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The map label for this gene is sucC

Identifier: 121999019

GI number: 121999019

Start: 2455080

End: 2456255

Strand: Reverse

Name: sucC

Synonym: Hhal_2240

Alternate gene names: 121999019

Gene position: 2456255-2455080 (Counterclockwise)

Preceding gene: 121999021

Following gene: 121999018

Centisome position: 91.7

GC content: 69.13

Gene sequence:

>1176_bases
ATGAATCTTCATGAGTTCCAGGCCAAGCACCTCTTCACCGAGGCGGGGATCGCCATCCCCCGCGGGTATGTGGCGCGCTC
CAGCGCCGAGGCCCGTGCCGCTGCCGAGCGGCTCGGTGGCTCGGCCTGGGTGGTCAAGGCCCAGGTCCACGCCGGGGGGC
GCGGCAAGGCCGGTGGCGTCCGGGTGATCCAGGAGGGCGACGAGATCGAGCGCTACGCCGACTCGCTGCTGGGCGAGCGG
TTGGTCACCCACCAGACCGATGGGCGCGGGCAGCCGATCCACGCCCTGCTGGTCGAAGAGGGTCTGGAGATCGCCCGCGA
ACTCTACCTGGGCGCCCTGGTCGACCGGGCCAGCCAGCGGGTGGTCTTCATGGTCTCGGCCGCCGGCGGTATGGATATCG
AGGAGGTGGCGGCCAGCGAGCCCGAGCGCATCCACACCGTGCGGGTCCATCCGGCCGCCGGGCTGCAGCCGTACCAGTGC
CGTCAGCTGGGGTTCGCCCTGGGCCTCGACAAGGCCCAGGTGGGGGATCTGACGCGGATGATGCAGGGGCTCTACCGCCT
GTTCCTGGAGCGCGATCTGTCGCTGGTCGAGATCAACCCGCTGATCGTCACCGGGGAGGGCCGGCTGCTGGCCCTGGATG
CCAAGGTGACCGTGGACGACAACGCCGTGGAGATCGGCCGGCAGTCGCAGATCCAGGACATGCGCGACCTCACCCAGGAG
GACGAGACCGAGGTCCGGGCCGCCGAGCACAACCTCAACTACATCACCCTGGACGGCAACATCGGCTGCATGGTCAACGG
GGCCGGTCTGGCCATGGCCACCATGGACGTGATCAAGCTCCACGGCGGGGCCCCGGCCAACTTCCTCGATGTCGGCGGCG
GTACGAACGCCGAGCGGGTGGCCGAGGCCTTCAAGATCATCCTCTCCAGCCCCTCGGTGGAGGGCATCCTGGTGAACATC
TTCGGCGGGATCGTCCGCTGCGACATGATCGCCGAGGGCATCGTGGCCGCGGTGCAGGACGTCGGGGTGGAGGTCCCCGT
CGTCGTCCGGCTGGAGGGCACCAACGTCGAGCAGGGCAAGCAGATCCTCGCCGACAGCGGGCTCGACCTCATCCCCGCCG
ACGACTTGGCGGATGCCGCCGCCAAGATTGTCGATATCGCCGGTCAGGTGGCCTGA

Upstream 100 bases:

>100_bases
CAACCAAATTGGCACGGCCGGACGGTTTTGAAAAGCGCCGGCCGCTGAACCACTATAATCGACCGCCCGGCGACCGCGAC
CCCATGGGAGGAGCTGTTCA

Downstream 100 bases:

>100_bases
GCCCCAGGCAAGAGAGGAGCAGAACATGAGCATTCTCGTCGACCAGAGCACCCGGGTGCTCGTGCAGGGGTTCACCGGCA
AGCAGGGGACCTTCCACGCG

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MNLHEFQAKHLFTEAGIAIPRGYVARSSAEARAAAERLGGSAWVVKAQVHAGGRGKAGGVRVIQEGDEIERYADSLLGER
LVTHQTDGRGQPIHALLVEEGLEIARELYLGALVDRASQRVVFMVSAAGGMDIEEVAASEPERIHTVRVHPAAGLQPYQC
RQLGFALGLDKAQVGDLTRMMQGLYRLFLERDLSLVEINPLIVTGEGRLLALDAKVTVDDNAVEIGRQSQIQDMRDLTQE
DETEVRAAEHNLNYITLDGNIGCMVNGAGLAMATMDVIKLHGGAPANFLDVGGGTNAERVAEAFKIILSSPSVEGILVNI
FGGIVRCDMIAEGIVAAVQDVGVEVPVVVRLEGTNVEQGKQILADSGLDLIPADDLADAAAKIVDIAGQVA

Sequences:

>Translated_391_residues
MNLHEFQAKHLFTEAGIAIPRGYVARSSAEARAAAERLGGSAWVVKAQVHAGGRGKAGGVRVIQEGDEIERYADSLLGER
LVTHQTDGRGQPIHALLVEEGLEIARELYLGALVDRASQRVVFMVSAAGGMDIEEVAASEPERIHTVRVHPAAGLQPYQC
RQLGFALGLDKAQVGDLTRMMQGLYRLFLERDLSLVEINPLIVTGEGRLLALDAKVTVDDNAVEIGRQSQIQDMRDLTQE
DETEVRAAEHNLNYITLDGNIGCMVNGAGLAMATMDVIKLHGGAPANFLDVGGGTNAERVAEAFKIILSSPSVEGILVNI
FGGIVRCDMIAEGIVAAVQDVGVEVPVVVRLEGTNVEQGKQILADSGLDLIPADDLADAAAKIVDIAGQVA
>Mature_391_residues
MNLHEFQAKHLFTEAGIAIPRGYVARSSAEARAAAERLGGSAWVVKAQVHAGGRGKAGGVRVIQEGDEIERYADSLLGER
LVTHQTDGRGQPIHALLVEEGLEIARELYLGALVDRASQRVVFMVSAAGGMDIEEVAASEPERIHTVRVHPAAGLQPYQC
RQLGFALGLDKAQVGDLTRMMQGLYRLFLERDLSLVEINPLIVTGEGRLLALDAKVTVDDNAVEIGRQSQIQDMRDLTQE
DETEVRAAEHNLNYITLDGNIGCMVNGAGLAMATMDVIKLHGGAPANFLDVGGGTNAERVAEAFKIILSSPSVEGILVNI
FGGIVRCDMIAEGIVAAVQDVGVEVPVVVRLEGTNVEQGKQILADSGLDLIPADDLADAAAKIVDIAGQVA

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain

Homologues:

Organism=Homo sapiens, GI11321583, Length=394, Percent_Identity=46.9543147208122, Blast_Score=354, Evalue=8e-98,
Organism=Homo sapiens, GI157779135, Length=388, Percent_Identity=44.8453608247423, Blast_Score=315, Evalue=6e-86,
Organism=Homo sapiens, GI294862256, Length=368, Percent_Identity=44.5652173913043, Blast_Score=295, Evalue=3e-80,
Organism=Escherichia coli, GI1786948, Length=384, Percent_Identity=58.3333333333333, Blast_Score=440, Evalue=1e-125,
Organism=Caenorhabditis elegans, GI17539378, Length=393, Percent_Identity=45.0381679389313, Blast_Score=325, Evalue=3e-89,
Organism=Caenorhabditis elegans, GI17567829, Length=396, Percent_Identity=43.6868686868687, Blast_Score=324, Evalue=4e-89,
Organism=Saccharomyces cerevisiae, GI6321683, Length=397, Percent_Identity=41.8136020151133, Blast_Score=325, Evalue=8e-90,
Organism=Drosophila melanogaster, GI161078106, Length=400, Percent_Identity=46.75, Blast_Score=323, Evalue=2e-88,
Organism=Drosophila melanogaster, GI24645208, Length=400, Percent_Identity=46.75, Blast_Score=323, Evalue=2e-88,
Organism=Drosophila melanogaster, GI281361397, Length=401, Percent_Identity=46.8827930174564, Blast_Score=321, Evalue=4e-88,
Organism=Drosophila melanogaster, GI281361395, Length=401, Percent_Identity=46.8827930174564, Blast_Score=321, Evalue=4e-88,
Organism=Drosophila melanogaster, GI21356231, Length=393, Percent_Identity=45.8015267175573, Blast_Score=317, Evalue=1e-86,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SUCC_HALHL (A1WZ92)

Other databases:

- EMBL:   CP000544
- RefSeq:   YP_001003806.1
- ProteinModelPortal:   A1WZ92
- SMR:   A1WZ92
- STRING:   A1WZ92
- GeneID:   4709505
- GenomeReviews:   CP000544_GR
- KEGG:   hha:Hhal_2240
- eggNOG:   COG0045
- HOGENOM:   HBG315432
- OMA:   RREFYFA
- PhylomeDB:   A1WZ92
- ProtClustDB:   PRK00696
- BioCyc:   HHAL349124:HHAL_2240-MONOMER
- HAMAP:   MF_00558
- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102
- Gene3D:   G3DSA:3.30.1490.20
- Gene3D:   G3DSA:3.30.470.20
- Gene3D:   G3DSA:3.40.50.261
- PANTHER:   PTHR11815
- TIGRFAMs:   TIGR01016

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA; SSF52210 CoA_ligase

EC number: =6.2.1.5

Molecular weight: Translated: 41590; Mature: 41590

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: PS50975 ATP_GRASP; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLHEFQAKHLFTEAGIAIPRGYVARSSAEARAAAERLGGSAWVVKAQVHAGGRGKAGGV
CCCHHHHHHHHHHHCCCCCCCCHHCCCCHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCE
RVIQEGDEIERYADSLLGERLVTHQTDGRGQPIHALLVEEGLEIARELYLGALVDRASQR
EEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCE
VVFMVSAAGGMDIEEVAASEPERIHTVRVHPAAGLQPYQCRQLGFALGLDKAQVGDLTRM
EEEEEECCCCCCHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHHH
MQGLYRLFLERDLSLVEINPLIVTGEGRLLALDAKVTVDDNAVEIGRQSQIQDMRDLTQE
HHHHHHHHHHCCCCEEEECEEEEECCCEEEEEEEEEEECCCHHHCCCHHHHHHHHHHCCC
DETEVRAAEHNLNYITLDGNIGCMVNGAGLAMATMDVIKLHGGAPANFLDVGGGTNAERV
HHHHHHHHHCCCCEEEECCCEEEEEECCCHHHHHHHHHHCCCCCCCCEEECCCCCCHHHH
AEAFKIILSSPSVEGILVNIFGGIVRCDMIAEGIVAAVQDVGVEVPVVVRLEGTNVEQGK
HHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHH
QILADSGLDLIPADDLADAAAKIVDIAGQVA
HHHHHCCCCCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNLHEFQAKHLFTEAGIAIPRGYVARSSAEARAAAERLGGSAWVVKAQVHAGGRGKAGGV
CCCHHHHHHHHHHHCCCCCCCCHHCCCCHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCE
RVIQEGDEIERYADSLLGERLVTHQTDGRGQPIHALLVEEGLEIARELYLGALVDRASQR
EEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCE
VVFMVSAAGGMDIEEVAASEPERIHTVRVHPAAGLQPYQCRQLGFALGLDKAQVGDLTRM
EEEEEECCCCCCHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHHH
MQGLYRLFLERDLSLVEINPLIVTGEGRLLALDAKVTVDDNAVEIGRQSQIQDMRDLTQE
HHHHHHHHHHCCCCEEEECEEEEECCCEEEEEEEEEEECCCHHHCCCHHHHHHHHHHCCC
DETEVRAAEHNLNYITLDGNIGCMVNGAGLAMATMDVIKLHGGAPANFLDVGGGTNAERV
HHHHHHHHHCCCCEEEECCCEEEEEECCCHHHHHHHHHHCCCCCCCCEEECCCCCCHHHH
AEAFKIILSSPSVEGILVNIFGGIVRCDMIAEGIVAAVQDVGVEVPVVVRLEGTNVEQGK
HHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHH
QILADSGLDLIPADDLADAAAKIVDIAGQVA
HHHHHCCCCCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA