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The map label for this gene is aspC [H]

Identifier: 123965982

GI number: 123965982

Start: 675975

End: 677156

Strand: Reverse

Name: aspC [H]

Synonym: P9515_07471

Alternate gene names: 123965982

Gene position: 677156-675975 (Counterclockwise)

Preceding gene: 123965986

Following gene: 123965981

Centisome position: 39.74

GC content: 31.39

Gene sequence:

>1182_bases
ATGAGTGAAGTAAATTTATCAAAAAGAGCTCTCTCACTTGAACCTTCACTTACTCTCCAGATAAGTGCTAAAGCTAAAAA
ACTTTCAGAAGAGGGGAAAGATATCTGTAATTTAAGTGCTGGAGAACCAGATTTTGATGCTCCAAAAGAAATCTTAAATG
CCACAAGTCAGGCTATATTCGATGGACATACAAAATATGGTCCTGCCGCAGGGGATAAAGAACTTAGAAAAGCTATTGCA
AAAAAATTGCAGATTCAAAACAATTTAAATGTTGAATTTGAAAATGTAATGGTAACAAATGGAGCAAAGCAGGCAATTTA
TAATCTTTTCCAGGTTTTATTGAATGATGGTGACGAAGTGATAATACCTGCTCCATATTGGCTAAGCTATCCACAAATGG
TTAGATTGGCGGGTGGAAAACCTATCTTCCTAAATTCAGCCCCTGAAGATGGATTCAAAATTAATATACAAGATTTAAGA
TCTAAAATTTCCTCAAAAACTAAATTTATTATAATTAATTCTCCCAATAACCCAACTGGCAGAATAATGGCAAAAGAAGA
GTTATTACAAATTGCGGAAGTAGTAAGAGAGCATAAAAATATTAATGTTCTTTCAGATGAGATTTACGAATTAATTCTTA
AAAAAGAATTTCGTCATTTAAGTTTAGCTTCATTAGCTACTGATTTAAAAGAAAGAATTTTTATTATTAATGGTTTTGCA
AAAGGGTGGGCGATGACTGGCTGGAGAGTAGGTTATTTAGTAGGAAAAAAAGAGGTTATTAAAGCTTCATCCGCTTTACA
AAGTCAAAGCACAAGTAATGTTTGTTCTTTCGTTCAAAGAGGAGCTTTAGAAGCTTTAAAGATAAATCAAGAATTTTTCT
TAAAAATCAATAGTCATTATGATCTCAGAAGAGAAATACTTTATGAAGGCCTTAGAAATATTGAAGGTTTAGTTGTTCAT
CAACCTAATGGAGCTTTTTACGCATTTCCTAGATTACCTAATAAATCTATAAGTTCTGTTGATTTTTGCAAAAAAATCTT
AAATGATTATGGATTAGTAATAGTACCCGGGAAACCATTTGGAGATAATCAAAGCTTTAGAATATCTTGTGCAACATCAA
AAGAAAAAATTATTGACGGATTATCAAGGTTAAAAAAAGCGGTTCATAATTATTATTTTTAG

Upstream 100 bases:

>100_bases
AAGAAAATGAAGCAAATTAAACCAATCTGTGATACTTTTAATTATTCTTATTTTATGATTAAAAATCTTTAATAGTGATA
TCTAAAGAACTATAGATCAA

Downstream 100 bases:

>100_bases
AAAAATGTCATTACAATTCTTAAAAAAAACACTTTTAGCTTCTACATTACTTTTTACTATTTTTTCTTCACCCTTAAATG
CTTATAAAAAAGTTTTAAGA

Product: aminotransferases class-I

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 393; Mature: 392

Protein sequence:

>393_residues
MSEVNLSKRALSLEPSLTLQISAKAKKLSEEGKDICNLSAGEPDFDAPKEILNATSQAIFDGHTKYGPAAGDKELRKAIA
KKLQIQNNLNVEFENVMVTNGAKQAIYNLFQVLLNDGDEVIIPAPYWLSYPQMVRLAGGKPIFLNSAPEDGFKINIQDLR
SKISSKTKFIIINSPNNPTGRIMAKEELLQIAEVVREHKNINVLSDEIYELILKKEFRHLSLASLATDLKERIFIINGFA
KGWAMTGWRVGYLVGKKEVIKASSALQSQSTSNVCSFVQRGALEALKINQEFFLKINSHYDLRREILYEGLRNIEGLVVH
QPNGAFYAFPRLPNKSISSVDFCKKILNDYGLVIVPGKPFGDNQSFRISCATSKEKIIDGLSRLKKAVHNYYF

Sequences:

>Translated_393_residues
MSEVNLSKRALSLEPSLTLQISAKAKKLSEEGKDICNLSAGEPDFDAPKEILNATSQAIFDGHTKYGPAAGDKELRKAIA
KKLQIQNNLNVEFENVMVTNGAKQAIYNLFQVLLNDGDEVIIPAPYWLSYPQMVRLAGGKPIFLNSAPEDGFKINIQDLR
SKISSKTKFIIINSPNNPTGRIMAKEELLQIAEVVREHKNINVLSDEIYELILKKEFRHLSLASLATDLKERIFIINGFA
KGWAMTGWRVGYLVGKKEVIKASSALQSQSTSNVCSFVQRGALEALKINQEFFLKINSHYDLRREILYEGLRNIEGLVVH
QPNGAFYAFPRLPNKSISSVDFCKKILNDYGLVIVPGKPFGDNQSFRISCATSKEKIIDGLSRLKKAVHNYYF
>Mature_392_residues
SEVNLSKRALSLEPSLTLQISAKAKKLSEEGKDICNLSAGEPDFDAPKEILNATSQAIFDGHTKYGPAAGDKELRKAIAK
KLQIQNNLNVEFENVMVTNGAKQAIYNLFQVLLNDGDEVIIPAPYWLSYPQMVRLAGGKPIFLNSAPEDGFKINIQDLRS
KISSKTKFIIINSPNNPTGRIMAKEELLQIAEVVREHKNINVLSDEIYELILKKEFRHLSLASLATDLKERIFIINGFAK
GWAMTGWRVGYLVGKKEVIKASSALQSQSTSNVCSFVQRGALEALKINQEFFLKINSHYDLRREILYEGLRNIEGLVVHQ
PNGAFYAFPRLPNKSISSVDFCKKILNDYGLVIVPGKPFGDNQSFRISCATSKEKIIDGLSRLKKAVHNYYF

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=362, Percent_Identity=27.3480662983425, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI169881279, Length=362, Percent_Identity=27.3480662983425, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI56713254, Length=314, Percent_Identity=29.9363057324841, Blast_Score=142, Evalue=6e-34,
Organism=Homo sapiens, GI56713256, Length=314, Percent_Identity=29.9363057324841, Blast_Score=141, Evalue=9e-34,
Organism=Homo sapiens, GI4507369, Length=381, Percent_Identity=25.9842519685039, Blast_Score=128, Evalue=7e-30,
Organism=Homo sapiens, GI169881281, Length=266, Percent_Identity=25.9398496240602, Blast_Score=111, Evalue=1e-24,
Organism=Escherichia coli, GI1788627, Length=388, Percent_Identity=31.4432989690722, Blast_Score=165, Evalue=5e-42,
Organism=Escherichia coli, GI1786816, Length=379, Percent_Identity=26.9129287598945, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1788722, Length=405, Percent_Identity=26.1728395061728, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI48994949, Length=365, Percent_Identity=22.7397260273973, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1790797, Length=379, Percent_Identity=22.9551451187335, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1787710, Length=316, Percent_Identity=23.1012658227848, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17567663, Length=372, Percent_Identity=27.1505376344086, Blast_Score=133, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI71994472, Length=278, Percent_Identity=31.6546762589928, Blast_Score=132, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI71994476, Length=278, Percent_Identity=31.6546762589928, Blast_Score=132, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI17567369, Length=261, Percent_Identity=32.9501915708812, Blast_Score=122, Evalue=4e-28,
Organism=Saccharomyces cerevisiae, GI6322401, Length=357, Percent_Identity=27.4509803921569, Blast_Score=125, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6320317, Length=311, Percent_Identity=25.4019292604502, Blast_Score=90, Evalue=7e-19,
Organism=Saccharomyces cerevisiae, GI6323118, Length=339, Percent_Identity=23.3038348082596, Blast_Score=87, Evalue=6e-18,
Organism=Drosophila melanogaster, GI28573069, Length=347, Percent_Identity=25.3602305475504, Blast_Score=118, Evalue=7e-27,
Organism=Drosophila melanogaster, GI24646114, Length=347, Percent_Identity=25.3602305475504, Blast_Score=118, Evalue=7e-27,
Organism=Drosophila melanogaster, GI28573067, Length=347, Percent_Identity=25.3602305475504, Blast_Score=118, Evalue=7e-27,
Organism=Drosophila melanogaster, GI28573065, Length=347, Percent_Identity=25.3602305475504, Blast_Score=118, Evalue=7e-27,
Organism=Drosophila melanogaster, GI18859735, Length=382, Percent_Identity=22.5130890052356, Blast_Score=102, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43985; Mature: 43854

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEVNLSKRALSLEPSLTLQISAKAKKLSEEGKDICNLSAGEPDFDAPKEILNATSQAIF
CCCCCCCHHEEECCCCEEEEEEHHHHHHHHCCCHHCCCCCCCCCCCCHHHHHHHHHHHHH
DGHTKYGPAAGDKELRKAIAKKLQIQNNLNVEFENVMVTNGAKQAIYNLFQVLLNDGDEV
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEEECCHHHHHHHHHHHHHCCCCCE
IIPAPYWLSYPQMVRLAGGKPIFLNSAPEDGFKINIQDLRSKISSKTKFIIINSPNNPTG
EECCCHHHCCHHHHHHCCCCEEEECCCCCCCCEEEHHHHHHHHCCCEEEEEEECCCCCCC
RIMAKEELLQIAEVVREHKNINVLSDEIYELILKKEFRHLSLASLATDLKERIFIINGFA
CEEEHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCC
KGWAMTGWRVGYLVGKKEVIKASSALQSQSTSNVCSFVQRGALEALKINQEFFLKINSHY
CCCCCCCEEEEEEECHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHEEECCEEEEEECCCC
DLRREILYEGLRNIEGLVVHQPNGAFYAFPRLPNKSISSVDFCKKILNDYGLVIVPGKPF
HHHHHHHHHHHCCCCEEEEECCCCCEEEECCCCCCCCCHHHHHHHHHHCCCEEEECCCCC
GDNQSFRISCATSKEKIIDGLSRLKKAVHNYYF
CCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SEVNLSKRALSLEPSLTLQISAKAKKLSEEGKDICNLSAGEPDFDAPKEILNATSQAIF
CCCCCCHHEEECCCCEEEEEEHHHHHHHHCCCHHCCCCCCCCCCCCHHHHHHHHHHHHH
DGHTKYGPAAGDKELRKAIAKKLQIQNNLNVEFENVMVTNGAKQAIYNLFQVLLNDGDEV
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEEECCHHHHHHHHHHHHHCCCCCE
IIPAPYWLSYPQMVRLAGGKPIFLNSAPEDGFKINIQDLRSKISSKTKFIIINSPNNPTG
EECCCHHHCCHHHHHHCCCCEEEECCCCCCCCEEEHHHHHHHHCCCEEEEEEECCCCCCC
RIMAKEELLQIAEVVREHKNINVLSDEIYELILKKEFRHLSLASLATDLKERIFIINGFA
CEEEHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCC
KGWAMTGWRVGYLVGKKEVIKASSALQSQSTSNVCSFVQRGALEALKINQEFFLKINSHY
CCCCCCCEEEEEEECHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHEEECCEEEEEECCCC
DLRREILYEGLRNIEGLVVHQPNGAFYAFPRLPNKSISSVDFCKKILNDYGLVIVPGKPF
HHHHHHHHHHHCCCCEEEEECCCCCEEEECCCCCCCCCHHHHHHHHHHCCCEEEECCCCC
GDNQSFRISCATSKEKIIDGLSRLKKAVHNYYF
CCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]