Click here to switch to the map view.

The map label for this gene is nrdR

Identifier: 121997692

GI number: 121997692

Start: 976750

End: 977217

Strand: Reverse

Name: nrdR

Synonym: Hhal_0901

Alternate gene names: 121997692

Gene position: 977217-976750 (Counterclockwise)

Preceding gene: 121997693

Following gene: 121997691

Centisome position: 36.48

GC content: 69.87

Gene sequence:

>468_bases
ATGCGCTGCCCGTACTGCCAGAACGCTGACACCCGCGTGGTCGACTCGCGCCTGATCGGCGAGGGCGAGCAAGTGCGGCG
GCGGCGGCAGTGCCCGTCCTGTGGCGAGCGCTTCACCACCCACGAGGCCCCCGAGCTGGTCTACCCGCGGGTGGTGAAGT
CCGACGGGCGGCGCGAGGCGTTCGACGAGGACAAACTGCGTCTCGGTTTCCGGCGGGCGCTGGAGAAACGCCCGGTGGCC
ACCGAGGCTGTCGAGGCGGCGGTGCGGCGTGTCTGTAAGCGCGTCTCCGGCGCCGGCGAGCGCGAAGTGGCCGCCAACGT
CATCGGCGAGTACGTCATGGAAGAGCTGCGCGAGCTCGACGTGGTCGCCTATGTCCGTTTCGCCTCGGTCTACCGGCGCT
TCGAGGATGTCGGCGCCTTCCGCGAGGTCATTGAGGGCCTGGAGCAGCACCGGCGTGACGACGACTGA

Upstream 100 bases:

>100_bases
ACATGGGCGACGAGTCCGTCGTCGAGCGCGTGCGCGGCGAGGTGGAGCAGATCTGTCGCGAATTCCCCGTCTACGGGTGA
CGCGGGACGCCTGATCGACC

Downstream 100 bases:

>100_bases
CCGGCACCCGGACGATCCCCGCTGGATGGCCCGCGCCATTCGGCGGGCGGCCGCGGTATGCCCGCCGCCGCACCCCAATC
CGCGGGTCGGCTGCGTGCTG

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 155; Mature: 155

Protein sequence:

>155_residues
MRCPYCQNADTRVVDSRLIGEGEQVRRRRQCPSCGERFTTHEAPELVYPRVVKSDGRREAFDEDKLRLGFRRALEKRPVA
TEAVEAAVRRVCKRVSGAGEREVAANVIGEYVMEELRELDVVAYVRFASVYRRFEDVGAFREVIEGLEQHRRDDD

Sequences:

>Translated_155_residues
MRCPYCQNADTRVVDSRLIGEGEQVRRRRQCPSCGERFTTHEAPELVYPRVVKSDGRREAFDEDKLRLGFRRALEKRPVA
TEAVEAAVRRVCKRVSGAGEREVAANVIGEYVMEELRELDVVAYVRFASVYRRFEDVGAFREVIEGLEQHRRDDD
>Mature_155_residues
MRCPYCQNADTRVVDSRLIGEGEQVRRRRQCPSCGERFTTHEAPELVYPRVVKSDGRREAFDEDKLRLGFRRALEKRPVA
TEAVEAAVRRVCKRVSGAGEREVAANVIGEYVMEELRELDVVAYVRFASVYRRFEDVGAFREVIEGLEQHRRDDD

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain

Homologues:

Organism=Escherichia coli, GI1786615, Length=148, Percent_Identity=58.7837837837838, Blast_Score=176, Evalue=4e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NRDR_HALHL (A1WVG5)

Other databases:

- EMBL:   CP000544
- RefSeq:   YP_001002479.1
- STRING:   A1WVG5
- GeneID:   4709319
- GenomeReviews:   CP000544_GR
- KEGG:   hha:Hhal_0901
- eggNOG:   COG1327
- HOGENOM:   HBG351755
- OMA:   FASVYRD
- PhylomeDB:   A1WVG5
- ProtClustDB:   PRK00464
- BioCyc:   HHAL349124:HHAL_0901-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_00440
- InterPro:   IPR005144
- InterPro:   IPR003796
- TIGRFAMs:   TIGR00244

Pfam domain/function: PF03477 ATP-cone

EC number: NA

Molecular weight: Translated: 17935; Mature: 17935

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRCPYCQNADTRVVDSRLIGEGEQVRRRRQCPSCGERFTTHEAPELVYPRVVKSDGRREA
CCCCCCCCCCHHHHHHHHHCCCHHHHHHHCCCCHHHHHCCCCCCHHHHHHHHHCCCCCCC
FDEDKLRLGFRRALEKRPVATEAVEAAVRRVCKRVSGAGEREVAANVIGEYVMEELRELD
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
VVAYVRFASVYRRFEDVGAFREVIEGLEQHRRDDD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRCPYCQNADTRVVDSRLIGEGEQVRRRRQCPSCGERFTTHEAPELVYPRVVKSDGRREA
CCCCCCCCCCHHHHHHHHHCCCHHHHHHHCCCCHHHHHCCCCCCHHHHHHHHHCCCCCCC
FDEDKLRLGFRRALEKRPVATEAVEAAVRRVCKRVSGAGEREVAANVIGEYVMEELRELD
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
VVAYVRFASVYRRFEDVGAFREVIEGLEQHRRDDD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA