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The map label for this gene is pip [H]

Identifier: 121636763

GI number: 121636763

Start: 966963

End: 967823

Strand: Reverse

Name: pip [H]

Synonym: BCG_0892c

Alternate gene names: 121636763

Gene position: 967823-966963 (Counterclockwise)

Preceding gene: 121636767

Following gene: 121636760

Centisome position: 22.12

GC content: 60.98

Gene sequence:

>861_bases
GTGGAGGGGACAATCGCGGTCCCGGGTGGACGCGTCTGGTTCCAGCGGATTGGTGGCGGTCCTGGTCGTCCGCTGCTTGT
AGTGCACGGTGGGCCGGGCTTGCCGCACAACTACTTGGCCCCACTGCGACGGTTGTCTGATGAGCGGGAGGTCATCTTCT
GGGACCAGCTCGGTTGCGGAAATTCCGCATGTCCGTCAGACGTAGACCTTTGGACGATGAACCGCTCAGTGGCCGAGATG
GCAACCGTGGCGGAAGCCCTTGCCCTTACCCGCTTTCACATCTTCAGCCATTCGTGGGGTGGGATGCTGGCACAGCAGTA
CGTGCTCGACAAGGCGCCTGACGCCGTCAGTCTGACCATCGCGAACAGCACGGCTTCGATACCCGAATTTTCGGCCAGTC
TGGTCAGCTTGAAGTCGTGCTTGGACGTGGCAACTCGCTCGGCAATTGACCGTCACGAGGCGGCCGGCACCACCCATTCC
GCCGAATACCAGGCCGCGATCAGAACCTGGAACGAGACTTATCTGTGCCGCACCCGCCCCTGGCCCCGGGAACTCACGGA
AGCATTCGCCAACATGGGAACCGAGATCTTCGAGACGATGTTTGGGCCCAGCGACTTTCGCATCGTTGGGAATGTTCGAG
ACTGGGACGTCGTCGACCGGTTGGCCGACATCGCGGTGCCGACCTTGCTGGTGGTGGGCCGTTTCGACGAATGTTCGCCT
GAGCACATGCGAGAAATGCAGGGCCGGATTGCGGGCTCGCGATTGGAATTCTTCGAGTCCAGTTCCCACATGCCGTTCAT
CGAAGAGCCGGCGCGATTCGACCGGGTGATGCGTGAATTCCTTCGGCTGCACGATATTTGA

Upstream 100 bases:

>100_bases
CGCTGACCGACATGCCCGGCGAGGCGACGCAAACTCGCACTCCCCCGAAGGGGCGAATGTGCGATTCTGCGTCTGTTGGT
CAACCGAAATCGGAGGTCAA

Downstream 100 bases:

>100_bases
TCTCGCCGGGCCACGTCCTGCCCGTCGTCGGCAACCAACCGCGCGAGCCTCGCGCGTGTGCCTGAGTTTATGCCCGGCAA
AGGATTTCACCGTGGGGTAT

Product: putative proline iminopeptidase pip

Products: NA

Alternate protein names: PIP; Prolyl aminopeptidase; PAP [H]

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MEGTIAVPGGRVWFQRIGGGPGRPLLVVHGGPGLPHNYLAPLRRLSDEREVIFWDQLGCGNSACPSDVDLWTMNRSVAEM
ATVAEALALTRFHIFSHSWGGMLAQQYVLDKAPDAVSLTIANSTASIPEFSASLVSLKSCLDVATRSAIDRHEAAGTTHS
AEYQAAIRTWNETYLCRTRPWPRELTEAFANMGTEIFETMFGPSDFRIVGNVRDWDVVDRLADIAVPTLLVVGRFDECSP
EHMREMQGRIAGSRLEFFESSSHMPFIEEPARFDRVMREFLRLHDI

Sequences:

>Translated_286_residues
MEGTIAVPGGRVWFQRIGGGPGRPLLVVHGGPGLPHNYLAPLRRLSDEREVIFWDQLGCGNSACPSDVDLWTMNRSVAEM
ATVAEALALTRFHIFSHSWGGMLAQQYVLDKAPDAVSLTIANSTASIPEFSASLVSLKSCLDVATRSAIDRHEAAGTTHS
AEYQAAIRTWNETYLCRTRPWPRELTEAFANMGTEIFETMFGPSDFRIVGNVRDWDVVDRLADIAVPTLLVVGRFDECSP
EHMREMQGRIAGSRLEFFESSSHMPFIEEPARFDRVMREFLRLHDI
>Mature_286_residues
MEGTIAVPGGRVWFQRIGGGPGRPLLVVHGGPGLPHNYLAPLRRLSDEREVIFWDQLGCGNSACPSDVDLWTMNRSVAEM
ATVAEALALTRFHIFSHSWGGMLAQQYVLDKAPDAVSLTIANSTASIPEFSASLVSLKSCLDVATRSAIDRHEAAGTTHS
AEYQAAIRTWNETYLCRTRPWPRELTEAFANMGTEIFETMFGPSDFRIVGNVRDWDVVDRLADIAVPTLLVVGRFDECSP
EHMREMQGRIAGSRLEFFESSSHMPFIEEPARFDRVMREFLRLHDI

Specific function: Releases the N-terminal proline from the dipeptides, Pro-Pro, Pro-Gln, Pro-Trp and Pro-Tyr. Also from amides (Pro-beta NA) and oligopeptides, Pro-Leu-GlyNH2, Pro-Leu-Gly and Pro-Phe- Gly-Lys. Higher activity toward small peptides (up to three residues), b

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S33 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR005945
- InterPro:   IPR002410 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.4.11.5 [H]

Molecular weight: Translated: 31926; Mature: 31926

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEGTIAVPGGRVWFQRIGGGPGRPLLVVHGGPGLPHNYLAPLRRLSDEREVIFWDQLGCG
CCCCEECCCCHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCEEEEECCCCC
NSACPSDVDLWTMNRSVAEMATVAEALALTRFHIFSHSWGGMLAQQYVLDKAPDAVSLTI
CCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEEE
ANSTASIPEFSASLVSLKSCLDVATRSAIDRHEAAGTTHSAEYQAAIRTWNETYLCRTRP
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEECCCC
WPRELTEAFANMGTEIFETMFGPSDFRIVGNVRDWDVVDRLADIAVPTLLVVGRFDECSP
CHHHHHHHHHHCCHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHEECCCCCCCH
EHMREMQGRIAGSRLEFFESSSHMPFIEEPARFDRVMREFLRLHDI
HHHHHHHHHHCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEGTIAVPGGRVWFQRIGGGPGRPLLVVHGGPGLPHNYLAPLRRLSDEREVIFWDQLGCG
CCCCEECCCCHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCEEEEECCCCC
NSACPSDVDLWTMNRSVAEMATVAEALALTRFHIFSHSWGGMLAQQYVLDKAPDAVSLTI
CCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEEE
ANSTASIPEFSASLVSLKSCLDVATRSAIDRHEAAGTTHSAEYQAAIRTWNETYLCRTRP
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEECCCC
WPRELTEAFANMGTEIFETMFGPSDFRIVGNVRDWDVVDRLADIAVPTLLVVGRFDECSP
CHHHHHHHHHHCCHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHEECCCCCCCH
EHMREMQGRIAGSRLEFFESSSHMPFIEEPARFDRVMREFLRLHDI
HHHHHHHHHHCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1459939 [H]