Click here to switch to the map view.

The map label for this gene is narL

Identifier: 121636767

GI number: 121636767

Start: 970962

End: 971612

Strand: Reverse

Name: narL

Synonym: BCG_0896c

Alternate gene names: 121636767

Gene position: 971612-970962 (Counterclockwise)

Preceding gene: 121636769

Following gene: 121636763

Centisome position: 22.21

GC content: 67.74

Gene sequence:

>651_bases
ATGAGCAATCCGCAGCCGGAGAAAGTGCGCGTGGTGGTCGGCGACGACCACCCGTTATTTCGCGAGGGCGTTGTGCGAGC
GCTTTCGTTGAGTGGCTCGGTGAACGTGGTCGGCGAGGCCGACGACGGCGCCGCGGCCCTGGAGTTGATCAAGGCCCATT
TGCCCGACGTCGCATTGCTGGACTACCGCATGCCCGGCATGGACGGCGCGCAGGTTGCGGCGGCGGTGCGCAGCTACGAG
TTGCCAACCCGGGTGCTGCTTATTTCCGCGCACGACGAGCCGGCGATCGTCTACCAGGCACTCCAACAGGGCGCCGCCGG
ATTCCTGCTCAAGGATTCGACTCGCACCGAGATCGTCAAGGCGGTGCTCGATTGCGCGAAGGGCCGCGACGTGGTGGCGC
CCTCGCTGGTCGGGGGCCTCGCCGGGGAGATTCGCCAGCGCGCGGCACCCGTGGCCCCGGTGCTCAGCGCGCGCGAGCGC
GAGGTGCTCAATCGCATTGCGTGCGGTCAAAGCATCCCCGCGATCGCAGCCGAGCTATATGTGGCGCCGTCGACGGTAAA
GACCCACGTGCAACGGTTGTACGAGAAGCTCGGCGTCAGCGACCGAGCTGCCGCGGTCGCCGAGGCGATGCGGCAGAGGC
TGCTCGACTAG

Upstream 100 bases:

>100_bases
TTGCCGTAGCTGGGCACGTCGGAGTGCAAATCAATGTCCAGCGACTGCCAGCGGCTGGTTGCCGACGAGCAGCTAAACTC
ATCGCCATGGTCGGCGCGCC

Downstream 100 bases:

>100_bases
CTGGGGCCGCGGCGCGACGGCATGTACCGACCGCGTTGTCCGCGGCCAACGTACATCTAGGCCTCAGAACCGGGTCTTTG
GTTGTTGGTGCCAGCCGGAT

Product: putative nitrate/nitrite response transcriptional regulatory protein narL

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 216; Mature: 215

Protein sequence:

>216_residues
MSNPQPEKVRVVVGDDHPLFREGVVRALSLSGSVNVVGEADDGAAALELIKAHLPDVALLDYRMPGMDGAQVAAAVRSYE
LPTRVLLISAHDEPAIVYQALQQGAAGFLLKDSTRTEIVKAVLDCAKGRDVVAPSLVGGLAGEIRQRAAPVAPVLSARER
EVLNRIACGQSIPAIAAELYVAPSTVKTHVQRLYEKLGVSDRAAAVAEAMRQRLLD

Sequences:

>Translated_216_residues
MSNPQPEKVRVVVGDDHPLFREGVVRALSLSGSVNVVGEADDGAAALELIKAHLPDVALLDYRMPGMDGAQVAAAVRSYE
LPTRVLLISAHDEPAIVYQALQQGAAGFLLKDSTRTEIVKAVLDCAKGRDVVAPSLVGGLAGEIRQRAAPVAPVLSARER
EVLNRIACGQSIPAIAAELYVAPSTVKTHVQRLYEKLGVSDRAAAVAEAMRQRLLD
>Mature_215_residues
SNPQPEKVRVVVGDDHPLFREGVVRALSLSGSVNVVGEADDGAAALELIKAHLPDVALLDYRMPGMDGAQVAAAVRSYEL
PTRVLLISAHDEPAIVYQALQQGAAGFLLKDSTRTEIVKAVLDCAKGRDVVAPSLVGGLAGEIRQRAAPVAPVLSARERE
VLNRIACGQSIPAIAAELYVAPSTVKTHVQRLYEKLGVSDRAAAVAEAMRQRLLD

Specific function: Probable member of the two-component regulatory system NarS/NarL

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain

Homologues:

Organism=Escherichia coli, GI1788521, Length=212, Percent_Identity=35.8490566037736, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI1787473, Length=218, Percent_Identity=35.3211009174312, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1788222, Length=211, Percent_Identity=28.436018957346, Blast_Score=96, Evalue=1e-21,
Organism=Escherichia coli, GI1790102, Length=195, Percent_Identity=35.3846153846154, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1786747, Length=189, Percent_Identity=25.3968253968254, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1788712, Length=203, Percent_Identity=24.6305418719212, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1788546, Length=208, Percent_Identity=26.4423076923077, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NARL_MYCTU (O53856)

Other databases:

- EMBL:   BX842574
- EMBL:   AE000516
- PIR:   D70813
- RefSeq:   NP_215359.1
- RefSeq:   NP_335295.1
- PDB:   3EUL
- PDBsum:   3EUL
- ProteinModelPortal:   O53856
- SMR:   O53856
- EnsemblBacteria:   EBMYCT00000003985
- EnsemblBacteria:   EBMYCT00000071880
- GeneID:   885603
- GeneID:   926175
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT0866
- KEGG:   mtu:Rv0844c
- TIGR:   MT0866
- TubercuList:   Rv0844c
- GeneTree:   EBGT00050000014817
- HOGENOM:   HBG753323
- OMA:   ESAIVYQ
- ProtClustDB:   CLSK790779
- GO:   GO:0005737
- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PRINTS:   PR00038
- SMART:   SM00421
- SMART:   SM00448

Pfam domain/function: PF00196 GerE; PF00072 Response_reg; SSF46894 Bipartite_resp_reg_C-effector; SSF52172 CheY_like

EC number: NA

Molecular weight: Translated: 22917; Mature: 22785

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00622 HTH_LUXR_1; PS50043 HTH_LUXR_2; PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNPQPEKVRVVVGDDHPLFREGVVRALSLSGSVNVVGEADDGAAALELIKAHLPDVALL
CCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCEEEE
DYRMPGMDGAQVAAAVRSYELPTRVLLISAHDEPAIVYQALQQGAAGFLLKDSTRTEIVK
ECCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHCCCCCEEEECCHHHHHHH
AVLDCAKGRDVVAPSLVGGLAGEIRQRAAPVAPVLSAREREVLNRIACGQSIPAIAAELY
HHHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
VAPSTVKTHVQRLYEKLGVSDRAAAVAEAMRQRLLD
CCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SNPQPEKVRVVVGDDHPLFREGVVRALSLSGSVNVVGEADDGAAALELIKAHLPDVALL
CCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCEEEE
DYRMPGMDGAQVAAAVRSYELPTRVLLISAHDEPAIVYQALQQGAAGFLLKDSTRTEIVK
ECCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHCCCCCEEEECCHHHHHHH
AVLDCAKGRDVVAPSLVGGLAGEIRQRAAPVAPVLSAREREVLNRIACGQSIPAIAAELY
HHHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
VAPSTVKTHVQRLYEKLGVSDRAAAVAEAMRQRLLD
CCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036