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The map label for this gene is argC

Identifier: 123966207

GI number: 123966207

Start: 870517

End: 871572

Strand: Reverse

Name: argC

Synonym: P9515_09741

Alternate gene names: 123966207

Gene position: 871572-870517 (Counterclockwise)

Preceding gene: 123966209

Following gene: 123966205

Centisome position: 51.14

GC content: 30.21

Gene sequence:

>1056_bases
ATGAATGTTGCAATAGTTGGTGCTACTGGTTACGGGGGAATACAATCAGTAAATTTATTAAAGGATAATAAAAACTACAA
AATATCCTATTTAGGAGGGTATAAAACTTCAGGAACAAAATGGAGTGATAATTTTCCATTTATAAAATTAGACTCGAATA
ATTTAATTGAAAAAATATCCATAGACAGGATCGCTGATAAAGCAGATGTTGCTTTACTTTGCTTACCGAATGGAATTTCT
TCTACTTTAACAAGAGGTTTATTAGAAAAAGGTGTAAAAGTAATTGATTTATCAGCCGATTATAGATACAAGTCTCTTGA
ACAATGGAAAAGAATTTACTCTAATGAAGCGGCAAAATATAAAAGAGATGATGATGATTTGTGTAAGGAAGCAGTTTATG
GTCTCCCTGAAATTAATAATAAAGATATTTCTAAAGCAAGGTTAATAGCATGTCCTGGTTGTTATCCAACTTCTGCTCTA
ATTCCTCTAATCCCCTTTTTATCTCAAGGAATTATTGATAATGAGGGCATAATAATAGATTCTAAAAGTGGTACATCAGG
TGGTGGAAGAGAATCTAGTCAAAAATTATTATTTTCGGAATGTGGAGATGGCCTTTCTGCATATGGATTAATTAATCATA
GACATACTTCTGAAATAGAGCAAATCGCGAGTTTTATTTCAGGTAACGATATTGAACTATTATTCACTCCGCATTTATTA
CCAATGATAAGAGGTATGCATTCGACAATATATGGAAGATTAAGAGATCCAGGCTTAACTTCTTCTGATTGTAGAATTAT
ATTAGAAAATTTCTATAGAAACTATTCTAATATTAGAGTTTTACCTGTTGATATTTACCCTTCCACCAAATGGGTCAAAA
ATACAAACGAAATTCACTTATCCGTTAAAGTTGATAATAGAAATGGAAGAATTATTTTATTATCAGTAATAGATAATTTA
CTTAAAGGACAAACAGGTCAAGCTATACAAAATCTTAATCTTATATCTGGTTTACCATTAAATAATGGATTAGAAATGAT
TAATCATTACCCTTGA

Upstream 100 bases:

>100_bases
TGTTTCTTTCATTATTACTATTCAAGATAGAAAAAAGTGTTTTAATTATTGTTTATTTCAACACTATTAATCCTAACTTA
AAGTTTGCCAATAAAGAGAT

Downstream 100 bases:

>100_bases
AGCTATTTCTTACTATAAATCCTGCCTGCGAAATTGAGAGTGGTAAAATCTTATGTTCCAAAAAATGTATTTTCTTCGAT
ATGGTCTCTAAGTTGTCTTG

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MNVAIVGATGYGGIQSVNLLKDNKNYKISYLGGYKTSGTKWSDNFPFIKLDSNNLIEKISIDRIADKADVALLCLPNGIS
STLTRGLLEKGVKVIDLSADYRYKSLEQWKRIYSNEAAKYKRDDDDLCKEAVYGLPEINNKDISKARLIACPGCYPTSAL
IPLIPFLSQGIIDNEGIIIDSKSGTSGGGRESSQKLLFSECGDGLSAYGLINHRHTSEIEQIASFISGNDIELLFTPHLL
PMIRGMHSTIYGRLRDPGLTSSDCRIILENFYRNYSNIRVLPVDIYPSTKWVKNTNEIHLSVKVDNRNGRIILLSVIDNL
LKGQTGQAIQNLNLISGLPLNNGLEMINHYP

Sequences:

>Translated_351_residues
MNVAIVGATGYGGIQSVNLLKDNKNYKISYLGGYKTSGTKWSDNFPFIKLDSNNLIEKISIDRIADKADVALLCLPNGIS
STLTRGLLEKGVKVIDLSADYRYKSLEQWKRIYSNEAAKYKRDDDDLCKEAVYGLPEINNKDISKARLIACPGCYPTSAL
IPLIPFLSQGIIDNEGIIIDSKSGTSGGGRESSQKLLFSECGDGLSAYGLINHRHTSEIEQIASFISGNDIELLFTPHLL
PMIRGMHSTIYGRLRDPGLTSSDCRIILENFYRNYSNIRVLPVDIYPSTKWVKNTNEIHLSVKVDNRNGRIILLSVIDNL
LKGQTGQAIQNLNLISGLPLNNGLEMINHYP
>Mature_351_residues
MNVAIVGATGYGGIQSVNLLKDNKNYKISYLGGYKTSGTKWSDNFPFIKLDSNNLIEKISIDRIADKADVALLCLPNGIS
STLTRGLLEKGVKVIDLSADYRYKSLEQWKRIYSNEAAKYKRDDDDLCKEAVYGLPEINNKDISKARLIACPGCYPTSAL
IPLIPFLSQGIIDNEGIIIDSKSGTSGGGRESSQKLLFSECGDGLSAYGLINHRHTSEIEQIASFISGNDIELLFTPHLL
PMIRGMHSTIYGRLRDPGLTSSDCRIILENFYRNYSNIRVLPVDIYPSTKWVKNTNEIHLSVKVDNRNGRIILLSVIDNL
LKGQTGQAIQNLNLISGLPLNNGLEMINHYP

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790396, Length=342, Percent_Identity=30.9941520467836, Blast_Score=131, Evalue=8e-32,
Organism=Saccharomyces cerevisiae, GI6320913, Length=341, Percent_Identity=25.8064516129032, Blast_Score=99, Evalue=9e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGC_PROM5 (A2BWM0)

Other databases:

- EMBL:   CP000552
- RefSeq:   YP_001011288.1
- ProteinModelPortal:   A2BWM0
- SMR:   A2BWM0
- STRING:   A2BWM0
- GeneID:   4719207
- GenomeReviews:   CP000552_GR
- KEGG:   pmc:P9515_09741
- eggNOG:   COG0002
- HOGENOM:   HBG294213
- OMA:   VCRIAVH
- ProtClustDB:   PRK00436
- BioCyc:   PMAR167542:P9515ORF_1020-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00150
- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280
- Gene3D:   G3DSA:3.40.50.720
- SMART:   SM00859
- TIGRFAMs:   TIGR01850

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC

EC number: =1.2.1.38

Molecular weight: Translated: 38887; Mature: 38887

Theoretical pI: Translated: 8.10; Mature: 8.10

Prosite motif: PS01224 ARGC

Important sites: ACT_SITE 154-154

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVAIVGATGYGGIQSVNLLKDNKNYKISYLGGYKTSGTKWSDNFPFIKLDSNNLIEKIS
CCEEEEEECCCCCCEEEEEEECCCCEEEEEECCCCCCCCEECCCCCEEEECCCCCHHHHH
IDRIADKADVALLCLPNGISSTLTRGLLEKGVKVIDLSADYRYKSLEQWKRIYSNEAAKY
HHHHCCCCCEEEEEECCCHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHCCCCHHC
KRDDDDLCKEAVYGLPEINNKDISKARLIACPGCYPTSALIPLIPFLSQGIIDNEGIIID
CCCHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCEEEE
SKSGTSGGGRESSQKLLFSECGDGLSAYGLINHRHTSEIEQIASFISGNDIELLFTPHLL
CCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHCCCCEEEEECCHHH
PMIRGMHSTIYGRLRDPGLTSSDCRIILENFYRNYSNIRVLPVDIYPSTKWVKNTNEIHL
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEEECCCCCEECCCCEEEE
SVKVDNRNGRIILLSVIDNLLKGQTGQAIQNLNLISGLPLNNGLEMINHYP
EEEEECCCCCEEEHHHHHHHHCCCCCHHHHCCHHHCCCCCCCCHHHHCCCC
>Mature Secondary Structure
MNVAIVGATGYGGIQSVNLLKDNKNYKISYLGGYKTSGTKWSDNFPFIKLDSNNLIEKIS
CCEEEEEECCCCCCEEEEEEECCCCEEEEEECCCCCCCCEECCCCCEEEECCCCCHHHHH
IDRIADKADVALLCLPNGISSTLTRGLLEKGVKVIDLSADYRYKSLEQWKRIYSNEAAKY
HHHHCCCCCEEEEEECCCHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHCCCCHHC
KRDDDDLCKEAVYGLPEINNKDISKARLIACPGCYPTSALIPLIPFLSQGIIDNEGIIID
CCCHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCEEEE
SKSGTSGGGRESSQKLLFSECGDGLSAYGLINHRHTSEIEQIASFISGNDIELLFTPHLL
CCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHCCCCEEEEECCHHH
PMIRGMHSTIYGRLRDPGLTSSDCRIILENFYRNYSNIRVLPVDIYPSTKWVKNTNEIHL
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEEECCCCCEECCCCEEEE
SVKVDNRNGRIILLSVIDNLLKGQTGQAIQNLNLISGLPLNNGLEMINHYP
EEEEECCCCCEEEHHHHHHHHCCCCCHHHHCCHHHCCCCCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA