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The map label for this gene is zntA [H]

Identifier: 123967685

GI number: 123967685

Start: 137507

End: 139801

Strand: Reverse

Name: zntA [H]

Synonym: A9601_01481

Alternate gene names: 123967685

Gene position: 139801-137507 (Counterclockwise)

Preceding gene: 123967687

Following gene: 123967684

Centisome position: 8.37

GC content: 32.07

Gene sequence:

>2295_bases
ATGGAGAGCATTCAATTAAACATTACAGGAATGAAGTGCGGAGGTTGTGTTAGTACTGTTGAAAAAATATTGAATAATTC
TGACGGTATTGAAAATGTTTCTGTTAACTTGCTTACTGAAAGTGCATATTTTGAAATTACCCAGAATCATATAGAGATAG
AATCAGTTCTCGAAAATCTAAAAGAGAATGGTTTCCCATCAAAGATTTACATCAATGATTTTTCAAAAAAAATAAATAAA
TCAGAACTAGAAAAAAAAAAGAAATGGAATAATCAATGGAAAAAACTAACTTTTGCCCTATTACTTTTATTCTTTTCAGG
TTTAGGTCATCTAGCAGAAGGAAGATATATAAATTTTCCAATATTAGGTAATATATTATTTCACGCTTCATTAGCAACGT
TAGCTCTATTATTTCCTGGCAGAGGAATAATTATTAATGGATTTAAATCATTTATTAAGAACCATCCAGATATGGATTCT
TTAGTAGCCCTTGGAGTAATTAGCGCATATACAACAAGTCTTCTATCACTAATATTTCCTGCCACTGGTTTTCCTTGTTT
TTTTAATGAACCAGTTATGCTGTTAGGCTTCATACTAATTGGGCGTTTCTTAGAAGAAAGAGCAAGATATCAAACTGGTT
CATCCATTGGAGAATTATTAGATCTTCAACCAGAAATGGCAAATATCTACACAGAAGACAATCACATAAAGTCGATAAGA
GTAAATACTTTAAGACCTGATCAAGAGATTCAAGTTTTAGCAGGAGACAGAGTACCTGCTGACTGTATCGTTACACAAGG
TAATTCATATGTTGATGTTTCACATATTACTGGAGAATCCAAACCTATCGAGGTAAAAGAAGGCGAAATTCTATCTAGTG
GGTCTTTAAACCTTAATTCAACTCTCAGACTTAAAGTACAAAAGGTCGGAGGGGATTCTTCTCTTGCAAAACTAGTAAAT
CTTATTGAGTCTGTAAACGCAAGAAAACCTCGTATTCAAAGAGTTGCTGATGAAATTGCAGGCAAATTTACTTACTTTGT
ACTTATTTTTGCTACTTTAACCTTCTTCTTTTGGTGGAAGGGGGCAAGAAACATATGGCCAGATTTATTAAGTCATAATA
ATCAATTAATCACACATTCAAGCCACACACTTCATAGTTCGCTTGGTAGTAATGCTGAGAATTTCCTTAGTTTAGCAATT
CAATTGTCAATTGCTGTTTTAGTAATAGCTTGTCCTTGTGCCTTAGGTTTAGCAACCCCAACAGTAATAACTGTTGCATC
AGGTAAAGCAGCAAAAAAAGGAGTTTTATTTAAAGGAGGTGACAAAATAGAAATGGCTTCAAAAATTAATCATATTATTT
TTGACAAGACAGGTACTTTAACAAAAGGTAAGCCTTTCATTGTTGATTATAAAAATAATGATGATCATTCATTTTTATTA
AGAATAGCTGCCAGTTTAGAAAAGGAAAGCAGGCATCCAATCGCAGATGCCTTAATTCAAGAAGCAAAAAAACAAAATTT
AAGTTTATTTCCAATAAAAAAAATTTTCAATCATACAGGTAGAGGTATTTCTGGAGAACTAGAGTCAATTGATGGACTTA
TAAATATTGGAAATATTGAATGGCTAGTAAGTAAAGGAATAATTATTGATAGTGATGCAAAAAAAGTCATTGAAAATGAA
GAGACAAAAACGAACACCATCATTGGAGTCAGTATCAAAGATAAGTTATTAGGCTTTGTCTTCTTAGGAGACTTACTCAG
AGATGATTCAATTAAAACAGTTCAAAATTTAAGAGAAAACAAATTTAAAATTAATATTTTAAGTGGTGATAGGAAACAAA
CAGTTTTAGCTTTAGCAAAAAAAATTGGTTGTAAAGAAACAGAAGTAAAATGGGATCTTCTTCCTGAAATGAAGCTAAAG
ACTATAGAAAATTTAAAAATTAATAATAAAGTAGCAATGATTGGTGATGGAATTAATGATGTTCCAGCCTTAGCATCTTC
AGACCTAGGAATTGCGGTGGGATCAGGTACTCAAATAGCCAAGGCAAATGCAGATGTAGTATTGATGGGAGATCAACTTA
ATAGATTACCCTACGCCTTTAATCTTGCAAAAAATACTATAAGAAAAATAAAGCAAAATCTAACATGGGCTTTTGGTTAC
AACTTACTAGCTATCCCTTTAGCAGCGGGCATTTTATTCCCTAAATACGGTATTCTTCTTACTCCCTCAATAGCAGCATT
ATTGATGGCTATTAGTTCTATTACAGTTGTAATCAATGCTTTATCTTTGGATTGA

Upstream 100 bases:

>100_bases
AATATAGTAATTTAAAAAATAACTATTTAAAAAATCTATTACATTTATTATTATAGTTAAAAATAAGGTCAAGCATTAAC
TTGCTTTTAAAGTGAAAAAT

Downstream 100 bases:

>100_bases
ATGAAAGGAAAATTTATCGTTATTGAGGGTATTGATGGATGTGGTAAAACCACCCAAATAGATGAACTATCTAAGTGGCT
ACCCAACAGTGGTTTAATAA

Product: putative P-type ATPase transporter for copper

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 764; Mature: 764

Protein sequence:

>764_residues
MESIQLNITGMKCGGCVSTVEKILNNSDGIENVSVNLLTESAYFEITQNHIEIESVLENLKENGFPSKIYINDFSKKINK
SELEKKKKWNNQWKKLTFALLLLFFSGLGHLAEGRYINFPILGNILFHASLATLALLFPGRGIIINGFKSFIKNHPDMDS
LVALGVISAYTTSLLSLIFPATGFPCFFNEPVMLLGFILIGRFLEERARYQTGSSIGELLDLQPEMANIYTEDNHIKSIR
VNTLRPDQEIQVLAGDRVPADCIVTQGNSYVDVSHITGESKPIEVKEGEILSSGSLNLNSTLRLKVQKVGGDSSLAKLVN
LIESVNARKPRIQRVADEIAGKFTYFVLIFATLTFFFWWKGARNIWPDLLSHNNQLITHSSHTLHSSLGSNAENFLSLAI
QLSIAVLVIACPCALGLATPTVITVASGKAAKKGVLFKGGDKIEMASKINHIIFDKTGTLTKGKPFIVDYKNNDDHSFLL
RIAASLEKESRHPIADALIQEAKKQNLSLFPIKKIFNHTGRGISGELESIDGLINIGNIEWLVSKGIIIDSDAKKVIENE
ETKTNTIIGVSIKDKLLGFVFLGDLLRDDSIKTVQNLRENKFKINILSGDRKQTVLALAKKIGCKETEVKWDLLPEMKLK
TIENLKINNKVAMIGDGINDVPALASSDLGIAVGSGTQIAKANADVVLMGDQLNRLPYAFNLAKNTIRKIKQNLTWAFGY
NLLAIPLAAGILFPKYGILLTPSIAALLMAISSITVVINALSLD

Sequences:

>Translated_764_residues
MESIQLNITGMKCGGCVSTVEKILNNSDGIENVSVNLLTESAYFEITQNHIEIESVLENLKENGFPSKIYINDFSKKINK
SELEKKKKWNNQWKKLTFALLLLFFSGLGHLAEGRYINFPILGNILFHASLATLALLFPGRGIIINGFKSFIKNHPDMDS
LVALGVISAYTTSLLSLIFPATGFPCFFNEPVMLLGFILIGRFLEERARYQTGSSIGELLDLQPEMANIYTEDNHIKSIR
VNTLRPDQEIQVLAGDRVPADCIVTQGNSYVDVSHITGESKPIEVKEGEILSSGSLNLNSTLRLKVQKVGGDSSLAKLVN
LIESVNARKPRIQRVADEIAGKFTYFVLIFATLTFFFWWKGARNIWPDLLSHNNQLITHSSHTLHSSLGSNAENFLSLAI
QLSIAVLVIACPCALGLATPTVITVASGKAAKKGVLFKGGDKIEMASKINHIIFDKTGTLTKGKPFIVDYKNNDDHSFLL
RIAASLEKESRHPIADALIQEAKKQNLSLFPIKKIFNHTGRGISGELESIDGLINIGNIEWLVSKGIIIDSDAKKVIENE
ETKTNTIIGVSIKDKLLGFVFLGDLLRDDSIKTVQNLRENKFKINILSGDRKQTVLALAKKIGCKETEVKWDLLPEMKLK
TIENLKINNKVAMIGDGINDVPALASSDLGIAVGSGTQIAKANADVVLMGDQLNRLPYAFNLAKNTIRKIKQNLTWAFGY
NLLAIPLAAGILFPKYGILLTPSIAALLMAISSITVVINALSLD
>Mature_764_residues
MESIQLNITGMKCGGCVSTVEKILNNSDGIENVSVNLLTESAYFEITQNHIEIESVLENLKENGFPSKIYINDFSKKINK
SELEKKKKWNNQWKKLTFALLLLFFSGLGHLAEGRYINFPILGNILFHASLATLALLFPGRGIIINGFKSFIKNHPDMDS
LVALGVISAYTTSLLSLIFPATGFPCFFNEPVMLLGFILIGRFLEERARYQTGSSIGELLDLQPEMANIYTEDNHIKSIR
VNTLRPDQEIQVLAGDRVPADCIVTQGNSYVDVSHITGESKPIEVKEGEILSSGSLNLNSTLRLKVQKVGGDSSLAKLVN
LIESVNARKPRIQRVADEIAGKFTYFVLIFATLTFFFWWKGARNIWPDLLSHNNQLITHSSHTLHSSLGSNAENFLSLAI
QLSIAVLVIACPCALGLATPTVITVASGKAAKKGVLFKGGDKIEMASKINHIIFDKTGTLTKGKPFIVDYKNNDDHSFLL
RIAASLEKESRHPIADALIQEAKKQNLSLFPIKKIFNHTGRGISGELESIDGLINIGNIEWLVSKGIIIDSDAKKVIENE
ETKTNTIIGVSIKDKLLGFVFLGDLLRDDSIKTVQNLRENKFKINILSGDRKQTVLALAKKIGCKETEVKWDLLPEMKLK
TIENLKINNKVAMIGDGINDVPALASSDLGIAVGSGTQIAKANADVVLMGDQLNRLPYAFNLAKNTIRKIKQNLTWAFGY
NLLAIPLAAGILFPKYGILLTPSIAALLMAISSITVVINALSLD

Specific function: Involved in copper transport [H]

COG id: COG2217

COG function: function code P; Cation transport ATPase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HMA domain [H]

Homologues:

Organism=Homo sapiens, GI55743071, Length=820, Percent_Identity=31.4634146341463, Blast_Score=369, Evalue=1e-102,
Organism=Homo sapiens, GI115529486, Length=844, Percent_Identity=29.1469194312796, Blast_Score=349, Evalue=5e-96,
Organism=Homo sapiens, GI55743073, Length=578, Percent_Identity=28.8927335640138, Blast_Score=237, Evalue=4e-62,
Organism=Escherichia coli, GI1786691, Length=778, Percent_Identity=31.1053984575836, Blast_Score=342, Evalue=4e-95,
Organism=Escherichia coli, GI1789879, Length=716, Percent_Identity=28.072625698324, Blast_Score=233, Evalue=4e-62,
Organism=Escherichia coli, GI1786914, Length=493, Percent_Identity=25.7606490872211, Blast_Score=103, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17556548, Length=801, Percent_Identity=30.2122347066167, Blast_Score=300, Evalue=2e-81,
Organism=Saccharomyces cerevisiae, GI6320475, Length=696, Percent_Identity=33.4770114942529, Blast_Score=300, Evalue=5e-82,
Organism=Saccharomyces cerevisiae, GI6319772, Length=650, Percent_Identity=29.6923076923077, Blast_Score=270, Evalue=5e-73,
Organism=Saccharomyces cerevisiae, GI6325221, Length=580, Percent_Identity=22.7586206896552, Blast_Score=103, Evalue=7e-23,
Organism=Saccharomyces cerevisiae, GI6321430, Length=579, Percent_Identity=22.1070811744387, Blast_Score=102, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6321271, Length=188, Percent_Identity=28.7234042553192, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI221329854, Length=593, Percent_Identity=29.5109612141653, Blast_Score=209, Evalue=7e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008250
- InterPro:   IPR006403
- InterPro:   IPR006416
- InterPro:   IPR001757
- InterPro:   IPR018303
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR017969
- InterPro:   IPR006121
- InterPro:   IPR000150 [H]

Pfam domain/function: PF00122 E1-E2_ATPase; PF00403 HMA; PF00702 Hydrolase [H]

EC number: =3.6.3.4 [H]

Molecular weight: Translated: 83942; Mature: 83942

Theoretical pI: Translated: 9.02; Mature: 9.02

Prosite motif: PS00154 ATPASE_E1_E2 ; PS01047 HMA_1 ; PS50846 HMA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESIQLNITGMKCGGCVSTVEKILNNSDGIENVSVNLLTESAYFEITQNHIEIESVLENL
CCCEEEEEEEEECCHHHHHHHHHHCCCCCCCEEEEEEEECCCEEEECCCCEEHHHHHHHH
KENGFPSKIYINDFSKKINKSELEKKKKWNNQWKKLTFALLLLFFSGLGHLAEGRYINFP
HHCCCCCEEEEECHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCEECCH
ILGNILFHASLATLALLFPGRGIIINGFKSFIKNHPDMDSLVALGVISAYTTSLLSLIFP
HHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHC
ATGFPCFFNEPVMLLGFILIGRFLEERARYQTGSSIGELLDLQPEMANIYTEDNHIKSIR
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHCCCCCCEEEEE
VNTLRPDQEIQVLAGDRVPADCIVTQGNSYVDVSHITGESKPIEVKEGEILSSGSLNLNS
EECCCCCCCEEEEECCCCCCCEEEECCCCEEEEEEECCCCCCEEECCCCEEECCCCCCCC
TLRLKVQKVGGDSSLAKLVNLIESVNARKPRIQRVADEIAGKFTYFVLIFATLTFFFWWK
EEEEEEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GARNIWPDLLSHNNQLITHSSHTLHSSLGSNAENFLSLAIQLSIAVLVIACPCALGLATP
CCCCCCHHHHCCCCEEEECCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
TVITVASGKAAKKGVLFKGGDKIEMASKINHIIFDKTGTLTKGKPFIVDYKNNDDHSFLL
CEEEEECCCCCCCCCEEECCCCEEHHHHCCEEEECCCCCCCCCCCEEEEECCCCCHHHHH
RIAASLEKESRHPIADALIQEAKKQNLSLFPIKKIFNHTGRGISGELESIDGLINIGNIE
HHHHHHHHCCCCCHHHHHHHHHHHCCCCEEEHHHHHCCCCCCCCCCHHHCCCEEEECCEE
WLVSKGIIIDSDAKKVIENEETKTNTIIGVSIKDKLLGFVFLGDLLRDDSIKTVQNLREN
EEEECCEEEECCHHHHHCCCCCCCCEEEEEEHHHHHHHHHHHHHHHCCCCHHHHHHHHCC
KFKINILSGDRKQTVLALAKKIGCKETEVKWDLLPEMKLKTIENLKINNKVAMIGDGIND
CEEEEEECCCCHHHHHHHHHHHCCCCCCCEEECCCCHHHHHHHCEEECCEEEEEECCCCC
VPALASSDLGIAVGSGTQIAKANADVVLMGDQLNRLPYAFNLAKNTIRKIKQNLTWAFGY
CCHHCCCCCEEEECCCCEEEECCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCEEHHCC
NLLAIPLAAGILFPKYGILLTPSIAALLMAISSITVVINALSLD
HHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHHEECCCC
>Mature Secondary Structure
MESIQLNITGMKCGGCVSTVEKILNNSDGIENVSVNLLTESAYFEITQNHIEIESVLENL
CCCEEEEEEEEECCHHHHHHHHHHCCCCCCCEEEEEEEECCCEEEECCCCEEHHHHHHHH
KENGFPSKIYINDFSKKINKSELEKKKKWNNQWKKLTFALLLLFFSGLGHLAEGRYINFP
HHCCCCCEEEEECHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCEECCH
ILGNILFHASLATLALLFPGRGIIINGFKSFIKNHPDMDSLVALGVISAYTTSLLSLIFP
HHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHC
ATGFPCFFNEPVMLLGFILIGRFLEERARYQTGSSIGELLDLQPEMANIYTEDNHIKSIR
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHCCCCCCEEEEE
VNTLRPDQEIQVLAGDRVPADCIVTQGNSYVDVSHITGESKPIEVKEGEILSSGSLNLNS
EECCCCCCCEEEEECCCCCCCEEEECCCCEEEEEEECCCCCCEEECCCCEEECCCCCCCC
TLRLKVQKVGGDSSLAKLVNLIESVNARKPRIQRVADEIAGKFTYFVLIFATLTFFFWWK
EEEEEEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GARNIWPDLLSHNNQLITHSSHTLHSSLGSNAENFLSLAIQLSIAVLVIACPCALGLATP
CCCCCCHHHHCCCCEEEECCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
TVITVASGKAAKKGVLFKGGDKIEMASKINHIIFDKTGTLTKGKPFIVDYKNNDDHSFLL
CEEEEECCCCCCCCCEEECCCCEEHHHHCCEEEECCCCCCCCCCCEEEEECCCCCHHHHH
RIAASLEKESRHPIADALIQEAKKQNLSLFPIKKIFNHTGRGISGELESIDGLINIGNIE
HHHHHHHHCCCCCHHHHHHHHHHHCCCCEEEHHHHHCCCCCCCCCCHHHCCCEEEECCEE
WLVSKGIIIDSDAKKVIENEETKTNTIIGVSIKDKLLGFVFLGDLLRDDSIKTVQNLREN
EEEECCEEEECCHHHHHCCCCCCCCEEEEEEHHHHHHHHHHHHHHHCCCCHHHHHHHHCC
KFKINILSGDRKQTVLALAKKIGCKETEVKWDLLPEMKLKTIENLKINNKVAMIGDGIND
CEEEEEECCCCHHHHHHHHHHHCCCCCCCEEECCCCHHHHHHHCEEECCEEEEEECCCCC
VPALASSDLGIAVGSGTQIAKANADVVLMGDQLNRLPYAFNLAKNTIRKIKQNLTWAFGY
CCHHCCCCCEEEECCCCEEEECCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCEEHHCC
NLLAIPLAAGILFPKYGILLTPSIAALLMAISSITVVINALSLD
HHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHHEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7937823 [H]