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The map label for this gene is pilE [H]

Identifier: 121999021

GI number: 121999021

Start: 2456775

End: 2457230

Strand: Reverse

Name: pilE [H]

Synonym: Hhal_2242

Alternate gene names: 121999021

Gene position: 2457230-2456775 (Counterclockwise)

Preceding gene: 121999023

Following gene: 121999019

Centisome position: 91.74

GC content: 65.79

Gene sequence:

>456_bases
ATGAACACGTGTATCCGGCGGCGCTGGCGCTGCGCCGCCTTCACCCTGATCGAGCTGATGATCGTGGTGGCCATCATCGC
CATGCTGGCGGCCATCGCGGTCCCCCAGTACCAGAGCTACGTCGCTCGCACCCAGTTCACCGAGGCGTTGACCCTGTTCG
GTGGGGTGCGCACCGCCGTGGAGTCCGAGGTCCACCTCCGCGGCGCCGAAGGGGTCAATTCGGATTGGATCGAGGAGCAG
GTGGGGGACGGCGGTGACTACATCAACGACATCGAGGTGCAGACCAATGCTGGCGACGTCGAGGTGCAGATGACCTTCGC
GACTCAGGGGGTCAACGCTGAACTGGCCGGTCAGAGCGTGACCTTTACGGGCGCGGAATGGGACGAGGGCGGGGCGTGGT
CGTGTGATCTCCCCGACGACCTGGCGCATGTGGCCACCGGCCTGTGCGCCGAATGA

Upstream 100 bases:

>100_bases
CTTGATGACCATCAGCCCGGGCCTCCGCGACCCGCCGCGGGCGTAGCCGGAGCACAGTGTCACAAGTCATTCCGTTTCGG
GTCTCACAGGGAGGTGAGCC

Downstream 100 bases:

>100_bases
TCGGCTCCAACTGAGCCGAGCCGGCTCCTCCTGTACGGGGTCGCGCTTGGTGGGGTGTGCCGGGGGCTCTGGGACGCCCC
GGCGCGCCTTTCTACCGGGG

Product: fimbrial protein pilin

Products: NA

Alternate protein names: Pilin [H]

Number of amino acids: Translated: 151; Mature: 151

Protein sequence:

>151_residues
MNTCIRRRWRCAAFTLIELMIVVAIIAMLAAIAVPQYQSYVARTQFTEALTLFGGVRTAVESEVHLRGAEGVNSDWIEEQ
VGDGGDYINDIEVQTNAGDVEVQMTFATQGVNAELAGQSVTFTGAEWDEGGAWSCDLPDDLAHVATGLCAE

Sequences:

>Translated_151_residues
MNTCIRRRWRCAAFTLIELMIVVAIIAMLAAIAVPQYQSYVARTQFTEALTLFGGVRTAVESEVHLRGAEGVNSDWIEEQ
VGDGGDYINDIEVQTNAGDVEVQMTFATQGVNAELAGQSVTFTGAEWDEGGAWSCDLPDDLAHVATGLCAE
>Mature_151_residues
MNTCIRRRWRCAAFTLIELMIVVAIIAMLAAIAVPQYQSYVARTQFTEALTLFGGVRTAVESEVHLRGAEGVNSDWIEEQ
VGDGGDYINDIEVQTNAGDVEVQMTFATQGVNAELAGQSVTFTGAEWDEGGAWSCDLPDDLAHVATGLCAE

Specific function: This protein is the predominant Neisseria surface antigen, which allows adhesion of the bacterium to various host cells [H]

COG id: COG4969

COG function: function code NU; Tfp pilus assembly protein, major pilin PilA

Gene ontology:

Cell location: Fimbrium [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N-Me-Phe pilin family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001082
- InterPro:   IPR012902
- InterPro:   IPR001120 [H]

Pfam domain/function: PF07963 N_methyl; PF00114 Pilin [H]

EC number: NA

Molecular weight: Translated: 16303; Mature: 16303

Theoretical pI: Translated: 3.88; Mature: 3.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTCIRRRWRCAAFTLIELMIVVAIIAMLAAIAVPQYQSYVARTQFTEALTLFGGVRTAV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
ESEVHLRGAEGVNSDWIEEQVGDGGDYINDIEVQTNAGDVEVQMTFATQGVNAELAGQSV
HHHHEECCCCCCCHHHHHHHHCCCCCCCCEEEEEECCCCEEEEEEEEECCCCCEECCCEE
TFTGAEWDEGGAWSCDLPDDLAHVATGLCAE
EEECCCCCCCCEEECCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MNTCIRRRWRCAAFTLIELMIVVAIIAMLAAIAVPQYQSYVARTQFTEALTLFGGVRTAV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
ESEVHLRGAEGVNSDWIEEQVGDGGDYINDIEVQTNAGDVEVQMTFATQGVNAELAGQSV
HHHHEECCCCCCCHHHHHHHHCCCCCCCCEEEEEECCCCEEEEEEEEECCCCCEECCCEE
TFTGAEWDEGGAWSCDLPDDLAHVATGLCAE
EEECCCCCCCCEEECCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919; 9515697 [H]