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The map label for this gene is argS [H]

Identifier: 123965451

GI number: 123965451

Start: 195576

End: 197384

Strand: Reverse

Name: argS [H]

Synonym: P9515_02161

Alternate gene names: 123965451

Gene position: 197384-195576 (Counterclockwise)

Preceding gene: 123965452

Following gene: 123965450

Centisome position: 11.58

GC content: 28.25

Gene sequence:

>1809_bases
ATGCAGGTAATTTATCAAGAATTAACTAAAAGATTTGAAGAAACCCTTCTAGAAAGTCTTATAAAAAATGAGAAGAAAGA
AGAATTTGAAAACATTCGTAAAAATCTAATAAATCAAGCATCAAAAGAAGAATTTGGTGATTATCAATGCAATATATGTC
TAGTTTTATCTAAAATTTATAAAAGGAATCCACGAGAAATTGCAATTGAATTTGTTCAGAAACTAAAAGAAAACAAAGAG
ATATCTAATTTATGTGAAGCTTTAGAAATTGCGGGGCCAGGTTTTATAAATATAAAATTAAAAAATAATCTTTTAATTGC
AAAAATAAAATCGAACATTAAATGCCCTAGAGCTGGTGTTCCATTATCAAATAATAATAGTCATTCCCAAAAAAAAGTTA
TCGTAGATTTTTCAAGTCCTAATATCGCTAAAGAAATGCATGTAGGTCATTTAAGATCAACAATTATAGGCGATTCGATT
GCAAAAATTTTTGAATTAAGAGGATACACCGTACTCAGGTTAAATCATGTTGGAGATTGGGGTACTCAATTTGGAATGCT
TATTACTCAGCTTAAAGATTTATATTCAAGTGATCTTAGAGAAATAGATAAGATCACAATTAGTGATTTAGTTGAATTTT
ATAAAGCTTCAAAAAAAAGATTTGATAATGAAACAGAATTTAAAAAAAGATCAAGAGAAGAGGTAGTTAAATTACAAAGT
GGGGATAAAAAATCAATTAAAGCTTGGAAATTATTATGTAACCAATCAAGAAAAGAGTTCGATGAAATCTATAAAATATT
GAATATAAAAATTAAGGAAAGAGGAGAATCTTTTTATAATCCCTTTCTAAAATCAATTATTGAAGATTTAACTTTTAAGA
AGATTTTAGTAGAAGATCAAGGAGCTAAATGTGTTTTTCTTCATGGCATGACCAATAAAGAAGGTAATCCATTACCACTA
ATTATTAAAAAAAAAGACGGTGGATTCAATTATGCTACTACTGATCTTGCTGCTCTAAGATATCGATTTAGGAAGGAACC
TCATGGGGATAATGCAACTAGAATTATTTATGTAACAGATCATGGTCAATCGAATCATTTTGCAGGAGTTTTTCAAGTAG
CTAAAAGAGCTAATTGGATCCCTGAAGACTGTGAAGTGAATCACGTACCATTTGGACTAGTACAAGGAATTGATGGTAAA
AAATTAAAAACAAGAGAAGGAGACATCATAAAACTAAAAGATTTATTATCAGAGTCAATTAAAAGAGCCAAAGAAGATCT
CTTGAAAAGATTAGAGAAGGAAAGTCGTTTTGAAACTGAAGAGTTTATTTTAAATACTTCAAAAGTTATTGGAATTGGAG
CAGTTAAATATGCTGATTTAAGCCAAAATAGAATAACAAATTATCAATTTAGTTTTGAAAAGATGCTTTCTTTAAATGGC
AATACGGCGCCATATCTTTTATATACGCTTGTAAGAATTTCAGGAATTAATAGAAAAAATAATATGAATGAAGATGCTGT
GAATTCGGAATCTATTGCATATAGCCATGATCTAGAGTGGAAACTAATAAGAAAATTACTTAAATTTGATGAGGTTATAG
TTTCTATAGAAAAAGATTTGATGCCAAATAGACTCTGTAATTATCTTTTTGAATTATGTCAGTCGTTTAATCGATTTTAT
GATCAAGTATCTATTCTGAAGGTTGAAATGAATACAAAGATTTCAAGACTTACATTATGTGCTTTGACTGAAAAGACTTT
AAAATTAAGTTTAGAACTTCTTGGAATTGATTCCTTAGAGAGAATGTAA

Upstream 100 bases:

>100_bases
TGATTTCATATCGACAAGTTCTTCAATTACTAAAAGTAATTGGATTGATTTTAGTATGCGTTATATTAATTAAATGAATC
GAATTGTACTTTAATAATTC

Downstream 100 bases:

>100_bases
TGAGTGAATTTAATAAAATAAATAATCTTCCCCCTACTCCAAGAAAGGAAATAATAAATATGCAATCTTATTCTGCACCA
TTAGAAAACAGAAGAAATTT

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS [H]

Number of amino acids: Translated: 602; Mature: 602

Protein sequence:

>602_residues
MQVIYQELTKRFEETLLESLIKNEKKEEFENIRKNLINQASKEEFGDYQCNICLVLSKIYKRNPREIAIEFVQKLKENKE
ISNLCEALEIAGPGFINIKLKNNLLIAKIKSNIKCPRAGVPLSNNNSHSQKKVIVDFSSPNIAKEMHVGHLRSTIIGDSI
AKIFELRGYTVLRLNHVGDWGTQFGMLITQLKDLYSSDLREIDKITISDLVEFYKASKKRFDNETEFKKRSREEVVKLQS
GDKKSIKAWKLLCNQSRKEFDEIYKILNIKIKERGESFYNPFLKSIIEDLTFKKILVEDQGAKCVFLHGMTNKEGNPLPL
IIKKKDGGFNYATTDLAALRYRFRKEPHGDNATRIIYVTDHGQSNHFAGVFQVAKRANWIPEDCEVNHVPFGLVQGIDGK
KLKTREGDIIKLKDLLSESIKRAKEDLLKRLEKESRFETEEFILNTSKVIGIGAVKYADLSQNRITNYQFSFEKMLSLNG
NTAPYLLYTLVRISGINRKNNMNEDAVNSESIAYSHDLEWKLIRKLLKFDEVIVSIEKDLMPNRLCNYLFELCQSFNRFY
DQVSILKVEMNTKISRLTLCALTEKTLKLSLELLGIDSLERM

Sequences:

>Translated_602_residues
MQVIYQELTKRFEETLLESLIKNEKKEEFENIRKNLINQASKEEFGDYQCNICLVLSKIYKRNPREIAIEFVQKLKENKE
ISNLCEALEIAGPGFINIKLKNNLLIAKIKSNIKCPRAGVPLSNNNSHSQKKVIVDFSSPNIAKEMHVGHLRSTIIGDSI
AKIFELRGYTVLRLNHVGDWGTQFGMLITQLKDLYSSDLREIDKITISDLVEFYKASKKRFDNETEFKKRSREEVVKLQS
GDKKSIKAWKLLCNQSRKEFDEIYKILNIKIKERGESFYNPFLKSIIEDLTFKKILVEDQGAKCVFLHGMTNKEGNPLPL
IIKKKDGGFNYATTDLAALRYRFRKEPHGDNATRIIYVTDHGQSNHFAGVFQVAKRANWIPEDCEVNHVPFGLVQGIDGK
KLKTREGDIIKLKDLLSESIKRAKEDLLKRLEKESRFETEEFILNTSKVIGIGAVKYADLSQNRITNYQFSFEKMLSLNG
NTAPYLLYTLVRISGINRKNNMNEDAVNSESIAYSHDLEWKLIRKLLKFDEVIVSIEKDLMPNRLCNYLFELCQSFNRFY
DQVSILKVEMNTKISRLTLCALTEKTLKLSLELLGIDSLERM
>Mature_602_residues
MQVIYQELTKRFEETLLESLIKNEKKEEFENIRKNLINQASKEEFGDYQCNICLVLSKIYKRNPREIAIEFVQKLKENKE
ISNLCEALEIAGPGFINIKLKNNLLIAKIKSNIKCPRAGVPLSNNNSHSQKKVIVDFSSPNIAKEMHVGHLRSTIIGDSI
AKIFELRGYTVLRLNHVGDWGTQFGMLITQLKDLYSSDLREIDKITISDLVEFYKASKKRFDNETEFKKRSREEVVKLQS
GDKKSIKAWKLLCNQSRKEFDEIYKILNIKIKERGESFYNPFLKSIIEDLTFKKILVEDQGAKCVFLHGMTNKEGNPLPL
IIKKKDGGFNYATTDLAALRYRFRKEPHGDNATRIIYVTDHGQSNHFAGVFQVAKRANWIPEDCEVNHVPFGLVQGIDGK
KLKTREGDIIKLKDLLSESIKRAKEDLLKRLEKESRFETEEFILNTSKVIGIGAVKYADLSQNRITNYQFSFEKMLSLNG
NTAPYLLYTLVRISGINRKNNMNEDAVNSESIAYSHDLEWKLIRKLLKFDEVIVSIEKDLMPNRLCNYLFELCQSFNRFY
DQVSILKVEMNTKISRLTLCALTEKTLKLSLELLGIDSLERM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI15149476, Length=596, Percent_Identity=43.6241610738255, Blast_Score=448, Evalue=1e-126,
Organism=Homo sapiens, GI197100773, Length=581, Percent_Identity=29.9483648881239, Blast_Score=219, Evalue=4e-57,
Organism=Escherichia coli, GI1788184, Length=571, Percent_Identity=39.7548161120841, Blast_Score=437, Evalue=1e-123,
Organism=Caenorhabditis elegans, GI71985061, Length=608, Percent_Identity=39.6381578947368, Blast_Score=404, Evalue=1e-113,
Organism=Caenorhabditis elegans, GI71985068, Length=569, Percent_Identity=40.597539543058, Blast_Score=390, Evalue=1e-108,
Organism=Caenorhabditis elegans, GI17532153, Length=500, Percent_Identity=25.4, Blast_Score=128, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6320548, Length=563, Percent_Identity=31.2611012433393, Blast_Score=218, Evalue=2e-57,
Organism=Saccharomyces cerevisiae, GI6321883, Length=567, Percent_Identity=28.2186948853616, Blast_Score=201, Evalue=2e-52,
Organism=Drosophila melanogaster, GI18859963, Length=613, Percent_Identity=42.2512234910277, Blast_Score=434, Evalue=1e-121,
Organism=Drosophila melanogaster, GI28571570, Length=489, Percent_Identity=29.2433537832311, Blast_Score=184, Evalue=2e-46,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d [H]

EC number: =6.1.1.19 [H]

Molecular weight: Translated: 69559; Mature: 69559

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVIYQELTKRFEETLLESLIKNEKKEEFENIRKNLINQASKEEFGDYQCNICLVLSKIY
CCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
KRNPREIAIEFVQKLKENKEISNLCEALEIAGPGFINIKLKNNLLIAKIKSNIKCPRAGV
HCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEEEECCEEEEEECCCCCCCCCCC
PLSNNNSHSQKKVIVDFSSPNIAKEMHVGHLRSTIIGDSIAKIFELRGYTVLRLNHVGDW
CCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCC
GTQFGMLITQLKDLYSSDLREIDKITISDLVEFYKASKKRFDNETEFKKRSREEVVKLQS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC
GDKKSIKAWKLLCNQSRKEFDEIYKILNIKIKERGESFYNPFLKSIIEDLTFKKILVEDQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHEEECC
GAKCVFLHGMTNKEGNPLPLIIKKKDGGFNYATTDLAALRYRFRKEPHGDNATRIIYVTD
CCCEEEEECCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEEE
HGQSNHFAGVFQVAKRANWIPEDCEVNHVPFGLVQGIDGKKLKTREGDIIKLKDLLSESI
CCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHCCCCCCEEECCCCCEEHHHHHHHHHH
KRAKEDLLKRLEKESRFETEEFILNTSKVIGIGAVKYADLSQNRITNYQFSFEKMLSLNG
HHHHHHHHHHHHHHHCCCHHHHHHCCCCEEEECCEEECCCCCCCCCCCEEHHHHHHHCCC
NTAPYLLYTLVRISGINRKNNMNEDAVNSESIAYSHDLEWKLIRKLLKFDEVIVSIEKDL
CCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHC
MPNRLCNYLFELCQSFNRFYDQVSILKVEMNTKISRLTLCALTEKTLKLSLELLGIDSLE
CHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHEECCHHHH
RM
CC
>Mature Secondary Structure
MQVIYQELTKRFEETLLESLIKNEKKEEFENIRKNLINQASKEEFGDYQCNICLVLSKIY
CCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
KRNPREIAIEFVQKLKENKEISNLCEALEIAGPGFINIKLKNNLLIAKIKSNIKCPRAGV
HCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEEEECCEEEEEECCCCCCCCCCC
PLSNNNSHSQKKVIVDFSSPNIAKEMHVGHLRSTIIGDSIAKIFELRGYTVLRLNHVGDW
CCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCC
GTQFGMLITQLKDLYSSDLREIDKITISDLVEFYKASKKRFDNETEFKKRSREEVVKLQS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC
GDKKSIKAWKLLCNQSRKEFDEIYKILNIKIKERGESFYNPFLKSIIEDLTFKKILVEDQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHEEECC
GAKCVFLHGMTNKEGNPLPLIIKKKDGGFNYATTDLAALRYRFRKEPHGDNATRIIYVTD
CCCEEEEECCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEEE
HGQSNHFAGVFQVAKRANWIPEDCEVNHVPFGLVQGIDGKKLKTREGDIIKLKDLLSESI
CCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHCCCCCCEEECCCCCEEHHHHHHHHHH
KRAKEDLLKRLEKESRFETEEFILNTSKVIGIGAVKYADLSQNRITNYQFSFEKMLSLNG
HHHHHHHHHHHHHHHCCCHHHHHHCCCCEEEECCEEECCCCCCCCCCCEEHHHHHHHCCC
NTAPYLLYTLVRISGINRKNNMNEDAVNSESIAYSHDLEWKLIRKLLKFDEVIVSIEKDL
CCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHC
MPNRLCNYLFELCQSFNRFYDQVSILKVEMNTKISRLTLCALTEKTLKLSLELLGIDSLE
CHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHEECCHHHH
RM
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12917642 [H]