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The map label for this gene is mcpB [H]

Identifier: 121998493

GI number: 121998493

Start: 1875113

End: 1877134

Strand: Reverse

Name: mcpB [H]

Synonym: Hhal_1714

Alternate gene names: 121998493

Gene position: 1877134-1875113 (Counterclockwise)

Preceding gene: 121998494

Following gene: 121998492

Centisome position: 70.08

GC content: 68.05

Gene sequence:

>2022_bases
ATGCGCATCCGATGGAAGCTCGGTACGGGGTTCGGTCTGGTCATCGGTCTGGCCGGTGCTTTGGGTGCCGTGGCGGTATG
GCAGTTGGGGACCATTGACGACCACGCTACGGAGCTCCGCGAGGAGGTGTTGCCCGAGCTGCTGGCGGCACGGCAGATCG
AGGCATATGTGCAGCAGAGCGCCGAGCGCTGGCAGGAGTACGGTCTGACCCACCAACCCGAGGCTGCGGAGCGGGCCGCA
GAGGCCCACGATGCGGCCGTAGCGCAGATCGAGCAGGTGCGAGCCGGCAGTCACGGGCGCATGGCCGAGTTTGCCGAGCG
CGCCGAGGCCGCCATGGGGGCCTACCGCGATGCCACCGATGCCACGGAGGATGCCGTGGGGCGGTTGCGGGAGGAGCGGG
ACGGGCTGATGCGCTCAGCTACCATCGCCCTGGAAGAGACGCAGTACCTGCTGGATGAGCAGCGTGAGCGGGTCGAGGAC
GCCCAGGCGGCGGATTTCCGGGCGCCCGCCGGGCAGAGCGCTGCCGACGTACGCACCCGCCGGTTGCAGGATCTCTCGCG
CCTGAACGAGATCCGCGTGGTTACCGGGGACATCCACCGTGCCGCCCTGCAGTCTCTGGAAACCCGCGATCCGATACGGC
TGCAGGGCGCCCTGCCGGGGTTCGGGCAGGTCCAGGTGCACTTCAGTATCCTGCGCGCCAACGCCGCTGACGAGCAGGAG
CAACAGATCCTCGAGGAGATCAACGACGCGATTATCGAGTACCAGGATTACGCCACCGGACTGGCCGAGGCGCAGGAGGC
GCTGGCCGAGCTGCGCCATGTGCGGGCCGAGACCAGCGAGCAGGCCCTCGGGGCGGTGGTGGATCTGGCCAATCATACCG
CCGAGAATGGCGAGCGGGCCAGTGAGGGGGTCGTCGGCGTGGTCCGCGAGGCCGGGGCGACCCTGGGCATCGGGCTGTTT
CTGGTCGGCCTCCTGGCCTTCGGTATCGCGGCGTGGACCACGCGATCACTGACCCAGCCGCTGGGCCAGCTGGTCCATGG
CCTGCGCGACATCGCCGAGGGTGAGGGCGACTTGACCCGCCGGGTCGACGAGCGCCGGGCCGATGAACTGGGTGACGTTG
GCTATTGGTTCAACCGCCTGATGGATCGGATCCACGGCATGATCGTGCAGCTCTCCGGGGCGAGCCGGGATGTCACCGAC
GGCGTTGCGCGGATTGCCGCTAGCAATGCCCAGATCGAGTCGGGCATGACCGAGCAGTCGGATCAGACGCAGCAGGTCTC
CAGCGCCATCGAGGAGATGTCGAGTTCGATCCACGATGTCTCGCGCCAGACCAGCGAGGCGGCTAGTGCGGCGGTGCAGG
CCGGGGAGACGGCCGCCGATGGTCGAGAAACGGTCCAAGGTCTGGTGACCCGGATGCAGGAGGTCGCCGCCAGCGTCGAG
CGTGCCGGCGAGGCGGTGACCGCCCTTGGACACAGTGGCGAGCAGATCGGCGAGATCATCTCGATGATCGACGGCATCGC
CGAACAGACCAACCTGCTCGCTCTCAATGCTGCCATCGAGGCGGCCCGTGCCGGTGAGCAGGGGCGCGGTTTCGCCGTGG
TTGCCGACGAAGTACGCTCCCTGTCCCAGCGGACGGTGGATGCCACACAGCAGGTGTCCGAGGCGCTGCAGCAGATCCAG
GAGCGCACCGACACCGCCGTGCAGGGTATGCAGCAGAGTTCCGGGCAGGTCAACGACGGTCTGGGGCAGGCCGAGGCCGC
CGGGGCGGCCCTGCAACGAATTGTCGAGAAGGCACAGAGCGTCGCCGAGAACGTGCAGTCCATCGCGACGGCCGCCGAGC
AACAGTCGAATGTCGCCGCCGAGATCGCGCAGAATGTGGATGCGGTCAATCAGGTCACCCAGCAGACCAGCGGCGGCGTC
AACCAGGCCGCGCAGACCGCCCAGCAGCTGCGGCGTGAGGCCGAGGCCCTGCAGGAGTTGGTGCAGCAGTTCAAGGTGAC
AGAGGGTGGCCCGTCATCGTGA

Upstream 100 bases:

>100_bases
GGTCGCCACTGGTGATGACGGAGTCAGTCGCGTAGTTTATCGCGCGTTCTGAGGCATGGCTGCGGCGCTGCGGTCGCGGC
GGGGTGATAGGGAGAGCAGT

Downstream 100 bases:

>100_bases
CCGAGTGGCGCCGCAGTGACTTTGACTACGCCTTGCCCGAGCGGCTGATCGCCCATCGGCCGGCGGCGCAACGCGCCGCT
AGCCGGATGCTGGTGCTGCG

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: H3 [H]

Number of amino acids: Translated: 673; Mature: 673

Protein sequence:

>673_residues
MRIRWKLGTGFGLVIGLAGALGAVAVWQLGTIDDHATELREEVLPELLAARQIEAYVQQSAERWQEYGLTHQPEAAERAA
EAHDAAVAQIEQVRAGSHGRMAEFAERAEAAMGAYRDATDATEDAVGRLREERDGLMRSATIALEETQYLLDEQRERVED
AQAADFRAPAGQSAADVRTRRLQDLSRLNEIRVVTGDIHRAALQSLETRDPIRLQGALPGFGQVQVHFSILRANAADEQE
QQILEEINDAIIEYQDYATGLAEAQEALAELRHVRAETSEQALGAVVDLANHTAENGERASEGVVGVVREAGATLGIGLF
LVGLLAFGIAAWTTRSLTQPLGQLVHGLRDIAEGEGDLTRRVDERRADELGDVGYWFNRLMDRIHGMIVQLSGASRDVTD
GVARIAASNAQIESGMTEQSDQTQQVSSAIEEMSSSIHDVSRQTSEAASAAVQAGETAADGRETVQGLVTRMQEVAASVE
RAGEAVTALGHSGEQIGEIISMIDGIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLSQRTVDATQQVSEALQQIQ
ERTDTAVQGMQQSSGQVNDGLGQAEAAGAALQRIVEKAQSVAENVQSIATAAEQQSNVAAEIAQNVDAVNQVTQQTSGGV
NQAAQTAQQLRREAEALQELVQQFKVTEGGPSS

Sequences:

>Translated_673_residues
MRIRWKLGTGFGLVIGLAGALGAVAVWQLGTIDDHATELREEVLPELLAARQIEAYVQQSAERWQEYGLTHQPEAAERAA
EAHDAAVAQIEQVRAGSHGRMAEFAERAEAAMGAYRDATDATEDAVGRLREERDGLMRSATIALEETQYLLDEQRERVED
AQAADFRAPAGQSAADVRTRRLQDLSRLNEIRVVTGDIHRAALQSLETRDPIRLQGALPGFGQVQVHFSILRANAADEQE
QQILEEINDAIIEYQDYATGLAEAQEALAELRHVRAETSEQALGAVVDLANHTAENGERASEGVVGVVREAGATLGIGLF
LVGLLAFGIAAWTTRSLTQPLGQLVHGLRDIAEGEGDLTRRVDERRADELGDVGYWFNRLMDRIHGMIVQLSGASRDVTD
GVARIAASNAQIESGMTEQSDQTQQVSSAIEEMSSSIHDVSRQTSEAASAAVQAGETAADGRETVQGLVTRMQEVAASVE
RAGEAVTALGHSGEQIGEIISMIDGIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLSQRTVDATQQVSEALQQIQ
ERTDTAVQGMQQSSGQVNDGLGQAEAAGAALQRIVEKAQSVAENVQSIATAAEQQSNVAAEIAQNVDAVNQVTQQTSGGV
NQAAQTAQQLRREAEALQELVQQFKVTEGGPSS
>Mature_673_residues
MRIRWKLGTGFGLVIGLAGALGAVAVWQLGTIDDHATELREEVLPELLAARQIEAYVQQSAERWQEYGLTHQPEAAERAA
EAHDAAVAQIEQVRAGSHGRMAEFAERAEAAMGAYRDATDATEDAVGRLREERDGLMRSATIALEETQYLLDEQRERVED
AQAADFRAPAGQSAADVRTRRLQDLSRLNEIRVVTGDIHRAALQSLETRDPIRLQGALPGFGQVQVHFSILRANAADEQE
QQILEEINDAIIEYQDYATGLAEAQEALAELRHVRAETSEQALGAVVDLANHTAENGERASEGVVGVVREAGATLGIGLF
LVGLLAFGIAAWTTRSLTQPLGQLVHGLRDIAEGEGDLTRRVDERRADELGDVGYWFNRLMDRIHGMIVQLSGASRDVTD
GVARIAASNAQIESGMTEQSDQTQQVSSAIEEMSSSIHDVSRQTSEAASAAVQAGETAADGRETVQGLVTRMQEVAASVE
RAGEAVTALGHSGEQIGEIISMIDGIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLSQRTVDATQQVSEALQQIQ
ERTDTAVQGMQQSSGQVNDGLGQAEAAGAALQRIVEKAQSVAENVQSIATAAEQQSNVAAEIAQNVDAVNQVTQQTSGGV
NQAAQTAQQLRREAEALQELVQQFKVTEGGPSS

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788194, Length=361, Percent_Identity=32.9639889196676, Blast_Score=141, Evalue=2e-34,
Organism=Escherichia coli, GI1787690, Length=357, Percent_Identity=29.9719887955182, Blast_Score=136, Evalue=3e-33,
Organism=Escherichia coli, GI1788195, Length=306, Percent_Identity=32.0261437908497, Blast_Score=135, Evalue=1e-32,
Organism=Escherichia coli, GI2367378, Length=322, Percent_Identity=30.1242236024845, Blast_Score=133, Evalue=4e-32,
Organism=Escherichia coli, GI1789453, Length=341, Percent_Identity=28.7390029325513, Blast_Score=122, Evalue=5e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004010
- InterPro:   IPR003122
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR022094 [H]

Pfam domain/function: PF02743 Cache_1; PF00672 HAMP; PF12332 McpA_N; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 72005; Mature: 72005

Theoretical pI: Translated: 4.30; Mature: 4.30

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIRWKLGTGFGLVIGLAGALGAVAVWQLGTIDDHATELREEVLPELLAARQIEAYVQQS
CEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AERWQEYGLTHQPEAAERAAEAHDAAVAQIEQVRAGSHGRMAEFAERAEAAMGAYRDATD
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCC
ATEDAVGRLREERDGLMRSATIALEETQYLLDEQRERVEDAQAADFRAPAGQSAADVRTR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
RLQDLSRLNEIRVVTGDIHRAALQSLETRDPIRLQGALPGFGQVQVHFSILRANAADEQE
HHHHHHHHHHHHHHEHHHHHHHHHHHCCCCCCEEECCCCCCCHHEEHHHHHHCCCCCHHH
QQILEEINDAIIEYQDYATGLAEAQEALAELRHVRAETSEQALGAVVDLANHTAENGERA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
SEGVVGVVREAGATLGIGLFLVGLLAFGIAAWTTRSLTQPLGQLVHGLRDIAEGEGDLTR
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
RVDERRADELGDVGYWFNRLMDRIHGMIVQLSGASRDVTDGVARIAASNAQIESGMTEQS
HHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHCCHHHHCCCCCCC
DQTQQVSSAIEEMSSSIHDVSRQTSEAASAAVQAGETAADGRETVQGLVTRMQEVAASVE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
RAGEAVTALGHSGEQIGEIISMIDGIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRS
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHH
LSQRTVDATQQVSEALQQIQERTDTAVQGMQQSSGQVNDGLGQAEAAGAALQRIVEKAQS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHH
VAENVQSIATAAEQQSNVAAEIAQNVDAVNQVTQQTSGGVNQAAQTAQQLRREAEALQEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
VQQFKVTEGGPSS
HHHHCCCCCCCCC
>Mature Secondary Structure
MRIRWKLGTGFGLVIGLAGALGAVAVWQLGTIDDHATELREEVLPELLAARQIEAYVQQS
CEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AERWQEYGLTHQPEAAERAAEAHDAAVAQIEQVRAGSHGRMAEFAERAEAAMGAYRDATD
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCC
ATEDAVGRLREERDGLMRSATIALEETQYLLDEQRERVEDAQAADFRAPAGQSAADVRTR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
RLQDLSRLNEIRVVTGDIHRAALQSLETRDPIRLQGALPGFGQVQVHFSILRANAADEQE
HHHHHHHHHHHHHHEHHHHHHHHHHHCCCCCCEEECCCCCCCHHEEHHHHHHCCCCCHHH
QQILEEINDAIIEYQDYATGLAEAQEALAELRHVRAETSEQALGAVVDLANHTAENGERA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
SEGVVGVVREAGATLGIGLFLVGLLAFGIAAWTTRSLTQPLGQLVHGLRDIAEGEGDLTR
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
RVDERRADELGDVGYWFNRLMDRIHGMIVQLSGASRDVTDGVARIAASNAQIESGMTEQS
HHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHCCHHHHCCCCCCC
DQTQQVSSAIEEMSSSIHDVSRQTSEAASAAVQAGETAADGRETVQGLVTRMQEVAASVE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
RAGEAVTALGHSGEQIGEIISMIDGIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRS
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHH
LSQRTVDATQQVSEALQQIQERTDTAVQGMQQSSGQVNDGLGQAEAAGAALQRIVEKAQS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHH
VAENVQSIATAAEQQSNVAAEIAQNVDAVNQVTQQTSGGVNQAAQTAQQLRREAEALQEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
VQQFKVTEGGPSS
HHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8188684; 9384377 [H]