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The map label for this gene is ftsK [H]

Identifier: 121998178

GI number: 121998178

Start: 1507690

End: 1510203

Strand: Reverse

Name: ftsK [H]

Synonym: Hhal_1396

Alternate gene names: 121998178

Gene position: 1510203-1507690 (Counterclockwise)

Preceding gene: 121998182

Following gene: 121998176

Centisome position: 56.38

GC content: 67.82

Gene sequence:

>2514_bases
GTGGTCACTGACAATGATGGATTGATTCCTGCAAAGAGTAAGCGATCCGTGGCGGAGCCGGAAGAACAACGCGGGGACGA
ACCGTTTCTCGGCCATCAACTGCAGCGTCGCCTGCGCGAGGCGGCCATGGTGCTGCTCGGCGGCGTGGCCGCCTTCATGC
TTCTGGCCCTGTGGAGTTACGACGCCGACGACCCGAGTTGGAGCCGCGTGACCGCGGTGGCCGATGTCGATAACTTCGGC
GGGATCGCTGGTGCCTGGTTCGCCGATATCGCGCTGGTGCTGTTCGGTTATCTGGCCTTCCTGGTGCCCCTGTTCATGGG
GTGGGCCGCCTACCGTGTGTTCCGCATGCTGGATGAGCCCGGGTTTGACCCGCTGGCACTGACCGTCCGCTCGGTGGGGC
TTCTCCTGGCGCTCTTGGCCGGTGCTGCGCTGGCCAGCCTGCACTTCGAGGGCGAGGCGCTGCCCTTAGGGGCGGGCGGG
TTGCTCGGTGAGCTGAGTGCCGGCGAGTTGGAGAGCTGGTTGGGGTTCGTGGGGGCGTCGCTGATGGCCGGTGCCCTGTT
CCTCGCGGCGCTGACCCTGGCTACCGGTTTCTCCTGGCTCGCCCTGTCCGAGTGGGTGGGGCGCTGGACGCTGGCGTTCG
CGCGGTGGTTACGGCATGTCATCTATCGGCTCTTCGTCGGCGGCGCTCTCCGCGGCCTGGGTGGTCTGCGCGCACTGCGC
CGGCGGGCGGCCGAGCGGCGCGATGAGCGGACGGCCGCCCGCCAGGAGCAAGCGGCGACACCGCGCATTGCGCCGCCTGC
GGACCAGGAAGAGGGTGGGGCGGTACGCAAGGCGATCCGGCTGCTCCCTCGCTCCCGCAGCGAGGGGCCGCCGGAACAGG
TCATCGACCCACCGCCGGTGCAGCGCGAATCGGCCGCCACGGAGAAACCCCGCCGGCCTCGCAAGGCGGAGCGCAAACGC
AGTCAATCCGCCGGTGGGGGTGGCTCGCCGGTGCCGCCCGTGGAGCTGCTTGACGAGCCACCGACCGGCAAGGGGGGCTA
CAGCCGGGAGGCGCTGGCGACCATGTCGCAACAGGTTGAGGAGCGGCTGCGCGACTTCGGCGTCGAGGTCCAGGTGGAGA
CCGTACAGCCCGGGCCGGTGATCACCCGCTTCGAGGTTTTGCCGGCTGCCGGCGTGAAGGTCAGCCAGATCTCCAACCTG
GCCAAGGACCTGGCGCGGGCCATGTCCGTGCGTTCAGTCCGCGTGGTCGAGGTCATCCCCGGTAAGTCCACCGTGGGGCT
GGAGATCCCCAACGAGCAGCGGGACGTCATCGCGCTCTCGGAGATCATCCGCTCCCAGGAGTACGGGCGCATGAAGTCGG
CGCTAACGGTGGCGCTGGGCAAGGACATCGGTGGCAATCCGGTAACGGCCGATCTGGCCAAGATGCCGCACCTGCTCGTG
GCCGGCACCACCGGGTCCGGAAAATCGGTGGGGATCAACGCCATGATCCTCTCACTGCTCTACCGCAACACGCCGGAGCA
GACCCGACTGATCATGGTCGACCCGAAGATGCTGGAGCTCTCCGTCTACGACGGCATCCCGCATCTCCTCGCGCCGGTGG
TCACCGACATGAATGATGCCGCCAACGCCTTGCGCTGGTGCGTGGCCGAGATGGAACGGCGCTACCGCCTGATGGCGGCG
CTCGGGGTGCGCAACGTCACCGGTTTCAACGACAAGGTGCGTGCGGCGCGTGAGGCCGGCGAGCCGCTGCTCGATCCGCT
GTTCGATGCCGGCGATCCCAACGAGCAGACATTGGATAGTGACACCCCGCAGGCCCCGGAGCTCGAGGAGCTTCCGTTCA
TTGTGGTGGTGGTGGACGAGTTGGCCGACATGATGATGATCGTCGGCAAGAAGGTCGAGGAACTCATCGCGCGGCTCGCG
CAGAAGGCTCGGGCCGCAGGCATCCATCTGATCCTAGCGACCCAGCGCCCGTCGGTGGATGTGATCACCGGCCTGATCAA
GGCCAACATCCCGACCCGGATGGCCTATCAGGTTTCTTCCAAGGTCGATTCGCGCACCATCCTCGATCAGCAAGGTGCCG
AGGCCTTGCTCGGCCACGGCGACATGCTCTACGTACCGCCGGGGAGCGGGATGCCCCAGCGCGTGCACGGCGCCTTTGTC
TCCGACGCCGAGGTGCATCGGGTGGTGGAGCATCTCAAGGCGGTGGCCGAACCGGAATACCTGGACGAGGTGCTTCAGGA
CGCCAGCGAGTCGGCACCCATCCCCGGCCTGCCCGGCGAGGGGAGCGGCAGCAGTGGCGGGGGCGGTGGGGAGAGCGACC
CGCTCTACGATGACGCTGTGCGTATCGTCACCGAGACGCGTCGGGCCTCCATCTCTGGCGTGCAGCGGCGGTTGAAGATC
GGCTACAACCGCGCCGCGCGACTGGTCGAGGAGATGGAGTCCGCCGGGGTGGTCGGTCCGCTGCAATCCAATGGCGGTCG
CGAAGTCCTGGCGCCGCCGCCCCCGGACGCCTAA

Upstream 100 bases:

>100_bases
TCTCCTCTCCTCGGGCAGGTTCGCCTCGAAGCGTCCTTGCATGATACCGCCCGGCTCCGGCGTCGTGCAGTCGTCGGCCG
GGCGACTTGCCGCTGCCGCG

Downstream 100 bases:

>100_bases
GCGGCTGGATCAGGCCCTGGCGGCCAGGCGTTCCGTGCCGGCGCCACCGATGGCGTTGCCGCCGTCCGCCTTGACGGCGT
ACATCCGCTGATCGGCGGCG

Product: cell divisionFtsK/SpoIIIE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 837; Mature: 837

Protein sequence:

>837_residues
MVTDNDGLIPAKSKRSVAEPEEQRGDEPFLGHQLQRRLREAAMVLLGGVAAFMLLALWSYDADDPSWSRVTAVADVDNFG
GIAGAWFADIALVLFGYLAFLVPLFMGWAAYRVFRMLDEPGFDPLALTVRSVGLLLALLAGAALASLHFEGEALPLGAGG
LLGELSAGELESWLGFVGASLMAGALFLAALTLATGFSWLALSEWVGRWTLAFARWLRHVIYRLFVGGALRGLGGLRALR
RRAAERRDERTAARQEQAATPRIAPPADQEEGGAVRKAIRLLPRSRSEGPPEQVIDPPPVQRESAATEKPRRPRKAERKR
SQSAGGGGSPVPPVELLDEPPTGKGGYSREALATMSQQVEERLRDFGVEVQVETVQPGPVITRFEVLPAAGVKVSQISNL
AKDLARAMSVRSVRVVEVIPGKSTVGLEIPNEQRDVIALSEIIRSQEYGRMKSALTVALGKDIGGNPVTADLAKMPHLLV
AGTTGSGKSVGINAMILSLLYRNTPEQTRLIMVDPKMLELSVYDGIPHLLAPVVTDMNDAANALRWCVAEMERRYRLMAA
LGVRNVTGFNDKVRAAREAGEPLLDPLFDAGDPNEQTLDSDTPQAPELEELPFIVVVVDELADMMMIVGKKVEELIARLA
QKARAAGIHLILATQRPSVDVITGLIKANIPTRMAYQVSSKVDSRTILDQQGAEALLGHGDMLYVPPGSGMPQRVHGAFV
SDAEVHRVVEHLKAVAEPEYLDEVLQDASESAPIPGLPGEGSGSSGGGGGESDPLYDDAVRIVTETRRASISGVQRRLKI
GYNRAARLVEEMESAGVVGPLQSNGGREVLAPPPPDA

Sequences:

>Translated_837_residues
MVTDNDGLIPAKSKRSVAEPEEQRGDEPFLGHQLQRRLREAAMVLLGGVAAFMLLALWSYDADDPSWSRVTAVADVDNFG
GIAGAWFADIALVLFGYLAFLVPLFMGWAAYRVFRMLDEPGFDPLALTVRSVGLLLALLAGAALASLHFEGEALPLGAGG
LLGELSAGELESWLGFVGASLMAGALFLAALTLATGFSWLALSEWVGRWTLAFARWLRHVIYRLFVGGALRGLGGLRALR
RRAAERRDERTAARQEQAATPRIAPPADQEEGGAVRKAIRLLPRSRSEGPPEQVIDPPPVQRESAATEKPRRPRKAERKR
SQSAGGGGSPVPPVELLDEPPTGKGGYSREALATMSQQVEERLRDFGVEVQVETVQPGPVITRFEVLPAAGVKVSQISNL
AKDLARAMSVRSVRVVEVIPGKSTVGLEIPNEQRDVIALSEIIRSQEYGRMKSALTVALGKDIGGNPVTADLAKMPHLLV
AGTTGSGKSVGINAMILSLLYRNTPEQTRLIMVDPKMLELSVYDGIPHLLAPVVTDMNDAANALRWCVAEMERRYRLMAA
LGVRNVTGFNDKVRAAREAGEPLLDPLFDAGDPNEQTLDSDTPQAPELEELPFIVVVVDELADMMMIVGKKVEELIARLA
QKARAAGIHLILATQRPSVDVITGLIKANIPTRMAYQVSSKVDSRTILDQQGAEALLGHGDMLYVPPGSGMPQRVHGAFV
SDAEVHRVVEHLKAVAEPEYLDEVLQDASESAPIPGLPGEGSGSSGGGGGESDPLYDDAVRIVTETRRASISGVQRRLKI
GYNRAARLVEEMESAGVVGPLQSNGGREVLAPPPPDA
>Mature_837_residues
MVTDNDGLIPAKSKRSVAEPEEQRGDEPFLGHQLQRRLREAAMVLLGGVAAFMLLALWSYDADDPSWSRVTAVADVDNFG
GIAGAWFADIALVLFGYLAFLVPLFMGWAAYRVFRMLDEPGFDPLALTVRSVGLLLALLAGAALASLHFEGEALPLGAGG
LLGELSAGELESWLGFVGASLMAGALFLAALTLATGFSWLALSEWVGRWTLAFARWLRHVIYRLFVGGALRGLGGLRALR
RRAAERRDERTAARQEQAATPRIAPPADQEEGGAVRKAIRLLPRSRSEGPPEQVIDPPPVQRESAATEKPRRPRKAERKR
SQSAGGGGSPVPPVELLDEPPTGKGGYSREALATMSQQVEERLRDFGVEVQVETVQPGPVITRFEVLPAAGVKVSQISNL
AKDLARAMSVRSVRVVEVIPGKSTVGLEIPNEQRDVIALSEIIRSQEYGRMKSALTVALGKDIGGNPVTADLAKMPHLLV
AGTTGSGKSVGINAMILSLLYRNTPEQTRLIMVDPKMLELSVYDGIPHLLAPVVTDMNDAANALRWCVAEMERRYRLMAA
LGVRNVTGFNDKVRAAREAGEPLLDPLFDAGDPNEQTLDSDTPQAPELEELPFIVVVVDELADMMMIVGKKVEELIARLA
QKARAAGIHLILATQRPSVDVITGLIKANIPTRMAYQVSSKVDSRTILDQQGAEALLGHGDMLYVPPGSGMPQRVHGAFV
SDAEVHRVVEHLKAVAEPEYLDEVLQDASESAPIPGLPGEGSGSSGGGGGESDPLYDDAVRIVTETRRASISGVQRRLKI
GYNRAARLVEEMESAGVVGPLQSNGGREVLAPPPPDA

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=510, Percent_Identity=61.1764705882353, Blast_Score=603, Evalue=1e-173,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018541
- InterPro:   IPR002543 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 89886; Mature: 89886

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTDNDGLIPAKSKRSVAEPEEQRGDEPFLGHQLQRRLREAAMVLLGGVAAFMLLALWSY
CCCCCCCCCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DADDPSWSRVTAVADVDNFGGIAGAWFADIALVLFGYLAFLVPLFMGWAAYRVFRMLDEP
CCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GFDPLALTVRSVGLLLALLAGAALASLHFEGEALPLGAGGLLGELSAGELESWLGFVGAS
CCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEECCCCCHHCCCCHHHHHHHHHHHHHH
LMAGALFLAALTLATGFSWLALSEWVGRWTLAFARWLRHVIYRLFVGGALRGLGGLRALR
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRAAERRDERTAARQEQAATPRIAPPADQEEGGAVRKAIRLLPRSRSEGPPEQVIDPPPV
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHCCCCCCC
QRESAATEKPRRPRKAERKRSQSAGGGGSPVPPVELLDEPPTGKGGYSREALATMSQQVE
CCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHH
ERLRDFGVEVQVETVQPGPVITRFEVLPAAGVKVSQISNLAKDLARAMSVRSVRVVEVIP
HHHHHCCCEEEEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEEC
GKSTVGLEIPNEQRDVIALSEIIRSQEYGRMKSALTVALGKDIGGNPVTADLAKMPHLLV
CCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCEEE
AGTTGSGKSVGINAMILSLLYRNTPEQTRLIMVDPKMLELSVYDGIPHLLAPVVTDMNDA
EECCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEHHCCCHHHHHHHHHCCHHH
ANALRWCVAEMERRYRLMAALGVRNVTGFNDKVRAAREAGEPLLDPLFDAGDPNEQTLDS
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHHHHCCCCCCCCCCCC
DTPQAPELEELPFIVVVVDELADMMMIVGKKVEELIARLAQKARAAGIHLILATQRPSVD
CCCCCCCHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHH
VITGLIKANIPTRMAYQVSSKVDSRTILDQQGAEALLGHGDMLYVPPGSGMPQRVHGAFV
HHHHHHHCCCCHHHHHHHHHCCCHHHHHHHCCCHHHHCCCCEEEECCCCCCCHHHHCCCC
SDAEVHRVVEHLKAVAEPEYLDEVLQDASESAPIPGLPGEGSGSSGGGGGESDPLYDDAV
CHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHH
RIVTETRRASISGVQRRLKIGYNRAARLVEEMESAGVVGPLQSNGGREVLAPPPPDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCCCCC
>Mature Secondary Structure
MVTDNDGLIPAKSKRSVAEPEEQRGDEPFLGHQLQRRLREAAMVLLGGVAAFMLLALWSY
CCCCCCCCCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DADDPSWSRVTAVADVDNFGGIAGAWFADIALVLFGYLAFLVPLFMGWAAYRVFRMLDEP
CCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GFDPLALTVRSVGLLLALLAGAALASLHFEGEALPLGAGGLLGELSAGELESWLGFVGAS
CCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEECCCCCHHCCCCHHHHHHHHHHHHHH
LMAGALFLAALTLATGFSWLALSEWVGRWTLAFARWLRHVIYRLFVGGALRGLGGLRALR
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRAAERRDERTAARQEQAATPRIAPPADQEEGGAVRKAIRLLPRSRSEGPPEQVIDPPPV
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHCCCCCCC
QRESAATEKPRRPRKAERKRSQSAGGGGSPVPPVELLDEPPTGKGGYSREALATMSQQVE
CCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHH
ERLRDFGVEVQVETVQPGPVITRFEVLPAAGVKVSQISNLAKDLARAMSVRSVRVVEVIP
HHHHHCCCEEEEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEEC
GKSTVGLEIPNEQRDVIALSEIIRSQEYGRMKSALTVALGKDIGGNPVTADLAKMPHLLV
CCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCEEE
AGTTGSGKSVGINAMILSLLYRNTPEQTRLIMVDPKMLELSVYDGIPHLLAPVVTDMNDA
EECCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEHHCCCHHHHHHHHHCCHHH
ANALRWCVAEMERRYRLMAALGVRNVTGFNDKVRAAREAGEPLLDPLFDAGDPNEQTLDS
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHHHHCCCCCCCCCCCC
DTPQAPELEELPFIVVVVDELADMMMIVGKKVEELIARLAQKARAAGIHLILATQRPSVD
CCCCCCCHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHH
VITGLIKANIPTRMAYQVSSKVDSRTILDQQGAEALLGHGDMLYVPPGSGMPQRVHGAFV
HHHHHHHCCCCHHHHHHHHHCCCHHHHHHHCCCHHHHCCCCEEEECCCCCCCHHHHCCCC
SDAEVHRVVEHLKAVAEPEYLDEVLQDASESAPIPGLPGEGSGSSGGGGGESDPLYDDAV
CHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHH
RIVTETRRASISGVQRRLKIGYNRAARLVEEMESAGVVGPLQSNGGREVLAPPPPDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12928499 [H]