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The map label for this gene is ispH [H]

Identifier: 121998613

GI number: 121998613

Start: 2004897

End: 2005853

Strand: Reverse

Name: ispH [H]

Synonym: Hhal_1834

Alternate gene names: 121998613

Gene position: 2005853-2004897 (Counterclockwise)

Preceding gene: 121998614

Following gene: 121998611

Centisome position: 74.89

GC content: 68.13

Gene sequence:

>957_bases
GTGCCCAAGATCCACCTTGCCAACCCTCGCGGTTTCTGTGCCGGCGTGGACCGCGCCATTGCCATTGTCGATCGAGCCCT
GGCGGTCTACGGGTCTCCGGTCTATGTCCGTCACGAGGTGGTCCACAATCGCTTTGTGGTGGATGACCTGCGCGGGCGGG
GTGCGGTCTTCGTCGAGGAGCTGCACGAGGTGCCCGACGGGGCCACCGTCATCTTCAGCGCCCACGGCGTGCCGCAATGG
GTCGCCGACGAGGCCGAGCGCCGCGGGCTGCAGGTCTTTGATGCCACCTGCCCGCTGGTGACCAAGGTCCACAAGGAGGT
GCGCGGGCATGCCCGCGCCGGTCGCGAAGTGGTGCTGATCGGTCACGCCGGCCACCCGGAGGTGGAGGGCACCATGGGCC
AGTATCTGGCCCCTGAGGGGCAGGGCGGCATCTATCTGGTGCAGAACCAGGAGGAGGCGGCGGCACTGCAGGTCCGGCGT
CCGGACGATCTCGCCTTCGTTACCCAGACCACGCTGTCGGTGGACGATGCCGCCGGTATCGTTGAGGCGCTGCAGCGGCG
TTTTCCTGCCATCCAGGGGCCGCGTAAGGACGATATCTGCTACGCCACGCAGAATCGCCAGGATGCCGTGCGCGCCCTGG
CCGAAGAAGTGGACTTGATGCTGGTGGTGGGATCGGTCAACAGCTCCAATTCCAACCGCCTGCGTGAACTCGCCGTGCGC
TGCGGCACCGAGGCGTATCTGATCGACGGCGCCGCCGATCTGGACCGCGACTGGCTCGACGGCCGGCAGGCGATCGGTGT
GACGGCGGGGGCCTCGGCGCCGGAGAGCACGGTCATCGAGGTGGTCGAGCAGCTCCGCGCCTGGGGGTGCGAGCCGCCGG
AGGAGCGCTCGGGGAAGGCAGAGACGGTGACCTTCGGGTTGCCCAAGGAGCTCGGGCAACCACCGGCAACGTCATGA

Upstream 100 bases:

>100_bases
GTCGCCGATATCGCCATCACGGTCGGTGCAGGGCTCGTGATCGTGATCCTTCTCTTTTTTGATCGGTCGAACCTGTAGGG
AAGAGCGAACGGAGGTCCCC

Downstream 100 bases:

>100_bases
GCGTCGCGCCGGTGCGTCGTCCCGCTCCTTGAGGGGGTGGAGGACCAGAAGGGCCGCGGGCCGGCGTTGACGGACCTGCT
CGGCGACCGCCCGCGGTACG

Product: hydroxymethylbutenyl pyrophosphate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 318; Mature: 317

Protein sequence:

>318_residues
MPKIHLANPRGFCAGVDRAIAIVDRALAVYGSPVYVRHEVVHNRFVVDDLRGRGAVFVEELHEVPDGATVIFSAHGVPQW
VADEAERRGLQVFDATCPLVTKVHKEVRGHARAGREVVLIGHAGHPEVEGTMGQYLAPEGQGGIYLVQNQEEAAALQVRR
PDDLAFVTQTTLSVDDAAGIVEALQRRFPAIQGPRKDDICYATQNRQDAVRALAEEVDLMLVVGSVNSSNSNRLRELAVR
CGTEAYLIDGAADLDRDWLDGRQAIGVTAGASAPESTVIEVVEQLRAWGCEPPEERSGKAETVTFGLPKELGQPPATS

Sequences:

>Translated_318_residues
MPKIHLANPRGFCAGVDRAIAIVDRALAVYGSPVYVRHEVVHNRFVVDDLRGRGAVFVEELHEVPDGATVIFSAHGVPQW
VADEAERRGLQVFDATCPLVTKVHKEVRGHARAGREVVLIGHAGHPEVEGTMGQYLAPEGQGGIYLVQNQEEAAALQVRR
PDDLAFVTQTTLSVDDAAGIVEALQRRFPAIQGPRKDDICYATQNRQDAVRALAEEVDLMLVVGSVNSSNSNRLRELAVR
CGTEAYLIDGAADLDRDWLDGRQAIGVTAGASAPESTVIEVVEQLRAWGCEPPEERSGKAETVTFGLPKELGQPPATS
>Mature_317_residues
PKIHLANPRGFCAGVDRAIAIVDRALAVYGSPVYVRHEVVHNRFVVDDLRGRGAVFVEELHEVPDGATVIFSAHGVPQWV
ADEAERRGLQVFDATCPLVTKVHKEVRGHARAGREVVLIGHAGHPEVEGTMGQYLAPEGQGGIYLVQNQEEAAALQVRRP
DDLAFVTQTTLSVDDAAGIVEALQRRFPAIQGPRKDDICYATQNRQDAVRALAEEVDLMLVVGSVNSSNSNRLRELAVRC
GTEAYLIDGAADLDRDWLDGRQAIGVTAGASAPESTVIEVVEQLRAWGCEPPEERSGKAETVTFGLPKELGQPPATS

Specific function: Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) [H]

COG id: COG0761

COG function: function code IM; Penicillin tolerance protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ispH family [H]

Homologues:

Organism=Escherichia coli, GI1786212, Length=309, Percent_Identity=61.8122977346278, Blast_Score=387, Evalue=1e-109,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003451 [H]

Pfam domain/function: PF02401 LYTB [H]

EC number: =1.17.1.2 [H]

Molecular weight: Translated: 34378; Mature: 34247

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKIHLANPRGFCAGVDRAIAIVDRALAVYGSPVYVRHEVVHNRFVVDDLRGRGAVFVEE
CCCEEECCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHCEEEEECCCCCCHHHHHH
LHEVPDGATVIFSAHGVPQWVADEAERRGLQVFDATCPLVTKVHKEVRGHARAGREVVLI
HHHCCCCCEEEEECCCCCHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHCCCEEEEE
GHAGHPEVEGTMGQYLAPEGQGGIYLVQNQEEAAALQVRRPDDLAFVTQTTLSVDDAAGI
ECCCCCCCCCCCHHHCCCCCCCCEEEEECCCCCEEEEEECCCCEEEEEEEECCCHHHHHH
VEALQRRFPAIQGPRKDDICYATQNRQDAVRALAEEVDLMLVVGSVNSSNSNRLRELAVR
HHHHHHHCCCCCCCCCCCCEEECCCHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHH
CGTEAYLIDGAADLDRDWLDGRQAIGVTAGASAPESTVIEVVEQLRAWGCEPPEERSGKA
CCCEEEEECCCCCCCHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHCCCC
ETVTFGLPKELGQPPATS
EEEEECCHHHHCCCCCCC
>Mature Secondary Structure 
PKIHLANPRGFCAGVDRAIAIVDRALAVYGSPVYVRHEVVHNRFVVDDLRGRGAVFVEE
CCEEECCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHCEEEEECCCCCCHHHHHH
LHEVPDGATVIFSAHGVPQWVADEAERRGLQVFDATCPLVTKVHKEVRGHARAGREVVLI
HHHCCCCCEEEEECCCCCHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHCCCEEEEE
GHAGHPEVEGTMGQYLAPEGQGGIYLVQNQEEAAALQVRRPDDLAFVTQTTLSVDDAAGI
ECCCCCCCCCCCHHHCCCCCCCCEEEEECCCCCEEEEEECCCCEEEEEEEECCCHHHHHH
VEALQRRFPAIQGPRKDDICYATQNRQDAVRALAEEVDLMLVVGSVNSSNSNRLRELAVR
HHHHHHHCCCCCCCCCCCCEEECCCHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHH
CGTEAYLIDGAADLDRDWLDGRQAIGVTAGASAPESTVIEVVEQLRAWGCEPPEERSGKA
CCCEEEEECCCCCCCHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHCCCC
ETVTFGLPKELGQPPATS
EEEEECCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA