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The map label for this gene is clpX [H]

Identifier: 123967080

GI number: 123967080

Start: 1634493

End: 1635860

Strand: Direct

Name: clpX [H]

Synonym: P9515_18471

Alternate gene names: 123967080

Gene position: 1634493-1635860 (Clockwise)

Preceding gene: 123967079

Following gene: 123967081

Centisome position: 95.91

GC content: 33.26

Gene sequence:

>1368_bases
ATGGCTAAATTTGACGCCCATCTAAAATGTTCATTTTGTGCCAAATCACAAGATCAAGTTAGAAAACTTATAGCAGGTCC
TGGGGTATACATCTGTGATGAATGCATAGACCTATGTAATGAAATTCTCGATGAAGAATTAATTGATACTCAGGCAAAAC
TTAATAACTCCACACAAGTCAAGAAAAAATTACCGATTAATAATCCTGATACATCTATCCCTTTCGAATTAACCTCCATT
CCCAAACCACTGGAAATTAAAACTTTTCTAGATAACCAAGTTGTAGGTCAAGAATCTGCAAAAAAAATACTTTCAGTTGC
TGTTTATAATCACTATAAAAGGTTAACTTGGAGATTAAAAGAAGAAAATAAGGACAATAATTCTAACGATTGTCATGCAA
CTAAACTTCAAAAATCAAATATCCTACTGATTGGTCCAACTGGAAGTGGTAAAACATTATTAGCACAAACTTTAGCTGAG
TTTCTTGATGTTCCTTTTGCAGTGGCTGATGCAACGACTCTAACTGAAGCTGGATATGTTGGAGAGGATGTTGAGAATAT
TCTATTAAGACTTCTACAAAAGTCAGAAATGAATGTAGATTTAGCTCAAAAGGGTATTATATATATTGATGAGATAGACA
AGATAGCTAGAAAGAGTGAAAATCCATCAATTACAAGAGATGTATCTGGAGAAGGAGTTCAACAAGCATTATTAAAAATG
CTTGAGGGAACAATTGCAAATGTCCCTCCTCAAGGAGGACGAAAACACCCTTACCATGATTGTATACAGATAGATACAAG
TCAGATTTTATTTATATGTGGAGGTGCATTTATAGGTTTAGAAGATATTGTTCAAAAACGCTTAGGAAGACACTCTATAG
GATTTACAACCAACTCAGACGAAAGCAAAATAGATGCAAAAAAATTAGTTGATTCTCGAGATGCTCTCAAGAATTTAGAA
CTAGATGATTTAGTCAAATATGGATTAATTCCAGAATTTATAGGGAGAATTCCTGTATGCGCAGTATTAGATCGTCTCAC
TAAAGAAACTCTTGAATCGATCTTAACTGAACCAAGAGATGCACTAGTAAAGCAATTTAAAACTTTATTAAGTATGGATA
ATGTTGAATTAAATTTCGAACCCGAATCTGTGGAAGCAATCGCTAATGAAGCTTTTAAAAGAAAAACAGGTGCTAGAGCT
CTTAGATCAATAATTGAAGAATTAATGCTTGATTTAATGTATACACTCCCATCACAAGAAGAAGTAACTAAGTTCACCAT
TACGAAAAAAATGGTAGACAACCTGTTCTCATCTAAAATTGTTAAACTTCCTGCAGGTTCACATAGGATTATTAAAGAAT
CTGCATAA

Upstream 100 bases:

>100_bases
ACTAATATTTTAAGAATATGATGACGAATCCAAATTTATAAGCAATCCTAATAATAAGGGATAGTTACCCTTTTTTATTT
TTCACAAGCTTTGATAATCG

Downstream 100 bases:

>100_bases
AAGTAAGGTTAACTCTCTATGATTTCAAGATTATTCATATAATTAATAATCATAAATGCTTAATATACATAAACCTTTTC
ATCAAAAATATAGGCCTAGC

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 455; Mature: 454

Protein sequence:

>455_residues
MAKFDAHLKCSFCAKSQDQVRKLIAGPGVYICDECIDLCNEILDEELIDTQAKLNNSTQVKKKLPINNPDTSIPFELTSI
PKPLEIKTFLDNQVVGQESAKKILSVAVYNHYKRLTWRLKEENKDNNSNDCHATKLQKSNILLIGPTGSGKTLLAQTLAE
FLDVPFAVADATTLTEAGYVGEDVENILLRLLQKSEMNVDLAQKGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKM
LEGTIANVPPQGGRKHPYHDCIQIDTSQILFICGGAFIGLEDIVQKRLGRHSIGFTTNSDESKIDAKKLVDSRDALKNLE
LDDLVKYGLIPEFIGRIPVCAVLDRLTKETLESILTEPRDALVKQFKTLLSMDNVELNFEPESVEAIANEAFKRKTGARA
LRSIIEELMLDLMYTLPSQEEVTKFTITKKMVDNLFSSKIVKLPAGSHRIIKESA

Sequences:

>Translated_455_residues
MAKFDAHLKCSFCAKSQDQVRKLIAGPGVYICDECIDLCNEILDEELIDTQAKLNNSTQVKKKLPINNPDTSIPFELTSI
PKPLEIKTFLDNQVVGQESAKKILSVAVYNHYKRLTWRLKEENKDNNSNDCHATKLQKSNILLIGPTGSGKTLLAQTLAE
FLDVPFAVADATTLTEAGYVGEDVENILLRLLQKSEMNVDLAQKGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKM
LEGTIANVPPQGGRKHPYHDCIQIDTSQILFICGGAFIGLEDIVQKRLGRHSIGFTTNSDESKIDAKKLVDSRDALKNLE
LDDLVKYGLIPEFIGRIPVCAVLDRLTKETLESILTEPRDALVKQFKTLLSMDNVELNFEPESVEAIANEAFKRKTGARA
LRSIIEELMLDLMYTLPSQEEVTKFTITKKMVDNLFSSKIVKLPAGSHRIIKESA
>Mature_454_residues
AKFDAHLKCSFCAKSQDQVRKLIAGPGVYICDECIDLCNEILDEELIDTQAKLNNSTQVKKKLPINNPDTSIPFELTSIP
KPLEIKTFLDNQVVGQESAKKILSVAVYNHYKRLTWRLKEENKDNNSNDCHATKLQKSNILLIGPTGSGKTLLAQTLAEF
LDVPFAVADATTLTEAGYVGEDVENILLRLLQKSEMNVDLAQKGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKML
EGTIANVPPQGGRKHPYHDCIQIDTSQILFICGGAFIGLEDIVQKRLGRHSIGFTTNSDESKIDAKKLVDSRDALKNLEL
DDLVKYGLIPEFIGRIPVCAVLDRLTKETLESILTEPRDALVKQFKTLLSMDNVELNFEPESVEAIANEAFKRKTGARAL
RSIIEELMLDLMYTLPSQEEVTKFTITKKMVDNLFSSKIVKLPAGSHRIIKESA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=329, Percent_Identity=46.8085106382979, Blast_Score=286, Evalue=2e-77,
Organism=Escherichia coli, GI1786642, Length=430, Percent_Identity=56.046511627907, Blast_Score=471, Evalue=1e-134,
Organism=Escherichia coli, GI1790366, Length=217, Percent_Identity=30.8755760368664, Blast_Score=86, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI71982908, Length=297, Percent_Identity=45.7912457912458, Blast_Score=268, Evalue=6e-72,
Organism=Caenorhabditis elegans, GI71982905, Length=339, Percent_Identity=42.7728613569322, Blast_Score=267, Evalue=7e-72,
Organism=Caenorhabditis elegans, GI71988663, Length=396, Percent_Identity=39.6464646464646, Blast_Score=253, Evalue=2e-67,
Organism=Caenorhabditis elegans, GI71988660, Length=251, Percent_Identity=40.2390438247012, Blast_Score=166, Evalue=3e-41,
Organism=Saccharomyces cerevisiae, GI6319704, Length=431, Percent_Identity=37.3549883990719, Blast_Score=245, Evalue=1e-65,
Organism=Drosophila melanogaster, GI24648289, Length=315, Percent_Identity=46.3492063492063, Blast_Score=279, Evalue=2e-75,
Organism=Drosophila melanogaster, GI24648291, Length=315, Percent_Identity=46.3492063492063, Blast_Score=279, Evalue=2e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 50687; Mature: 50556

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKFDAHLKCSFCAKSQDQVRKLIAGPGVYICDECIDLCNEILDEELIDTQAKLNNSTQV
CCCCCCCEEEEHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
KKKLPINNPDTSIPFELTSIPKPLEIKTFLDNQVVGQESAKKILSVAVYNHYKRLTWRLK
HHCCCCCCCCCCCCEEECCCCCCCCHHHHHCCHHCCHHHHHHHHHHHHHHHHHHHHHHHH
EENKDNNSNDCHATKLQKSNILLIGPTGSGKTLLAQTLAEFLDVPFAVADATTLTEAGYV
HCCCCCCCCCCHHHEECCCCEEEEECCCCCHHHHHHHHHHHHCCCHHHHCHHHHHHCCCC
GEDVENILLRLLQKSEMNVDLAQKGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKM
CHHHHHHHHHHHHHHCCCCCHHHCCCEEEHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHH
LEGTIANVPPQGGRKHPYHDCIQIDTSQILFICGGAFIGLEDIVQKRLGRHSIGFTTNSD
HHHHHCCCCCCCCCCCCCHHHEEECCHHEEEEECCHHCCHHHHHHHHHCCCCCCCCCCCC
ESKIDAKKLVDSRDALKNLELDDLVKYGLIPEFIGRIPVCAVLDRLTKETLESILTEPRD
CHHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHCCHHH
ALVKQFKTLLSMDNVELNFEPESVEAIANEAFKRKTGARALRSIIEELMLDLMYTLPSQE
HHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
EVTKFTITKKMVDNLFSSKIVKLPAGSHRIIKESA
HHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCC
>Mature Secondary Structure 
AKFDAHLKCSFCAKSQDQVRKLIAGPGVYICDECIDLCNEILDEELIDTQAKLNNSTQV
CCCCCCEEEEHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
KKKLPINNPDTSIPFELTSIPKPLEIKTFLDNQVVGQESAKKILSVAVYNHYKRLTWRLK
HHCCCCCCCCCCCCEEECCCCCCCCHHHHHCCHHCCHHHHHHHHHHHHHHHHHHHHHHHH
EENKDNNSNDCHATKLQKSNILLIGPTGSGKTLLAQTLAEFLDVPFAVADATTLTEAGYV
HCCCCCCCCCCHHHEECCCCEEEEECCCCCHHHHHHHHHHHHCCCHHHHCHHHHHHCCCC
GEDVENILLRLLQKSEMNVDLAQKGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKM
CHHHHHHHHHHHHHHCCCCCHHHCCCEEEHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHH
LEGTIANVPPQGGRKHPYHDCIQIDTSQILFICGGAFIGLEDIVQKRLGRHSIGFTTNSD
HHHHHCCCCCCCCCCCCCHHHEEECCHHEEEEECCHHCCHHHHHHHHHCCCCCCCCCCCC
ESKIDAKKLVDSRDALKNLELDDLVKYGLIPEFIGRIPVCAVLDRLTKETLESILTEPRD
CHHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHCCHHH
ALVKQFKTLLSMDNVELNFEPESVEAIANEAFKRKTGARALRSIIEELMLDLMYTLPSQE
HHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
EVTKFTITKKMVDNLFSSKIVKLPAGSHRIIKESA
HHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA