPARDMQDTFYLDENQLLRTHTSPVQIRYLENNPPPVRIIAPGRVYRRDAVDATHSPVFNQVEVLCIDQDINFS
HLRGTVLTFLKAFFGDIPVRFRASYFPFTEPSAEVDVQWKGKWLEVMGCGMVDPKVLEKLGIDSEKWTGFAAGLGVERFC
MVRHQIDDIRKFYTNDIRFLEQF
>Mature_343_residues
MILIFTISVSQIESLSQIEGKLNNLSLAAKKNIDNLNTHEELDQLKVSLLGKKGDLSVILKTMGQLSATDRPIVGQKANL
IKINLQELITEKKNQLNSEALDKKIKTEKIDVTIPAIGTPPGKKHPLISTQDEIIDIFCGLGYSVESGPEIETDFYNFES
LNIPKNHPARDMQDTFYLDENQLLRTHTSPVQIRYLENNPPPVRIIAPGRVYRRDAVDATHSPVFNQVEVLCIDQDINFS
HLRGTVLTFLKAFFGDIPVRFRASYFPFTEPSAEVDVQWKGKWLEVMGCGMVDPKVLEKLGIDSEKWTGFAAGLGVERFC
MVRHQIDDIRKFYTNDIRFLEQF

Specific function: Unknown

COG id: COG0016

COG function: function code J; Phenylalanyl-tRNA synthetase alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha chain type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI5729820, Length=229, Percent_Identity=33.1877729257642, Blast_Score=136, Evalue=4e-32,
Organism=Homo sapiens, GI4758340, Length=263, Percent_Identity=30.7984790874525, Blast_Score=120, Evalue=2e-27,
Organism=Escherichia coli, GI1788007, Length=324, Percent_Identity=49.0740740740741, Blast_Score=324, Evalue=6e-90,
Organism=Caenorhabditis elegans, GI32566635, Length=265, Percent_Identity=33.9622641509434, Blast_Score=134, Evalue=7e-32,
Organism=Caenorhabditis elegans, GI32563657, Length=271, Percent_Identity=29.1512915129151, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17508957, Length=271, Percent_Identity=29.1512915129151, Blast_Score=125, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6321087, Length=298, Percent_Identity=29.8657718120805, Blast_Score=138, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6325304, Length=88, Percent_Identity=42.0454545454545, Blast_Score=87, Evalue=5e-18,
Organism=Drosophila melanogaster, GI17137424, Length=277, Percent_Identity=29.2418772563177, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI18858079, Length=265, Percent_Identity=31.3207547169811, Blast_Score=119, Evalue=2e-27,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006195
- InterPro:   IPR004529
- InterPro:   IPR004188
- InterPro:   IPR022911
- InterPro:   IPR002319
- InterPro:   IPR010978 [H]

Pfam domain/function: PF02912 Phe_tRNA-synt_N; PF01409 tRNA-synt_2d [H]

EC number: =6.1.1.20 [H]

Molecular weight: Translated: 38863; Mature: 38863

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILIFTISVSQIESLSQIEGKLNNLSLAAKKNIDNLNTHEELDQLKVSLLGKKGDLSVIL
CEEEEEECHHHHHHHHHHHHHHHCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCHHHHH
KTMGQLSATDRPIVGQKANLIKINLQELITEKKNQLNSEALDKKIKTEKIDVTIPAIGTP
HHHHHCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHCCHHHHHHHHCCCEEEEEECCCCCC
PGKKHPLISTQDEIIDIFCGLGYSVESGPEIETDFYNFESLNIPKNHPARDMQDTFYLDE
CCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCEECCEECCCCCCCCCCCCCCEEEECC
NQLLRTHTSPVQIRYLENNPPPVRIIAPGRVYRRDAVDATHSPVFNQVEVLCIDQDINFS
CCCEEECCCCEEEEEECCCCCCEEEECCCCHHHHHCCCCCCCCCCCCEEEEEEECCCCHH
HLRGTVLTFLKAFFGDIPVRFRASYFPFTEPSAEVDVQWKGKWLEVMGCGMVDPKVLEKL
HHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCEEEEECCCEEEEECCCCCCHHHHHHH
GIDSEKWTGFAAGLGVERFCMVRHQIDDIRKFYTNDIRFLEQF
CCCCHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MILIFTISVSQIESLSQIEGKLNNLSLAAKKNIDNLNTHEELDQLKVSLLGKKGDLSVIL
CEEEEEECHHHHHHHHHHHHHHHCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCHHHHH
KTMGQLSATDRPIVGQKANLIKINLQELITEKKNQLNSEALDKKIKTEKIDVTIPAIGTP
HHHHHCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHCCHHHHHHHHCCCEEEEEECCCCCC
PGKKHPLISTQDEIIDIFCGLGYSVESGPEIETDFYNFESLNIPKNHPARDMQDTFYLDE
CCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCEECCEECCCCCCCCCCCCCCEEEECC
NQLLRTHTSPVQIRYLENNPPPVRIIAPGRVYRRDAVDATHSPVFNQVEVLCIDQDINFS
CCCEEECCCCEEEEEECCCCCCEEEECCCCHHHHHCCCCCCCCCCCCEEEEEEECCCCHH
HLRGTVLTFLKAFFGDIPVRFRASYFPFTEPSAEVDVQWKGKWLEVMGCGMVDPKVLEKL
HHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCEEEEECCCEEEEECCCCCCHHHHHHH
GIDSEKWTGFAAGLGVERFCMVRHQIDDIRKFYTNDIRFLEQF
CCCCHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA