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The map label for this gene is clpX [H]

Identifier: 121611286

GI number: 121611286

Start: 4820600

End: 4821943

Strand: Direct

Name: clpX [H]

Synonym: Veis_4372

Alternate gene names: 121611286

Gene position: 4820600-4821943 (Clockwise)

Preceding gene: 121611285

Following gene: 121611287

Centisome position: 86.6

GC content: 60.42

Gene sequence:

>1344_bases
TTGTCCTGTTGGGCAGGGCGCCACTGTCATTTGGTTATCATCCCGACCACTTTCCGTCACAAGCAAGGCATTGCCCCCAT
GGCCGAGATAAAAGGCGCCCCCAGCGAAAAATCCCTTTACTGCTCTTTCTGCAGCAAAAGCCAGCATGAAGTGCGAAAGC
TGATCGCTGGCCCGTCGGTCTTTATCTGCGACGAGTGCATCGACCTGTGCAACGAGATCATCCGCCATGACTTGCCGGTG
GCTCATCCGGCGCGGGAAATCCTCAATGGCCTGCCCACCCCGGCAGAGATCAAGAACAACCTGGACAACTATGTGATCGG
CCAGGAGGAGGCCAAGCGCACGCTGGCCGTGGCGGTGTACAACCACTACAAGCGCCTGCGCTACAAGGAAAAGGCGCGCA
AGAACGATGTCGAGCTGTCCAAGAGCAACATCTTGCTGATCGGCCCCACAGGCTCGGGCAAGACGCTGCTGGCGCAAACC
CTGGCCCGCATGCTCGATGTGCCCTTCGTGATGGCAGACGCCACGACGCTGACCGAGGCCGGTTATGTGGGCGAAGATGT
GGAGAACATCATCCAGAAGCTGCTGCAAAGCTGCGGCTACAAAGTCGAACCGGCCCAGCGCGGCATCGTCTACATCGACG
AGATCGACAAGATCTCGCGCAAGTCGGACAACCCCAGCATCACCCGCGATGTATCGGGCGAGGGGGTGCAGCAGGCGTTG
CTCAAGCTCATCGAAGGCACCATGGTCAGCGTGCCGCCGCAGGGCGGGCGCAAGCACCCGAACCAGGACTTCCTGCAAAT
CGACACCAGCGACATCCTGTTCATTTGCGGAGGCGCGTTTGCCGGGCTGGAAAAGGTCATAGAAAACCGCACCGAAGCCT
CGGGCATCGGTTTCGGCGCCTCGGTCAAAAGCAAAAAGCAGCGCTCGCTGACCGATGTGTTTGCCGAGGTCGAACCGGAA
GACCTGATCAAGTTCGGCCTGATCCCCGAGTTGGTGGGCCGCATGCCGGTGGTGACGGCCCTGGCCGAACTGAGCGAGCA
AGCGCTGATACAGATCCTGACCGAGCCGAGAAACGCGCTGATCAAGCAGTACGGCAAGCTGTTGGCGATGGAAGGCGTGA
ACCTGGAGATTCGCCCGGCAGCGATGCAGTCGATTGCCCGCAAGGCCCTGGCACGCAAGACCGGCGCCCGCGGCCTGCGC
TCGATCCTGGAGCAATCGCTGATCGGCACCATGTTCGACCTGCCCAACACCAGCAATGTCGAAAGGGTGGTGATCGACGA
GTCCACCATCGAAGAAAACAAACCCCCGCTGCTCGTTTACCGCGAGACGGCCAGGAAAGCCTGA

Upstream 100 bases:

>100_bases
GAGCGCGACTATTTCCTGTCGGCCGACGAGTCGCGGGAATACGGTCTGGTCGATCAGGTGATCCACCGACGATCCTGACG
CCCGCCGGGTCACGGCGGCA

Downstream 100 bases:

>100_bases
AATCCCCGGATCGCGGGCGCCTTTGCTGCCCGCAGCCCCTGCACCCCGGATACAGTTGCCGTGCAAGGGATTGAAAAACC
CCGCTTGCGGGCCATATTCC

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 447; Mature: 446

Protein sequence:

>447_residues
MSCWAGRHCHLVIIPTTFRHKQGIAPMAEIKGAPSEKSLYCSFCSKSQHEVRKLIAGPSVFICDECIDLCNEIIRHDLPV
AHPAREILNGLPTPAEIKNNLDNYVIGQEEAKRTLAVAVYNHYKRLRYKEKARKNDVELSKSNILLIGPTGSGKTLLAQT
LARMLDVPFVMADATTLTEAGYVGEDVENIIQKLLQSCGYKVEPAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQAL
LKLIEGTMVSVPPQGGRKHPNQDFLQIDTSDILFICGGAFAGLEKVIENRTEASGIGFGASVKSKKQRSLTDVFAEVEPE
DLIKFGLIPELVGRMPVVTALAELSEQALIQILTEPRNALIKQYGKLLAMEGVNLEIRPAAMQSIARKALARKTGARGLR
SILEQSLIGTMFDLPNTSNVERVVIDESTIEENKPPLLVYRETARKA

Sequences:

>Translated_447_residues
MSCWAGRHCHLVIIPTTFRHKQGIAPMAEIKGAPSEKSLYCSFCSKSQHEVRKLIAGPSVFICDECIDLCNEIIRHDLPV
AHPAREILNGLPTPAEIKNNLDNYVIGQEEAKRTLAVAVYNHYKRLRYKEKARKNDVELSKSNILLIGPTGSGKTLLAQT
LARMLDVPFVMADATTLTEAGYVGEDVENIIQKLLQSCGYKVEPAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQAL
LKLIEGTMVSVPPQGGRKHPNQDFLQIDTSDILFICGGAFAGLEKVIENRTEASGIGFGASVKSKKQRSLTDVFAEVEPE
DLIKFGLIPELVGRMPVVTALAELSEQALIQILTEPRNALIKQYGKLLAMEGVNLEIRPAAMQSIARKALARKTGARGLR
SILEQSLIGTMFDLPNTSNVERVVIDESTIEENKPPLLVYRETARKA
>Mature_446_residues
SCWAGRHCHLVIIPTTFRHKQGIAPMAEIKGAPSEKSLYCSFCSKSQHEVRKLIAGPSVFICDECIDLCNEIIRHDLPVA
HPAREILNGLPTPAEIKNNLDNYVIGQEEAKRTLAVAVYNHYKRLRYKEKARKNDVELSKSNILLIGPTGSGKTLLAQTL
ARMLDVPFVMADATTLTEAGYVGEDVENIIQKLLQSCGYKVEPAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALL
KLIEGTMVSVPPQGGRKHPNQDFLQIDTSDILFICGGAFAGLEKVIENRTEASGIGFGASVKSKKQRSLTDVFAEVEPED
LIKFGLIPELVGRMPVVTALAELSEQALIQILTEPRNALIKQYGKLLAMEGVNLEIRPAAMQSIARKALARKTGARGLRS
ILEQSLIGTMFDLPNTSNVERVVIDESTIEENKPPLLVYRETARKA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=326, Percent_Identity=50.3067484662577, Blast_Score=302, Evalue=4e-82,
Organism=Escherichia coli, GI1786642, Length=416, Percent_Identity=72.1153846153846, Blast_Score=607, Evalue=1e-175,
Organism=Escherichia coli, GI1790366, Length=106, Percent_Identity=44.3396226415094, Blast_Score=102, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI71982905, Length=311, Percent_Identity=46.3022508038585, Blast_Score=275, Evalue=3e-74,
Organism=Caenorhabditis elegans, GI71982908, Length=309, Percent_Identity=45.9546925566343, Blast_Score=275, Evalue=4e-74,
Organism=Caenorhabditis elegans, GI71988663, Length=407, Percent_Identity=39.3120393120393, Blast_Score=259, Evalue=3e-69,
Organism=Caenorhabditis elegans, GI71988660, Length=248, Percent_Identity=43.5483870967742, Blast_Score=184, Evalue=9e-47,
Organism=Saccharomyces cerevisiae, GI6319704, Length=432, Percent_Identity=38.4259259259259, Blast_Score=270, Evalue=2e-73,
Organism=Drosophila melanogaster, GI24648289, Length=321, Percent_Identity=46.1059190031153, Blast_Score=278, Evalue=5e-75,
Organism=Drosophila melanogaster, GI24648291, Length=321, Percent_Identity=46.1059190031153, Blast_Score=278, Evalue=5e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 49223; Mature: 49091

Theoretical pI: Translated: 7.72; Mature: 7.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSCWAGRHCHLVIIPTTFRHKQGIAPMAEIKGAPSEKSLYCSFCSKSQHEVRKLIAGPSV
CCCCCCCCEEEEEECCCHHHHCCCCCHHHHCCCCCCCCEEHHHHCCCHHHHHHHHCCCCE
FICDECIDLCNEIIRHDLPVAHPAREILNGLPTPAEIKNNLDNYVIGQEEAKRTLAVAVY
EEHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHH
NHYKRLRYKEKARKNDVELSKSNILLIGPTGSGKTLLAQTLARMLDVPFVMADATTLTEA
HHHHHHHHHHHHHCCCCEECCCCEEEEECCCCCHHHHHHHHHHHHCCCEEEECCHHHHHC
GYVGEDVENIIQKLLQSCGYKVEPAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQAL
CCCCHHHHHHHHHHHHHCCCEECCCCCCEEEEECHHHHHCCCCCCCCCCCCCCCHHHHHH
LKLIEGTMVSVPPQGGRKHPNQDFLQIDTSDILFICGGAFAGLEKVIENRTEASGIGFGA
HHHHCCCEEECCCCCCCCCCCCCEEEECCCCEEEEECCHHHHHHHHHHCCCCCCCCCCCC
SVKSKKQRSLTDVFAEVEPEDLIKFGLIPELVGRMPVVTALAELSEQALIQILTEPRNAL
CCHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IKQYGKLLAMEGVNLEIRPAAMQSIARKALARKTGARGLRSILEQSLIGTMFDLPNTSNV
HHHHHHHHEECCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
ERVVIDESTIEENKPPLLVYRETARKA
EEEEEECHHHCCCCCCEEEEECCCCCC
>Mature Secondary Structure 
SCWAGRHCHLVIIPTTFRHKQGIAPMAEIKGAPSEKSLYCSFCSKSQHEVRKLIAGPSV
CCCCCCCEEEEEECCCHHHHCCCCCHHHHCCCCCCCCEEHHHHCCCHHHHHHHHCCCCE
FICDECIDLCNEIIRHDLPVAHPAREILNGLPTPAEIKNNLDNYVIGQEEAKRTLAVAVY
EEHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHH
NHYKRLRYKEKARKNDVELSKSNILLIGPTGSGKTLLAQTLARMLDVPFVMADATTLTEA
HHHHHHHHHHHHHCCCCEECCCCEEEEECCCCCHHHHHHHHHHHHCCCEEEECCHHHHHC
GYVGEDVENIIQKLLQSCGYKVEPAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQAL
CCCCHHHHHHHHHHHHHCCCEECCCCCCEEEEECHHHHHCCCCCCCCCCCCCCCHHHHHH
LKLIEGTMVSVPPQGGRKHPNQDFLQIDTSDILFICGGAFAGLEKVIENRTEASGIGFGA
HHHHCCCEEECCCCCCCCCCCCCEEEECCCCEEEEECCHHHHHHHHHHCCCCCCCCCCCC
SVKSKKQRSLTDVFAEVEPEDLIKFGLIPELVGRMPVVTALAELSEQALIQILTEPRNAL
CCHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IKQYGKLLAMEGVNLEIRPAAMQSIARKALARKTGARGLRSILEQSLIGTMFDLPNTSNV
HHHHHHHHEECCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
ERVVIDESTIEENKPPLLVYRETARKA
EEEEEECHHHCCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA