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The map label for this gene is dsbC [H]

Identifier: 121998723

GI number: 121998723

Start: 2141623

End: 2142186

Strand: Reverse

Name: dsbC [H]

Synonym: Hhal_1944

Alternate gene names: 121998723

Gene position: 2142186-2141623 (Counterclockwise)

Preceding gene: 121998724

Following gene: 121998722

Centisome position: 79.98

GC content: 70.21

Gene sequence:

>564_bases
ATGCGCAGGGAGTCGACGAGCGCCCGCGCGCCGCGCATTCGGACGGCACGCCGTGCCGCCCGGGTGCTGGTGTTCGGGGG
ATGCATGGGCGCGGCCACCGCGTCGGTGGGCATGATGCCGGAAGAGATCGCCGAGACCCTTGAGGCGATGCCCGAGGAGG
ATCTGATCGTCTACGAACCCGAGGAGGGGGAAGCGGAGCACAGCGTGACGGTCTTCACCGATGTGACCTGTCCCCACTGC
CAGGATCTCCACGCCGAGCTCGACGCGTACCTGGAACAGGGGATCCGGGTGCGGTATGCCGCCTTCGCCCTGTCCGATGC
CTCCCGGGCGTTGATGGACCAGGTCTGGTGCAGCGACGACCGGCACGAGGCCCTGGAGGCGGCGAAGTCCGGTGAAGAGC
CCGAGGCCGGGGCGTGCGACGCGTCACCGGTCGAGGACCACCAGGAGGTGGCGCAGCAGATCGGGGTGCCGGGTACGCCG
ACCATGGCCACCCCCGGGGGCGAGCTCTCCTTCCGGCTGACGCCGGAGGATCTGGCCGATCTGCTGGAGCAGGAGGCGCA
CTAG

Upstream 100 bases:

>100_bases
GGGCCTCGCGGGAGTTCCGGGCCCGGGAGGCGGATTACGCCCCCGGCTGGTACGCCTCGATCACCCGCGACATCTTCGGC
TAAGGGAAGAGGAGGGCGTG

Downstream 100 bases:

>100_bases
GGCGGTTCGGGCCGCAGGAGGGATGACCATGACAGCACGGAAGGGGGAGCGAGGCCGGCTTGGTGGTGTGGCCGCTGGCC
TGCTGGCACTCAGTGGCGCG

Product: protein-disulfide isomerase-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
MRRESTSARAPRIRTARRAARVLVFGGCMGAATASVGMMPEEIAETLEAMPEEDLIVYEPEEGEAEHSVTVFTDVTCPHC
QDLHAELDAYLEQGIRVRYAAFALSDASRALMDQVWCSDDRHEALEAAKSGEEPEAGACDASPVEDHQEVAQQIGVPGTP
TMATPGGELSFRLTPEDLADLLEQEAH

Sequences:

>Translated_187_residues
MRRESTSARAPRIRTARRAARVLVFGGCMGAATASVGMMPEEIAETLEAMPEEDLIVYEPEEGEAEHSVTVFTDVTCPHC
QDLHAELDAYLEQGIRVRYAAFALSDASRALMDQVWCSDDRHEALEAAKSGEEPEAGACDASPVEDHQEVAQQIGVPGTP
TMATPGGELSFRLTPEDLADLLEQEAH
>Mature_187_residues
MRRESTSARAPRIRTARRAARVLVFGGCMGAATASVGMMPEEIAETLEAMPEEDLIVYEPEEGEAEHSVTVFTDVTCPHC
QDLHAELDAYLEQGIRVRYAAFALSDASRALMDQVWCSDDRHEALEAAKSGEEPEAGACDASPVEDHQEVAQQIGVPGTP
TMATPGGELSFRLTPEDLADLLEQEAH

Specific function: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process. DsbC is reoxidized by a yet uncharacterized protein. Also acts as a disulfide isomerase [H]

COG id: COG1651

COG function: function code O; Protein-disulfide isomerase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1789260, Length=143, Percent_Identity=34.2657342657343, Blast_Score=92, Evalue=2e-20,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018950
- InterPro:   IPR009094
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10411 DsbC_N [H]

EC number: 5.3.4.1

Molecular weight: Translated: 20270; Mature: 20270

Theoretical pI: Translated: 4.12; Mature: 4.12

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRESTSARAPRIRTARRAARVLVFGGCMGAATASVGMMPEEIAETLEAMPEEDLIVYEP
CCCCCCCCCCCHHHHHHHHHHHHEECCCHHHHHHHHCCCHHHHHHHHHHCCCCCEEEECC
EEGEAEHSVTVFTDVTCPHCQDLHAELDAYLEQGIRVRYAAFALSDASRALMDQVWCSDD
CCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCC
RHEALEAAKSGEEPEAGACDASPVEDHQEVAQQIGVPGTPTMATPGGELSFRLTPEDLAD
HHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEECHHHHHH
LLEQEAH
HHHHCCC
>Mature Secondary Structure
MRRESTSARAPRIRTARRAARVLVFGGCMGAATASVGMMPEEIAETLEAMPEEDLIVYEP
CCCCCCCCCCCHHHHHHHHHHHHEECCCHHHHHHHHCCCHHHHHHHHHHCCCCCEEEECC
EEGEAEHSVTVFTDVTCPHCQDLHAELDAYLEQGIRVRYAAFALSDASRALMDQVWCSDD
CCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCC
RHEALEAAKSGEEPEAGACDASPVEDHQEVAQQIGVPGTPTMATPGGELSFRLTPEDLAD
HHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEECHHHHHH
LLEQEAH
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]