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The map label for this gene is wbdQ [H]

Identifier: 123965960

GI number: 123965960

Start: 656181

End: 656666

Strand: Direct

Name: wbdQ [H]

Synonym: P9515_07251

Alternate gene names: 123965960

Gene position: 656181-656666 (Clockwise)

Preceding gene: 123965959

Following gene: 123965964

Centisome position: 38.5

GC content: 26.34

Gene sequence:

>486_bases
TTGATACTAAAAATGTTTTTAAACGAAAAATCATTTAAACAGGTAGCTAAGAATAGTCCAATTGCGGCTATTGATTTATG
TATATTTAATGAAGCTAAAGAAATCCTTTTAGGTAAGAGAATTAACCCTCCAGCAAAGAGTTTTTTCTTTGTTCCTGGTG
GCAGAATTAGGAAAGGTGAAACATTATTTATTTCAACAAAAAGGATCCTAAATAATGAAATGAATTATGAAATTACTGAA
AAAGATTTCAATACTTTTTCTTTATTAGGTGTATTTCAACATTTCTATAATGACAATTTTTGTGGGAATAAACAATTTTC
TAGTCACTATGTTGTAATCGTTTATTTGGTCCCATTGAAAATCTTAAAAAAGTCGAAATTTGGAAATTTTAAAGATCAAC
ATGATGAGTATATTTGGTACAACAAAACTACTCATGAGAATTTGTTAATACATCCTTACTGTAAAGAGTATTTTAAAAAA
TTATAA

Upstream 100 bases:

>100_bases
TTTCTTTAAAAACGTTAATCGCTTAAATCAAATATTAGAAAAAGAATCGTCGAGCTTATCTTTAAAAATTTAAAAACTTT
TTTAAATAATTTCTCTATGT

Downstream 100 bases:

>100_bases
ATTTAAGGTTATTCAAAGTTATTAATTTTTTCAATTATTTTTTTAACTTGATAACCACTCTTAAATGAGGGCAAGTCTCT
CTTTGATGCACCATTTACAG

Product: hypothetical protein

Products: GDP; mannose [C]

Alternate protein names: GDPMH [H]

Number of amino acids: Translated: 161; Mature: 161

Protein sequence:

>161_residues
MILKMFLNEKSFKQVAKNSPIAAIDLCIFNEAKEILLGKRINPPAKSFFFVPGGRIRKGETLFISTKRILNNEMNYEITE
KDFNTFSLLGVFQHFYNDNFCGNKQFSSHYVVIVYLVPLKILKKSKFGNFKDQHDEYIWYNKTTHENLLIHPYCKEYFKK
L

Sequences:

>Translated_161_residues
MILKMFLNEKSFKQVAKNSPIAAIDLCIFNEAKEILLGKRINPPAKSFFFVPGGRIRKGETLFISTKRILNNEMNYEITE
KDFNTFSLLGVFQHFYNDNFCGNKQFSSHYVVIVYLVPLKILKKSKFGNFKDQHDEYIWYNKTTHENLLIHPYCKEYFKK
L
>Mature_161_residues
MILKMFLNEKSFKQVAKNSPIAAIDLCIFNEAKEILLGKRINPPAKSFFFVPGGRIRKGETLFISTKRILNNEMNYEITE
KDFNTFSLLGVFQHFYNDNFCGNKQFSSHYVVIVYLVPLKILKKSKFGNFKDQHDEYIWYNKTTHENLLIHPYCKEYFKK
L

Specific function: It could participate in the regulation of cell wall biosynthesis by influencing the concentration of GDP-mannose or GDP-glucose in the cell. May be involved in the degradation of GDP-mannose and GDP-glucose, diverting the GDP to the synthesis of GDP-fucos

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI87082031, Length=160, Percent_Identity=36.25, Blast_Score=101, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR021161
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: NA

Molecular weight: Translated: 19034; Mature: 19034

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILKMFLNEKSFKQVAKNSPIAAIDLCIFNEAKEILLGKRINPPAKSFFFVPGGRIRKGE
CEEEEECCCHHHHHHHCCCCCEEEEEEEHHHHHHHHHCCCCCCCCCEEEECCCCCEECCC
TLFISTKRILNNEMNYEITEKDFNTFSLLGVFQHFYNDNFCGNKQFSSHYVVIVYLVPLK
EEEEEHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEHHHH
ILKKSKFGNFKDQHDEYIWYNKTTHENLLIHPYCKEYFKKL
HHHHCCCCCCCCCCCCEEEEECCCCCCEEECHHHHHHHHCC
>Mature Secondary Structure
MILKMFLNEKSFKQVAKNSPIAAIDLCIFNEAKEILLGKRINPPAKSFFFVPGGRIRKGE
CEEEEECCCHHHHHHHCCCCCEEEEEEEHHHHHHHHHCCCCCCCCCEEEECCCCCEECCC
TLFISTKRILNNEMNYEITEKDFNTFSLLGVFQHFYNDNFCGNKQFSSHYVVIVYLVPLK
EEEEEHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEHHHH
ILKKSKFGNFKDQHDEYIWYNKTTHENLLIHPYCKEYFKKL
HHHHCCCCCCCCCCCCEEEEECCCCCCEEECHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: GDP-mannose; H2O [C]

Specific reaction: GDP-mannose + H2O = GDP + mannose [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9673232; 10222209; 11206551; 11258796 [H]