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The map label for this gene is bhuA [H]

Identifier: 121998685

GI number: 121998685

Start: 2099951

End: 2102032

Strand: Reverse

Name: bhuA [H]

Synonym: Hhal_1906

Alternate gene names: 121998685

Gene position: 2102032-2099951 (Counterclockwise)

Preceding gene: 121998686

Following gene: 121998678

Centisome position: 78.48

GC content: 71.61

Gene sequence:

>2082_bases
ATGAACACCCATGAACCAACGGCTGTGCGCCTGTTAGGCGCCCTGCTGGCTGCGGCGGTCTCGGTACCGGCCGGGGCCGC
GGAGGAGGGCGATGAGCACGCGTCCTCCACCAGCCTCTCGCCGGTGCGCATCGAGGCCGGCGGCGATCCCCTGGGCCGCG
GCGTGGCCAGCGAAGCCCTGCAGCGCCGCCAGGCCTCGAGCAGCGCCGAGATCTTCCGCGGCGAGGCCTCGGCCGGGGTC
GGCGGTGGCAGCCGCAACGCGCAGCGGCTCTACCTGCGCGGTGTCGAGTCCAACAACCTCAACGTCACCGTGGACGGGGC
CCGCCAGGGGCGGGACCTCCACCAGCACCGCGGCGGCCTCACCGGTCTGGACCCGGATCTGCTGCGGGCGGCCGATCTCG
ACCCGCGTCCGGCGGCGGACCAGGGCCCCGGTGCGCTGGGCGGTTCGGTGCGCTTCGAGACGGTGGACGCCCAGGATCTG
CTCGACCCCGACGAAGAGACTGGGGCCCGCCTGCGCGCCGGCTACGCCAGCGCCGACGAGGCCGAGCGCGGCTCGGCCAC
CGCCTTCGGCCGGCTGGGCGGCGACTGGGGCGCCCTGGCCCATATCGGTGCGGTCAACCGGGACGACTACCGGGTCGGCG
GCGGCGACACCATGCCGTACTCCGGCGGGCGCGATCGCGACTACCTGGCGCGCATCAGCCGCGTGCCGGCATCGGGCCAT
CAGCTGCGTCTCGGCGTGCAGCGCAACACCTTCGAGGGGGATCACCATTACGGCTCCTGGGGCAGTGACTTCGGTGATCC
GAGCGAGACGACACGCCAAGACCCGGTGGGCCAGGAGCAGCGCCGCGACACCTGGACCGCCGAGCACCGCTACCGCCCGG
CCGACCCCCACGTGGACTGGCAGGCCCGGGTCTACCGCAACGACAACCGCCTGGAACGCCAGGACGACAACACCACCACC
CGCGCCGTCGAGCAAGGCGGCGACCTGCGCAACACCTTCACCCTGGACGCCGGGCCGACCCGTCACCGGCTCACCGCCGG
TTTCGACTACTACACCGAGGACGGGCGCAGCGACCCCCACGGAGGCGGCTCGAGGCTCAGTCACCAGTCGCGCAACTTCG
GCGCCTTCGTGCAGAACCGCATGGCCTGGGAGCGGTTGCGCCTCTCCGCCGGGCTGCGTTACGACGACTATGTCACCGAC
CTGCAGGAGGAGACCCTCCAAGGCGATGCCGTCTCGCCCAACTTCAGTGCGGAGTACGACCTGACTGCCGGGTGGACCGC
CTTCGCCGGCTACGGCGAGGCGGTCAGTGGCGCCGGGATCCTGCCGATCGGCTGGCTGGCCTACATCGACGACGAAGAGA
CCAATCTGAATGACGGCGAGCCGTTCGAGGCCGAGGAGTCCCGCCGGCGCGAGGGCGGCCTGCGCTACCAGGGGCGGGAT
CTGATCACGGCCCGGGACCGCTTCGACTTCGAGGCGACGCTCTTCGAGACGCGGATCAAAAACAGTGTTGAGCGGGATGA
CCCGTGGGGCACACCGCACCAGCACAACCTGCCGCCCGATAGGCGACATGACGCGTTCTGGGATGAGGACGCCCCGCTGG
TTGGGGGCGTCCGCAACCGCCCCGATCCGGTCCGCCTGCGCGGCTACGAACTGCGCGCCGCCTGGGGCGTGGGCCCCTAC
GACGCCCGGCTTTCGTTCCTCAGCGCCGAGGCCGTGGACGACGACGGCGACCCGGTGGGGGTGATCCGGCGCCTGGGTGG
GGGCGGCGGTGACCGTCTGGTCTTCGATCAGCGCTGGGCGGCCCACGAGACCCTGACCCTGGGCTACACGCTCACCTGGG
TGGGGGATCACACCGACGTCCCCGACGACGAGCCGGAGCGCGACGGCTACCAACTCCACGACGTGCAGGCCGAGTGGCAG
CCGTGGGCCGACGACCGCCTGACCCTGGCGCTGGCGGTGAACAACCTCTTCGACGAGCAGTACGCCGAGCACACCTCCCT
GGCGGTGGAGGAGAACGACGAGTGGCAGATTCGCGACGAGCCCGGCCGGGACGTTCGGGTGACCGGCACCCTGCGCTTTT
GA

Upstream 100 bases:

>100_bases
ACAGTCGGTCTGACCCGCCTTCTGGCGCGGCGGCGTTTCGTCGTCGGGCCTCCCCCAGCAGAAGTCGCCAGCGCCCGTCG
CAAGACGAGGAGCGCTGACC

Downstream 100 bases:

>100_bases
GCCGGGTGCCGGGCTAGCCGCCGGCGGGCGGGTTGCCCAGGGCCGCCTCGAGGAGGTCGGCAATCCGCCCGTCCAGCCAG
TAGCCCGGGCGTCCGGGCTG

Product: TonB-dependent receptor

Products: NA

Alternate protein names: Brucella heme uptake protein A [H]

Number of amino acids: Translated: 693; Mature: 693

Protein sequence:

>693_residues
MNTHEPTAVRLLGALLAAAVSVPAGAAEEGDEHASSTSLSPVRIEAGGDPLGRGVASEALQRRQASSSAEIFRGEASAGV
GGGSRNAQRLYLRGVESNNLNVTVDGARQGRDLHQHRGGLTGLDPDLLRAADLDPRPAADQGPGALGGSVRFETVDAQDL
LDPDEETGARLRAGYASADEAERGSATAFGRLGGDWGALAHIGAVNRDDYRVGGGDTMPYSGGRDRDYLARISRVPASGH
QLRLGVQRNTFEGDHHYGSWGSDFGDPSETTRQDPVGQEQRRDTWTAEHRYRPADPHVDWQARVYRNDNRLERQDDNTTT
RAVEQGGDLRNTFTLDAGPTRHRLTAGFDYYTEDGRSDPHGGGSRLSHQSRNFGAFVQNRMAWERLRLSAGLRYDDYVTD
LQEETLQGDAVSPNFSAEYDLTAGWTAFAGYGEAVSGAGILPIGWLAYIDDEETNLNDGEPFEAEESRRREGGLRYQGRD
LITARDRFDFEATLFETRIKNSVERDDPWGTPHQHNLPPDRRHDAFWDEDAPLVGGVRNRPDPVRLRGYELRAAWGVGPY
DARLSFLSAEAVDDDGDPVGVIRRLGGGGGDRLVFDQRWAAHETLTLGYTLTWVGDHTDVPDDEPERDGYQLHDVQAEWQ
PWADDRLTLALAVNNLFDEQYAEHTSLAVEENDEWQIRDEPGRDVRVTGTLRF

Sequences:

>Translated_693_residues
MNTHEPTAVRLLGALLAAAVSVPAGAAEEGDEHASSTSLSPVRIEAGGDPLGRGVASEALQRRQASSSAEIFRGEASAGV
GGGSRNAQRLYLRGVESNNLNVTVDGARQGRDLHQHRGGLTGLDPDLLRAADLDPRPAADQGPGALGGSVRFETVDAQDL
LDPDEETGARLRAGYASADEAERGSATAFGRLGGDWGALAHIGAVNRDDYRVGGGDTMPYSGGRDRDYLARISRVPASGH
QLRLGVQRNTFEGDHHYGSWGSDFGDPSETTRQDPVGQEQRRDTWTAEHRYRPADPHVDWQARVYRNDNRLERQDDNTTT
RAVEQGGDLRNTFTLDAGPTRHRLTAGFDYYTEDGRSDPHGGGSRLSHQSRNFGAFVQNRMAWERLRLSAGLRYDDYVTD
LQEETLQGDAVSPNFSAEYDLTAGWTAFAGYGEAVSGAGILPIGWLAYIDDEETNLNDGEPFEAEESRRREGGLRYQGRD
LITARDRFDFEATLFETRIKNSVERDDPWGTPHQHNLPPDRRHDAFWDEDAPLVGGVRNRPDPVRLRGYELRAAWGVGPY
DARLSFLSAEAVDDDGDPVGVIRRLGGGGGDRLVFDQRWAAHETLTLGYTLTWVGDHTDVPDDEPERDGYQLHDVQAEWQ
PWADDRLTLALAVNNLFDEQYAEHTSLAVEENDEWQIRDEPGRDVRVTGTLRF
>Mature_693_residues
MNTHEPTAVRLLGALLAAAVSVPAGAAEEGDEHASSTSLSPVRIEAGGDPLGRGVASEALQRRQASSSAEIFRGEASAGV
GGGSRNAQRLYLRGVESNNLNVTVDGARQGRDLHQHRGGLTGLDPDLLRAADLDPRPAADQGPGALGGSVRFETVDAQDL
LDPDEETGARLRAGYASADEAERGSATAFGRLGGDWGALAHIGAVNRDDYRVGGGDTMPYSGGRDRDYLARISRVPASGH
QLRLGVQRNTFEGDHHYGSWGSDFGDPSETTRQDPVGQEQRRDTWTAEHRYRPADPHVDWQARVYRNDNRLERQDDNTTT
RAVEQGGDLRNTFTLDAGPTRHRLTAGFDYYTEDGRSDPHGGGSRLSHQSRNFGAFVQNRMAWERLRLSAGLRYDDYVTD
LQEETLQGDAVSPNFSAEYDLTAGWTAFAGYGEAVSGAGILPIGWLAYIDDEETNLNDGEPFEAEESRRREGGLRYQGRD
LITARDRFDFEATLFETRIKNSVERDDPWGTPHQHNLPPDRRHDAFWDEDAPLVGGVRNRPDPVRLRGYELRAAWGVGPY
DARLSFLSAEAVDDDGDPVGVIRRLGGGGGDRLVFDQRWAAHETLTLGYTLTWVGDHTDVPDDEPERDGYQLHDVQAEWQ
PWADDRLTLALAVNNLFDEQYAEHTSLAVEENDEWQIRDEPGRDVRVTGTLRF

Specific function: Heme transporter playing an important role in stationary-phase iron acquisition and required for maintenance of chronic infection in mice [H]

COG id: COG1629

COG function: function code P; Outer membrane receptor proteins, mostly Fe transport

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 76365; Mature: 76365

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: PS01156 TONB_DEPENDENT_REC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
0.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTHEPTAVRLLGALLAAAVSVPAGAAEEGDEHASSTSLSPVRIEAGGDPLGRGVASEAL
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCCCCCEEEEECCCCHHHHHHHHHHH
QRRQASSSAEIFRGEASAGVGGGSRNAQRLYLRGVESNNLNVTVDGARQGRDLHQHRGGL
HHHHCCCCHHHEECCCCCCCCCCCCCCEEEEEEECCCCCCEEEECCCCCCCHHHHHCCCC
TGLDPDLLRAADLDPRPAADQGPGALGGSVRFETVDAQDLLDPDEETGARLRAGYASADE
CCCCHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECHHHCCCCCHHHCCCEECCCCCCCC
AERGSATAFGRLGGDWGALAHIGAVNRDDYRVGGGDTMPYSGGRDRDYLARISRVPASGH
CCCCCCEEECCCCCCHHHHHHHCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHCCCCCC
QLRLGVQRNTFEGDHHYGSWGSDFGDPSETTRQDPVGQEQRRDTWTAEHRYRPADPHVDW
EEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCHHCCCCCCCCCCCC
QARVYRNDNRLERQDDNTTTRAVEQGGDLRNTFTLDAGPTRHRLTAGFDYYTEDGRSDPH
EEEEEECCCCCCCCCCCHHHHHHHCCCCCCEEEEECCCCCCCEEEECCCCCCCCCCCCCC
GGGSRLSHQSRNFGAFVQNRMAWERLRLSAGLRYDDYVTDLQEETLQGDAVSPNFSAEYD
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEE
LTAGWTAFAGYGEAVSGAGILPIGWLAYIDDEETNLNDGEPFEAEESRRREGGLRYQGRD
CCCCCHHHCCCCCHHCCCCCCEEEEEEEECCCCCCCCCCCCCCCHHHHHHHCCCEECCCE
LITARDRFDFEATLFETRIKNSVERDDPWGTPHQHNLPPDRRHDAFWDEDAPLVGGVRNR
EEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PDPVRLRGYELRAAWGVGPYDARLSFLSAEAVDDDGDPVGVIRRLGGGGGDRLVFDQRWA
CCCEEEEEEEEEEECCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCEEEECCCCC
AHETLTLGYTLTWVGDHTDVPDDEPERDGYQLHDVQAEWQPWADDRLTLALAVNNLFDEQ
CCCEEEEEEEEEEECCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCEEEEEEHHHHHHHH
YAEHTSLAVEENDEWQIRDEPGRDVRVTGTLRF
HHHHHEEEEECCCCEEEECCCCCEEEEEEEECC
>Mature Secondary Structure
MNTHEPTAVRLLGALLAAAVSVPAGAAEEGDEHASSTSLSPVRIEAGGDPLGRGVASEAL
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCCCCCEEEEECCCCHHHHHHHHHHH
QRRQASSSAEIFRGEASAGVGGGSRNAQRLYLRGVESNNLNVTVDGARQGRDLHQHRGGL
HHHHCCCCHHHEECCCCCCCCCCCCCCEEEEEEECCCCCCEEEECCCCCCCHHHHHCCCC
TGLDPDLLRAADLDPRPAADQGPGALGGSVRFETVDAQDLLDPDEETGARLRAGYASADE
CCCCHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECHHHCCCCCHHHCCCEECCCCCCCC
AERGSATAFGRLGGDWGALAHIGAVNRDDYRVGGGDTMPYSGGRDRDYLARISRVPASGH
CCCCCCEEECCCCCCHHHHHHHCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHCCCCCC
QLRLGVQRNTFEGDHHYGSWGSDFGDPSETTRQDPVGQEQRRDTWTAEHRYRPADPHVDW
EEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCHHCCCCCCCCCCCC
QARVYRNDNRLERQDDNTTTRAVEQGGDLRNTFTLDAGPTRHRLTAGFDYYTEDGRSDPH
EEEEEECCCCCCCCCCCHHHHHHHCCCCCCEEEEECCCCCCCEEEECCCCCCCCCCCCCC
GGGSRLSHQSRNFGAFVQNRMAWERLRLSAGLRYDDYVTDLQEETLQGDAVSPNFSAEYD
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEE
LTAGWTAFAGYGEAVSGAGILPIGWLAYIDDEETNLNDGEPFEAEESRRREGGLRYQGRD
CCCCCHHHCCCCCHHCCCCCCEEEEEEEECCCCCCCCCCCCCCCHHHHHHHCCCEECCCE
LITARDRFDFEATLFETRIKNSVERDDPWGTPHQHNLPPDRRHDAFWDEDAPLVGGVRNR
EEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PDPVRLRGYELRAAWGVGPYDARLSFLSAEAVDDDGDPVGVIRRLGGGGGDRLVFDQRWA
CCCEEEEEEEEEEECCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCEEEECCCCC
AHETLTLGYTLTWVGDHTDVPDDEPERDGYQLHDVQAEWQPWADDRLTLALAVNNLFDEQ
CCCEEEEEEEEEEECCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCEEEEEEHHHHHHHH
YAEHTSLAVEENDEWQIRDEPGRDVRVTGTLRF
HHHHHEEEEECCCCEEEECCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA