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The map label for this gene is phhB

Identifier: 123965790

GI number: 123965790

Start: 495350

End: 495640

Strand: Reverse

Name: phhB

Synonym: P9515_05551

Alternate gene names: NA

Gene position: 495640-495350 (Counterclockwise)

Preceding gene: 123965791

Following gene: 123965789

Centisome position: 29.08

GC content: 28.52

Gene sequence:

>291_bases
ATGAAACCACACCTTCTACAAAATGAGGAATTAAAAGAACTAATTGCCAAAATACCCGGATGGGAAATCATCTCAAATCA
CTTAGAAAGAGAGTTTAATTTTGGTGACTTTATAGAAGCTTTTTCCTTTATGACAAAGATTGCTTTAATTTGTGAAAAAT
ATAATCATCATCCCAATTGGGAAAATGTCTATTCGAAAGTAATTATTAAACTAAGTACACATGATTTAGGAGGTATTACA
AATTTAGATCAGAAAATTGCTTCGGAAATTAATGAAATTTTCGAAAAATAA

Upstream 100 bases:

>100_bases
GGAACATCGATTTAGTAAAAAAGAAAGAATTATAAGTGTTCATATTATTGGTTCAAAAAGTTAAAATATCTATAATGATA
TTCAGCAATATTAAATATAA

Downstream 100 bases:

>100_bases
TTTAATATAGAATTACTTTATTCTTTCAAAAGATCATAATTTAAATGATTGAAAAATTGATACCTGTAACCATTATTAGT
GGATTCTTGGGATCAGGGAA

Product: pterin-4-alpha-carbinolamine dehydratase

Products: NA

Alternate protein names: PHS; 4-alpha-hydroxy-tetrahydropterin dehydratase; Pterin carbinolamine dehydratase; PCD

Number of amino acids: Translated: 96; Mature: 96

Protein sequence:

>96_residues
MKPHLLQNEELKELIAKIPGWEIISNHLEREFNFGDFIEAFSFMTKIALICEKYNHHPNWENVYSKVIIKLSTHDLGGIT
NLDQKIASEINEIFEK

Sequences:

>Translated_96_residues
MKPHLLQNEELKELIAKIPGWEIISNHLEREFNFGDFIEAFSFMTKIALICEKYNHHPNWENVYSKVIIKLSTHDLGGIT
NLDQKIASEINEIFEK
>Mature_96_residues
MKPHLLQNEELKELIAKIPGWEIISNHLEREFNFGDFIEAFSFMTKIALICEKYNHHPNWENVYSKVIIKLSTHDLGGIT
NLDQKIASEINEIFEK

Specific function: Unknown

COG id: COG2154

COG function: function code H; Pterin-4a-carbinolamine dehydratase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pterin-4-alpha-carbinolamine dehydratase family

Homologues:

Organism=Homo sapiens, GI134133240, Length=89, Percent_Identity=44.9438202247191, Blast_Score=77, Evalue=3e-15,
Organism=Homo sapiens, GI4557831, Length=96, Percent_Identity=41.6666666666667, Blast_Score=76, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI115533705, Length=97, Percent_Identity=45.360824742268, Blast_Score=88, Evalue=8e-19,
Organism=Drosophila melanogaster, GI45549100, Length=84, Percent_Identity=42.8571428571429, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PHS_PROM5 (A2BVF3)

Other databases:

- EMBL:   CP000552
- RefSeq:   YP_001010871.1
- ProteinModelPortal:   A2BVF3
- SMR:   A2BVF3
- STRING:   A2BVF3
- GeneID:   4719773
- GenomeReviews:   CP000552_GR
- KEGG:   pmc:P9515_05551
- eggNOG:   COG2154
- HOGENOM:   HBG705804
- OMA:   IALICEK
- ProtClustDB:   PRK00823
- BioCyc:   PMAR167542:P9515ORF_0591-MONOMER
- HAMAP:   MF_00434
- InterPro:   IPR001533
- Gene3D:   G3DSA:3.30.1360.20
- PANTHER:   PTHR12599

Pfam domain/function: PF01329 Pterin_4a; SSF55248 Trans_pterinDh

EC number: =4.2.1.96

Molecular weight: Translated: 11255; Mature: 11255

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPHLLQNEELKELIAKIPGWEIISNHLEREFNFGDFIEAFSFMTKIALICEKYNHHPNW
CCCCCCCCHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCH
ENVYSKVIIKLSTHDLGGITNLDQKIASEINEIFEK
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKPHLLQNEELKELIAKIPGWEIISNHLEREFNFGDFIEAFSFMTKIALICEKYNHHPNW
CCCCCCCCHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCH
ENVYSKVIIKLSTHDLGGITNLDQKIASEINEIFEK
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA