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The map label for this gene is holB [H]

Identifier: 123967683

GI number: 123967683

Start: 135909

End: 136871

Strand: Reverse

Name: holB [H]

Synonym: A9601_01461

Alternate gene names: 123967683

Gene position: 136871-135909 (Counterclockwise)

Preceding gene: 123967684

Following gene: 123967681

Centisome position: 8.2

GC content: 25.44

Gene sequence:

>963_bases
ATGATTAAGGTTAAAAAAGATAATTTTTTCTTGAATGAAGAAGTCAATACCTGTCTTAACAACATAATTAAAAATAAATC
ATTTGCTAATGGTTATATATTTTATGGTGCTGAAGGACTAGGTAAAAAGCAAACTGCTCTTCAATTTATACAAGAGATTT
TCAAAAAGTCTTCACCAAGCAAAAATCTTGAAGAGAAAATTAAAAACAATAACCATCCTGATTTTTTAATTATTGAACCT
GATTCTCTTTTAGAAACAAAAAGTTCAGGTGGTTCCGATCTTGAAAAAAAAACAAAAAGTGGATCTGAGATTATTAAAAT
TGCTCAAATACGTAATATCAAAACTTTTCTTAGTCAAAAATCAATAAACTCAGAAAAAAAAATTGTTTTAATTATTGATG
CACACCTCTTAAACGAAGCAGCCTCAAATTGCCTTTTAAAAACTCTAGAAGAACCTAGTAACGGCATTTTTATTTTACTA
ACATCTAAATTAAACCTTCTCTTAGATACGATCATCTCAAGATGTCAAATCGTAAGATTTCGATCTTTTTCTAGTCAACA
AATAAAGTCTATTTTAAAAGAATATTTAGATACTTCTAAATCAAATATTAATGCAAAATTAGAATTTGAAGATTTAATAA
ACTCTGCAAATGGATCTCCAAATCAATTATTGAAAAATATTGAAATTTGGAATGATTTTTCAGATGAAATTATAATTAAA
TTGAATTCTCCAGTAAAAAATAGTCTCGAAATATTAGAAATATCTAAATTAATATCTGAAAAATTAGAAATTTTTCAACA
GATCAGTTTAGTAAATTTAATTCAAACTGTTTGGTGGAGAAAGACAAAAAATATAGGTTTAGTTAAAAAACTTGAAAAAT
TAAAATACCTCTTAAGAAAAAGCATCCAACCAAGGTTGGCATGGGAAATTACTTTTTTAAAAATTTCGATGGAAGATATA
TGA

Upstream 100 bases:

>100_bases
CCAAACAAAAAAACTGGAAAGTAATATCAGCTTCACAAAATATTCAAACTATTTCTAATCAAATTAAAGAGACTTTGCTA
AACAATTTTTCTAATAACAA

Downstream 100 bases:

>100_bases
TTTTAATCTACTGCAGAATTAATCAAATCAGGATTTCTGGTTTTAATAAACTCCTGCCTTGCAGTTTCAACTTGAGAACC
AATAGGTAACTCAAGACAAT

Product: DNA polymerase III subunit delta'

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MIKVKKDNFFLNEEVNTCLNNIIKNKSFANGYIFYGAEGLGKKQTALQFIQEIFKKSSPSKNLEEKIKNNNHPDFLIIEP
DSLLETKSSGGSDLEKKTKSGSEIIKIAQIRNIKTFLSQKSINSEKKIVLIIDAHLLNEAASNCLLKTLEEPSNGIFILL
TSKLNLLLDTIISRCQIVRFRSFSSQQIKSILKEYLDTSKSNINAKLEFEDLINSANGSPNQLLKNIEIWNDFSDEIIIK
LNSPVKNSLEILEISKLISEKLEIFQQISLVNLIQTVWWRKTKNIGLVKKLEKLKYLLRKSIQPRLAWEITFLKISMEDI

Sequences:

>Translated_320_residues
MIKVKKDNFFLNEEVNTCLNNIIKNKSFANGYIFYGAEGLGKKQTALQFIQEIFKKSSPSKNLEEKIKNNNHPDFLIIEP
DSLLETKSSGGSDLEKKTKSGSEIIKIAQIRNIKTFLSQKSINSEKKIVLIIDAHLLNEAASNCLLKTLEEPSNGIFILL
TSKLNLLLDTIISRCQIVRFRSFSSQQIKSILKEYLDTSKSNINAKLEFEDLINSANGSPNQLLKNIEIWNDFSDEIIIK
LNSPVKNSLEILEISKLISEKLEIFQQISLVNLIQTVWWRKTKNIGLVKKLEKLKYLLRKSIQPRLAWEITFLKISMEDI
>Mature_320_residues
MIKVKKDNFFLNEEVNTCLNNIIKNKSFANGYIFYGAEGLGKKQTALQFIQEIFKKSSPSKNLEEKIKNNNHPDFLIIEP
DSLLETKSSGGSDLEKKTKSGSEIIKIAQIRNIKTFLSQKSINSEKKIVLIIDAHLLNEAASNCLLKTLEEPSNGIFILL
TSKLNLLLDTIISRCQIVRFRSFSSQQIKSILKEYLDTSKSNINAKLEFEDLINSANGSPNQLLKNIEIWNDFSDEIIIK
LNSPVKNSLEILEISKLISEKLEIFQQISLVNLIQTVWWRKTKNIGLVKKLEKLKYLLRKSIQPRLAWEITFLKISMEDI

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria [H]

COG id: COG0470

COG function: function code L; ATPase involved in DNA replication

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004622 [H]

Pfam domain/function: NA

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 36633; Mature: 36633

Theoretical pI: Translated: 9.91; Mature: 9.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKVKKDNFFLNEEVNTCLNNIIKNKSFANGYIFYGAEGLGKKQTALQFIQEIFKKSSPS
CEEEECCCEEECHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCC
KNLEEKIKNNNHPDFLIIEPDSLLETKSSGGSDLEKKTKSGSEIIKIAQIRNIKTFLSQK
CCHHHHHCCCCCCCEEEECCHHHHHCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHH
SINSEKKIVLIIDAHLLNEAASNCLLKTLEEPSNGIFILLTSKLNLLLDTIISRCQIVRF
CCCCCCCEEEEEEHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHH
RSFSSQQIKSILKEYLDTSKSNINAKLEFEDLINSANGSPNQLLKNIEIWNDFSDEIIIK
HCCCHHHHHHHHHHHHCCCCCCCEEEEEHHHHHCCCCCCHHHHHHHHHHHCCCCCEEEEE
LNSPVKNSLEILEISKLISEKLEIFQQISLVNLIQTVWWRKTKNIGLVKKLEKLKYLLRK
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
SIQPRLAWEITFLKISMEDI
CCCCCEEEEEEEEEEEECCC
>Mature Secondary Structure
MIKVKKDNFFLNEEVNTCLNNIIKNKSFANGYIFYGAEGLGKKQTALQFIQEIFKKSSPS
CEEEECCCEEECHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCC
KNLEEKIKNNNHPDFLIIEPDSLLETKSSGGSDLEKKTKSGSEIIKIAQIRNIKTFLSQK
CCHHHHHCCCCCCCEEEECCHHHHHCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHH
SINSEKKIVLIIDAHLLNEAASNCLLKTLEEPSNGIFILLTSKLNLLLDTIISRCQIVRF
CCCCCCCEEEEEEHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHH
RSFSSQQIKSILKEYLDTSKSNINAKLEFEDLINSANGSPNQLLKNIEIWNDFSDEIIIK
HCCCHHHHHHHHHHHHCCCCCCCEEEEEHHHHHCCCCCCHHHHHHHHHHHCCCCCEEEEE
LNSPVKNSLEILEISKLISEKLEIFQQISLVNLIQTVWWRKTKNIGLVKKLEKLKYLLRK
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
SIQPRLAWEITFLKISMEDI
CCCCCEEEEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]