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The map label for this gene is hcaT [H]

Identifier: 121998592

GI number: 121998592

Start: 1986390

End: 1987559

Strand: Reverse

Name: hcaT [H]

Synonym: Hhal_1813

Alternate gene names: 121998592

Gene position: 1987559-1986390 (Counterclockwise)

Preceding gene: 121998593

Following gene: 121998591

Centisome position: 74.21

GC content: 68.46

Gene sequence:

>1170_bases
TTGAGCGGCGGGACTCCGGGCGGGGCGCAACCGGCGTTGCCGTACTGGCGGCTCTCGGGCTTCTACCTCTTCTTCTTTGC
CGCCCTCGGGGCCCTGATGCCCTACTGGGGGCCGTACCTGCGCGCCGAGGGCTTCTCCTCGGCGGAGATCGGTCAACTGC
TGGCCATTCTCCACGCCACCAAGATCATCGCCCCGAACGTCTGGGGGGTGCTGGCCGACCGCCTTAATCGACGCATGGCG
GTGGTGCGCGCGGCCTCGGTGGTGGCGCTCCTGGCCTTCTCGGCGATCCTCCTCGCCGAGACCTTCGGCGCGGTGGCGCT
GGTCATGGCCCTGTTCGGGTTCTTCTGGAACGCCGCACTGCCCCAGTACGAAGCCAATACGTTCAACCATCTGCGCGGGC
AGGAGCACCGCTACAGCCGCATCCGGCTGTGGGGGTCGGTGGGGTTCATCCTGTCGGTGATGGGCATCGGCGAGATGCTC
GATCGGGCCGGTTTCGATGCACTGCCCTACGTGGTGCTGCTGATCTTCGGCGGGCTCGCGGTTTCCAGCCTCATCGCGCC
GGAGGCCGGGCGTGCCACGCACCGCGCCGATGGGGACGGTTTCTGGGAGACCTTGCGCCGGCCGGCGGTGATCGGGTTCT
TTCTGGCCTGTTTCCTCAACCAGATGGGCCACGGACCGTTCTACGGCTTCTTCAGCATCTACCTGGAGGATCACGGCTAC
AGCGGCGGGCTGATCGGCGCGCTGTGGGCCTGGGGGGTGGTGGCTGAGATCGCCATCTTCCTGGTTATGCACCGGCTGCT
GCCTCGTTTTGGCGCCCGCACCTTGCTGACCCTGGCCCTAGCGCTGGGCGGCCTGCGCTGGCTGATGGTCGCCGCGTGGG
TGGATTCGGCCTGGCTCGTGGCCCTGAGCCAGACCTTCCATGCCGCCAGCTTCGGGATCTATCACGCGGTGGCGATCGAT
GTGGTCAACCGGTTCTTCACCGGCGCCGCGCAGGGTCGGGGGCAGGCGCTGTACTCCAGTCTGACCTTCGGTGCCGGGGT
GGCGCTGGGGTCGCTGCTCTCCGGCATGGCCTGGGATCTCTTCGGCGGGCAGACCTTCCTGGCTGCCAGCGCGGTGGCCT
TCCTGGCGGCGATCCTGGCGGCCTGGAGCCTGCGCGGGCAGCGGGCCTGA

Upstream 100 bases:

>100_bases
GCGCTGGTGGTGATGGACCACTGGCTGCGGCATCGGGCACAGAACGCCGATGTCGAGTCCGGGACCCCGGTGCTGCCCGC
CCGCGACCGGGAGTAATCCC

Downstream 100 bases:

>100_bases
GGGCATTTCCCCCGAGGGGGGTCGGTCCGATATAATGTTCAAGTGAATGTTTCTAAGCCAATTGATAGAACAGGCCAATG
ACCGGGAAGACCCTCTACGA

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 389; Mature: 388

Protein sequence:

>389_residues
MSGGTPGGAQPALPYWRLSGFYLFFFAALGALMPYWGPYLRAEGFSSAEIGQLLAILHATKIIAPNVWGVLADRLNRRMA
VVRAASVVALLAFSAILLAETFGAVALVMALFGFFWNAALPQYEANTFNHLRGQEHRYSRIRLWGSVGFILSVMGIGEML
DRAGFDALPYVVLLIFGGLAVSSLIAPEAGRATHRADGDGFWETLRRPAVIGFFLACFLNQMGHGPFYGFFSIYLEDHGY
SGGLIGALWAWGVVAEIAIFLVMHRLLPRFGARTLLTLALALGGLRWLMVAAWVDSAWLVALSQTFHAASFGIYHAVAID
VVNRFFTGAAQGRGQALYSSLTFGAGVALGSLLSGMAWDLFGGQTFLAASAVAFLAAILAAWSLRGQRA

Sequences:

>Translated_389_residues
MSGGTPGGAQPALPYWRLSGFYLFFFAALGALMPYWGPYLRAEGFSSAEIGQLLAILHATKIIAPNVWGVLADRLNRRMA
VVRAASVVALLAFSAILLAETFGAVALVMALFGFFWNAALPQYEANTFNHLRGQEHRYSRIRLWGSVGFILSVMGIGEML
DRAGFDALPYVVLLIFGGLAVSSLIAPEAGRATHRADGDGFWETLRRPAVIGFFLACFLNQMGHGPFYGFFSIYLEDHGY
SGGLIGALWAWGVVAEIAIFLVMHRLLPRFGARTLLTLALALGGLRWLMVAAWVDSAWLVALSQTFHAASFGIYHAVAID
VVNRFFTGAAQGRGQALYSSLTFGAGVALGSLLSGMAWDLFGGQTFLAASAVAFLAAILAAWSLRGQRA
>Mature_388_residues
SGGTPGGAQPALPYWRLSGFYLFFFAALGALMPYWGPYLRAEGFSSAEIGQLLAILHATKIIAPNVWGVLADRLNRRMAV
VRAASVVALLAFSAILLAETFGAVALVMALFGFFWNAALPQYEANTFNHLRGQEHRYSRIRLWGSVGFILSVMGIGEMLD
RAGFDALPYVVLLIFGGLAVSSLIAPEAGRATHRADGDGFWETLRRPAVIGFFLACFLNQMGHGPFYGFFSIYLEDHGYS
GGLIGALWAWGVVAEIAIFLVMHRLLPRFGARTLLTLALALGGLRWLMVAAWVDSAWLVALSQTFHAASFGIYHAVAIDV
VNRFFTGAAQGRGQALYSSLTFGAGVALGSLLSGMAWDLFGGQTFLAASAVAFLAAILAAWSLRGQRA

Specific function: Probable permease involved in the uptake of 3- phenylpropionic acid [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lacY/rafB permease family. HcaT subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788886, Length=381, Percent_Identity=28.8713910761155, Blast_Score=117, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022814
- InterPro:   IPR016196
- InterPro:   IPR005276 [H]

Pfam domain/function: PF01306 LacY_symp [H]

EC number: NA

Molecular weight: Translated: 41872; Mature: 41741

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGGTPGGAQPALPYWRLSGFYLFFFAALGALMPYWGPYLRAEGFSSAEIGQLLAILHAT
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHH
KIIAPNVWGVLADRLNRRMAVVRAASVVALLAFSAILLAETFGAVALVMALFGFFWNAAL
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PQYEANTFNHLRGQEHRYSRIRLWGSVGFILSVMGIGEMLDRAGFDALPYVVLLIFGGLA
CCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
VSSLIAPEAGRATHRADGDGFWETLRRPAVIGFFLACFLNQMGHGPFYGFFSIYLEDHGY
HHHHHCCCCCCCCCCCCCCHHHHHHHCHHHHHHHHHHHHHHHCCCCHHHHHHEEEECCCC
SGGLIGALWAWGVVAEIAIFLVMHRLLPRFGARTLLTLALALGGLRWLMVAAWVDSAWLV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALSQTFHAASFGIYHAVAIDVVNRFFTGAAQGRGQALYSSLTFGAGVALGSLLSGMAWDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGGQTFLAASAVAFLAAILAAWSLRGQRA
CCCHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SGGTPGGAQPALPYWRLSGFYLFFFAALGALMPYWGPYLRAEGFSSAEIGQLLAILHAT
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHH
KIIAPNVWGVLADRLNRRMAVVRAASVVALLAFSAILLAETFGAVALVMALFGFFWNAAL
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PQYEANTFNHLRGQEHRYSRIRLWGSVGFILSVMGIGEMLDRAGFDALPYVVLLIFGGLA
CCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
VSSLIAPEAGRATHRADGDGFWETLRRPAVIGFFLACFLNQMGHGPFYGFFSIYLEDHGY
HHHHHCCCCCCCCCCCCCCHHHHHHHCHHHHHHHHHHHHHHHCCCCHHHHHHEEEECCCC
SGGLIGALWAWGVVAEIAIFLVMHRLLPRFGARTLLTLALALGGLRWLMVAAWVDSAWLV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALSQTFHAASFGIYHAVAIDVVNRFFTGAAQGRGQALYSSLTFGAGVALGSLLSGMAWDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGGQTFLAASAVAFLAAILAAWSLRGQRA
CCCHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9603882; 9205837; 9278503 [H]