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The map label for this gene is nadA [H]

Identifier: 123965986

GI number: 123965986

Start: 680540

End: 681454

Strand: Reverse

Name: nadA [H]

Synonym: P9515_07511

Alternate gene names: 123965986

Gene position: 681454-680540 (Counterclockwise)

Preceding gene: 123965988

Following gene: 123965982

Centisome position: 39.99

GC content: 31.58

Gene sequence:

>915_bases
TTGATTTCTGAAATCAAGGAGCGTTGCTTAGAAACCAATGCGATAATTCTTGCTCATTATTATCAAGCGCCAGAGATACA
AGATATTGCTGATTTTATTGGGGATTCTTTAGATCTATCTAGGAAAGCAGCAAATAATAATGCAGATATAATAATTTTTT
GTGGTGTCCACTTTATGGCAGAAACAGCGAAAATACTTAGCCCAAATAAAACAGTATTATTACCTGATATTGATGCAGGT
TGTTCTTTGGCAGATGATTGTCCTGCAGAAGAATTCCAAAAGTTTAGAGATGAGAATCCAGATCATTATGTTGTGAGTTA
CATAAACTGTACTGCAGAAGTAAAAGCTCAAAGTGATTTGATATGTACTAGTAGCAATGCTGTTTCATTAGTAGAAAAGA
TACCTAAAGATAAAAAGATCATATTTGCACCAGATCAGAATCTAGGTAGATGGGTTCAAAAAAATTCTGGTAGAAACCTT
AAACTTTGGCCAGGTAGCTGTATAGTTCATGAAACATTTAGCGAAGAAGCTTTATTAAAATTAAGATATAAATATCCAGA
AGCGAAGGTAATAGCTCATCCTGAATGTAGTCAAAATTTGTTAGTACTTTCAGATTTTATTGGTTCGACAAGTAAGTTAC
TTGAATTTATTAGAGATGATCATTCTAATACTTATATGGTTTTAACTGAACCGGGGATAATTCATCAAATGAAAAAGAAA
GAACCTAATAAGAAATTTATTGAAGTGCCAGATATAGATGGGTGTAAATGTAATGAATGTCCCTATATGAAATTAAATAC
ACTAGATAAAATTTTAGATTGTTTGAAAAATAATTCTCCATCAATTGAATTGGAACCTGAAATAATTAAAAAAGCTTATA
AGCCCATAAAGAGGATGCTAGATATGAGCAGCTAA

Upstream 100 bases:

>100_bases
TTTTTCTATTTAAAGGCATATAATCTATTAAGAGACATTGTAAATCCTGACCAGTATAACTTCTACTGCAAAACAGAAAT
CTATTAAAAACGAAAAAGAT

Downstream 100 bases:

>100_bases
TAAAATTTATAAACCAGATTATGGTATTTCTCTCCAAAAACTTCTGATAAATTTGAAGAATTTGGTTCAAAATTTCTTAC
TAAATCAGATTTTTTAATCA

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MISEIKERCLETNAIILAHYYQAPEIQDIADFIGDSLDLSRKAANNNADIIIFCGVHFMAETAKILSPNKTVLLPDIDAG
CSLADDCPAEEFQKFRDENPDHYVVSYINCTAEVKAQSDLICTSSNAVSLVEKIPKDKKIIFAPDQNLGRWVQKNSGRNL
KLWPGSCIVHETFSEEALLKLRYKYPEAKVIAHPECSQNLLVLSDFIGSTSKLLEFIRDDHSNTYMVLTEPGIIHQMKKK
EPNKKFIEVPDIDGCKCNECPYMKLNTLDKILDCLKNNSPSIELEPEIIKKAYKPIKRMLDMSS

Sequences:

>Translated_304_residues
MISEIKERCLETNAIILAHYYQAPEIQDIADFIGDSLDLSRKAANNNADIIIFCGVHFMAETAKILSPNKTVLLPDIDAG
CSLADDCPAEEFQKFRDENPDHYVVSYINCTAEVKAQSDLICTSSNAVSLVEKIPKDKKIIFAPDQNLGRWVQKNSGRNL
KLWPGSCIVHETFSEEALLKLRYKYPEAKVIAHPECSQNLLVLSDFIGSTSKLLEFIRDDHSNTYMVLTEPGIIHQMKKK
EPNKKFIEVPDIDGCKCNECPYMKLNTLDKILDCLKNNSPSIELEPEIIKKAYKPIKRMLDMSS
>Mature_304_residues
MISEIKERCLETNAIILAHYYQAPEIQDIADFIGDSLDLSRKAANNNADIIIFCGVHFMAETAKILSPNKTVLLPDIDAG
CSLADDCPAEEFQKFRDENPDHYVVSYINCTAEVKAQSDLICTSSNAVSLVEKIPKDKKIIFAPDQNLGRWVQKNSGRNL
KLWPGSCIVHETFSEEALLKLRYKYPEAKVIAHPECSQNLLVLSDFIGSTSKLLEFIRDDHSNTYMVLTEPGIIHQMKKK
EPNKKFIEVPDIDGCKCNECPYMKLNTLDKILDCLKNNSPSIELEPEIIKKAYKPIKRMLDMSS

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 2 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=312, Percent_Identity=40.0641025641026, Blast_Score=247, Evalue=8e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473
- InterPro:   IPR023066 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 34359; Mature: 34359

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
3.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISEIKERCLETNAIILAHYYQAPEIQDIADFIGDSLDLSRKAANNNADIIIFCGVHFMA
CCHHHHHHHHCCCEEEEEEECCCCCHHHHHHHCCCCHHHHHHCCCCCCCEEEEECHHHHH
ETAKILSPNKTVLLPDIDAGCSLADDCPAEEFQKFRDENPDHYVVSYINCTAEVKAQSDL
HHHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHCCCCCEEEEEEEECEEEECCCCCE
ICTSSNAVSLVEKIPKDKKIIFAPDQNLGRWVQKNSGRNLKLWPGSCIVHETFSEEALLK
EEECCCHHHHHHHCCCCCEEEECCCCCHHHHHHCCCCCEEEECCCCEEEECCCCHHHEEE
LRYKYPEAKVIAHPECSQNLLVLSDFIGSTSKLLEFIRDDHSNTYMVLTEPGIIHQMKKK
EEECCCCCEEEECCCCCCCEEEEHHHHCCHHHHHHHHHCCCCCEEEEEECCCHHHHHHHC
EPNKKFIEVPDIDGCKCNECPYMKLNTLDKILDCLKNNSPSIELEPEIIKKAYKPIKRML
CCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEECHHHHHHHHHHHHHHH
DMSS
CCCC
>Mature Secondary Structure
MISEIKERCLETNAIILAHYYQAPEIQDIADFIGDSLDLSRKAANNNADIIIFCGVHFMA
CCHHHHHHHHCCCEEEEEEECCCCCHHHHHHHCCCCHHHHHHCCCCCCCEEEEECHHHHH
ETAKILSPNKTVLLPDIDAGCSLADDCPAEEFQKFRDENPDHYVVSYINCTAEVKAQSDL
HHHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHCCCCCEEEEEEEECEEEECCCCCE
ICTSSNAVSLVEKIPKDKKIIFAPDQNLGRWVQKNSGRNLKLWPGSCIVHETFSEEALLK
EEECCCHHHHHHHCCCCCEEEECCCCCHHHHHHCCCCCEEEECCCCEEEECCCCHHHEEE
LRYKYPEAKVIAHPECSQNLLVLSDFIGSTSKLLEFIRDDHSNTYMVLTEPGIIHQMKKK
EEECCCCCEEEECCCCCCCEEEEHHHHCCHHHHHHHHHCCCCCEEEEEECCCHHHHHHHC
EPNKKFIEVPDIDGCKCNECPYMKLNTLDKILDCLKNNSPSIELEPEIIKKAYKPIKRML
CCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEECHHHHHHHHHHHHHHH
DMSS
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA