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The map label for this gene is accA

Identifier: 121998225

GI number: 121998225

Start: 1555775

End: 1556731

Strand: Reverse

Name: accA

Synonym: Hhal_1443

Alternate gene names: 121998225

Gene position: 1556731-1555775 (Counterclockwise)

Preceding gene: 121998226

Following gene: 121998224

Centisome position: 58.12

GC content: 66.67

Gene sequence:

>957_bases
ATGACCAAGAACTTTCTGGATTTTGAGCAGCCGATCGCCGAACTTGAGGCCAAGATCGAAGAGCTGCGCAACGTCGGCCA
GGATTCCGAGGTCAACATCAACGAGGAGATCCAGCGCCTCGAGGCCAAGAGCCGCTCGCTGACGGAGAAGATCTTCTCCT
CGCTGAGCGCCTGGCAGATCGTGCAGCTGGCCCGTCACCCCGAGCGCCCCTACCTCTTCGACTACATCGAGCGCATCTTC
ACCGATTTCCAGGAGTTGCACGGGGATCGGGCCTACGCGGACGATGCCGCGATCGCCGGCGGCGTGGCCCGTTTCGACGG
GCGGCCGGTGATGGTTATCGGGCAACAGAAGGGGCGGGATACCAAGGAGAAGGTGCGCCGCAACTTCGGTATGCCCCGTC
CCGAGGGGTACCGCAAGGCGCTGCGGCTGATGCGCATGGCCGAGCGCTTCGGGCTGCCGATCTTCACCTTCATCGATACG
CCGGGCGCCTATCCCGGGGTCGGGGCCGAGGAGCGCGGACAGAGCGAAGCTATCGCCCGCAATCTTGCCGAGATGGCCCA
ACTGCGCGTGCCGGTGATCTGCACGGTGGTGGGTGAGGGCGGATCGGGCGGGGCGCTGGCAATCAGTGTCGGCAACCGGC
TGCTGATGCTGCGCTACTCGGTCTATTCGGTGATCTCGCCCGAGGGGTGCGCCTCAATCCTGTGGAAGAGTTCGGAGCGG
GCCGCCGATGCCGCCGAGGCGATGCAGATGGCGGCCGAACGGCTCCACGACCTGGGCATCGTCGATCGCGTCATCCCCGA
GCCGCTGGGCGGTGCCCACCGCGATTACGAAGCCATGGCCGAGACGCTGCGCGAGGCGCTCCGCGAGGAGTGGGCGCGGG
TCGGCCAGATGAGCCCGGATGAACTGGTGGCGGACCGCCACCAGCGCCTTGCCGCGATCGGCCAGCCCCAGGGGTAA

Upstream 100 bases:

>100_bases
CCCGCCGTCCCCACAGGGGTTTCGCTTCTGGTAAGGTACGGCCAGCACGCAGGCTGCCTGCGGTATTCGCCCGCCCATCC
GAGAGGTCAACGGGGAGCTC

Downstream 100 bases:

>100_bases
CGGCCGTGCTGGACCGCCGGGTGCTGGTGGCTCGATTGCTGGGCCTGGCGCCCGCGGCCGCGGCTTACCGCGTCGCGTTC
AGCGGCGGGCGGGACTCCAC

Product: acetyl-CoA carboxylase, carboxyl transferase subunit alpha

Products: NA

Alternate protein names: ACCase subunit alpha; Acetyl-CoA carboxylase carboxyltransferase subunit alpha

Number of amino acids: Translated: 318; Mature: 317

Protein sequence:

>318_residues
MTKNFLDFEQPIAELEAKIEELRNVGQDSEVNINEEIQRLEAKSRSLTEKIFSSLSAWQIVQLARHPERPYLFDYIERIF
TDFQELHGDRAYADDAAIAGGVARFDGRPVMVIGQQKGRDTKEKVRRNFGMPRPEGYRKALRLMRMAERFGLPIFTFIDT
PGAYPGVGAEERGQSEAIARNLAEMAQLRVPVICTVVGEGGSGGALAISVGNRLLMLRYSVYSVISPEGCASILWKSSER
AADAAEAMQMAAERLHDLGIVDRVIPEPLGGAHRDYEAMAETLREALREEWARVGQMSPDELVADRHQRLAAIGQPQG

Sequences:

>Translated_318_residues
MTKNFLDFEQPIAELEAKIEELRNVGQDSEVNINEEIQRLEAKSRSLTEKIFSSLSAWQIVQLARHPERPYLFDYIERIF
TDFQELHGDRAYADDAAIAGGVARFDGRPVMVIGQQKGRDTKEKVRRNFGMPRPEGYRKALRLMRMAERFGLPIFTFIDT
PGAYPGVGAEERGQSEAIARNLAEMAQLRVPVICTVVGEGGSGGALAISVGNRLLMLRYSVYSVISPEGCASILWKSSER
AADAAEAMQMAAERLHDLGIVDRVIPEPLGGAHRDYEAMAETLREALREEWARVGQMSPDELVADRHQRLAAIGQPQG
>Mature_317_residues
TKNFLDFEQPIAELEAKIEELRNVGQDSEVNINEEIQRLEAKSRSLTEKIFSSLSAWQIVQLARHPERPYLFDYIERIFT
DFQELHGDRAYADDAAIAGGVARFDGRPVMVIGQQKGRDTKEKVRRNFGMPRPEGYRKALRLMRMAERFGLPIFTFIDTP
GAYPGVGAEERGQSEAIARNLAEMAQLRVPVICTVVGEGGSGGALAISVGNRLLMLRYSVYSVISPEGCASILWKSSERA
ADAAEAMQMAAERLHDLGIVDRVIPEPLGGAHRDYEAMAETLREALREEWARVGQMSPDELVADRHQRLAAIGQPQG

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-Co

COG id: COG0825

COG function: function code I; Acetyl-CoA carboxylase alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccA family

Homologues:

Organism=Escherichia coli, GI1786382, Length=317, Percent_Identity=66.8769716088328, Blast_Score=436, Evalue=1e-124,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACCA_HALHL (A1WWZ8)

Other databases:

- EMBL:   CP000544
- RefSeq:   YP_001003012.1
- ProteinModelPortal:   A1WWZ8
- SMR:   A1WWZ8
- STRING:   A1WWZ8
- GeneID:   4709316
- GenomeReviews:   CP000544_GR
- KEGG:   hha:Hhal_1443
- eggNOG:   COG0825
- HOGENOM:   HBG286557
- OMA:   QLTKDIY
- PhylomeDB:   A1WWZ8
- BioCyc:   HHAL349124:HHAL_1443-MONOMER
- HAMAP:   MF_00823
- InterPro:   IPR001095
- InterPro:   IPR011763
- PANTHER:   PTHR22855:SF3
- PRINTS:   PR01069
- TIGRFAMs:   TIGR00513

Pfam domain/function: PF03255 ACCA

EC number: =6.4.1.2

Molecular weight: Translated: 35444; Mature: 35313

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKNFLDFEQPIAELEAKIEELRNVGQDSEVNINEEIQRLEAKSRSLTEKIFSSLSAWQI
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VQLARHPERPYLFDYIERIFTDFQELHGDRAYADDAAIAGGVARFDGRPVMVIGQQKGRD
HHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHCCHHHHHCCHHHCCCCEEEEECCCCCCC
TKEKVRRNFGMPRPEGYRKALRLMRMAERFGLPIFTFIDTPGAYPGVGAEERGQSEAIAR
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHCCHHHHHHH
NLAEMAQLRVPVICTVVGEGGSGGALAISVGNRLLMLRYSVYSVISPEGCASILWKSSER
HHHHHHHCCCCEEEEEEECCCCCCEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHCCCHH
AADAAEAMQMAAERLHDLGIVDRVIPEPLGGAHRDYEAMAETLREALREEWARVGQMSPD
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHH
ELVADRHQRLAAIGQPQG
HHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TKNFLDFEQPIAELEAKIEELRNVGQDSEVNINEEIQRLEAKSRSLTEKIFSSLSAWQI
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VQLARHPERPYLFDYIERIFTDFQELHGDRAYADDAAIAGGVARFDGRPVMVIGQQKGRD
HHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHCCHHHHHCCHHHCCCCEEEEECCCCCCC
TKEKVRRNFGMPRPEGYRKALRLMRMAERFGLPIFTFIDTPGAYPGVGAEERGQSEAIAR
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHCCHHHHHHH
NLAEMAQLRVPVICTVVGEGGSGGALAISVGNRLLMLRYSVYSVISPEGCASILWKSSER
HHHHHHHCCCCEEEEEEECCCCCCEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHCCCHH
AADAAEAMQMAAERLHDLGIVDRVIPEPLGGAHRDYEAMAETLREALREEWARVGQMSPD
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHH
ELVADRHQRLAAIGQPQG
HHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA