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The map label for this gene is nuoC

Identifier: 121639030

GI number: 121639030

Start: 3465675

End: 3466385

Strand: Direct

Name: nuoC

Synonym: BCG_3170

Alternate gene names: 121639030

Gene position: 3465675-3466385 (Clockwise)

Preceding gene: 121639029

Following gene: 121639031

Centisome position: 79.22

GC content: 66.39

Gene sequence:

>711_bases
ATGAGCCCGCCGAACCAAGACGCCCAGGAAGGCCGCCCGGACTCCCCCACCGCGGAGGTGGTCGACGTTCGCCGCGGCAT
GTTCGGCGTCTCGGGCACCGGTGACACCTCCGGTTACGGACGGTTGGTGCGCCAAGTCGTCCTCCCTGGCAGCAGCCCCC
GGCCCTACGGCGGCTACTTCGACGATATCGTCGACCGGCTGGCCGAGGCACTGCGGCACGAGCGCGTCGAATTCGAGGAC
GCCGTCGAGAAAGTCGTGGTCTACCGCGATGAACTGACCCTGCACGTCCGCCGGGATCTACTGCCGCGGGTCGCCCAGCG
GCTGCGCGACGAACCCGAATTGCGATTCGAGCTGTGTCTTGGGGTGAGCGGGGTGCACTACCCGCACGAGACGGGTCGGG
AGCTGCATGCCGTCTACCCGCTGCAGTCGATCACCCACAACCGTCGCCTCCGGTTGGAAGTGTCTGCGCCGGACAGTGAT
CCGCACATCCCTTCCCTGTTCGCGATCTATCCGACCAACGACTGGCACGAGCGGGAAACCTACGACTTCTTCGGGATCAT
CTTCGACGGCCATCCGGCCCTGACCCGGATCGAGATGCCCGATGACTGGCAGGGGCATCCGCAACGCAAGGACTACCCTC
TCGGCGGCATCCCGGTCGAATACAAGGGCGCGCAGATACCCCCGCCCGACGAGCGGAGGGGCTACAACTGA

Upstream 100 bases:

>100_bases
AGCAGATGCCATTAGGTATCAACCGGGAACGCGCTATCGCCGAGGCCGAAGAGGCGGCGTTGTTGGCCCGGCCCACCATC
GAGATGCGCGGACTGCTGCG

Downstream 100 bases:

>100_bases
TGACGGCAATCGCCGACTCGGCTGGCGGCGCCGGCGAGACCGTCCTGGTCGCTGGCGGGCAGGACTGGCAGCAGGTCGTG
GACGCCGCGCGCAGCGCGGA

Product: NADH dehydrogenase subunit C

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C; NDH-1 subunit C

Number of amino acids: Translated: 236; Mature: 235

Protein sequence:

>236_residues
MSPPNQDAQEGRPDSPTAEVVDVRRGMFGVSGTGDTSGYGRLVRQVVLPGSSPRPYGGYFDDIVDRLAEALRHERVEFED
AVEKVVVYRDELTLHVRRDLLPRVAQRLRDEPELRFELCLGVSGVHYPHETGRELHAVYPLQSITHNRRLRLEVSAPDSD
PHIPSLFAIYPTNDWHERETYDFFGIIFDGHPALTRIEMPDDWQGHPQRKDYPLGGIPVEYKGAQIPPPDERRGYN

Sequences:

>Translated_236_residues
MSPPNQDAQEGRPDSPTAEVVDVRRGMFGVSGTGDTSGYGRLVRQVVLPGSSPRPYGGYFDDIVDRLAEALRHERVEFED
AVEKVVVYRDELTLHVRRDLLPRVAQRLRDEPELRFELCLGVSGVHYPHETGRELHAVYPLQSITHNRRLRLEVSAPDSD
PHIPSLFAIYPTNDWHERETYDFFGIIFDGHPALTRIEMPDDWQGHPQRKDYPLGGIPVEYKGAQIPPPDERRGYN
>Mature_235_residues
SPPNQDAQEGRPDSPTAEVVDVRRGMFGVSGTGDTSGYGRLVRQVVLPGSSPRPYGGYFDDIVDRLAEALRHERVEFEDA
VEKVVVYRDELTLHVRRDLLPRVAQRLRDEPELRFELCLGVSGVHYPHETGRELHAVYPLQSITHNRRLRLEVSAPDSDP
HIPSLFAIYPTNDWHERETYDFFGIIFDGHPALTRIEMPDDWQGHPQRKDYPLGGIPVEYKGAQIPPPDERRGYN

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translo

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family

Homologues:

Organism=Homo sapiens, GI4758788, Length=200, Percent_Identity=31, Blast_Score=78, Evalue=8e-15,
Organism=Escherichia coli, GI145693162, Length=124, Percent_Identity=39.5161290322581, Blast_Score=96, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71990788, Length=127, Percent_Identity=34.6456692913386, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI32563621, Length=153, Percent_Identity=32.6797385620915, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24656494, Length=127, Percent_Identity=33.0708661417323, Blast_Score=78, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOC_MYCBO (P65572)

Other databases:

- EMBL:   BX248345
- RefSeq:   NP_856816.1
- ProteinModelPortal:   P65572
- SMR:   P65572
- EnsemblBacteria:   EBMYCT00000014768
- GeneID:   1093222
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb3171
- GeneTree:   EBGT00050000017747
- HOGENOM:   HBG727675
- OMA:   VYPTNDW
- ProtClustDB:   PRK07785
- BioCyc:   MBOV233413:MB3171-MONOMER
- BRENDA:   1.6.99.5
- GO:   GO:0006810
- HAMAP:   MF_01357
- InterPro:   IPR010218
- InterPro:   IPR001268
- ProDom:   PD001581
- TIGRFAMs:   TIGR01961

Pfam domain/function: PF00329 Complex1_30kDa

EC number: =1.6.99.5

Molecular weight: Translated: 26932; Mature: 26801

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: PS00542 COMPLEX1_30K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPPNQDAQEGRPDSPTAEVVDVRRGMFGVSGTGDTSGYGRLVRQVVLPGSSPRPYGGYF
CCCCCCCHHCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHH
DDIVDRLAEALRHERVEFEDAVEKVVVYRDELTLHVRRDLLPRVAQRLRDEPELRFELCL
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEE
GVSGVHYPHETGRELHAVYPLQSITHNRRLRLEVSAPDSDPHIPSLFAIYPTNDWHERET
CCCCCCCCCCCCCCEEEECCHHHHCCCCEEEEEEECCCCCCCCCEEEEEECCCCCCCCCC
YDFFGIIFDGHPALTRIEMPDDWQGHPQRKDYPLGGIPVEYKGAQIPPPDERRGYN
EEEEEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SPPNQDAQEGRPDSPTAEVVDVRRGMFGVSGTGDTSGYGRLVRQVVLPGSSPRPYGGYF
CCCCCCHHCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHH
DDIVDRLAEALRHERVEFEDAVEKVVVYRDELTLHVRRDLLPRVAQRLRDEPELRFELCL
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEE
GVSGVHYPHETGRELHAVYPLQSITHNRRLRLEVSAPDSDPHIPSLFAIYPTNDWHERET
CCCCCCCCCCCCCCEEEECCHHHHCCCCEEEEEEECCCCCCCCCEEEEEECCCCCCCCCC
YDFFGIIFDGHPALTRIEMPDDWQGHPQRKDYPLGGIPVEYKGAQIPPPDERRGYN
EEEEEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12788972