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The map label for this gene is prpC [H]

Identifier: 121611399

GI number: 121611399

Start: 4965445

End: 4966275

Strand: Direct

Name: prpC [H]

Synonym: Veis_4487

Alternate gene names: 121611399

Gene position: 4965445-4966275 (Clockwise)

Preceding gene: 121611397

Following gene: 121611403

Centisome position: 89.2

GC content: 64.74

Gene sequence:

>831_bases
ATGAGCAAAACCTACCGACTGACCGCATCCACCGCCATCCACAAAGGTGACCGGGAACACCAGCAAGACCAGGTGACACT
GATCGCCCACGCGCGGCACAAGGGCTGCGTGCTGGCGGTGGTCGCCGATGGCATGGGCGGGCGCAGCGGCGGGCGCAAAG
CCTCCGACCAGGTGATGATGACAGCGCGGCAACTGTTCGAGCGCTACTCGCCCGATACCGACGACCCGCTGGACCTGCTC
GCGCGCATCGTGCAAGAGTCCCATATCGTCATCCGGCTGACCGCGATCTCGTCCGAGCAGGAGCCCCACAGCACGATTGC
GGCCTTTCTGATCAACCCGCAGGGCGACTGCCACTGGATGCACGCGGGCGACTCGCGCATCTACCATTTCCGGGGGGCCG
AACTGGCGTTTCGCACCTGCGACCATTCCTATGTGCAGGAACTGGTCAGCCGGGGCGAACTGACCGAGGAGCAGGCCAAT
GATCACCCGCAATCGAACATCCTGATCCACTGCCTGGGCGCCGACAGCGATCCCCCGCTGACCAGCCATCTGATTGCGCA
GTTGCAGCCGGGCGATGCGCTGCTCGCTTGCAGCGACGGTGTCTGGCATTACTTCACGACGGCCGAGCTGGCCGCCGTGG
TCGATGCGCTGTCACCCCGGGAAGCAACGCAGATACTGATAGAAAAAGCCCGCACCCGGGCCCGTGGGGATGGCGACAAC
CTGTCGCTGGTCATCGTCAAAATCGAAGCGCGACAGGAAGAAGAAACCATACCGGCCAGCCTCCCCCCTCTGGCCGCGCA
TGAAGGGCCCTCCCCGGTGCGCACCGGCTGA

Upstream 100 bases:

>100_bases
ATGGAGAAAGAAGCAAGTGTTACAAGCGGGTGGATAATACGTCTTTATCCTGCCGTCTACGGCTGCCCTGTGCATGTCCG
GCGCCCACGACCACATCTGC

Downstream 100 bases:

>100_bases
TTCCACCAAGGGCCTTGGCAACTCATCATTTCTCGATTCCATTTCCATCGAGACTTTCGCAAATCATGACGAGTGGCTGC
ACCCGATTGCTCCCATGAGA

Product: protein phosphatase 2C domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 276; Mature: 275

Protein sequence:

>276_residues
MSKTYRLTASTAIHKGDREHQQDQVTLIAHARHKGCVLAVVADGMGGRSGGRKASDQVMMTARQLFERYSPDTDDPLDLL
ARIVQESHIVIRLTAISSEQEPHSTIAAFLINPQGDCHWMHAGDSRIYHFRGAELAFRTCDHSYVQELVSRGELTEEQAN
DHPQSNILIHCLGADSDPPLTSHLIAQLQPGDALLACSDGVWHYFTTAELAAVVDALSPREATQILIEKARTRARGDGDN
LSLVIVKIEARQEEETIPASLPPLAAHEGPSPVRTG

Sequences:

>Translated_276_residues
MSKTYRLTASTAIHKGDREHQQDQVTLIAHARHKGCVLAVVADGMGGRSGGRKASDQVMMTARQLFERYSPDTDDPLDLL
ARIVQESHIVIRLTAISSEQEPHSTIAAFLINPQGDCHWMHAGDSRIYHFRGAELAFRTCDHSYVQELVSRGELTEEQAN
DHPQSNILIHCLGADSDPPLTSHLIAQLQPGDALLACSDGVWHYFTTAELAAVVDALSPREATQILIEKARTRARGDGDN
LSLVIVKIEARQEEETIPASLPPLAAHEGPSPVRTG
>Mature_275_residues
SKTYRLTASTAIHKGDREHQQDQVTLIAHARHKGCVLAVVADGMGGRSGGRKASDQVMMTARQLFERYSPDTDDPLDLLA
RIVQESHIVIRLTAISSEQEPHSTIAAFLINPQGDCHWMHAGDSRIYHFRGAELAFRTCDHSYVQELVSRGELTEEQAND
HPQSNILIHCLGADSDPPLTSHLIAQLQPGDALLACSDGVWHYFTTAELAAVVDALSPREATQILIEKARTRARGDGDNL
SLVIVKIEARQEEETIPASLPPLAAHEGPSPVRTG

Specific function: Protein phosphatase that dephosphorylates prkC and fusA (elongation factor G). PrpC and prkC are cotranscribed, which suggests that they form a functional couple in vivo, prpC's primary role being possibly to counter the action of prkC. May be involved in

COG id: COG0631

COG function: function code T; Serine/threonine protein phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015655
- InterPro:   IPR001932
- InterPro:   IPR014045 [H]

Pfam domain/function: PF00481 PP2C [H]

EC number: =3.1.3.16 [H]

Molecular weight: Translated: 30200; Mature: 30069

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKTYRLTASTAIHKGDREHQQDQVTLIAHARHKGCVLAVVADGMGGRSGGRKASDQVMM
CCCEEEEEHHHHHHCCCCHHCCCEEEEEEECCCCCEEEEEEECCCCCCCCCCCHHHHHHH
TARQLFERYSPDTDDPLDLLARIVQESHIVIRLTAISSEQEPHSTIAAFLINPQGDCHWM
HHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEEEEEECCCCCCCCEEEEEEECCCCCEEEE
HAGDSRIYHFRGAELAFRTCDHSYVQELVSRGELTEEQANDHPQSNILIHCLGADSDPPL
ECCCCEEEEEECCCEEEECCCHHHHHHHHHCCCCCHHHHCCCCCCCEEEEEECCCCCCCH
TSHLIAQLQPGDALLACSDGVWHYFTTAELAAVVDALSPREATQILIEKARTRARGDGDN
HHHHHHHCCCCCEEEEECCCCEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCC
LSLVIVKIEARQEEETIPASLPPLAAHEGPSPVRTG
EEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SKTYRLTASTAIHKGDREHQQDQVTLIAHARHKGCVLAVVADGMGGRSGGRKASDQVMM
CCEEEEEHHHHHHCCCCHHCCCEEEEEEECCCCCEEEEEEECCCCCCCCCCCHHHHHHH
TARQLFERYSPDTDDPLDLLARIVQESHIVIRLTAISSEQEPHSTIAAFLINPQGDCHWM
HHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEEEEEECCCCCCCCEEEEEEECCCCCEEEE
HAGDSRIYHFRGAELAFRTCDHSYVQELVSRGELTEEQANDHPQSNILIHCLGADSDPPL
ECCCCEEEEEECCCEEEECCCHHHHHHHHHCCCCCHHHHCCCCCCCEEEEEECCCCCCCH
TSHLIAQLQPGDALLACSDGVWHYFTTAELAAVVDALSPREATQILIEKARTRARGDGDN
HHHHHHHCCCCCEEEEECCCCEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCC
LSLVIVKIEARQEEETIPASLPPLAAHEGPSPVRTG
EEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]