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The map label for this gene is gmhB [H]

Identifier: 123968971

GI number: 123968971

Start: 1224588

End: 1225268

Strand: Direct

Name: gmhB [H]

Synonym: A9601_14391

Alternate gene names: 123968971

Gene position: 1224588-1225268 (Clockwise)

Preceding gene: 123968970

Following gene: 123968972

Centisome position: 73.33

GC content: 27.31

Gene sequence:

>681_bases
ATGATATTAAAGATTAATAAGCTTATTGAAAATAGCAATTTAGTAAATTTCTTTTATGAAAATAGGGTCTTTCAATCAAA
AGACAATTTAAAGAGATCAGCAATTTTTCTAGATCGAGATGGAGTAATTATTAAGGACAAACACTTTATTTCTAATGGTA
AAGATGTTGAATTGGAATATGGGGTGCCTAGTCTTTTTAAATTATCAAATACTCTAAATATCCCAATAATTATAATTACA
AATCAATCTGGCATTTCAAGAGGATTTTTTACGTGGGAGGATTATATGGATGTTACGAAAGCAATGTTAAATAAAGTTAA
AGTAAGTAATACATTAATTGCTATTTACGCTAATGGATTAGGTCCGAATGCACCATCTTTTTCATGGAGGAAGCCTAGTC
CTAATATGATTCTCAATGCATCTTTAACTCTTGATATTGACTTAAAAAAATCATTAATTATTGGGGATAGATTGTCAGAT
TTAATTGCAGGATTGGATGCAGGAATTTCAACTCTTATACACATAAAAACTGGACATGGTTTAAAAGAAAGAGACAAAGT
AAAAGAATACTTCAATATTATAAATCCACAAAATAATTTAGAGCCTATTTTTATTGATAATTTCTCAAATAAATCATTAA
AAATTATTGAAAACATTCTGAAAGACAATTGCTTAATGTAG

Upstream 100 bases:

>100_bases
AAATAATAAATAAATTACATTTTCTTTAAATATGTTAAAAATTATATAAAAATGAATATTAAATTAATAAACACTACTAT
TAAATTCTCATGATGAACAA

Downstream 100 bases:

>100_bases
GATTATTGAATGCCTTTATAAAATAAAATCTTTATTTTTTTAAATTATAGAATTTAAATTCTTTTATTAAAATTATTTAC
TTAAATTATTTTTAAAAAAT

Product: phosphatase

Products: NA

Alternate protein names: D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [H]

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MILKINKLIENSNLVNFFYENRVFQSKDNLKRSAIFLDRDGVIIKDKHFISNGKDVELEYGVPSLFKLSNTLNIPIIIIT
NQSGISRGFFTWEDYMDVTKAMLNKVKVSNTLIAIYANGLGPNAPSFSWRKPSPNMILNASLTLDIDLKKSLIIGDRLSD
LIAGLDAGISTLIHIKTGHGLKERDKVKEYFNIINPQNNLEPIFIDNFSNKSLKIIENILKDNCLM

Sequences:

>Translated_226_residues
MILKINKLIENSNLVNFFYENRVFQSKDNLKRSAIFLDRDGVIIKDKHFISNGKDVELEYGVPSLFKLSNTLNIPIIIIT
NQSGISRGFFTWEDYMDVTKAMLNKVKVSNTLIAIYANGLGPNAPSFSWRKPSPNMILNASLTLDIDLKKSLIIGDRLSD
LIAGLDAGISTLIHIKTGHGLKERDKVKEYFNIINPQNNLEPIFIDNFSNKSLKIIENILKDNCLM
>Mature_226_residues
MILKINKLIENSNLVNFFYENRVFQSKDNLKRSAIFLDRDGVIIKDKHFISNGKDVELEYGVPSLFKLSNTLNIPIIIIT
NQSGISRGFFTWEDYMDVTKAMLNKVKVSNTLIAIYANGLGPNAPSFSWRKPSPNMILNASLTLDIDLKKSLIIGDRLSD
LIAGLDAGISTLIHIKTGHGLKERDKVKEYFNIINPQNNLEPIFIDNFSNKSLKIIENILKDNCLM

Specific function: Converts the D-glycero-beta-D-manno-heptose 1,7- bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1- phosphate by removing the phosphate group at the C-7 position [H]

COG id: COG0241

COG function: function code E; Histidinol phosphatase and related phosphatases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gmhB family [H]

Homologues:

Organism=Escherichia coli, GI1786399, Length=155, Percent_Identity=32.9032258064516, Blast_Score=79, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR006549
- InterPro:   IPR004446
- InterPro:   IPR006543
- InterPro:   IPR013954 [H]

Pfam domain/function: PF08645 PNK3P [H]

EC number: NA

Molecular weight: Translated: 25575; Mature: 25575

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILKINKLIENSNLVNFFYENRVFQSKDNLKRSAIFLDRDGVIIKDKHFISNGKDVELEY
CEEEEEEHHCCCCEEEEEECCCEECCCCCCCEEEEEEECCCEEEECCCCCCCCCEEEEEC
GVPSLFKLSNTLNIPIIIITNQSGISRGFFTWEDYMDVTKAMLNKVKVSNTLIAIYANGL
CCCHHEECCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEECCC
GPNAPSFSWRKPSPNMILNASLTLDIDLKKSLIIGDRLSDLIAGLDAGISTLIHIKTGHG
CCCCCCCCCCCCCCCEEEEEEEEEEEECCCEEEECHHHHHHHHHHCCCCEEEEEEECCCC
LKERDKVKEYFNIINPQNNLEPIFIDNFSNKSLKIIENILKDNCLM
CCHHHHHHHHHHHCCCCCCCCCEEEECCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MILKINKLIENSNLVNFFYENRVFQSKDNLKRSAIFLDRDGVIIKDKHFISNGKDVELEY
CEEEEEEHHCCCCEEEEEECCCEECCCCCCCEEEEEEECCCEEEECCCCCCCCCEEEEEC
GVPSLFKLSNTLNIPIIIITNQSGISRGFFTWEDYMDVTKAMLNKVKVSNTLIAIYANGL
CCCHHEECCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEECCC
GPNAPSFSWRKPSPNMILNASLTLDIDLKKSLIIGDRLSDLIAGLDAGISTLIHIKTGHG
CCCCCCCCCCCCCCCEEEEEEEEEEEECCCEEEECHHHHHHHHHHCCCCEEEEEEECCCC
LKERDKVKEYFNIINPQNNLEPIFIDNFSNKSLKIIENILKDNCLM
CCHHHHHHHHHHHCCCCCCCCCEEEECCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682; 12101286 [H]