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The map label for this gene is aroA

Identifier: 123965913

GI number: 123965913

Start: 614775

End: 616091

Strand: Reverse

Name: aroA

Synonym: P9515_06781

Alternate gene names: 123965913

Gene position: 616091-614775 (Counterclockwise)

Preceding gene: 123965920

Following gene: 123965912

Centisome position: 36.15

GC content: 35.84

Gene sequence:

>1317_bases
TTGAATACAAACGATATACGCACCGTTAAAGGTGAAAAGAGTTTACAAGGAACAATAAAAGTCCCTGGAGATAAATCAAT
CTCGCACAGATCTTTAATAATTGGAAGTATTGCAGAAGGTGAAACTAATATTGAAGGTTTTTTATATTCTGAAGACCCAC
TTTCAACTGCTGATTGTCTAAGAAAATTAGGTGTACATATTCCTGAAATTAAAAAGGATCAGCCTTTTACCATTAGAGGT
TTAGGTATTGATGGATTTAGAGAACCTAAAGAAATTCTTAATTGTGGTAATTCAGGTACCACAATGAGATTATTAATGGG
ACTTTTGGCTGGTCAAACAGATAGGAATTTCATATTAACTGGAGACAAATCTCTTAATGAAAGACCAATGGGAAGAGTTA
GTAAGCCACTATCATTAATGGGAGGGAAAATTTATGGAAGAGAAAATGGTACAAAAGCTCCAATTTCCATAACGGGGAAC
AAACTAAAGGGTTGCGTCATTGGAACTCCGGTTGCAAGTGCTCAAGTTAAGTCTGCAATCTTACTAGCAGGGTTAAATGC
CTCTGGAACTACTTCGGTTATTGAACCTGCCTCTTCCAGAGATCATACTGAAAGAATGCTTAAAGCATTCGGGGCTGACA
TAAAAATAAGAGGGGAATTAGGAAGAAATATAGTAATAAAATCAGGTAATAATTTAACCGGTCAAAATATATTGATCCCA
GGAGACATCAGCTCAGCAGCTTTTTGGATGATTGCAGCATCAATAGTGCCTGAATCTGAAATCTTGGTTAAAAATGTAGG
CCTAAATCCAACAAGAACGGGGATATTACATGTTATGGATGAAATGGGATGCGATTATAAAATAATTGAAAAATCAACTA
TTGCAGGCGAACCCATAGGTTCTATAAAGGTAAAATATGTAAGTAATTTGAAACCTTTTAAAGTACAAGGTGATATCCTT
CCAAAACTCATAGACGAAATTCCAATACTTACGGTTGCAGCTTGTTTTTGCAATGGGGTTTCAGAAATTAAAGATGCAAA
AGAATTAAGAGTTAAAGAAACCGACCGATTAAAAGTTATGGCCAGACAACTTAAAAAATTTGGTGCAAATATTACTGAGA
AAGAAGACGGTTTAATAATAACTGGCGAGTCTAAATTCCATTCTGCTGAAGTTGACAGTGAAACTGACCATCGAGTCTCG
ATGAGCCTTGCAATAGCATCACTTTTAGCTAAGGGCTCGACAAGGATTGCAAGAGCAGGGGCTTCTAATGTATCGTATCC
AACTTTTTGGGATGATCTTGAAAAACTAATTAATTAA

Upstream 100 bases:

>100_bases
TAGAAAACAGTTACTTAACTTTGAATATTTTTTTTTAAAAACAAACTTATTGATATTATATATCTAATTAAAAACTTATA
AAATCCAACTAATTATTAAT

Downstream 100 bases:

>100_bases
TCTAATAGAATTGTTTACAGAATTTCAGGAGATTTCAACTCGGGACGGAAGTATTTCTCTTAGGAGTCTTTTTTTTCAAG
AGAATTTTCATAGCCTTGAA

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS

Number of amino acids: Translated: 438; Mature: 438

Protein sequence:

>438_residues
MNTNDIRTVKGEKSLQGTIKVPGDKSISHRSLIIGSIAEGETNIEGFLYSEDPLSTADCLRKLGVHIPEIKKDQPFTIRG
LGIDGFREPKEILNCGNSGTTMRLLMGLLAGQTDRNFILTGDKSLNERPMGRVSKPLSLMGGKIYGRENGTKAPISITGN
KLKGCVIGTPVASAQVKSAILLAGLNASGTTSVIEPASSRDHTERMLKAFGADIKIRGELGRNIVIKSGNNLTGQNILIP
GDISSAAFWMIAASIVPESEILVKNVGLNPTRTGILHVMDEMGCDYKIIEKSTIAGEPIGSIKVKYVSNLKPFKVQGDIL
PKLIDEIPILTVAACFCNGVSEIKDAKELRVKETDRLKVMARQLKKFGANITEKEDGLIITGESKFHSAEVDSETDHRVS
MSLAIASLLAKGSTRIARAGASNVSYPTFWDDLEKLIN

Sequences:

>Translated_438_residues
MNTNDIRTVKGEKSLQGTIKVPGDKSISHRSLIIGSIAEGETNIEGFLYSEDPLSTADCLRKLGVHIPEIKKDQPFTIRG
LGIDGFREPKEILNCGNSGTTMRLLMGLLAGQTDRNFILTGDKSLNERPMGRVSKPLSLMGGKIYGRENGTKAPISITGN
KLKGCVIGTPVASAQVKSAILLAGLNASGTTSVIEPASSRDHTERMLKAFGADIKIRGELGRNIVIKSGNNLTGQNILIP
GDISSAAFWMIAASIVPESEILVKNVGLNPTRTGILHVMDEMGCDYKIIEKSTIAGEPIGSIKVKYVSNLKPFKVQGDIL
PKLIDEIPILTVAACFCNGVSEIKDAKELRVKETDRLKVMARQLKKFGANITEKEDGLIITGESKFHSAEVDSETDHRVS
MSLAIASLLAKGSTRIARAGASNVSYPTFWDDLEKLIN
>Mature_438_residues
MNTNDIRTVKGEKSLQGTIKVPGDKSISHRSLIIGSIAEGETNIEGFLYSEDPLSTADCLRKLGVHIPEIKKDQPFTIRG
LGIDGFREPKEILNCGNSGTTMRLLMGLLAGQTDRNFILTGDKSLNERPMGRVSKPLSLMGGKIYGRENGTKAPISITGN
KLKGCVIGTPVASAQVKSAILLAGLNASGTTSVIEPASSRDHTERMLKAFGADIKIRGELGRNIVIKSGNNLTGQNILIP
GDISSAAFWMIAASIVPESEILVKNVGLNPTRTGILHVMDEMGCDYKIIEKSTIAGEPIGSIKVKYVSNLKPFKVQGDIL
PKLIDEIPILTVAACFCNGVSEIKDAKELRVKETDRLKVMARQLKKFGANITEKEDGLIITGESKFHSAEVDSETDHRVS
MSLAIASLLAKGSTRIARAGASNVSYPTFWDDLEKLIN

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family

Homologues:

Organism=Escherichia coli, GI1787137, Length=437, Percent_Identity=28.3752860411899, Blast_Score=125, Evalue=6e-30,
Organism=Saccharomyces cerevisiae, GI6320332, Length=466, Percent_Identity=25.5364806866953, Blast_Score=116, Evalue=8e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROA_PROM5 (A2BVS6)

Other databases:

- EMBL:   CP000552
- RefSeq:   YP_001010994.1
- ProteinModelPortal:   A2BVS6
- SMR:   A2BVS6
- STRING:   A2BVS6
- GeneID:   4719556
- GenomeReviews:   CP000552_GR
- KEGG:   pmc:P9515_06781
- eggNOG:   COG0128
- HOGENOM:   HBG646626
- OMA:   LSRNHTE
- ProtClustDB:   PRK02427
- BioCyc:   PMAR167542:P9515ORF_0714-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00210
- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792
- Gene3D:   G3DSA:3.65.10.10
- PIRSF:   PIRSF000505
- TIGRFAMs:   TIGR01356

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.19

Molecular weight: Translated: 47184; Mature: 47184

Theoretical pI: Translated: 9.16; Mature: 9.16

Prosite motif: PS00104 EPSP_SYNTHASE_1; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTNDIRTVKGEKSLQGTIKVPGDKSISHRSLIIGSIAEGETNIEGFLYSEDPLSTADCL
CCCCCCEEECCCCCCCEEEECCCCCCCCCCEEEEEEECCCCCCCCEEEECCCCCCHHHHH
RKLGVHIPEIKKDQPFTIRGLGIDGFREPKEILNCGNSGTTMRLLMGLLAGQTDRNFILT
HHHCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHCCCCCHHHHHHHHHHCCCCCCCEEEE
GDKSLNERPMGRVSKPLSLMGGKIYGRENGTKAPISITGNKLKGCVIGTPVASAQVKSAI
CCCCCCCCCCCHHCCCHHHHCCEEEECCCCCCCCEEEECCCCCEEEEECCCCHHHHHCEE
LLAGLNASGTTSVIEPASSRDHTERMLKAFGADIKIRGELGRNIVIKSGNNLTGQNILIP
EEEECCCCCCCHHCCCCCCCHHHHHHHHHHCCCEEEEECCCCEEEEECCCCCCCCEEEEC
GDISSAAFWMIAASIVPESEILVKNVGLNPTRTGILHVMDEMGCDYKIIEKSTIAGEPIG
CCCCHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCC
SIKVKYVSNLKPFKVQGDILPKLIDEIPILTVAACFCNGVSEIKDAKELRVKETDRLKVM
CEEEEEECCCCCEEECCCHHHHHHHHCHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHH
ARQLKKFGANITEKEDGLIITGESKFHSAEVDSETDHRVSMSLAIASLLAKGSTRIARAG
HHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEECC
ASNVSYPTFWDDLEKLIN
CCCCCCCCHHHHHHHHCC
>Mature Secondary Structure
MNTNDIRTVKGEKSLQGTIKVPGDKSISHRSLIIGSIAEGETNIEGFLYSEDPLSTADCL
CCCCCCEEECCCCCCCEEEECCCCCCCCCCEEEEEEECCCCCCCCEEEECCCCCCHHHHH
RKLGVHIPEIKKDQPFTIRGLGIDGFREPKEILNCGNSGTTMRLLMGLLAGQTDRNFILT
HHHCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHCCCCCHHHHHHHHHHCCCCCCCEEEE
GDKSLNERPMGRVSKPLSLMGGKIYGRENGTKAPISITGNKLKGCVIGTPVASAQVKSAI
CCCCCCCCCCCHHCCCHHHHCCEEEECCCCCCCCEEEECCCCCEEEEECCCCHHHHHCEE
LLAGLNASGTTSVIEPASSRDHTERMLKAFGADIKIRGELGRNIVIKSGNNLTGQNILIP
EEEECCCCCCCHHCCCCCCCHHHHHHHHHHCCCEEEEECCCCEEEEECCCCCCCCEEEEC
GDISSAAFWMIAASIVPESEILVKNVGLNPTRTGILHVMDEMGCDYKIIEKSTIAGEPIG
CCCCHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCC
SIKVKYVSNLKPFKVQGDILPKLIDEIPILTVAACFCNGVSEIKDAKELRVKETDRLKVM
CEEEEEECCCCCEEECCCHHHHHHHHCHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHH
ARQLKKFGANITEKEDGLIITGESKFHSAEVDSETDHRVSMSLAIASLLAKGSTRIARAG
HHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEECC
ASNVSYPTFWDDLEKLIN
CCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA