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The map label for this gene is dltR [H]

Identifier: 123965433

GI number: 123965433

Start: 180445

End: 181173

Strand: Reverse

Name: dltR [H]

Synonym: P9515_01981

Alternate gene names: 123965433

Gene position: 181173-180445 (Counterclockwise)

Preceding gene: 123965435

Following gene: 123965431

Centisome position: 10.63

GC content: 35.94

Gene sequence:

>729_bases
ATGAACGATACTAATCAAATCAATAATGACACAATTCGAAAATCAAAAATTTTATTGGTAGATGATGAGCCAGGTTTAAG
AACAGCTGTAAAAACATTTCTCGAAGACGAAGGATTTGAAATCTCTATTGCGGTAGACGGAGAGGATGGATGGGAAAAAG
CACAAACAATTTTTCCAGACCTCATTATTAGCGATATTATGATGCCTAGATCAAATGGTTACGCCCTATTAGAAAAAATA
AGAGAAGATGAAAAGCTAGGAGGCACGCCAGTGATTTTTCTGACAGCGAAGGGAATGACTTTGGATAGAACTCAGGGATA
CCTCGCTGGCATTGATGATTATATTGCTAAACCCTTTGATCCAGATGAATTATCTGCAAGAGTTAAAAATGTAATTAATA
GGCAAGAGAGATTACTCAAAGAAGCAGCAAGATTTGCCGATATTGATGTAAGCAAAATGGCAAAACAAATCACTGAAATT
AAATCTATGCTTACAGATCAGAATCCACTAAATCAAGAAAATTCAATAGATATCCCCAACTTTACTCCAAGAGAAGCAAG
TGTACTCCAGCTTGTGGCAGAGGGTCTCATGAACAAAGAAATTGCCAGAAAACTTGAAACCTCTATCAGAAATGTTGAGA
AATACGTAAGCAGGCTGTTTATTAAAACAAGTACATCTAGCAGAACCGAATTAGTCCGTTATGCGCTTGAAAATCATTTA
GTAAAATAA

Upstream 100 bases:

>100_bases
TGTTGAGGATTGATAATCTAGTAGTATAGGAGAAGAAAACATGATATTTATTATATAAAATTATTATTAGGCTAAAGAAA
ATTTAATTCAAAATTTAAAA

Downstream 100 bases:

>100_bases
TTTATTACAACTTCTTAAATTCAATTAATTTAGAAAAATAAAATGGGGCTTGATTCAATTTTTTTTGAACGACAGTAAAA
CCTTTCTCATTAGCAGCATT

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MNDTNQINNDTIRKSKILLVDDEPGLRTAVKTFLEDEGFEISIAVDGEDGWEKAQTIFPDLIISDIMMPRSNGYALLEKI
REDEKLGGTPVIFLTAKGMTLDRTQGYLAGIDDYIAKPFDPDELSARVKNVINRQERLLKEAARFADIDVSKMAKQITEI
KSMLTDQNPLNQENSIDIPNFTPREASVLQLVAEGLMNKEIARKLETSIRNVEKYVSRLFIKTSTSSRTELVRYALENHL
VK

Sequences:

>Translated_242_residues
MNDTNQINNDTIRKSKILLVDDEPGLRTAVKTFLEDEGFEISIAVDGEDGWEKAQTIFPDLIISDIMMPRSNGYALLEKI
REDEKLGGTPVIFLTAKGMTLDRTQGYLAGIDDYIAKPFDPDELSARVKNVINRQERLLKEAARFADIDVSKMAKQITEI
KSMLTDQNPLNQENSIDIPNFTPREASVLQLVAEGLMNKEIARKLETSIRNVEKYVSRLFIKTSTSSRTELVRYALENHL
VK
>Mature_242_residues
MNDTNQINNDTIRKSKILLVDDEPGLRTAVKTFLEDEGFEISIAVDGEDGWEKAQTIFPDLIISDIMMPRSNGYALLEKI
REDEKLGGTPVIFLTAKGMTLDRTQGYLAGIDDYIAKPFDPDELSARVKNVINRQERLLKEAARFADIDVSKMAKQITEI
KSMLTDQNPLNQENSIDIPNFTPREASVLQLVAEGLMNKEIARKLETSIRNVEKYVSRLFIKTSTSSRTELVRYALENHL
VK

Specific function: Member of the two-component regulatory system dltS/dltR. Regulates the expression of the dlt operon [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=119, Percent_Identity=38.655462184874, Blast_Score=87, Evalue=9e-19,
Organism=Escherichia coli, GI2367329, Length=122, Percent_Identity=42.6229508196721, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1786784, Length=151, Percent_Identity=34.4370860927152, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1790860, Length=156, Percent_Identity=30.1282051282051, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1789809, Length=120, Percent_Identity=35.8333333333333, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788394, Length=119, Percent_Identity=34.453781512605, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1790863, Length=123, Percent_Identity=34.1463414634146, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787229, Length=120, Percent_Identity=34.1666666666667, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI87082012, Length=123, Percent_Identity=37.3983739837398, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1786911, Length=145, Percent_Identity=33.1034482758621, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1788550, Length=121, Percent_Identity=34.7107438016529, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787473, Length=219, Percent_Identity=31.9634703196347, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1787375, Length=123, Percent_Identity=29.2682926829268, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1789402, Length=119, Percent_Identity=31.9327731092437, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1790299, Length=125, Percent_Identity=30.4, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1787487, Length=103, Percent_Identity=35.9223300970874, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI1788191, Length=123, Percent_Identity=30.8943089430894, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27394; Mature: 27394

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDTNQINNDTIRKSKILLVDDEPGLRTAVKTFLEDEGFEISIAVDGEDGWEKAQTIFPD
CCCCCCCCCCHHHHCEEEEEECCCCHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHH
LIISDIMMPRSNGYALLEKIREDEKLGGTPVIFLTAKGMTLDRTQGYLAGIDDYIAKPFD
HHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCEECCCCCHHHCCHHHHCCCCC
PDELSARVKNVINRQERLLKEAARFADIDVSKMAKQITEIKSMLTDQNPLNQENSIDIPN
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
FTPREASVLQLVAEGLMNKEIARKLETSIRNVEKYVSRLFIKTSTSSRTELVRYALENHL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHC
VK
CC
>Mature Secondary Structure
MNDTNQINNDTIRKSKILLVDDEPGLRTAVKTFLEDEGFEISIAVDGEDGWEKAQTIFPD
CCCCCCCCCCHHHHCEEEEEECCCCHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHH
LIISDIMMPRSNGYALLEKIREDEKLGGTPVIFLTAKGMTLDRTQGYLAGIDDYIAKPFD
HHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCEECCCCCHHHCCHHHHCCCCC
PDELSARVKNVINRQERLLKEAARFADIDVSKMAKQITEIKSMLTDQNPLNQENSIDIPN
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
FTPREASVLQLVAEGLMNKEIARKLETSIRNVEKYVSRLFIKTSTSSRTELVRYALENHL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHC
VK
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11591677; 12354221 [H]