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The map label for this gene is aroC

Identifier: 121998593

GI number: 121998593

Start: 1987564

End: 1988667

Strand: Reverse

Name: aroC

Synonym: Hhal_1814

Alternate gene names: 121998593

Gene position: 1988667-1987564 (Counterclockwise)

Preceding gene: 121998600

Following gene: 121998592

Centisome position: 74.25

GC content: 70.29

Gene sequence:

>1104_bases
ATGTCTGGGAATACCTTTGGCACCCTGTTTACGGTCACCACCTTTGGTGAGAGTCACGGCCCCGCGCTGGGCGGCGTGGT
GGACGGCTGCCCGCCGGGGCTGGCCCTGACCGAGGCCGACCTGCAAGTCGAGCTCGATCGGCGTCGGCCCGGGCGCTCCA
AGCACACCACGCAGCGCCGCGAGAGCGATCAGGTGCAGATCCTCTCCGGGGTCTTCGAGGGGGTGACCACCGGCACCCCC
ATCGGTCTGCTCATCGAGAACACCGACCAGCGTTCCAAGGATTACTCCGAGATCGCCCAGCGGTTCCGGCCTGGGCACGC
CGACTACACCTATCAGCAGAAGTACGGGGTTCGCGATTACCGCGGCGGCGGCCGTTCTTCGGCTCGGGAGACCGCCGTGC
GGGTGGCCGCCGGGGCCATCGCCCGCCGCTACCTCGCCCAGCGTCTCGGTATCGAGATCCGCGGGCGGCTGGCCCAGATG
GGTGGGATCGAACTCGGCGCCGAGGACTGGTCGGCGGTGGATGACAACGACTTCTTCTGCGCCGACCCGGCGCGCATCCC
GGAGCTCGAGGCCCTGATCCAAGAGGTGCGTAAGGCTGGCGATTCGGTGGGCGCTGCCGTCGAGGTCGAGGTCCGCCATG
TGCCGCCGGGGCTCGGCGAGCCGGTCTTCGACCGTCTGGATGCCGACCTGGCCAAGGCGCTGATGTCCATCAACGCCGTC
AAGGGGGTGGAGGTCGGCGCCGGCATGGCGGCGGCAGGGCAGCGGGGCAGCGCCCATCGCGACGAGCTCACCCCCGCGGG
ATTCGCCGGCAACCAGTCCGGCGGGGTGCTCGGCGGGATCTCCAGCGGACAGGATCTGGTGGTGCGGGCGGCGCTGAAGC
CGACCTCGAGCATGCTCATCCCGGGGCGCTCGGTGGACGTGCACGGCGAGCCGGTCTCGGTGGTGACCAAGGGGCGCCAC
GATCCGTGTGTCGGTATCCGTGCGGTGCCCATCGCCGAGGCCATGGCGGCGCTGGTGGTGATGGACCACTGGCTGCGGCA
TCGGGCACAGAACGCCGATGTCGAGTCCGGGACCCCGGTGCTGCCCGCCCGCGACCGGGAGTAA

Upstream 100 bases:

>100_bases
GTTGGTGGGGGCGGGTGCGTGCATGGCGTGCAGGATACGCCCACCGGCCAGTCGCCGGCCAGGCCCGCCCACGGATCTGC
AGTGCTACAATCGACGGCCT

Downstream 100 bases:

>100_bases
TCCCTTGAGCGGCGGGACTCCGGGCGGGGCGCAACCGGCGTTGCCGTACTGGCGGCTCTCGGGCTTCTACCTCTTCTTCT
TTGCCGCCCTCGGGGCCCTG

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase

Number of amino acids: Translated: 367; Mature: 366

Protein sequence:

>367_residues
MSGNTFGTLFTVTTFGESHGPALGGVVDGCPPGLALTEADLQVELDRRRPGRSKHTTQRRESDQVQILSGVFEGVTTGTP
IGLLIENTDQRSKDYSEIAQRFRPGHADYTYQQKYGVRDYRGGGRSSARETAVRVAAGAIARRYLAQRLGIEIRGRLAQM
GGIELGAEDWSAVDDNDFFCADPARIPELEALIQEVRKAGDSVGAAVEVEVRHVPPGLGEPVFDRLDADLAKALMSINAV
KGVEVGAGMAAAGQRGSAHRDELTPAGFAGNQSGGVLGGISSGQDLVVRAALKPTSSMLIPGRSVDVHGEPVSVVTKGRH
DPCVGIRAVPIAEAMAALVVMDHWLRHRAQNADVESGTPVLPARDRE

Sequences:

>Translated_367_residues
MSGNTFGTLFTVTTFGESHGPALGGVVDGCPPGLALTEADLQVELDRRRPGRSKHTTQRRESDQVQILSGVFEGVTTGTP
IGLLIENTDQRSKDYSEIAQRFRPGHADYTYQQKYGVRDYRGGGRSSARETAVRVAAGAIARRYLAQRLGIEIRGRLAQM
GGIELGAEDWSAVDDNDFFCADPARIPELEALIQEVRKAGDSVGAAVEVEVRHVPPGLGEPVFDRLDADLAKALMSINAV
KGVEVGAGMAAAGQRGSAHRDELTPAGFAGNQSGGVLGGISSGQDLVVRAALKPTSSMLIPGRSVDVHGEPVSVVTKGRH
DPCVGIRAVPIAEAMAALVVMDHWLRHRAQNADVESGTPVLPARDRE
>Mature_366_residues
SGNTFGTLFTVTTFGESHGPALGGVVDGCPPGLALTEADLQVELDRRRPGRSKHTTQRRESDQVQILSGVFEGVTTGTPI
GLLIENTDQRSKDYSEIAQRFRPGHADYTYQQKYGVRDYRGGGRSSARETAVRVAAGAIARRYLAQRLGIEIRGRLAQMG
GIELGAEDWSAVDDNDFFCADPARIPELEALIQEVRKAGDSVGAAVEVEVRHVPPGLGEPVFDRLDADLAKALMSINAVK
GVEVGAGMAAAGQRGSAHRDELTPAGFAGNQSGGVLGGISSGQDLVVRAALKPTSSMLIPGRSVDVHGEPVSVVTKGRHD
PCVGIRAVPIAEAMAALVVMDHWLRHRAQNADVESGTPVLPARDRE

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family

Homologues:

Organism=Escherichia coli, GI1788669, Length=359, Percent_Identity=69.3593314763231, Blast_Score=490, Evalue=1e-140,
Organism=Saccharomyces cerevisiae, GI6321290, Length=368, Percent_Identity=43.2065217391304, Blast_Score=290, Evalue=2e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROC_HALHL (A1WY16)

Other databases:

- EMBL:   CP000544
- RefSeq:   YP_001003380.1
- ProteinModelPortal:   A1WY16
- SMR:   A1WY16
- STRING:   A1WY16
- GeneID:   4711045
- GenomeReviews:   CP000544_GR
- KEGG:   hha:Hhal_1814
- eggNOG:   COG0082
- HOGENOM:   HBG292336
- OMA:   SRFTTQR
- PhylomeDB:   A1WY16
- ProtClustDB:   PRK05382
- BioCyc:   HHAL349124:HHAL_1814-MONOMER
- HAMAP:   MF_00300_B
- InterPro:   IPR000453
- InterPro:   IPR020541
- PANTHER:   PTHR21085
- PIRSF:   PIRSF001456
- TIGRFAMs:   TIGR00033

Pfam domain/function: PF01264 Chorismate_synt; SSF103263 Chorismate_synth

EC number: =4.2.3.5

Molecular weight: Translated: 38943; Mature: 38812

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1; PS00788 CHORISMATE_SYNTHASE_2; PS00789 CHORISMATE_SYNTHASE_3; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGNTFGTLFTVTTFGESHGPALGGVVDGCPPGLALTEADLQVELDRRRPGRSKHTTQRR
CCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCEEECCCEEEEECCCCCCCCCHHHHHH
ESDQVQILSGVFEGVTTGTPIGLLIENTDQRSKDYSEIAQRFRPGHADYTYQQKYGVRDY
CCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCEEHHHCCCCCC
RGGGRSSARETAVRVAAGAIARRYLAQRLGIEIRGRLAQMGGIELGAEDWSAVDDNDFFC
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCEECCCCCCCCCCCCEEE
ADPARIPELEALIQEVRKAGDSVGAAVEVEVRHVPPGLGEPVFDRLDADLAKALMSINAV
CCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHH
KGVEVGAGMAAAGQRGSAHRDELTPAGFAGNQSGGVLGGISSGQDLVVRAALKPTSSMLI
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCEEEEEECCCCCCEEC
PGRSVDVHGEPVSVVTKGRHDPCVGIRAVPIAEAMAALVVMDHWLRHRAQNADVESGTPV
CCCCEECCCCCEEEEECCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
LPARDRE
CCCCCCC
>Mature Secondary Structure 
SGNTFGTLFTVTTFGESHGPALGGVVDGCPPGLALTEADLQVELDRRRPGRSKHTTQRR
CCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCEEECCCEEEEECCCCCCCCCHHHHHH
ESDQVQILSGVFEGVTTGTPIGLLIENTDQRSKDYSEIAQRFRPGHADYTYQQKYGVRDY
CCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCEEHHHCCCCCC
RGGGRSSARETAVRVAAGAIARRYLAQRLGIEIRGRLAQMGGIELGAEDWSAVDDNDFFC
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCEECCCCCCCCCCCCEEE
ADPARIPELEALIQEVRKAGDSVGAAVEVEVRHVPPGLGEPVFDRLDADLAKALMSINAV
CCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHH
KGVEVGAGMAAAGQRGSAHRDELTPAGFAGNQSGGVLGGISSGQDLVVRAALKPTSSMLI
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCEEEEEECCCCCCEEC
PGRSVDVHGEPVSVVTKGRHDPCVGIRAVPIAEAMAALVVMDHWLRHRAQNADVESGTPV
CCCCEECCCCCEEEEECCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
LPARDRE
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA