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The map label for this gene is frr [H]

Identifier: 123965820

GI number: 123965820

Start: 523337

End: 523885

Strand: Reverse

Name: frr [H]

Synonym: P9515_05851

Alternate gene names: 123965820

Gene position: 523885-523337 (Counterclockwise)

Preceding gene: 123965821

Following gene: 123965819

Centisome position: 30.74

GC content: 32.79

Gene sequence:

>549_bases
ATGAAAGAACAAGAAATTCAATCAAGTATGAATAAAAGTGTTGAGGCCACTCAAAGAAACTTTAATACAATAAGGACTGG
GAGAGCTAACGCTTCCTTACTAGACCGAATTAGTGTTGAATACTACGGAGCAGAAACTCCCATAAAATCGTTAGCCTCTA
TAGCTACTGTCGATTCACAAACAATTTCAATACAGCCATTTGATATTTCTTGCTTACAAGCTATAGAGAAAGCAATATCA
ATGAGTGACTTAGGGATCACCCCTAATAACGATGGAAAAGTAATAAGAATAAATGTCCCCCCTTTAACTGAAGAAAGAAG
AAAAGAGTTTTGCAAGTTGGCTTCGAAATATGCAGAGGAAGGTAAAGTAGCCCTCAGAAATATAAGAAGAGATGCTGTTG
ATAAAGAAAAAAAAGATGAAAAGGAAGGTTTAATATCAATAGATGAATCAAGGGATAACCAATTAGAAATACAAAAATTT
ACTGACAAATATATTTCTTTAATAGAAACTAAACTATCTGAAAAAGAGAAAGAGATACTTAAAGTTTGA

Upstream 100 bases:

>100_bases
TTTTTGATATCTTCAAAAAAGGGAACATCTCGAGAGCTGTTGCTGGAGAGTCCATAGGATCTTTAATAAGTTAAAACTTA
TTTTAATTACTTTTTTAATT

Downstream 100 bases:

>100_bases
AGGAATTTGACGCCATAATAATTGGAGGTGGTTTATCTGGATCTTCAACAGCTCTAAACCTATCAAAAAAAGGTTATTCA
GTTTTAATTATAGAAAAGGA

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor [H]

Number of amino acids: Translated: 182; Mature: 182

Protein sequence:

>182_residues
MKEQEIQSSMNKSVEATQRNFNTIRTGRANASLLDRISVEYYGAETPIKSLASIATVDSQTISIQPFDISCLQAIEKAIS
MSDLGITPNNDGKVIRINVPPLTEERRKEFCKLASKYAEEGKVALRNIRRDAVDKEKKDEKEGLISIDESRDNQLEIQKF
TDKYISLIETKLSEKEKEILKV

Sequences:

>Translated_182_residues
MKEQEIQSSMNKSVEATQRNFNTIRTGRANASLLDRISVEYYGAETPIKSLASIATVDSQTISIQPFDISCLQAIEKAIS
MSDLGITPNNDGKVIRINVPPLTEERRKEFCKLASKYAEEGKVALRNIRRDAVDKEKKDEKEGLISIDESRDNQLEIQKF
TDKYISLIETKLSEKEKEILKV
>Mature_182_residues
MKEQEIQSSMNKSVEATQRNFNTIRTGRANASLLDRISVEYYGAETPIKSLASIATVDSQTISIQPFDISCLQAIEKAIS
MSDLGITPNNDGKVIRINVPPLTEERRKEFCKLASKYAEEGKVALRNIRRDAVDKEKKDEKEGLISIDESRDNQLEIQKF
TDKYISLIETKLSEKEKEILKV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another [H]

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family [H]

Homologues:

Organism=Homo sapiens, GI20270317, Length=178, Percent_Identity=27.5280898876405, Blast_Score=68, Evalue=4e-12,
Organism=Escherichia coli, GI1786368, Length=180, Percent_Identity=49.4444444444444, Blast_Score=164, Evalue=2e-42,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002661
- InterPro:   IPR015998 [H]

Pfam domain/function: PF01765 RRF [H]

EC number: NA

Molecular weight: Translated: 20613; Mature: 20613

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEQEIQSSMNKSVEATQRNFNTIRTGRANASLLDRISVEYYGAETPIKSLASIATVDSQ
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHEECCCCHHHHHHHHHHCCCC
TISIQPFDISCLQAIEKAISMSDLGITPNNDGKVIRINVPPLTEERRKEFCKLASKYAEE
EEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHH
GKVALRNIRRDAVDKEKKDEKEGLISIDESRDNQLEIQKFTDKYISLIETKLSEKEKEIL
HHHHHHHHHHHHHCHHHHHHHCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
KV
CC
>Mature Secondary Structure
MKEQEIQSSMNKSVEATQRNFNTIRTGRANASLLDRISVEYYGAETPIKSLASIATVDSQ
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHEECCCCHHHHHHHHHHCCCC
TISIQPFDISCLQAIEKAISMSDLGITPNNDGKVIRINVPPLTEERRKEFCKLASKYAEE
EEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHH
GKVALRNIRRDAVDKEKKDEKEGLISIDESRDNQLEIQKFTDKYISLIETKLSEKEKEIL
HHHHHHHHHHHHHCHHHHHHHCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
KV
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA