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The map label for this gene is spsE

Identifier: 123968957

GI number: 123968957

Start: 1197212

End: 1198282

Strand: Reverse

Name: spsE

Synonym: A9601_14241

Alternate gene names: NA

Gene position: 1198282-1197212 (Counterclockwise)

Preceding gene: 123968958

Following gene: 123968956

Centisome position: 71.76

GC content: 29.32

Gene sequence:

>1071_bases
ATGTTAAAAAATCAAAATTTTGATAGTTATTCACGAATATTTAACAGGAAATTAGAAGAAGGAATAATTATTGCAGAAAT
AGGAGTTAATCATGGAGGAGATATTGATAAGGCAATCGCAATGATTGATGATGTAAAAAATAATGGAGGAGATGCGGTTA
AATTTCAGACTTACAAGGCAAATTTGATTGCAAGAAAAGATTCAAAAGCATATTGGGATACTACCAAAGAAAAAACAATG
TCTCAGTTTGAGCTTTTTTCTAAATATGACAAATTTGGTTTAGAAGAATTTAAGAAAATTGAGGATTATTGTAAAAGAAA
ATCGGTTCTATTTATGAGTACTCCATTTGACTCATATAGTGCAAATTATATTAATCAGTTAAGTAAGATACATAAGGTAG
CGAGTGTTGACATAACAAATCATATTTTAATTTCGCAATTAGCATCTTATGGAAAGGATATTATTTTATCCACGGGAGCC
TCAAATTTAGATGAGATTAAAGCTGCCGTAAGTTTAATAGAGTCTAAAAGTAAAATTTCTCCAGCACTTCTTCATTGTGT
AGTTAATTACCCTACATTAGATAAAGATGCTAATTTATTAAGAATAAAAAAACTCAAGGAAAGTTTTCCTGAAAATATTA
TTGGATATTCAGACCATACTCTGCCAGATAAAAATATGATTGTATGTACTCAAGCATATAATTATGGGGCTTTAATAATT
GAAAAACATTTCACATATGATAAGAAAATCCAAGGAAATGATCATTATCACAGCATGAATGCTAATGATTTAAAAATTCT
CAGAACTAATATTAGTAAAGCATACTCACTTCAAGGAAAGGGAAATATTAAACCTATGGAAAATGAGAAGTCTTCAATAT
TGCATGCTAGGAGAAGTTTGACTTCAAAATTTTTGATTAAGAAAGGATCGATACTTTCGAAAGAAATGATCATCCCAAAG
AGACCTGGCAATGGAATTTGCCCATCAAAAATTGAAGAAGTATTAGGGAGAAAGGTAAAAAAAGAAATAAAGGAAGATTC
TCCTATTAATTGGGAGGATTTAGAAATTTGA

Upstream 100 bases:

>100_bases
CTTTATCGATATAGAAAACATCCCGAAAGCCTAACAACTAATGATTTAGTTATGACTAAGTATGATCAAATTTTAGAAAA
AGATTATCCACAAAATTGAT

Downstream 100 bases:

>100_bases
AAAATTAATATTTTAATATTGTTAAATGATTTTTTTATTTTCCCAGAATTTAGAAGTAAAATAGTTTATGTGGTTAATAA
AAATATTTTTAAAAATTATT

Product: sialic acid synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MLKNQNFDSYSRIFNRKLEEGIIIAEIGVNHGGDIDKAIAMIDDVKNNGGDAVKFQTYKANLIARKDSKAYWDTTKEKTM
SQFELFSKYDKFGLEEFKKIEDYCKRKSVLFMSTPFDSYSANYINQLSKIHKVASVDITNHILISQLASYGKDIILSTGA
SNLDEIKAAVSLIESKSKISPALLHCVVNYPTLDKDANLLRIKKLKESFPENIIGYSDHTLPDKNMIVCTQAYNYGALII
EKHFTYDKKIQGNDHYHSMNANDLKILRTNISKAYSLQGKGNIKPMENEKSSILHARRSLTSKFLIKKGSILSKEMIIPK
RPGNGICPSKIEEVLGRKVKKEIKEDSPINWEDLEI

Sequences:

>Translated_356_residues
MLKNQNFDSYSRIFNRKLEEGIIIAEIGVNHGGDIDKAIAMIDDVKNNGGDAVKFQTYKANLIARKDSKAYWDTTKEKTM
SQFELFSKYDKFGLEEFKKIEDYCKRKSVLFMSTPFDSYSANYINQLSKIHKVASVDITNHILISQLASYGKDIILSTGA
SNLDEIKAAVSLIESKSKISPALLHCVVNYPTLDKDANLLRIKKLKESFPENIIGYSDHTLPDKNMIVCTQAYNYGALII
EKHFTYDKKIQGNDHYHSMNANDLKILRTNISKAYSLQGKGNIKPMENEKSSILHARRSLTSKFLIKKGSILSKEMIIPK
RPGNGICPSKIEEVLGRKVKKEIKEDSPINWEDLEI
>Mature_356_residues
MLKNQNFDSYSRIFNRKLEEGIIIAEIGVNHGGDIDKAIAMIDDVKNNGGDAVKFQTYKANLIARKDSKAYWDTTKEKTM
SQFELFSKYDKFGLEEFKKIEDYCKRKSVLFMSTPFDSYSANYINQLSKIHKVASVDITNHILISQLASYGKDIILSTGA
SNLDEIKAAVSLIESKSKISPALLHCVVNYPTLDKDANLLRIKKLKESFPENIIGYSDHTLPDKNMIVCTQAYNYGALII
EKHFTYDKKIQGNDHYHSMNANDLKILRTNISKAYSLQGKGNIKPMENEKSSILHARRSLTSKFLIKKGSILSKEMIIPK
RPGNGICPSKIEEVLGRKVKKEIKEDSPINWEDLEI

Specific function: Unknown

COG id: COG2089

COG function: function code M; Sialic acid synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To B.subtilis spsE [H]

Homologues:

Organism=Homo sapiens, GI12056473, Length=333, Percent_Identity=26.4264264264264, Blast_Score=128, Evalue=7e-30,
Organism=Drosophila melanogaster, GI21357081, Length=267, Percent_Identity=33.3333333333333, Blast_Score=129, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006190
- InterPro:   IPR013785
- InterPro:   IPR013132
- InterPro:   IPR013974 [H]

Pfam domain/function: PF03102 NeuB; PF08666 SAF [H]

EC number: NA

Molecular weight: Translated: 40400; Mature: 40400

Theoretical pI: Translated: 9.53; Mature: 9.53

Prosite motif: PS50844 AFP_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKNQNFDSYSRIFNRKLEEGIIIAEIGVNHGGDIDKAIAMIDDVKNNGGDAVKFQTYKA
CCCCCCCHHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCCEEEEEEEEE
NLIARKDSKAYWDTTKEKTMSQFELFSKYDKFGLEEFKKIEDYCKRKSVLFMSTPFDSYS
EEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCEEEEECCCCCCH
ANYINQLSKIHKVASVDITNHILISQLASYGKDIILSTGASNLDEIKAAVSLIESKSKIS
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHCCC
PALLHCVVNYPTLDKDANLLRIKKLKESFPENIIGYSDHTLPDKNMIVCTQAYNYGALII
HHHHHHHHCCCCCCCCCCHHHHHHHHHHCCHHHCCCCCCCCCCCCEEEEEECCCCCEEEE
EKHFTYDKKIQGNDHYHSMNANDLKILRTNISKAYSLQGKGNIKPMENEKSSILHARRSL
EECCCCCCEECCCCCEECCCCCCCEEEEEHHHHHEEECCCCCCCCCCCHHHHHHHHHHHH
TSKFLIKKGSILSKEMIIPKRPGNGICPSKIEEVLGRKVKKEIKEDSPINWEDLEI
HHHHHHHCCCCCHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MLKNQNFDSYSRIFNRKLEEGIIIAEIGVNHGGDIDKAIAMIDDVKNNGGDAVKFQTYKA
CCCCCCCHHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCCEEEEEEEEE
NLIARKDSKAYWDTTKEKTMSQFELFSKYDKFGLEEFKKIEDYCKRKSVLFMSTPFDSYS
EEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCEEEEECCCCCCH
ANYINQLSKIHKVASVDITNHILISQLASYGKDIILSTGASNLDEIKAAVSLIESKSKIS
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHCCC
PALLHCVVNYPTLDKDANLLRIKKLKESFPENIIGYSDHTLPDKNMIVCTQAYNYGALII
HHHHHHHHCCCCCCCCCCHHHHHHHHHHCCHHHCCCCCCCCCCCCEEEEEECCCCCEEEE
EKHFTYDKKIQGNDHYHSMNANDLKILRTNISKAYSLQGKGNIKPMENEKSSILHARRSL
EECCCCCCEECCCCCEECCCCCCCEEEEEHHHHHEEECCCCCCCCCCCHHHHHHHHHHHH
TSKFLIKKGSILSKEMIIPKRPGNGICPSKIEEVLGRKVKKEIKEDSPINWEDLEI
HHHHHHHCCCCCHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]