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The map label for this gene is ppnK [H]

Identifier: 123969000

GI number: 123969000

Start: 1252615

End: 1253523

Strand: Reverse

Name: ppnK [H]

Synonym: A9601_14681

Alternate gene names: 123969000

Gene position: 1253523-1252615 (Counterclockwise)

Preceding gene: 123969001

Following gene: 123968998

Centisome position: 75.07

GC content: 38.83

Gene sequence:

>909_bases
TTGGTACGTAAAGCAGGACTAATCGTTAATGATGGAAAGGAACTAGCTGTTCAAACTGCAACTTCTGTTCAAAAAAAATT
GGAAAAATCTAATTTTGAAGTTGTAAGAGTTAGTAGCTCCGGAGGGATGGTTGGTTTCGCAAATCCTGATCAACATGTAC
GTCCCTTGGGATATACGAATTGTGTCCCTGAGGGGTTTGACTCATCAATGGAATTCGCAATTGTTCTTGGCGGAGATGGG
ACTGTACTTTCTGCTGCAAGGCAAACGGCACCTGCTAAAGTTCCAATTCTTACAATAAATACTGGTCATTTAGGATTTCT
TGCGGAAGCTTACTTATCTAACCTAGATGAGGCTATAGATAAAATAATTGCTGGAAATTGGGATATTGAAGAAAGAACTT
GCTTTATCATTAGCGTAATGAGGAATGATCAGAGGAGATGGGAGTCTCTTTGCCTTAATGAGATGGCTCTTCATAGAGAA
CCTCTAACAAGTATGTGTCACTTTGAAATTTCTATAGGTCGACATGCTCCTGTGGATATTTCAGCTGATGGAGTAATTTT
ATCTACTCCAACTGGTTCTACCGCCTATTCTCTAAGTGCTGGAGGACCAGTTATCACACCTGATTGTCCAGTCGTGCAAT
TAACTCCAATTGCTCCACATTCATTGGCATCTAGGGCATTGGTTTTTAATGATTCAGAGCCAGTAACTGTTTTTCCTGCA
ACTCCTGAAAGATTAGTAATGGTTGTTGATGGCAATGCTGGTTGTTATGTTTGGCCTGAAGATAGGGTTTTAATAAGAAA
AAGTAAACACTCAGTAAAATTTATTAGACTTGAAGATCACGAATTTTTCCAAGTTTTAAGAAATAAACTTGGTTGGGGTT
TACCCCATGTGGCTAAACCTGAAAAATAA

Upstream 100 bases:

>100_bases
AATGATATTAGATTCTTAGAACAGTTCTAATAGTATTTAATTTTTAAATTAGGATTGTCCAACAAATTAGTTTAAGATAG
TCCTAGTTTTAATTTTTTGA

Downstream 100 bases:

>100_bases
CAATTATTTGAATTTATTTTTTCCCTGTTAATAGAAAAACAGGATTATTTGGTTCTAGTCTCATTCCCTCCGCAATACTT
AAGCTTTTATAGGTCTGAAT

Product: inorganic polyphosphate/ATP-NAD kinase

Products: NA

Alternate protein names: Poly(P)/ATP NAD kinase 2 [H]

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MVRKAGLIVNDGKELAVQTATSVQKKLEKSNFEVVRVSSSGGMVGFANPDQHVRPLGYTNCVPEGFDSSMEFAIVLGGDG
TVLSAARQTAPAKVPILTINTGHLGFLAEAYLSNLDEAIDKIIAGNWDIEERTCFIISVMRNDQRRWESLCLNEMALHRE
PLTSMCHFEISIGRHAPVDISADGVILSTPTGSTAYSLSAGGPVITPDCPVVQLTPIAPHSLASRALVFNDSEPVTVFPA
TPERLVMVVDGNAGCYVWPEDRVLIRKSKHSVKFIRLEDHEFFQVLRNKLGWGLPHVAKPEK

Sequences:

>Translated_302_residues
MVRKAGLIVNDGKELAVQTATSVQKKLEKSNFEVVRVSSSGGMVGFANPDQHVRPLGYTNCVPEGFDSSMEFAIVLGGDG
TVLSAARQTAPAKVPILTINTGHLGFLAEAYLSNLDEAIDKIIAGNWDIEERTCFIISVMRNDQRRWESLCLNEMALHRE
PLTSMCHFEISIGRHAPVDISADGVILSTPTGSTAYSLSAGGPVITPDCPVVQLTPIAPHSLASRALVFNDSEPVTVFPA
TPERLVMVVDGNAGCYVWPEDRVLIRKSKHSVKFIRLEDHEFFQVLRNKLGWGLPHVAKPEK
>Mature_302_residues
MVRKAGLIVNDGKELAVQTATSVQKKLEKSNFEVVRVSSSGGMVGFANPDQHVRPLGYTNCVPEGFDSSMEFAIVLGGDG
TVLSAARQTAPAKVPILTINTGHLGFLAEAYLSNLDEAIDKIIAGNWDIEERTCFIISVMRNDQRRWESLCLNEMALHRE
PLTSMCHFEISIGRHAPVDISADGVILSTPTGSTAYSLSAGGPVITPDCPVVQLTPIAPHSLASRALVFNDSEPVTVFPA
TPERLVMVVDGNAGCYVWPEDRVLIRKSKHSVKFIRLEDHEFFQVLRNKLGWGLPHVAKPEK

Specific function: Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus [H]

COG id: COG0061

COG function: function code G; Predicted sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD kinase family [H]

Homologues:

Organism=Homo sapiens, GI55743112, Length=261, Percent_Identity=26.0536398467433, Blast_Score=78, Evalue=8e-15,
Organism=Escherichia coli, GI1788968, Length=223, Percent_Identity=35.4260089686099, Blast_Score=148, Evalue=4e-37,
Organism=Saccharomyces cerevisiae, GI6320794, Length=251, Percent_Identity=31.4741035856574, Blast_Score=109, Evalue=4e-25,
Organism=Saccharomyces cerevisiae, GI6325068, Length=169, Percent_Identity=32.5443786982249, Blast_Score=91, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6322509, Length=250, Percent_Identity=26.8, Blast_Score=88, Evalue=2e-18,
Organism=Drosophila melanogaster, GI28573828, Length=247, Percent_Identity=27.1255060728745, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI28573830, Length=247, Percent_Identity=27.1255060728745, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI28573832, Length=247, Percent_Identity=27.1255060728745, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI161077047, Length=247, Percent_Identity=27.1255060728745, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI28573826, Length=247, Percent_Identity=27.1255060728745, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24653424, Length=202, Percent_Identity=28.7128712871287, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI281363321, Length=202, Percent_Identity=28.7128712871287, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI281363323, Length=202, Percent_Identity=28.7128712871287, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI20129957, Length=202, Percent_Identity=28.7128712871287, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24653422, Length=202, Percent_Identity=28.7128712871287, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016064
- InterPro:   IPR017438
- InterPro:   IPR017437
- InterPro:   IPR002504 [H]

Pfam domain/function: PF01513 NAD_kinase [H]

EC number: =2.7.1.23 [H]

Molecular weight: Translated: 32944; Mature: 32944

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRKAGLIVNDGKELAVQTATSVQKKLEKSNFEVVRVSSSGGMVGFANPDQHVRPLGYTN
CCCCCCEEEECCHHEEEEHHHHHHHHHHCCCCEEEEEECCCCEEEECCCCCCCCCCCCCC
CVPEGFDSSMEFAIVLGGDGTVLSAARQTAPAKVPILTINTGHLGFLAEAYLSNLDEAID
CCCCCCCCCCEEEEEECCCCCEEHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHH
KIIAGNWDIEERTCFIISVMRNDQRRWESLCLNEMALHREPLTSMCHFEISIGRHAPVDI
HHHCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCEE
SADGVILSTPTGSTAYSLSAGGPVITPDCPVVQLTPIAPHSLASRALVFNDSEPVTVFPA
CCCCEEEECCCCCCEEEECCCCCEECCCCCEEEEECCCCHHHHCEEEEECCCCCEEEEEC
TPERLVMVVDGNAGCYVWPEDRVLIRKSKHSVKFIRLEDHEFFQVLRNKLGWGLPHVAKP
CCCEEEEEEECCCCEEECCCCCEEEEECCCCEEEEEECCHHHHHHHHHHHCCCCCCCCCC
EK
CC
>Mature Secondary Structure
MVRKAGLIVNDGKELAVQTATSVQKKLEKSNFEVVRVSSSGGMVGFANPDQHVRPLGYTN
CCCCCCEEEECCHHEEEEHHHHHHHHHHCCCCEEEEEECCCCEEEECCCCCCCCCCCCCC
CVPEGFDSSMEFAIVLGGDGTVLSAARQTAPAKVPILTINTGHLGFLAEAYLSNLDEAID
CCCCCCCCCCEEEEEECCCCCEEHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHH
KIIAGNWDIEERTCFIISVMRNDQRRWESLCLNEMALHREPLTSMCHFEISIGRHAPVDI
HHHCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCEE
SADGVILSTPTGSTAYSLSAGGPVITPDCPVVQLTPIAPHSLASRALVFNDSEPVTVFPA
CCCCEEEECCCCCCEEEECCCCCEECCCCCEEEEECCCCHHHHCEEEEECCCCCEEEEEC
TPERLVMVVDGNAGCYVWPEDRVLIRKSKHSVKFIRLEDHEFFQVLRNKLGWGLPHVAKP
CCCEEEEEEECCCCEEECCCCCEEEEECCCCEEEEEECCHHHHHHHHHHHCCCCCCCCCC
EK
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA