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The map label for this gene is lolA

Identifier: 121998176

GI number: 121998176

Start: 1505692

End: 1506318

Strand: Reverse

Name: lolA

Synonym: Hhal_1394

Alternate gene names: 121998176

Gene position: 1506318-1505692 (Counterclockwise)

Preceding gene: 121998178

Following gene: 121998175

Centisome position: 56.24

GC content: 66.83

Gene sequence:

>627_bases
ATGAAACGAACCGCAACCCTCCTCGTCGTCGCGCTGATACTGGCCCTGAACACCGCCCAGGCCGGGCAGCTACAGGCGCT
GGAGGACTACTACCGCGACGTGGAGACCGTGCAGGGGGTATTCAACCAGTTTACGCTGGATGACCGGGGGCAGGTGATCG
AGGAGTCCTCCGGCGACTTTGCCATCCACCGCCCGGACCGTTTCCACTGGTCCTACGCCGGGCCGTTCTCCCAGGAGATC
ATTGCTGACGGTGAGCGGCTGTGGGTCTACGACGTGGAGCTCGATCAGGTGACCGTGCGGGATCAGCGCGCCGTCCTCGG
CAGTGCGCCGGCGCAGCTGCTCTCCGGCGACTACGCGGATCTCGAGGAACTCTTCGAGCTGGCCGAGACGGAGGACTACG
TCCGGCTCACCCCCCGAGACGGCGGCGAGGCGTTCGACGAGGCCCGACTGGGCATGCGTGACGGCCACCCGAGCGCCCTG
GAGATCGACGACGCCCTAGGGCAAGTGACCCGGGTCGAACTCGACGAGGTGCGGCTCAACGATGCCGTGGACGAAGAGCG
CTTCCGCTTCGAGCCGCCCGAGGGGGTGGATGTCTACGAGGCCGATCCGGACGAGGGCATCCGTTGA

Upstream 100 bases:

>100_bases
GCCCGGCCTGCTGGCACCGGGGCGTGACGCCCCGCGTCAGCAGGGCTATCCTGAACGGTTGGATTGGCGCATCTGCACGC
AACCTAGAGGCACGACGCCC

Downstream 100 bases:

>100_bases
CGGCAGCGCCAAGCGCACCGCTGGCCGAGCGCATGCGCCCGAGGAGCATCGAGGAGATGGCCGGGCAGGGCCACCTTCTC
GATACCGGTCGCGCGCTCGC

Product: outer membrane lipoprotein carrier protein LolA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 208; Mature: 208

Protein sequence:

>208_residues
MKRTATLLVVALILALNTAQAGQLQALEDYYRDVETVQGVFNQFTLDDRGQVIEESSGDFAIHRPDRFHWSYAGPFSQEI
IADGERLWVYDVELDQVTVRDQRAVLGSAPAQLLSGDYADLEELFELAETEDYVRLTPRDGGEAFDEARLGMRDGHPSAL
EIDDALGQVTRVELDEVRLNDAVDEERFRFEPPEGVDVYEADPDEGIR

Sequences:

>Translated_208_residues
MKRTATLLVVALILALNTAQAGQLQALEDYYRDVETVQGVFNQFTLDDRGQVIEESSGDFAIHRPDRFHWSYAGPFSQEI
IADGERLWVYDVELDQVTVRDQRAVLGSAPAQLLSGDYADLEELFELAETEDYVRLTPRDGGEAFDEARLGMRDGHPSAL
EIDDALGQVTRVELDEVRLNDAVDEERFRFEPPEGVDVYEADPDEGIR
>Mature_208_residues
MKRTATLLVVALILALNTAQAGQLQALEDYYRDVETVQGVFNQFTLDDRGQVIEESSGDFAIHRPDRFHWSYAGPFSQEI
IADGERLWVYDVELDQVTVRDQRAVLGSAPAQLLSGDYADLEELFELAETEDYVRLTPRDGGEAFDEARLGMRDGHPSAL
EIDDALGQVTRVELDEVRLNDAVDEERFRFEPPEGVDVYEADPDEGIR

Specific function: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the l

COG id: COG2834

COG function: function code M; Outer membrane lipoprotein-sorting protein

Gene ontology:

Cell location: Periplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lolA family

Homologues:

Organism=Escherichia coli, GI145693108, Length=202, Percent_Identity=26.7326732673267, Blast_Score=81, Evalue=5e-17,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): LOLA_HALHL (A1WWU9)

Other databases:

- EMBL:   CP000544
- RefSeq:   YP_001002963.1
- ProteinModelPortal:   A1WWU9
- SMR:   A1WWU9
- STRING:   A1WWU9
- GeneID:   4711280
- GenomeReviews:   CP000544_GR
- KEGG:   hha:Hhal_1394
- eggNOG:   COG2834
- HOGENOM:   HBG688940
- OMA:   GERLWVY
- PhylomeDB:   A1WWU9
- ProtClustDB:   CLSK727458
- BioCyc:   HHAL349124:HHAL_1394-MONOMER
- HAMAP:   MF_00240
- InterPro:   IPR004564
- InterPro:   IPR018323
- TIGRFAMs:   TIGR00547

Pfam domain/function: PF03548 LolA

EC number: NA

Molecular weight: Translated: 23438; Mature: 23438

Theoretical pI: Translated: 3.92; Mature: 3.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRTATLLVVALILALNTAQAGQLQALEDYYRDVETVQGVFNQFTLDDRGQVIEESSGDF
CCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCE
AIHRPDRFHWSYAGPFSQEIIADGERLWVYDVELDQVTVRDQRAVLGSAPAQLLSGDYAD
EEECCCCCCEEECCCCHHHHHCCCCEEEEEEEEECEEEHHHHHHHHCCCCHHHHCCCCCC
LEELFELAETEDYVRLTPRDGGEAFDEARLGMRDGHPSALEIDDALGQVTRVELDEVRLN
HHHHHHHHCCCCEEEECCCCCCHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHC
DAVDEERFRFEPPEGVDVYEADPDEGIR
CCCCCHHHCCCCCCCCCCEECCCCCCCC
>Mature Secondary Structure
MKRTATLLVVALILALNTAQAGQLQALEDYYRDVETVQGVFNQFTLDDRGQVIEESSGDF
CCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCE
AIHRPDRFHWSYAGPFSQEIIADGERLWVYDVELDQVTVRDQRAVLGSAPAQLLSGDYAD
EEECCCCCCEEECCCCHHHHHCCCCEEEEEEEEECEEEHHHHHHHHCCCCHHHHCCCCCC
LEELFELAETEDYVRLTPRDGGEAFDEARLGMRDGHPSALEIDDALGQVTRVELDEVRLN
HHHHHHHHCCCCEEEECCCCCCHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHC
DAVDEERFRFEPPEGVDVYEADPDEGIR
CCCCCHHHCCCCCCCCCCEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA