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The map label for this gene is pntAB [H]

Identifier: 121611655

GI number: 121611655

Start: 5240890

End: 5241282

Strand: Direct

Name: pntAB [H]

Synonym: Veis_4749

Alternate gene names: 121611655

Gene position: 5240890-5241282 (Clockwise)

Preceding gene: 121611654

Following gene: 121611656

Centisome position: 94.15

GC content: 65.9

Gene sequence:

>393_bases
ATGAACCGACGCCGGCGGTTGCCCCATGCAACCTGCGCGCCAGCAACGCTCAACGAAAGACCCCCGATGGACACCGTCTC
TCCCACCCTGATCAACCTGATCATCTTTGTGCTGGCCATCTACGTCGGCTACCACGTCGTGTGGACGGTCACCCCAGCCC
TGCACACGCCGCTGATGGCGCTGACCAACGCCGTTTCTGCCATCGTCATCGTCGGCGCCATGCTGGCTGCGGCCCTGACC
GAGACCCTGCTGGGCCAGAGCATGGGCGTGCTGGCCGTGGCGCTGGCCGCAGTCAACGTCTTCGGCGGCTTTCTGGTCAC
GCGGCGCATGTTGGCGATGTTCCGCAAGAAAGCCAAGCCGGCCGCGCCCCAGGCCGAAGGAGGCCGGACATGA

Upstream 100 bases:

>100_bases
TCAAACTCATCATCAACCGCGAAGGCGCGCTGCACATCGACCTGCAGGACGACATCGTTGCCGCCTGCCTGATGACGCAC
GAGGGTGCGGTCAGGCGCGC

Downstream 100 bases:

>100_bases
GCATGAACCTGGTCACGCTGCTGTATCTGGTCGCCAGCGTCTGCTTCATACAGGCCCTCAAGGGGCTGAGCCACCCCACC
ACCTCGATCCGGGGCAACCT

Product: NAD(P) transhydrogenase subunit alpha part 2

Products: NA

Alternate protein names: Nicotinamide nucleotide transhydrogenase subunit alpha 2; Proton-translocating transhydrogenase component 2; Pyridine nucleotide transhydrogenase subunit alpha 2; dII [H]

Number of amino acids: Translated: 130; Mature: 130

Protein sequence:

>130_residues
MNRRRRLPHATCAPATLNERPPMDTVSPTLINLIIFVLAIYVGYHVVWTVTPALHTPLMALTNAVSAIVIVGAMLAAALT
ETLLGQSMGVLAVALAAVNVFGGFLVTRRMLAMFRKKAKPAAPQAEGGRT

Sequences:

>Translated_130_residues
MNRRRRLPHATCAPATLNERPPMDTVSPTLINLIIFVLAIYVGYHVVWTVTPALHTPLMALTNAVSAIVIVGAMLAAALT
ETLLGQSMGVLAVALAAVNVFGGFLVTRRMLAMFRKKAKPAAPQAEGGRT
>Mature_130_residues
MNRRRRLPHATCAPATLNERPPMDTVSPTLINLIIFVLAIYVGYHVVWTVTPALHTPLMALTNAVSAIVIVGAMLAAALT
ETLLGQSMGVLAVALAAVNVFGGFLVTRRMLAMFRKKAKPAAPQAEGGRT

Specific function: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane [H]

COG id: COG3288

COG function: function code C; NAD/NADP transhydrogenase alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI122939155, Length=87, Percent_Identity=49.4252873563218, Blast_Score=88, Evalue=2e-18,
Organism=Homo sapiens, GI122939153, Length=87, Percent_Identity=49.4252873563218, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1787887, Length=102, Percent_Identity=48.0392156862745, Blast_Score=93, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17550456, Length=87, Percent_Identity=50.5747126436782, Blast_Score=91, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: =1.6.1.2 [H]

Molecular weight: Translated: 13847; Mature: 13847

Theoretical pI: Translated: 11.75; Mature: 11.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRRRRLPHATCAPATLNERPPMDTVSPTLINLIIFVLAIYVGYHVVWTVTPALHTPLMA
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
LTNAVSAIVIVGAMLAAALTETLLGQSMGVLAVALAAVNVFGGFLVTRRMLAMFRKKAKP
HHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
AAPQAEGGRT
CCCCCCCCCC
>Mature Secondary Structure
MNRRRRLPHATCAPATLNERPPMDTVSPTLINLIIFVLAIYVGYHVVWTVTPALHTPLMA
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
LTNAVSAIVIVGAMLAAALTETLLGQSMGVLAVALAAVNVFGGFLVTRRMLAMFRKKAKP
HHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
AAPQAEGGRT
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8075801 [H]