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The map label for this gene is yciR [C]

Identifier: 121998494

GI number: 121998494

Start: 1877432

End: 1879681

Strand: Reverse

Name: yciR [C]

Synonym: Hhal_1715

Alternate gene names: 121998494

Gene position: 1879681-1877432 (Counterclockwise)

Preceding gene: 121998495

Following gene: 121998493

Centisome position: 70.18

GC content: 65.38

Gene sequence:

>2250_bases
ATGGGCGAAGACGAGCGGAGAACCCTTTCACCCGAGGCCCTGCGGGAAGCGGCGCGTCGGCGTCTGGAGCGGAGGGTGAC
GGACGTCTCCGACTGGAGCCGTGCGGATACCCAGTCCCTGGTGGCGGAGCTGGAACTGCACCAGCAGGAGCTGAGGATCC
AGAACGAGGAGCTGCAGCAGGCTCGAGACCGACTGGAAACCGCCCTAGACCGCTACCACGACCTGTTCCAGCGGGCTCCG
GTGGGTTATCTCCTGCTGGACGACGAGGGCCGGATCTGGGAGGCCAATCGGGCGGCCGCGGATCTCCTGGCCCCGGGGGG
CGATCTGACGGGCCAGCTCCTCTCTGATTTCGTGGCGGTGGATGCCCAGGATGCGCTCTACCTGCACTGGCGCGCTCTGA
CTGCTGCTCGAGCCCCACAGGCCGTCGAACTGACCCTGGCCTGGGCGGAAGGAGCCTCCTGCGCGGTGCGGATGGAGAGC
TCGGTGGAGCCCACCGCCGATCGGAGCCCCTGCCGGTTCCGATGTGCCCTGATGGATATTACGGAGCGTCGGCGCTCGGA
GGAGCAGCTTCGGATCGCCGCCCGCGTGTTCGAGGATGCCGGCGACGCGATCGTGGTGACGGACCCAGACGGTCACGTCC
AGACCATTAACAACGCCTTTACCCGAATCACGGGGTATACCGAGGGAGAGGCCCTGGGCAACACCGTGTGTGCCCTGCTC
GACTCCGGACGGCACAGCGAGGCCTTCCATAAGGAGAAGCAGGAGAGCCTGGACCGTTCAGGCTACTGGCAAGGCGAGAT
CTGGCACCGCCGCAAAGGCGGCGAGCTCTACCCGGAGTGGCTCACCATCAACCGTATCGATGACGCCACGGGCCAGCCCC
AGCACTTCGTGGCGGTCTTTTCGGATATCACTCAGCTTAAGGATGCCCACAGCAGGAGCGAGTACCTGGCCAACCACGAC
CCCCTGACCGGGTTGCCCAACCGCAGCCTGTTCCAGGACCGGCTTCAGCAGGCTATTGCTCAGACCCAGCGCCATGAGGG
GCAAGTGGGTCTGATGTTCCTGGATCTGGATCACTTCAAAACCATCAATGACACCCTCGGGCACGAGGTGGGGGATGAGC
TCCTGGTCCAGGTGGCTGAGCGACTGGGCGAACTGGTGCGGGATGTGGATACGGTCGCGCGGATCGGTGGCGACGAGTTC
ACCGTGGTGCTCACCGATTGCGACCCCGAGGAGGTTGGATCCATTGCGCAGCGCCTAGTGGAGGGCCTCGGTGGTACCTT
CGTGGTCGATGGCCGGGAGCTGCAGGCCACGCCCAGTGCCGGGTTGGCCTTGTATCCGCGCGATGGTGAGGATGTGCACA
CCCTGTGCAAGGCGGCCGATATGGCCATGTACCGGGCCAAGGAGGATGGCCGCAACCGGCTGCGGCTGTGCGAGTCTGGG
TTGCACCAGCGTCTCCTTAAGGATACTGCCCTGGAGGAGGCGCTGCGCCGGGCCCTCACGCAAGGTGAGCTGCGCCTCGT
CTATCAGCCCCAGTTCGACGCCAGCGACCCCGGCCGGGTGGTGGGGGCGGAGGCCCTGTTGCGTTGGCACGACCCCGCAT
CCGGACCGATCAGTCCGGGGCGGTTCATCCCCATTGCTGAGCGTTCCGATCTGATCCTGGAGCTGGATCGACGCGTGGAG
GAGCTATTGTGTGAACAGCTGAATACATGGTCGGCAGGCCATGCGCCCCCTGCTCCCATCTCGTTCAATGTCTCGGCCAA
GAGCTTTCGGCAGGGGCATTGGACCAAGCGGCTCTTCCGGATCCTGTCTCGCTACGGCGTTGCCGCCGAGCAGCTCCAGG
TGGAGTTCGCGGAGGGTACGCTCTCTGAGCGTGCCGGGGTCGTCCCGGAGGAGATCCGTCGGCTCCATGAGGGTGGCATC
GCCCTGGCCATCGACGATTTCGGGACTGGCTTCACCTCCTTGGTGAACCTCAAGCAACTCCCGCTGGCCGAACTCAAGAT
CGACCAATCCTTCGTGGCTGGACTGGGTCAGGATGAGGACGCCGAGGCGATCGTCCGGGCCAGCCTCGCCGTGGCCGAGG
CGATGGGGCTGAGGACTGTAGCTGAGGGCGTGGAGACCCAGCGGCAGTTGACCTGGTTGCAGGAGCAGGGCTGCCAACGC
ATCCAGGGCTCCCTCCTGAGCGCCCCCCTCGAAGCCGAGGATTTCGAGGCGCTGATCCGGGGCACACAAAAGCCCCCGCA
ATCACACTGA

Upstream 100 bases:

>100_bases
CGCCTAGACTCGAAAGACAGTGTGGCTCTGATCCCGCTCGACATGGATGTCGCGTAACGGAAGTCCTGACAATGAGATGG
CCTTAAAGGAACCCCCTTTG

Downstream 100 bases:

>100_bases
TACGCCGGCTCGGATGGATCCAAGGGAGGGTCACAGATGGTGCCGGGAGTGGGACTCGAACCCACATGGGCGAAGCCCAC
TCGATTTTGAGTCGAGCGCG

Product: PAS/PAC and GAF sensor-containing diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 749; Mature: 748

Protein sequence:

>749_residues
MGEDERRTLSPEALREAARRRLERRVTDVSDWSRADTQSLVAELELHQQELRIQNEELQQARDRLETALDRYHDLFQRAP
VGYLLLDDEGRIWEANRAAADLLAPGGDLTGQLLSDFVAVDAQDALYLHWRALTAARAPQAVELTLAWAEGASCAVRMES
SVEPTADRSPCRFRCALMDITERRRSEEQLRIAARVFEDAGDAIVVTDPDGHVQTINNAFTRITGYTEGEALGNTVCALL
DSGRHSEAFHKEKQESLDRSGYWQGEIWHRRKGGELYPEWLTINRIDDATGQPQHFVAVFSDITQLKDAHSRSEYLANHD
PLTGLPNRSLFQDRLQQAIAQTQRHEGQVGLMFLDLDHFKTINDTLGHEVGDELLVQVAERLGELVRDVDTVARIGGDEF
TVVLTDCDPEEVGSIAQRLVEGLGGTFVVDGRELQATPSAGLALYPRDGEDVHTLCKAADMAMYRAKEDGRNRLRLCESG
LHQRLLKDTALEEALRRALTQGELRLVYQPQFDASDPGRVVGAEALLRWHDPASGPISPGRFIPIAERSDLILELDRRVE
ELLCEQLNTWSAGHAPPAPISFNVSAKSFRQGHWTKRLFRILSRYGVAAEQLQVEFAEGTLSERAGVVPEEIRRLHEGGI
ALAIDDFGTGFTSLVNLKQLPLAELKIDQSFVAGLGQDEDAEAIVRASLAVAEAMGLRTVAEGVETQRQLTWLQEQGCQR
IQGSLLSAPLEAEDFEALIRGTQKPPQSH

Sequences:

>Translated_749_residues
MGEDERRTLSPEALREAARRRLERRVTDVSDWSRADTQSLVAELELHQQELRIQNEELQQARDRLETALDRYHDLFQRAP
VGYLLLDDEGRIWEANRAAADLLAPGGDLTGQLLSDFVAVDAQDALYLHWRALTAARAPQAVELTLAWAEGASCAVRMES
SVEPTADRSPCRFRCALMDITERRRSEEQLRIAARVFEDAGDAIVVTDPDGHVQTINNAFTRITGYTEGEALGNTVCALL
DSGRHSEAFHKEKQESLDRSGYWQGEIWHRRKGGELYPEWLTINRIDDATGQPQHFVAVFSDITQLKDAHSRSEYLANHD
PLTGLPNRSLFQDRLQQAIAQTQRHEGQVGLMFLDLDHFKTINDTLGHEVGDELLVQVAERLGELVRDVDTVARIGGDEF
TVVLTDCDPEEVGSIAQRLVEGLGGTFVVDGRELQATPSAGLALYPRDGEDVHTLCKAADMAMYRAKEDGRNRLRLCESG
LHQRLLKDTALEEALRRALTQGELRLVYQPQFDASDPGRVVGAEALLRWHDPASGPISPGRFIPIAERSDLILELDRRVE
ELLCEQLNTWSAGHAPPAPISFNVSAKSFRQGHWTKRLFRILSRYGVAAEQLQVEFAEGTLSERAGVVPEEIRRLHEGGI
ALAIDDFGTGFTSLVNLKQLPLAELKIDQSFVAGLGQDEDAEAIVRASLAVAEAMGLRTVAEGVETQRQLTWLQEQGCQR
IQGSLLSAPLEAEDFEALIRGTQKPPQSH
>Mature_748_residues
GEDERRTLSPEALREAARRRLERRVTDVSDWSRADTQSLVAELELHQQELRIQNEELQQARDRLETALDRYHDLFQRAPV
GYLLLDDEGRIWEANRAAADLLAPGGDLTGQLLSDFVAVDAQDALYLHWRALTAARAPQAVELTLAWAEGASCAVRMESS
VEPTADRSPCRFRCALMDITERRRSEEQLRIAARVFEDAGDAIVVTDPDGHVQTINNAFTRITGYTEGEALGNTVCALLD
SGRHSEAFHKEKQESLDRSGYWQGEIWHRRKGGELYPEWLTINRIDDATGQPQHFVAVFSDITQLKDAHSRSEYLANHDP
LTGLPNRSLFQDRLQQAIAQTQRHEGQVGLMFLDLDHFKTINDTLGHEVGDELLVQVAERLGELVRDVDTVARIGGDEFT
VVLTDCDPEEVGSIAQRLVEGLGGTFVVDGRELQATPSAGLALYPRDGEDVHTLCKAADMAMYRAKEDGRNRLRLCESGL
HQRLLKDTALEEALRRALTQGELRLVYQPQFDASDPGRVVGAEALLRWHDPASGPISPGRFIPIAERSDLILELDRRVEE
LLCEQLNTWSAGHAPPAPISFNVSAKSFRQGHWTKRLFRILSRYGVAAEQLQVEFAEGTLSERAGVVPEEIRRLHEGGIA
LAIDDFGTGFTSLVNLKQLPLAELKIDQSFVAGLGQDEDAEAIVRASLAVAEAMGLRTVAEGVETQRQLTWLQEQGCQRI
QGSLLSAPLEAEDFEALIRGTQKPPQSH

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=550, Percent_Identity=32.3636363636364, Blast_Score=267, Evalue=2e-72,
Organism=Escherichia coli, GI87081921, Length=448, Percent_Identity=31.4732142857143, Blast_Score=224, Evalue=1e-59,
Organism=Escherichia coli, GI1788381, Length=314, Percent_Identity=30.2547770700637, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI226510982, Length=420, Percent_Identity=26.6666666666667, Blast_Score=138, Evalue=1e-33,
Organism=Escherichia coli, GI1790496, Length=241, Percent_Identity=34.0248962655602, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI87081980, Length=257, Percent_Identity=35.7976653696498, Blast_Score=136, Evalue=4e-33,
Organism=Escherichia coli, GI87081845, Length=258, Percent_Identity=31.3953488372093, Blast_Score=127, Evalue=4e-30,
Organism=Escherichia coli, GI1786507, Length=248, Percent_Identity=34.6774193548387, Blast_Score=123, Evalue=4e-29,
Organism=Escherichia coli, GI1788502, Length=273, Percent_Identity=30.7692307692308, Blast_Score=122, Evalue=6e-29,
Organism=Escherichia coli, GI87081743, Length=241, Percent_Identity=32.7800829875519, Blast_Score=115, Evalue=8e-27,
Organism=Escherichia coli, GI1787055, Length=449, Percent_Identity=23.6080178173719, Blast_Score=112, Evalue=7e-26,
Organism=Escherichia coli, GI1786584, Length=174, Percent_Identity=32.7586206896552, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1787262, Length=211, Percent_Identity=34.1232227488152, Blast_Score=108, Evalue=2e-24,
Organism=Escherichia coli, GI87082096, Length=436, Percent_Identity=26.3761467889908, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI87081977, Length=182, Percent_Identity=32.4175824175824, Blast_Score=99, Evalue=8e-22,
Organism=Escherichia coli, GI145693134, Length=165, Percent_Identity=36.3636363636364, Blast_Score=99, Evalue=9e-22,
Organism=Escherichia coli, GI1788956, Length=152, Percent_Identity=37.5, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI1787802, Length=163, Percent_Identity=35.5828220858896, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI87081881, Length=179, Percent_Identity=34.0782122905028, Blast_Score=87, Evalue=6e-18,
Organism=Escherichia coli, GI1787816, Length=159, Percent_Identity=33.3333333333333, Blast_Score=86, Evalue=8e-18,
Organism=Escherichia coli, GI87082007, Length=175, Percent_Identity=30.2857142857143, Blast_Score=86, Evalue=1e-17,
Organism=Escherichia coli, GI1788849, Length=465, Percent_Identity=24.3010752688172, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI87081974, Length=154, Percent_Identity=29.2207792207792, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1788085, Length=218, Percent_Identity=26.1467889908257, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1787410, Length=122, Percent_Identity=30.327868852459, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1787056, Length=125, Percent_Identity=35.2, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1789650, Length=449, Percent_Identity=21.380846325167, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 83416; Mature: 83285

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGEDERRTLSPEALREAARRRLERRVTDVSDWSRADTQSLVAELELHQQELRIQNEELQQ
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
ARDRLETALDRYHDLFQRAPVGYLLLDDEGRIWEANRAAADLLAPGGDLTGQLLSDFVAV
HHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEECCHHHHHHHCCCCCCHHHHHHHHHHC
DAQDALYLHWRALTAARAPQAVELTLAWAEGASCAVRMESSVEPTADRSPCRFRCALMDI
CCCCHHEEHHHHHHHHCCCCEEEEEEEECCCCCEEEEECCCCCCCCCCCCCEEEHHHHHH
TERRRSEEQLRIAARVFEDAGDAIVVTDPDGHVQTINNAFTRITGYTEGEALGNTVCALL
HHHHCHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHH
DSGRHSEAFHKEKQESLDRSGYWQGEIWHRRKGGELYPEWLTINRIDDATGQPQHFVAVF
CCCCCHHHHHHHHHHHHHHCCCCCCCHHEECCCCCCCCCEEEEECCCCCCCCCHHHHHHH
SDITQLKDAHSRSEYLANHDPLTGLPNRSLFQDRLQQAIAQTQRHEGQVGLMFLDLDHFK
HHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHHHH
TINDTLGHEVGDELLVQVAERLGELVRDVDTVARIGGDEFTVVLTDCDPEEVGSIAQRLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHH
EGLGGTFVVDGRELQATPSAGLALYPRDGEDVHTLCKAADMAMYRAKEDGRNRLRLCESG
HHCCCEEEECCCEEECCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
LHQRLLKDTALEEALRRALTQGELRLVYQPQFDASDPGRVVGAEALLRWHDPASGPISPG
HHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCC
RFIPIAERSDLILELDRRVEELLCEQLNTWSAGHAPPAPISFNVSAKSFRQGHWTKRLFR
CEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHH
ILSRYGVAAEQLQVEFAEGTLSERAGVVPEEIRRLHEGGIALAIDDFGTGFTSLVNLKQL
HHHHHCCCHHHHHHHHHHCCHHHHCCCCHHHHHHHHCCCEEEEEECCCCCHHHHHHHHCC
PLAELKIDQSFVAGLGQDEDAEAIVRASLAVAEAMGLRTVAEGVETQRQLTWLQEQGCQR
CHHHHHCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IQGSLLSAPLEAEDFEALIRGTQKPPQSH
HHHHHHCCCCCHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
GEDERRTLSPEALREAARRRLERRVTDVSDWSRADTQSLVAELELHQQELRIQNEELQQ
CCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
ARDRLETALDRYHDLFQRAPVGYLLLDDEGRIWEANRAAADLLAPGGDLTGQLLSDFVAV
HHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEECCHHHHHHHCCCCCCHHHHHHHHHHC
DAQDALYLHWRALTAARAPQAVELTLAWAEGASCAVRMESSVEPTADRSPCRFRCALMDI
CCCCHHEEHHHHHHHHCCCCEEEEEEEECCCCCEEEEECCCCCCCCCCCCCEEEHHHHHH
TERRRSEEQLRIAARVFEDAGDAIVVTDPDGHVQTINNAFTRITGYTEGEALGNTVCALL
HHHHCHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHH
DSGRHSEAFHKEKQESLDRSGYWQGEIWHRRKGGELYPEWLTINRIDDATGQPQHFVAVF
CCCCCHHHHHHHHHHHHHHCCCCCCCHHEECCCCCCCCCEEEEECCCCCCCCCHHHHHHH
SDITQLKDAHSRSEYLANHDPLTGLPNRSLFQDRLQQAIAQTQRHEGQVGLMFLDLDHFK
HHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHHHH
TINDTLGHEVGDELLVQVAERLGELVRDVDTVARIGGDEFTVVLTDCDPEEVGSIAQRLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHH
EGLGGTFVVDGRELQATPSAGLALYPRDGEDVHTLCKAADMAMYRAKEDGRNRLRLCESG
HHCCCEEEECCCEEECCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
LHQRLLKDTALEEALRRALTQGELRLVYQPQFDASDPGRVVGAEALLRWHDPASGPISPG
HHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCC
RFIPIAERSDLILELDRRVEELLCEQLNTWSAGHAPPAPISFNVSAKSFRQGHWTKRLFR
CEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHH
ILSRYGVAAEQLQVEFAEGTLSERAGVVPEEIRRLHEGGIALAIDDFGTGFTSLVNLKQL
HHHHHCCCHHHHHHHHHHCCHHHHCCCCHHHHHHHHCCCEEEEEECCCCCHHHHHHHHCC
PLAELKIDQSFVAGLGQDEDAEAIVRASLAVAEAMGLRTVAEGVETQRQLTWLQEQGCQR
CHHHHHCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IQGSLLSAPLEAEDFEALIRGTQKPPQSH
HHHHHHCCCCCHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]