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The map label for this gene is etfA [H]

Identifier: 121998276

GI number: 121998276

Start: 1615192

End: 1616130

Strand: Reverse

Name: etfA [H]

Synonym: Hhal_1494

Alternate gene names: 121998276

Gene position: 1616130-1615192 (Counterclockwise)

Preceding gene: 121998277

Following gene: 121998275

Centisome position: 60.34

GC content: 69.65

Gene sequence:

>939_bases
ATGAGTGTCCTGGTCTTTGCGGAACATGATGGCGCCCGGGTCACCGAGGCGACGCGACGGGCGATCAGCGCCGCCACCAC
CCTGGGCACGCCGGTCGATGTGGTGGTCGCTGGCGGCGAAGAGGCAGCCAGTGTCGCGGAATCGCTGGCCGTTGCCGGCG
TCAATCGGGTGTGGCTGTGCCTTGGGGCGATCTATGCGGATCAGCTGGCCGAGCCGCTGGCCGAGCGGGTATCGAGGCTG
ATCCAGGATGAGGGTTATCAGGCGCTGGTTGCTGCCACCAGCACCCAGGCGCGGGACCTACTGCCCCGTATCGCGGCGGC
GCTCGACGTCCAGATGCTCTCGGATGTCATTGCCATCGAGGACACCGAGACCTTCGTGCGCCCCATCCACGGGGGCAGCG
TCCTGGCCCGCCTGCGCTGTCGAGAGCCGGTCAAGGTGCTCACCGTGCGGGCCACCCGGTTCGAGCGGCCGGAGGCGGGG
GATCTGCCGGCCGTGGAGCGCCTCGAGGCGGGGACGGAGTCGGGGCCGACCCGCCTGCTGGAAGAGCACGGCAGCGCTTC
GGACCGTCCCGATCTGGCCTCGGCTCGAGTGGTGGTCGCCGGCGGACGCGGGGTCGCCGATGTCGGGATCGAAGAGCTGG
AGGCGCTGGCGGATCAGCTCGGTGCGGCCATCGGGGCCTCGCGCGGGGCCGTCGAGGCCGGCCTGCTGCCCAACGAGGCG
CAGGTGGGGCTAACTGCCAAGGTAGTGGCTCCGGAGCTTTACATCGCCGCGGGCATCTCCGGTGCGATCTACCACGTGTC
CGGGATGAAGGACAGTGGGGTCATCGTGGCGATCAACAAGGATCCCGAGGCGCCCATCTTCGAGGTGGCCGACTACGGCC
TGGTTGCCGACCTGCGGGAAGCCCTTCCCGCGCTGCGCACTGCACTGGAGCAGGCATGA

Upstream 100 bases:

>100_bases
CTCGGGGTCTCGGAGCCGCCGCCGCGTGCGGCCGGTGAGCGGGTCGAGAGCGTGGCCGAACTGGTTGACCGTCTGAAGAA
CGACGCGCAGGTGATTTGAG

Downstream 100 bases:

>100_bases
GCATGTACCGCGCACCGACTCGCGATCTGCGTTTCGTCATCGAAGAACTGATCGGCCTGGAGCGTTTTTCCGGGCTGCAG
GATCTGGAAGAGATCACCCC

Product: electron transfer flavoprotein subunit alpha

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 312; Mature: 311

Protein sequence:

>312_residues
MSVLVFAEHDGARVTEATRRAISAATTLGTPVDVVVAGGEEAASVAESLAVAGVNRVWLCLGAIYADQLAEPLAERVSRL
IQDEGYQALVAATSTQARDLLPRIAAALDVQMLSDVIAIEDTETFVRPIHGGSVLARLRCREPVKVLTVRATRFERPEAG
DLPAVERLEAGTESGPTRLLEEHGSASDRPDLASARVVVAGGRGVADVGIEELEALADQLGAAIGASRGAVEAGLLPNEA
QVGLTAKVVAPELYIAAGISGAIYHVSGMKDSGVIVAINKDPEAPIFEVADYGLVADLREALPALRTALEQA

Sequences:

>Translated_312_residues
MSVLVFAEHDGARVTEATRRAISAATTLGTPVDVVVAGGEEAASVAESLAVAGVNRVWLCLGAIYADQLAEPLAERVSRL
IQDEGYQALVAATSTQARDLLPRIAAALDVQMLSDVIAIEDTETFVRPIHGGSVLARLRCREPVKVLTVRATRFERPEAG
DLPAVERLEAGTESGPTRLLEEHGSASDRPDLASARVVVAGGRGVADVGIEELEALADQLGAAIGASRGAVEAGLLPNEA
QVGLTAKVVAPELYIAAGISGAIYHVSGMKDSGVIVAINKDPEAPIFEVADYGLVADLREALPALRTALEQA
>Mature_311_residues
SVLVFAEHDGARVTEATRRAISAATTLGTPVDVVVAGGEEAASVAESLAVAGVNRVWLCLGAIYADQLAEPLAERVSRLI
QDEGYQALVAATSTQARDLLPRIAAALDVQMLSDVIAIEDTETFVRPIHGGSVLARLRCREPVKVLTVRATRFERPEAGD
LPAVERLEAGTESGPTRLLEEHGSASDRPDLASARVVVAGGRGVADVGIEELEALADQLGAAIGASRGAVEAGLLPNEAQ
VGLTAKVVAPELYIAAGISGAIYHVSGMKDSGVIVAINKDPEAPIFEVADYGLVADLREALPALRTALEQA

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=313, Percent_Identity=45.6869009584665, Blast_Score=248, Evalue=7e-66,
Organism=Homo sapiens, GI189181759, Length=278, Percent_Identity=46.0431654676259, Blast_Score=229, Evalue=3e-60,
Organism=Escherichia coli, GI1786226, Length=270, Percent_Identity=34.8148148148148, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1787990, Length=252, Percent_Identity=30.1587301587302, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI87082157, Length=250, Percent_Identity=28.8, Blast_Score=77, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17506929, Length=315, Percent_Identity=46.6666666666667, Blast_Score=249, Evalue=1e-66,
Organism=Saccharomyces cerevisiae, GI6325261, Length=319, Percent_Identity=38.871473354232, Blast_Score=202, Evalue=7e-53,
Organism=Drosophila melanogaster, GI17136898, Length=313, Percent_Identity=45.6869009584665, Blast_Score=237, Evalue=6e-63,
Organism=Drosophila melanogaster, GI24652801, Length=313, Percent_Identity=45.6869009584665, Blast_Score=237, Evalue=6e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 32422; Mature: 32291

Theoretical pI: Translated: 4.38; Mature: 4.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLVFAEHDGARVTEATRRAISAATTLGTPVDVVVAGGEEAASVAESLAVAGVNRVWLC
CEEEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHCHHHHHHH
LGAIYADQLAEPLAERVSRLIQDEGYQALVAATSTQARDLLPRIAAALDVQMLSDVIAIE
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCC
DTETFVRPIHGGSVLARLRCREPVKVLTVRATRFERPEAGDLPAVERLEAGTESGPTRLL
CCHHHHHCCCCCHHHHHHHCCCCCEEEEEEHHHCCCCCCCCCCHHHHHHCCCCCCHHHHH
EEHGSASDRPDLASARVVVAGGRGVADVGIEELEALADQLGAAIGASRGAVEAGLLPNEA
HHCCCCCCCCCCCCCEEEEECCCCCHHCCHHHHHHHHHHHHHHHCCCCCCEECCCCCCCC
QVGLTAKVVAPELYIAAGISGAIYHVSGMKDSGVIVAINKDPEAPIFEVADYGLVADLRE
CCCEEEEECCCCEEEEECCCCEEEEECCCCCCCEEEEECCCCCCCHHHHHCCHHHHHHHH
ALPALRTALEQA
HHHHHHHHHHCC
>Mature Secondary Structure 
SVLVFAEHDGARVTEATRRAISAATTLGTPVDVVVAGGEEAASVAESLAVAGVNRVWLC
EEEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHCHHHHHHH
LGAIYADQLAEPLAERVSRLIQDEGYQALVAATSTQARDLLPRIAAALDVQMLSDVIAIE
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCC
DTETFVRPIHGGSVLARLRCREPVKVLTVRATRFERPEAGDLPAVERLEAGTESGPTRLL
CCHHHHHCCCCCHHHHHHHCCCCCEEEEEEHHHCCCCCCCCCCHHHHHHCCCCCCHHHHH
EEHGSASDRPDLASARVVVAGGRGVADVGIEELEALADQLGAAIGASRGAVEAGLLPNEA
HHCCCCCCCCCCCCCEEEEECCCCCHHCCHHHHHHHHHHHHHHHCCCCCCEECCCCCCCC
QVGLTAKVVAPELYIAAGISGAIYHVSGMKDSGVIVAINKDPEAPIFEVADYGLVADLRE
CCCEEEEECCCCEEEEECCCCEEEEECCCCCCCEEEEECCCCCCCHHHHHCCHHHHHHHH
ALPALRTALEQA
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]